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The map label for this gene is dat [H]

Identifier: 170749617

GI number: 170749617

Start: 3399123

End: 3400424

Strand: Reverse

Name: dat [H]

Synonym: Mrad2831_3214

Alternate gene names: 170749617

Gene position: 3400424-3399123 (Counterclockwise)

Preceding gene: 170749618

Following gene: 170749616

Centisome position: 55.95

GC content: 72.96

Gene sequence:

>1302_bases
ATGACCGCGTCTTCCACGTCCGCCCCGGCCGCTTCCGCCGAGGCCCTGATCGCCCGGCGCCGCGACCTCCTCGGCGCCTC
GTACCGGCTCTTCTACGAGCGGCCGGTCCACATCGTGCGCGGCGAGGATGTCTGGCTGTACGACGCCGACGGGCGCCGCT
ACCTCGACGCCTACAACAACGTGCCCTGCGTCGGCCATTGCCACCCGCGGGTGGTGGAGGCGGTGACGCGCCAGATGGCC
ACCCTCAACACCCACACCCGCTACCTGCACGAGGCGGTGCTCGACTACTCCGAGCGGCTGCTCTCCACCTATCCGGCCGC
CTTCGGCCACGTCATGTACACCTGCACGGGGTCCGAGGCGGTGGACCTCGCCCTGCGGATCGCGCGCTACCAGACCGGCG
GCACCGGTCTGGTGATCACGCGGAACGCCTATCACGGGACCACCGAGGCCACGGCGGGGATCTCCCCGTCGCTCGGCCCG
GCCGTCCCCCTCGGCCGCGATGTCTGGACGGTGCCGGCGCCGGACGCCTACCGGAATCCCGGCGTCGACGTCGGCGCGCG
GCTGGCCGAGGACGTTCGGGCGGCCTTCGCCGACATGCGCCGCCACGGCGTGCGGCCCGCGGCGTTCATCGCCGACGGCA
TCTTCTCGACGGACGGGACCCTGGCCGAGCCCGCCGGCTTCCTCCGGCCGGCCCGGGAGGCGGTGCGGGAGGCCGGCGCG
CTCTACATCGCCGACGAGGTGCAGCCGGGCTTCGGCCGGACCGGGGCAGGCATGTGGGGCTTCGCCCGCCACGGCATCGT
TCCCGACATGGCCGTGATGGGCAAGCCGATGGGCAATGGCCTGCCCATCGCGGGGGTCGCGATGCAGCCCGAGGTGGCGG
AACGGTTCGGCCGGGACGTGCGCTACTTCAACACCTTCGGCGCCAACACCGTCTCGATCGCGGCGGCCGGCGCGGTGCTC
GACATCCTGGCGGACCAGGACCTGGTGGCGAACGCCGCCGCCACCGGCCGCCTGATGCTGGAGGGGATGCGGGCGCTGAT
GGCGCGGATCCCGGCCATCGGCGACGTGCGGGGGGCGGGCCTGTTCCTCGGTCTCGACCTCGTCGCCTGCCGGGAGAGCC
GCACCCCCGACGCGGCGCTGGCCAAGCGGGTCGTCAACGCCCTGCGCGAGGAGGGTATCCTGATCAGCGCGTCCGGCCCC
CACGACAACGTGCTGAAAATCCGCCCGCCGCTGACCTTCTCCGCCGAGCACGCCGCGCTGTTCCTTGAGGTCCTGGGAAA
AACCCTGGACGGTGCGGCCTGA

Upstream 100 bases:

>100_bases
CAGCGCCGGCGTCTGGGAGCAGTTCCGGCACCTCGACGACCTGGCGCCGGAAGCGATGGATGCGGCGATCGCCGAGGCCT
GTCGTTCCTGAGGCCACGCC

Downstream 100 bases:

>100_bases
CAAGAAGAACGAAAGACCTGGCAGGAGACGACCCATGCATCCAGCGGACGTCCTGGATCCGAGTCCGGTGGCGGGACCGG
CCCTGCGCGCCGATCTGCCG

Product: class-III aminotransferase

Products: NA

Alternate protein names: Diaminobutyrate transaminase; L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase; DABA aminotransferase; DABA-AT; L-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MTASSTSAPAASAEALIARRRDLLGASYRLFYERPVHIVRGEDVWLYDADGRRYLDAYNNVPCVGHCHPRVVEAVTRQMA
TLNTHTRYLHEAVLDYSERLLSTYPAAFGHVMYTCTGSEAVDLALRIARYQTGGTGLVITRNAYHGTTEATAGISPSLGP
AVPLGRDVWTVPAPDAYRNPGVDVGARLAEDVRAAFADMRRHGVRPAAFIADGIFSTDGTLAEPAGFLRPAREAVREAGA
LYIADEVQPGFGRTGAGMWGFARHGIVPDMAVMGKPMGNGLPIAGVAMQPEVAERFGRDVRYFNTFGANTVSIAAAGAVL
DILADQDLVANAAATGRLMLEGMRALMARIPAIGDVRGAGLFLGLDLVACRESRTPDAALAKRVVNALREEGILISASGP
HDNVLKIRPPLTFSAEHAALFLEVLGKTLDGAA

Sequences:

>Translated_433_residues
MTASSTSAPAASAEALIARRRDLLGASYRLFYERPVHIVRGEDVWLYDADGRRYLDAYNNVPCVGHCHPRVVEAVTRQMA
TLNTHTRYLHEAVLDYSERLLSTYPAAFGHVMYTCTGSEAVDLALRIARYQTGGTGLVITRNAYHGTTEATAGISPSLGP
AVPLGRDVWTVPAPDAYRNPGVDVGARLAEDVRAAFADMRRHGVRPAAFIADGIFSTDGTLAEPAGFLRPAREAVREAGA
LYIADEVQPGFGRTGAGMWGFARHGIVPDMAVMGKPMGNGLPIAGVAMQPEVAERFGRDVRYFNTFGANTVSIAAAGAVL
DILADQDLVANAAATGRLMLEGMRALMARIPAIGDVRGAGLFLGLDLVACRESRTPDAALAKRVVNALREEGILISASGP
HDNVLKIRPPLTFSAEHAALFLEVLGKTLDGAA
>Mature_432_residues
TASSTSAPAASAEALIARRRDLLGASYRLFYERPVHIVRGEDVWLYDADGRRYLDAYNNVPCVGHCHPRVVEAVTRQMAT
LNTHTRYLHEAVLDYSERLLSTYPAAFGHVMYTCTGSEAVDLALRIARYQTGGTGLVITRNAYHGTTEATAGISPSLGPA
VPLGRDVWTVPAPDAYRNPGVDVGARLAEDVRAAFADMRRHGVRPAAFIADGIFSTDGTLAEPAGFLRPAREAVREAGAL
YIADEVQPGFGRTGAGMWGFARHGIVPDMAVMGKPMGNGLPIAGVAMQPEVAERFGRDVRYFNTFGANTVSIAAAGAVLD
ILADQDLVANAAATGRLMLEGMRALMARIPAIGDVRGAGLFLGLDLVACRESRTPDAALAKRVVNALREEGILISASGPH
DNVLKIRPPLTFSAEHAALFLEVLGKTLDGAA

Specific function: 4-aminobutyrate (GABA) degradation. [C]

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=423, Percent_Identity=41.1347517730496, Blast_Score=333, Evalue=2e-91,
Organism=Homo sapiens, GI226442705, Length=423, Percent_Identity=39.7163120567376, Blast_Score=310, Evalue=1e-84,
Organism=Homo sapiens, GI24119277, Length=412, Percent_Identity=39.8058252427184, Blast_Score=301, Evalue=6e-82,
Organism=Homo sapiens, GI226442709, Length=378, Percent_Identity=41.5343915343915, Blast_Score=297, Evalue=1e-80,
Organism=Homo sapiens, GI13994255, Length=428, Percent_Identity=31.0747663551402, Blast_Score=226, Evalue=5e-59,
Organism=Homo sapiens, GI4557809, Length=425, Percent_Identity=25.8823529411765, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI188536080, Length=433, Percent_Identity=24.9422632794457, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI38679950, Length=433, Percent_Identity=24.9422632794457, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI38679946, Length=433, Percent_Identity=24.9422632794457, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI284507298, Length=226, Percent_Identity=27.4336283185841, Blast_Score=82, Evalue=7e-16,
Organism=Escherichia coli, GI1789016, Length=413, Percent_Identity=29.5399515738499, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI145693181, Length=397, Percent_Identity=28.2115869017632, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788044, Length=392, Percent_Identity=28.3163265306122, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1789759, Length=383, Percent_Identity=26.1096605744125, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787560, Length=387, Percent_Identity=27.6485788113695, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786349, Length=389, Percent_Identity=25.706940874036, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71992977, Length=451, Percent_Identity=36.8070953436807, Blast_Score=302, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI32564660, Length=438, Percent_Identity=33.3333333333333, Blast_Score=256, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI25144271, Length=437, Percent_Identity=26.7734553775744, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71992985, Length=148, Percent_Identity=38.5135135135135, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI25144274, Length=224, Percent_Identity=28.125, Blast_Score=92, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6323470, Length=424, Percent_Identity=27.122641509434, Blast_Score=120, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6324432, Length=406, Percent_Identity=26.1083743842365, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI21356575, Length=426, Percent_Identity=39.906103286385, Blast_Score=307, Evalue=8e-84,
Organism=Drosophila melanogaster, GI161085790, Length=442, Percent_Identity=35.5203619909502, Blast_Score=272, Evalue=4e-73,
Organism=Drosophila melanogaster, GI28574759, Length=442, Percent_Identity=34.841628959276, Blast_Score=268, Evalue=6e-72,
Organism=Drosophila melanogaster, GI21357415, Length=447, Percent_Identity=26.1744966442953, Blast_Score=126, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 46106; Mature: 45975

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASSTSAPAASAEALIARRRDLLGASYRLFYERPVHIVRGEDVWLYDADGRRYLDAYNN
CCCCCCCCCCHHHHHHHHHHHHHHCCHHEEEEECCEEEEECCEEEEECCCCCCHHHHCCC
VPCVGHCHPRVVEAVTRQMATLNTHTRYLHEAVLDYSERLLSTYPAAFGHVMYTCTGSEA
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEEEECCCHH
VDLALRIARYQTGGTGLVITRNAYHGTTEATAGISPSLGPAVPLGRDVWTVPAPDAYRNP
HHHHHHHHHEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCC
GVDVGARLAEDVRAAFADMRRHGVRPAAFIADGIFSTDGTLAEPAGFLRPAREAVREAGA
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
LYIADEVQPGFGRTGAGMWGFARHGIVPDMAVMGKPMGNGLPIAGVAMQPEVAERFGRDV
EEEEECCCCCCCCCCCCCCHHHHCCCCCCHHHHCCCCCCCCCCCCEECCCHHHHHCCCCE
RYFNTFGANTVSIAAAGAVLDILADQDLVANAAATGRLMLEGMRALMARIPAIGDVRGAG
EEHHCCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LFLGLDLVACRESRTPDAALAKRVVNALREEGILISASGPHDNVLKIRPPLTFSAEHAAL
EEEHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCEEEECCCCCCCHHHHHH
FLEVLGKTLDGAA
HHHHHHHHCCCCC
>Mature Secondary Structure 
TASSTSAPAASAEALIARRRDLLGASYRLFYERPVHIVRGEDVWLYDADGRRYLDAYNN
CCCCCCCCCHHHHHHHHHHHHHHCCHHEEEEECCEEEEECCEEEEECCCCCCHHHHCCC
VPCVGHCHPRVVEAVTRQMATLNTHTRYLHEAVLDYSERLLSTYPAAFGHVMYTCTGSEA
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEEEECCCHH
VDLALRIARYQTGGTGLVITRNAYHGTTEATAGISPSLGPAVPLGRDVWTVPAPDAYRNP
HHHHHHHHHEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCC
GVDVGARLAEDVRAAFADMRRHGVRPAAFIADGIFSTDGTLAEPAGFLRPAREAVREAGA
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
LYIADEVQPGFGRTGAGMWGFARHGIVPDMAVMGKPMGNGLPIAGVAMQPEVAERFGRDV
EEEEECCCCCCCCCCCCCCHHHHCCCCCCHHHHCCCCCCCCCCCCEECCCHHHHHCCCCE
RYFNTFGANTVSIAAAGAVLDILADQDLVANAAATGRLMLEGMRALMARIPAIGDVRGAG
EEHHCCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LFLGLDLVACRESRTPDAALAKRVVNALREEGILISASGPHDNVLKIRPPLTFSAEHAAL
EEEHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCEEEECCCCCCCHHHHHH
FLEVLGKTLDGAA
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9514614 [H]