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The map label for this gene is yhcS [C]

Identifier: 170749729

GI number: 170749729

Start: 3529940

End: 3530830

Strand: Direct

Name: yhcS [C]

Synonym: Mrad2831_3328

Alternate gene names: 170749729

Gene position: 3529940-3530830 (Clockwise)

Preceding gene: 170749728

Following gene: 170749730

Centisome position: 58.08

GC content: 71.49

Gene sequence:

>891_bases
ATGGATCGGTGGCAGGCCATGCGCATCTTCGCCAAGGTCGCCGAGACGGCGAGCTTCGCGCAGACCGCCCGGCTCCTGCA
CATGAGCCCGCCGGCCGTGACGCGCGCCGTGGCCGCGCTCGAGGAGACCATCGGCGCCCGCCTCCTGATCCGGACGACCC
GCTCCGTGAAGCTCACGGAGGCGGGCAGCCGGTACTACGAGGATTGCCGGCGGATCCTGGCCGACATCGCCGAGGCGGAA
TCGGCGGCGGCCGGCTCCAACGCGACGCCCTCGGGCACGCTCGCGGTGACGGCCTCGGTCCTGTTCGGGCGGATGCACGT
GCTCCCGATCGTCACCGACTACCTCGACACCTACCCCACCATGGCGGCACGGACCCTCTTCGTCGACCGGCCGGTGAGCA
TCGTCGAGGAAGGGATCGACGTAGCGATCCGCATCGGCCACCTGACCGATTCCGGGTTCACCGCAGCCCGCGTCGGGTCG
GTGCGCCACGTCATCTGCGGCGCCCCGGACTACTTCGTGCGGCACGGCGTGCCGACGACGCCGGCGGATCTGAAGCGGCA
CCGGATCGCCGTCTCCACCGGCGCCTTCGCGTCGCCGGAATGGCGGTTCGGCCGAAACGAGCGGGTGGTCATTCACCCGA
CCCTGCAGGGCAACACCAACGAGGTCTCGATCGGCGCCGCCCGGTCGGGCTGGGGGCTGGCGCGGGTCCTGAACTACCAG
ATCGGCCCGGACCTGCGGGACGGCCGCCTGCAGATCGTGCTCGCCGAGTACGAGGAGGCGCCGCTGCCCGTCCACGTGCT
CTACCCGGAAGGCCGGCACGCGCCCGCCAAGGTTCGGACCTTCGTCGACCTGGCGGTGTCGCGCCTGCGCGCCAACCCGA
CGCTGAACTGA

Upstream 100 bases:

>100_bases
GAGCCATTTCGGCTTCTGACCGCCCGGCCGACACGCCGACACGACAGGCCGGGCCGGGTGTGAGCGTCGCGACCCGGCCG
CGAAACCCCGGAGCGAAGCC

Downstream 100 bases:

>100_bases
GGGCGCGCCGGGCCGGCGAGGGCCGTTCTGGTCGCTCGGGTCGTATTGGTCGCAGCCGCGGCCAGGAAAGGATGTTTCAG
TCTTAAGTTAGTTTTTTAGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MDRWQAMRIFAKVAETASFAQTARLLHMSPPAVTRAVAALEETIGARLLIRTTRSVKLTEAGSRYYEDCRRILADIAEAE
SAAAGSNATPSGTLAVTASVLFGRMHVLPIVTDYLDTYPTMAARTLFVDRPVSIVEEGIDVAIRIGHLTDSGFTAARVGS
VRHVICGAPDYFVRHGVPTTPADLKRHRIAVSTGAFASPEWRFGRNERVVIHPTLQGNTNEVSIGAARSGWGLARVLNYQ
IGPDLRDGRLQIVLAEYEEAPLPVHVLYPEGRHAPAKVRTFVDLAVSRLRANPTLN

Sequences:

>Translated_296_residues
MDRWQAMRIFAKVAETASFAQTARLLHMSPPAVTRAVAALEETIGARLLIRTTRSVKLTEAGSRYYEDCRRILADIAEAE
SAAAGSNATPSGTLAVTASVLFGRMHVLPIVTDYLDTYPTMAARTLFVDRPVSIVEEGIDVAIRIGHLTDSGFTAARVGS
VRHVICGAPDYFVRHGVPTTPADLKRHRIAVSTGAFASPEWRFGRNERVVIHPTLQGNTNEVSIGAARSGWGLARVLNYQ
IGPDLRDGRLQIVLAEYEEAPLPVHVLYPEGRHAPAKVRTFVDLAVSRLRANPTLN
>Mature_296_residues
MDRWQAMRIFAKVAETASFAQTARLLHMSPPAVTRAVAALEETIGARLLIRTTRSVKLTEAGSRYYEDCRRILADIAEAE
SAAAGSNATPSGTLAVTASVLFGRMHVLPIVTDYLDTYPTMAARTLFVDRPVSIVEEGIDVAIRIGHLTDSGFTAARVGS
VRHVICGAPDYFVRHGVPTTPADLKRHRIAVSTGAFASPEWRFGRNERVVIHPTLQGNTNEVSIGAARSGWGLARVLNYQ
IGPDLRDGRLQIVLAEYEEAPLPVHVLYPEGRHAPAKVRTFVDLAVSRLRANPTLN

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=289, Percent_Identity=31.1418685121107, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI145693193, Length=288, Percent_Identity=30.9027777777778, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1786401, Length=292, Percent_Identity=30.1369863013699, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1787128, Length=276, Percent_Identity=27.8985507246377, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1789440, Length=282, Percent_Identity=26.5957446808511, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI87081978, Length=286, Percent_Identity=31.1188811188811, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787589, Length=282, Percent_Identity=32.9787234042553, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1789173, Length=249, Percent_Identity=24.8995983935743, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788706, Length=245, Percent_Identity=25.7142857142857, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI145693105, Length=124, Percent_Identity=33.0645161290323, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787879, Length=100, Percent_Identity=40, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI157672245, Length=112, Percent_Identity=29.4642857142857, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32272; Mature: 32272

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRWQAMRIFAKVAETASFAQTARLLHMSPPAVTRAVAALEETIGARLLIRTTRSVKLTE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCEEEEH
AGSRYYEDCRRILADIAEAESAAAGSNATPSGTLAVTASVLFGRMHVLPIVTDYLDTYPT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHH
MAARTLFVDRPVSIVEEGIDVAIRIGHLTDSGFTAARVGSVRHVICGAPDYFVRHGVPTT
HHHHEEEECCCHHHHHCCCEEEEEEEEECCCCCCHHHHCCEEEEEECCCHHHHHCCCCCC
PADLKRHRIAVSTGAFASPEWRFGRNERVVIHPTLQGNTNEVSIGAARSGWGLARVLNYQ
HHHHHHCEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCCCCCHHHHHHHC
IGPDLRDGRLQIVLAEYEEAPLPVHVLYPEGRHAPAKVRTFVDLAVSRLRANPTLN
CCCCCCCCEEEEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDRWQAMRIFAKVAETASFAQTARLLHMSPPAVTRAVAALEETIGARLLIRTTRSVKLTE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCEEEEH
AGSRYYEDCRRILADIAEAESAAAGSNATPSGTLAVTASVLFGRMHVLPIVTDYLDTYPT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHH
MAARTLFVDRPVSIVEEGIDVAIRIGHLTDSGFTAARVGSVRHVICGAPDYFVRHGVPTT
HHHHEEEECCCHHHHHCCCEEEEEEEEECCCCCCHHHHCCEEEEEECCCHHHHHCCCCCC
PADLKRHRIAVSTGAFASPEWRFGRNERVVIHPTLQGNTNEVSIGAARSGWGLARVLNYQ
HHHHHHCEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCCCCCHHHHHHHC
IGPDLRDGRLQIVLAEYEEAPLPVHVLYPEGRHAPAKVRTFVDLAVSRLRANPTLN
CCCCCCCCEEEEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]