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The map label for this gene is mmoC [H]

Identifier: 170749799

GI number: 170749799

Start: 3608572

End: 3609351

Strand: Reverse

Name: mmoC [H]

Synonym: Mrad2831_3398

Alternate gene names: 170749799

Gene position: 3609351-3608572 (Counterclockwise)

Preceding gene: 170749800

Following gene: 170749797

Centisome position: 59.39

GC content: 73.85

Gene sequence:

>780_bases
GTGACTGAAACGGTGGCTGAAGCGGTGCCTGGCGCGGTGACGGACAGGGAAGCGGACCCGGCGATCGAGCCCATCGTCTT
CCGCTGGCACGAGGCGGAGATCGCCGCGATCGCGCCGGTCACGCCGCACGTGAAGAGCGTCCGGCTGCGCTGCGGACTCG
CCGAGGCCTACCGGGCCGGGCAGCACGTCGATGTCCGGCTCACCGCGGAGGACGGCTACCAGGCGCAGCGCAGCTACTCC
ATCGCCTCGGCGCAGGACGGCAGCGGCACCCTGGAGCTGATGATCGAGGGCCTGCCGGACGGCGAGGTCTCGGGCTGGTT
CTCGCACTGCGCCGAGGTCGGCGACCGGGTCGAACTGCGTGGGCCGATCGGCGGCTCGTTCTCCTGGGACGGACCTGACG
GCGGGCCCCTGCTCCTGGGCGGCGGCGGCTCCGGCGTGGTACCGCTCCTGGCGATGCTGCGGCGGCGGGCGCAGAACTGG
CGGGCGATCCCGGCGGCGCTGATCTACTCGGCCCGCACCCGCGCGGAGGCGATCGCGGTCGCCGAGCTGGAACGGCTCGC
CGAGACGGACCCCAACTTCTCCCTGCATCTCGCCACGACGCGCGAGCCCGGCGGCAGGCGGATCGACGCGCCCCTCGTCG
CCGACGCCCTCGCGCGGATCGGGGCACCCGGGAAGGTGTTCCTCTGCGGCTCGAACCGCTTCGTGGCCGCGGCCTCCGAC
CTGATCCTGGCGCAGGGCGTCGCGCCGGGCCTGATCCGGACCGAACGCTTCGGCGCCTGA

Upstream 100 bases:

>100_bases
GTGAAGGGCCTCCGGTTCACCCAGACCGACACCGCCGGCTTCTGGGAGCTGCGCGGCTACCACATGTACGGGGATCCCTG
GCGTGAGCAGCGCTACATCG

Downstream 100 bases:

>100_bases
AGGCGCCGCGATCTTCCGCATCGGAGGGGACGTCGGCGCGGTCGTCCCGCGAGCGGAGCGATCCGGACGGTGCCACCCCC
GTCGAGGCCGCGCTGCCCTG

Product: oxidoreductase FAD-binding subunit

Products: NA

Alternate protein names: Methane hydroxylase; Methane monooxygenase reductase; MMOR [H]

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MTETVAEAVPGAVTDREADPAIEPIVFRWHEAEIAAIAPVTPHVKSVRLRCGLAEAYRAGQHVDVRLTAEDGYQAQRSYS
IASAQDGSGTLELMIEGLPDGEVSGWFSHCAEVGDRVELRGPIGGSFSWDGPDGGPLLLGGGGSGVVPLLAMLRRRAQNW
RAIPAALIYSARTRAEAIAVAELERLAETDPNFSLHLATTREPGGRRIDAPLVADALARIGAPGKVFLCGSNRFVAAASD
LILAQGVAPGLIRTERFGA

Sequences:

>Translated_259_residues
MTETVAEAVPGAVTDREADPAIEPIVFRWHEAEIAAIAPVTPHVKSVRLRCGLAEAYRAGQHVDVRLTAEDGYQAQRSYS
IASAQDGSGTLELMIEGLPDGEVSGWFSHCAEVGDRVELRGPIGGSFSWDGPDGGPLLLGGGGSGVVPLLAMLRRRAQNW
RAIPAALIYSARTRAEAIAVAELERLAETDPNFSLHLATTREPGGRRIDAPLVADALARIGAPGKVFLCGSNRFVAAASD
LILAQGVAPGLIRTERFGA
>Mature_258_residues
TETVAEAVPGAVTDREADPAIEPIVFRWHEAEIAAIAPVTPHVKSVRLRCGLAEAYRAGQHVDVRLTAEDGYQAQRSYSI
ASAQDGSGTLELMIEGLPDGEVSGWFSHCAEVGDRVELRGPIGGSFSWDGPDGGPLLLGGGGSGVVPLLAMLRRRAQNWR
AIPAALIYSARTRAEAIAVAELERLAETDPNFSLHLATTREPGGRRIDAPLVADALARIGAPGKVFLCGSNRFVAAASDL
ILAQGVAPGLIRTERFGA

Specific function: Responsible for the initial oxygenation of methane to methanol in methanotrophs. It also catalyzes the monohydroxylation of a variety of unactivated alkenes, alicyclic, aromatic and heterocyclic compounds. The component C is the iron-sulfur flavoprotein o

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=237, Percent_Identity=26.1603375527426, Blast_Score=64, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6323510, Length=143, Percent_Identity=32.8671328671329, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: =1.14.13.25 [H]

Molecular weight: Translated: 27310; Mature: 27179

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETVAEAVPGAVTDREADPAIEPIVFRWHEAEIAAIAPVTPHVKSVRLRCGLAEAYRAG
CCCHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEECCCCCCHHHHHHHCCHHHHHHCC
QHVDVRLTAEDGYQAQRSYSIASAQDGSGTLELMIEGLPDGEVSGWFSHCAEVGDRVELR
CCEEEEEECCCCCCHHHCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCEEEEE
GPIGGSFSWDGPDGGPLLLGGGGSGVVPLLAMLRRRAQNWRAIPAALIYSARTRAEAIAV
CCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
AELERLAETDPNFSLHLATTREPGGRRIDAPLVADALARIGAPGKVFLCGSNRFVAAASD
HHHHHHHHCCCCEEEEEEECCCCCCCEECCHHHHHHHHHCCCCCEEEEECCCCEEEHHHH
LILAQGVAPGLIRTERFGA
HHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TETVAEAVPGAVTDREADPAIEPIVFRWHEAEIAAIAPVTPHVKSVRLRCGLAEAYRAG
CCHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEECCCCCCHHHHHHHCCHHHHHHCC
QHVDVRLTAEDGYQAQRSYSIASAQDGSGTLELMIEGLPDGEVSGWFSHCAEVGDRVELR
CCEEEEEECCCCCCHHHCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCEEEEE
GPIGGSFSWDGPDGGPLLLGGGGSGVVPLLAMLRRRAQNWRAIPAALIYSARTRAEAIAV
CCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
AELERLAETDPNFSLHLATTREPGGRRIDAPLVADALARIGAPGKVFLCGSNRFVAAASD
HHHHHHHHCCCCEEEEEEECCCCCCCEECCHHHHHHHHHCCCCCEEEEECCCCEEEHHHH
LILAQGVAPGLIRTERFGA
HHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1785954 [H]