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The map label for this gene is frc [H]

Identifier: 170749665

GI number: 170749665

Start: 3456007

End: 3457278

Strand: Direct

Name: frc [H]

Synonym: Mrad2831_3262

Alternate gene names: 170749665

Gene position: 3456007-3457278 (Clockwise)

Preceding gene: 170749664

Following gene: 170749666

Centisome position: 56.86

GC content: 71.38

Gene sequence:

>1272_bases
ATGGGAGACCTGTACGTGCCGGATCACTCCGCCGAGACTCACTCTGCCGAGACGAACAAGGCCGGGCCGCTCGCGGGCGT
GCGGGTCGTCGACCTGACCAGCGTGATCATGGGGCCCTCGGCGACGCATATCCTCGCCGATCTCGGCGCCGACGTGATCA
AGATCGAGACGCCGGAGGGCGATTCCTTCCGGCACTACCGGCCCGCCCGGGGCCCCGGGATGGGCGGCAACTTCCTGCAC
CTCAACCGCAACAAGCGCAGCGTCCGCCTCGACCTGAAGCGGGCTGCGGCGCGGGCCGCCCTGGACCGGCTGATCGCCAC
GGCAGACGTGTTCGTCCACTCGATGCGGCCGGACGCGATCCTGCGCCTGGGCTACGGCTACGAGCGCGTGCGCGCGCTCA
AGCCCGACATCGTCTTCTGCGGCGCCTACGGGTTCGGGGCCGACGGCCCCTACGCCCACAAGGCGGCCTACGACGACCTG
ATCCAGGCGGGCTCGGGCCTCGCGGCGCTCCAGAAAACCGCCACCGGCCGGCCCGGCTACCTGCCCACCGTGCTGTGCGA
CAAGATCGCCGGCCAAGCCATCGCCTGCGCGATCCTCGCCGCCCTCTACGAGCGCCGGGCCGGCGGTGGCGGGCAGGCGG
TCGAGGTGCCGATGTTCGAGACCATGGTGGAGTTCAACTTCGTCGAGCACATGGTCGGCTACGCCTTCGAGCCGCCGCTG
GGGCCGCCGGGCTTCAACCGGGTGCTGAGCCCGAAGCGCAAGCCCTACCGCACCCGGGACGGCTACGCCTGCATCCTGCC
CTACTCGGACCGGAACTGGCGCGACTTCTTCATCCATACCGGCCGGCTCGAATTCGTGGACGATCCGCGCTTCGCGCCGC
TCGCCGTGCGGGTGGAGAACATCGAGATCCTCTACGCGCTGGTCGAGGAGGAGGCGCCGCGCAGGACCACCGCCGAGTGG
GTCGCGTTCTGCGACTCGGTGAGCATCCCGTGCATGCCGGTCCTCGGGCTGGAGGACCTGCCGGAGGACGAACACCTGAG
GGCGGTGAGCTTCTTCGGCACCGCCGAGCACCCGAGCGAGGGGACCTACCGGACCATGCGCCGGCCGGTCTCGTTCAGCG
GCAGCCGGTTCGCGATCCGCCGCCACGCCCCGCGGCACGGCGAGCACACCGCCGAGGTCCTAGCCGAGGCCGGGCTCGAC
CCGGCCGAGATCGCGGCCCTGATCGACGCGCCGGGCGAAACCCACCCCGCGCCCCTGGAGGCCGCCCGATGA

Upstream 100 bases:

>100_bases
GACGCCCTCTGGCAGGAGCGGATCGGGCGCGCGGTCTGCGCGGGCGGCGGCGCGGCCCTCTGGCCGATGCTGGTCCGGCT
CCGGGGCGGTGCCGGCTGAG

Downstream 100 bases:

>100_bases
GTGCCGAGACTGGGACCCGCGACGCGGGCGAGGACCTGCTGTTCTCCGTCGCCGAGGGGGTCGCGACCATTACGCTGAAC
CGGCCCGAGCGGAAGAACGC

Product: L-carnitine dehydratase/bile acid-inducible protein F

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MGDLYVPDHSAETHSAETNKAGPLAGVRVVDLTSVIMGPSATHILADLGADVIKIETPEGDSFRHYRPARGPGMGGNFLH
LNRNKRSVRLDLKRAAARAALDRLIATADVFVHSMRPDAILRLGYGYERVRALKPDIVFCGAYGFGADGPYAHKAAYDDL
IQAGSGLAALQKTATGRPGYLPTVLCDKIAGQAIACAILAALYERRAGGGGQAVEVPMFETMVEFNFVEHMVGYAFEPPL
GPPGFNRVLSPKRKPYRTRDGYACILPYSDRNWRDFFIHTGRLEFVDDPRFAPLAVRVENIEILYALVEEEAPRRTTAEW
VAFCDSVSIPCMPVLGLEDLPEDEHLRAVSFFGTAEHPSEGTYRTMRRPVSFSGSRFAIRRHAPRHGEHTAEVLAEAGLD
PAEIAALIDAPGETHPAPLEAAR

Sequences:

>Translated_423_residues
MGDLYVPDHSAETHSAETNKAGPLAGVRVVDLTSVIMGPSATHILADLGADVIKIETPEGDSFRHYRPARGPGMGGNFLH
LNRNKRSVRLDLKRAAARAALDRLIATADVFVHSMRPDAILRLGYGYERVRALKPDIVFCGAYGFGADGPYAHKAAYDDL
IQAGSGLAALQKTATGRPGYLPTVLCDKIAGQAIACAILAALYERRAGGGGQAVEVPMFETMVEFNFVEHMVGYAFEPPL
GPPGFNRVLSPKRKPYRTRDGYACILPYSDRNWRDFFIHTGRLEFVDDPRFAPLAVRVENIEILYALVEEEAPRRTTAEW
VAFCDSVSIPCMPVLGLEDLPEDEHLRAVSFFGTAEHPSEGTYRTMRRPVSFSGSRFAIRRHAPRHGEHTAEVLAEAGLD
PAEIAALIDAPGETHPAPLEAAR
>Mature_422_residues
GDLYVPDHSAETHSAETNKAGPLAGVRVVDLTSVIMGPSATHILADLGADVIKIETPEGDSFRHYRPARGPGMGGNFLHL
NRNKRSVRLDLKRAAARAALDRLIATADVFVHSMRPDAILRLGYGYERVRALKPDIVFCGAYGFGADGPYAHKAAYDDLI
QAGSGLAALQKTATGRPGYLPTVLCDKIAGQAIACAILAALYERRAGGGGQAVEVPMFETMVEFNFVEHMVGYAFEPPLG
PPGFNRVLSPKRKPYRTRDGYACILPYSDRNWRDFFIHTGRLEFVDDPRFAPLAVRVENIEILYALVEEEAPRRTTAEWV
AFCDSVSIPCMPVLGLEDLPEDEHLRAVSFFGTAEHPSEGTYRTMRRPVSFSGSRFAIRRHAPRHGEHTAEVLAEAGLDP
AEIAALIDAPGETHPAPLEAAR

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=387, Percent_Identity=26.0981912144703, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI300863124, Length=413, Percent_Identity=25.90799031477, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI300863126, Length=384, Percent_Identity=25.78125, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI266456254, Length=405, Percent_Identity=26.9135802469136, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI42794625, Length=405, Percent_Identity=27.1604938271605, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI266458393, Length=245, Percent_Identity=30.6122448979592, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI266458397, Length=202, Percent_Identity=31.6831683168317, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1788717, Length=408, Percent_Identity=31.8627450980392, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI87082093, Length=334, Percent_Identity=30.2395209580838, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1786222, Length=410, Percent_Identity=26.3414634146341, Blast_Score=87, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24648431, Length=398, Percent_Identity=32.1608040201005, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24585488, Length=338, Percent_Identity=26.0355029585799, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 46199; Mature: 46068

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDLYVPDHSAETHSAETNKAGPLAGVRVVDLTSVIMGPSATHILADLGADVIKIETPEG
CCCCCCCCCCCCCCCCCCCCCCCCCCEEHEEHHHHHHCCCHHHHHHHCCCCEEEEECCCC
DSFRHYRPARGPGMGGNFLHLNRNKRSVRLDLKRAAARAALDRLIATADVFVHSMRPDAI
CCCCCCCCCCCCCCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
LRLGYGYERVRALKPDIVFCGAYGFGADGPYAHKAAYDDLIQAGSGLAALQKTATGRPGY
EEECCCHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCC
LPTVLCDKIAGQAIACAILAALYERRAGGGGQAVEVPMFETMVEFNFVEHMVGYAFEPPL
CHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHCCCCCCCC
GPPGFNRVLSPKRKPYRTRDGYACILPYSDRNWRDFFIHTGRLEFVDDPRFAPLAVRVEN
CCCCCCHHCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCEEEEECCCCCCEEEEEEEC
IEILYALVEEEAPRRTTAEWVAFCDSVSIPCMPVLGLEDLPEDEHLRAVSFFGTAEHPSE
CEEEEEEHHCCCCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCCCEEEEEEECCCCCCCC
GTYRTMRRPVSFSGSRFAIRRHAPRHGEHTAEVLAEAGLDPAEIAALIDAPGETHPAPLE
CCHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCC
AAR
CCC
>Mature Secondary Structure 
GDLYVPDHSAETHSAETNKAGPLAGVRVVDLTSVIMGPSATHILADLGADVIKIETPEG
CCCCCCCCCCCCCCCCCCCCCCCCCEEHEEHHHHHHCCCHHHHHHHCCCCEEEEECCCC
DSFRHYRPARGPGMGGNFLHLNRNKRSVRLDLKRAAARAALDRLIATADVFVHSMRPDAI
CCCCCCCCCCCCCCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
LRLGYGYERVRALKPDIVFCGAYGFGADGPYAHKAAYDDLIQAGSGLAALQKTATGRPGY
EEECCCHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCC
LPTVLCDKIAGQAIACAILAALYERRAGGGGQAVEVPMFETMVEFNFVEHMVGYAFEPPL
CHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHCCCCCCCC
GPPGFNRVLSPKRKPYRTRDGYACILPYSDRNWRDFFIHTGRLEFVDDPRFAPLAVRVEN
CCCCCCHHCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCEEEEECCCCCCEEEEEEEC
IEILYALVEEEAPRRTTAEWVAFCDSVSIPCMPVLGLEDLPEDEHLRAVSFFGTAEHPSE
CEEEEEEHHCCCCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCCCEEEEEEECCCCCCCC
GTYRTMRRPVSFSGSRFAIRRHAPRHGEHTAEVLAEAGLDPAEIAALIDAPGETHPAPLE
CCHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCC
AAR
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA