BacMap

Definition	Methylobacterium radiotolerans JCM 2831 chromosome, complete genome.
Accession	NC_010505
Length	6,077,833

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The map label for this gene is fabG [H]

Identifier: 170749717

GI number: 170749717

Start: 3517733

End: 3518494

Strand: Reverse

Name: fabG [H]

Synonym: Mrad2831_3316

Alternate gene names: 170749717

Gene position: 3518494-3517733 (Counterclockwise)

Preceding gene: 170749718

Following gene: 170749716

Centisome position: 57.89

GC content: 74.8

Gene sequence:

>762_bases
ATGGATCTCGGGCTGAGAGGCCGCCGGGCGCTGGTGACCGGCGGCACCAAGGGGATCGGCGCGGCGATCGTCGACCTGCT
GGCCGACGAGGGGGCCGCGGTCGCCCTCTGCGCCCGCAACGCCGCGGAGGTCGCCGCCAAGGTGGCGGCCCTGCGTGCCA
GGGGCGTGGCGGCGACCGGGCGCGCCGTCGACGTCGCCGATTCCGCGGCCCTGCGCGGCTGGGTCGCGGAGGCCGCGGAG
GAGCTCGGCGGCCTCGACATCGTGGTGCCGAACGTCAGCGCCCTCGCGGTCGGCGGCGACGAGGCGGCGTGGCGGAGCGG
CTTCGCCGTGGACATGATGGGCACCGTCTCGGCGGTCGAGGCGGCGATGCCGTACCTCGAGCGCTCCGAGGCGGGCGCGA
TCGTCGTCATCTCCAGCGTCTCCGGCCGCGAGATCGACTTCGCGGCCGGTCCCTACGGCGCCTTCAAGGCCGCGCTGATC
CACTACGCGCAGGGCCTCGCCTTCCAGCTCGCGCCCCGGAACATCCGCGCCAACTCGGTCTCGCCCGGCAACACCTACTT
CGCGGGCGGCGTCTGGCACCAGATCGAGACCGGCAACCCGGCGCTGTTCGCCGAGGCGCTCCGGCTGAACCCGACCGGCC
GGATGGCGCGGCCCGAGGAGGTGGCGCGCGCGGCCGTCTTCCTGGCGAGCCCGGCCGCCAGCTTCATCACCGGAACCAAC
CTCGTGGTCGACGGCAGCCTGACCCGCGGCGTGCAGTTCTGA

Upstream 100 bases:

>100_bases
GCGCGTCCGGCTCGGCAACATGGTCGATCCGAAATACACGCTCGGCGCCTCGATCACGAAGGCGATCGCCCACGCCTGAT
CGGCGACGGAGGAGGACGGC

Downstream 100 bases:

>100_bases
CGCCGATCGGCCTCGCCCCGCGCCGGGACACCTGGGGCTTCCGAAGCACACCCGGCGCGTTCAGCACGGTCGTTCAGCGA
GGAAGTCCGGAGATCGCGAG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MDLGLRGRRALVTGGTKGIGAAIVDLLADEGAAVALCARNAAEVAAKVAALRARGVAATGRAVDVADSAALRGWVAEAAE
ELGGLDIVVPNVSALAVGGDEAAWRSGFAVDMMGTVSAVEAAMPYLERSEAGAIVVISSVSGREIDFAAGPYGAFKAALI
HYAQGLAFQLAPRNIRANSVSPGNTYFAGGVWHQIETGNPALFAEALRLNPTGRMARPEEVARAAVFLASPAASFITGTN
LVVDGSLTRGVQF

Sequences:

>Translated_253_residues
MDLGLRGRRALVTGGTKGIGAAIVDLLADEGAAVALCARNAAEVAAKVAALRARGVAATGRAVDVADSAALRGWVAEAAE
ELGGLDIVVPNVSALAVGGDEAAWRSGFAVDMMGTVSAVEAAMPYLERSEAGAIVVISSVSGREIDFAAGPYGAFKAALI
HYAQGLAFQLAPRNIRANSVSPGNTYFAGGVWHQIETGNPALFAEALRLNPTGRMARPEEVARAAVFLASPAASFITGTN
LVVDGSLTRGVQF
>Mature_253_residues
MDLGLRGRRALVTGGTKGIGAAIVDLLADEGAAVALCARNAAEVAAKVAALRARGVAATGRAVDVADSAALRGWVAEAAE
ELGGLDIVVPNVSALAVGGDEAAWRSGFAVDMMGTVSAVEAAMPYLERSEAGAIVVISSVSGREIDFAAGPYGAFKAALI
HYAQGLAFQLAPRNIRANSVSPGNTYFAGGVWHQIETGNPALFAEALRLNPTGRMARPEEVARAAVFLASPAASFITGTN
LVVDGSLTRGVQF

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=33.4677419354839, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI5031737, Length=252, Percent_Identity=33.3333333333333, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=29.8804780876494, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI33667109, Length=184, Percent_Identity=33.695652173913, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI59889578, Length=191, Percent_Identity=33.5078534031414, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=31.8181818181818, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=32.0441988950276, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI19923817, Length=253, Percent_Identity=27.6679841897233, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI10190704, Length=252, Percent_Identity=29.7619047619048, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI15277342, Length=259, Percent_Identity=32.046332046332, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7705925, Length=250, Percent_Identity=29.2, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI4503817, Length=242, Percent_Identity=26.0330578512397, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=28.2258064516129, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=32.5490196078431, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=30.6772908366534, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=29.1828793774319, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=30.3501945525292, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=30.3149606299213, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=26.1044176706827, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI2367365, Length=253, Percent_Identity=33.201581027668, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87082160, Length=252, Percent_Identity=27.3809523809524, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=26.1044176706827, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=30.4, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=32.4, Blast_Score=111, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI193204405, Length=276, Percent_Identity=30.4347826086957, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=32.5670498084291, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=30.7116104868914, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=28.515625, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17560332, Length=259, Percent_Identity=30.8880308880309, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=30.6818181818182, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17531453, Length=270, Percent_Identity=31.1111111111111, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI25147288, Length=251, Percent_Identity=30.6772908366534, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=30.9160305343511, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=29.6577946768061, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=260, Percent_Identity=28.8461538461538, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=276, Percent_Identity=30.0724637681159, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17565030, Length=271, Percent_Identity=31.7343173431734, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=266, Percent_Identity=28.1954887218045, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=30.5970149253731, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=29.4339622641509, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17508651, Length=252, Percent_Identity=29.7619047619048, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=29.4354838709677, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=274, Percent_Identity=28.4671532846715, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=29.3650793650794, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=252, Percent_Identity=28.968253968254, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=27.6515151515151, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=257, Percent_Identity=28.0155642023346, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=28.968253968254, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=31.8897637795276, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=256, Percent_Identity=25.390625, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=194, Percent_Identity=31.4432989690722, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=258, Percent_Identity=28.6821705426357, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6322226, Length=184, Percent_Identity=30.9782608695652, Blast_Score=66, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=33.8645418326693, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=33.4661354581673, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24639444, Length=257, Percent_Identity=30.3501945525292, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=30.952380952381, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=32.5490196078431, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28571526, Length=255, Percent_Identity=30.9803921568627, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=29.3172690763052, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24644337, Length=261, Percent_Identity=30.2681992337165, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24665243, Length=190, Percent_Identity=31.5789473684211, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221331218, Length=190, Percent_Identity=31.5789473684211, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25763; Mature: 25763

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGLRGRRALVTGGTKGIGAAIVDLLADEGAAVALCARNAAEVAAKVAALRARGVAATG
CCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCC
RAVDVADSAALRGWVAEAAEELGGLDIVVPNVSALAVGGDEAAWRSGFAVDMMGTVSAVE
CEEECCHHHHHHHHHHHHHHHHCCCEEEECCCEEEEECCCHHHHHCCCEEEHHHHHHHHH
AAMPYLERSEAGAIVVISSVSGREIDFAAGPYGAFKAALIHYAQGLAFQLAPRNIRANSV
HHHHHHHCCCCCEEEEEECCCCCEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCC
SPGNTYFAGGVWHQIETGNPALFAEALRLNPTGRMARPEEVARAAVFLASPAASFITGTN
CCCCEEEECCEEEEEECCCHHHEEHHHEECCCCCCCCHHHHHHHHHHHHCCHHHHHCCCC
LVVDGSLTRGVQF
EEEECCCCCCCCC
>Mature Secondary Structure
MDLGLRGRRALVTGGTKGIGAAIVDLLADEGAAVALCARNAAEVAAKVAALRARGVAATG
CCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCC
RAVDVADSAALRGWVAEAAEELGGLDIVVPNVSALAVGGDEAAWRSGFAVDMMGTVSAVE
CEEECCHHHHHHHHHHHHHHHHCCCEEEECCCEEEEECCCHHHHHCCCEEEHHHHHHHHH
AAMPYLERSEAGAIVVISSVSGREIDFAAGPYGAFKAALIHYAQGLAFQLAPRNIRANSV
HHHHHHHCCCCCEEEEEECCCCCEEEECCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCC
SPGNTYFAGGVWHQIETGNPALFAEALRLNPTGRMARPEEVARAAVFLASPAASFITGTN
CCCCEEEECCEEEEEECCCHHHEEHHHEECCCCCCCCHHHHHHHHHHHHCCHHHHHCCCC
LVVDGSLTRGVQF
EEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]