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The map label for this gene is yfhR [C]

Identifier: 170749589

GI number: 170749589

Start: 3361276

End: 3362178

Strand: Reverse

Name: yfhR [C]

Synonym: Mrad2831_3184

Alternate gene names: 170749589

Gene position: 3362178-3361276 (Counterclockwise)

Preceding gene: 170749592

Following gene: 170749588

Centisome position: 55.32

GC content: 75.86

Gene sequence:

>903_bases
ATGCTGACCCGTCGCCCTAGAAAACACATCCCGGAAACCGTTCGTCCGAACGCCCTCGCTCTCCCAGACCGCATGCGCCT
CCTCGCCGGCCTCCTGCTCGCCGCGCTCCTGCTCTGCGGCCTGGCCTGCGCCGCGCTCGCGCTCGGGCAGCGGCGGTTCC
TCTACCCGGGCGCCTTCGGTCCGCAGAACCCGTGGACGATCCCGCCCGGCCTCGCGACGATCACGGTCGCGACCCCCGAC
GGCGAGAGCCTGCACGGTCTGTGGCGGCCGCCGCGGCCGGGCTGCGGCGTCGTCGTCAGCTTCCACGGCAACGGGTCGCG
CCCCGAGCCGCACGCGGCGCGATTCGCCGCGGGGCCCTGGCGGGCGGGCGGCTGGGGCGTGCTCTCCGTGGCCTATCGCG
GCTACCCCGGCTCGACCGGGAGTCCGAGCGAGGACGGGCTGATCCGCGACGGGCTGGCGGCCGTCGAGGCCGCGCGGGCG
CGGGCGCCCGGCGCGCCGATCCTGCTCCACGGCCATTCCCTCGGGGCTGCCGTGGCCGTGGCCGTCGCCGAGCGGGTGCC
GGCGATCGGGCTGTACCTGGAGGCGCCCTTCGACTCGATGACCCACACCGTGCGGCTGCATGTCCCGCTAGCCCCGATCT
GGCTCCTGCGCGACACGTACCGCTCGGACCTGCGCATCCGCGGTGGGACGGCGCCCGTGCTGATCGTGCAGGGCCGCGAC
GACACGGTCGTGCCGGCCAAGCTGGCGCGGAACCTCGCCGAGGCGGCCGGCCCCCGGGCCCGGATCGACGTGATCCCGGG
GGACCACGTCTCCATCCTCGGGATCCGGGATCGCGAGGCCGAGGCGCTGTTCGGGTCGCGCGTCGGTCCGGCCTGCCCGC
AGCCGGCGGACCAGCAGGGGTAG

Upstream 100 bases:

>100_bases
CGGATCAGGTTCAAGGGTCAGGGCAGCGTGCCCAATCTCAGCCCTCTGCAGGGCCCCCCTCGGAACGGTTCCAGATTCGG
GCTCGCGGACGGCTTTGTCA

Downstream 100 bases:

>100_bases
GAGAGGGAGGCTCGCGTGGTCGGACGGCGCTCGCAGCGCTGGAGCGCCGAGGATCCGGACGCGCCGGGCGTTCTGGGCCC
GCCGGACCCGGTCTGTCCCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MLTRRPRKHIPETVRPNALALPDRMRLLAGLLLAALLLCGLACAALALGQRRFLYPGAFGPQNPWTIPPGLATITVATPD
GESLHGLWRPPRPGCGVVVSFHGNGSRPEPHAARFAAGPWRAGGWGVLSVAYRGYPGSTGSPSEDGLIRDGLAAVEAARA
RAPGAPILLHGHSLGAAVAVAVAERVPAIGLYLEAPFDSMTHTVRLHVPLAPIWLLRDTYRSDLRIRGGTAPVLIVQGRD
DTVVPAKLARNLAEAAGPRARIDVIPGDHVSILGIRDREAEALFGSRVGPACPQPADQQG

Sequences:

>Translated_300_residues
MLTRRPRKHIPETVRPNALALPDRMRLLAGLLLAALLLCGLACAALALGQRRFLYPGAFGPQNPWTIPPGLATITVATPD
GESLHGLWRPPRPGCGVVVSFHGNGSRPEPHAARFAAGPWRAGGWGVLSVAYRGYPGSTGSPSEDGLIRDGLAAVEAARA
RAPGAPILLHGHSLGAAVAVAVAERVPAIGLYLEAPFDSMTHTVRLHVPLAPIWLLRDTYRSDLRIRGGTAPVLIVQGRD
DTVVPAKLARNLAEAAGPRARIDVIPGDHVSILGIRDREAEALFGSRVGPACPQPADQQG
>Mature_300_residues
MLTRRPRKHIPETVRPNALALPDRMRLLAGLLLAALLLCGLACAALALGQRRFLYPGAFGPQNPWTIPPGLATITVATPD
GESLHGLWRPPRPGCGVVVSFHGNGSRPEPHAARFAAGPWRAGGWGVLSVAYRGYPGSTGSPSEDGLIRDGLAAVEAARA
RAPGAPILLHGHSLGAAVAVAVAERVPAIGLYLEAPFDSMTHTVRLHVPLAPIWLLRDTYRSDLRIRGGTAPVLIVQGRD
DTVVPAKLARNLAEAAGPRARIDVIPGDHVSILGIRDREAEALFGSRVGPACPQPADQQG

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To S.pombe bem46 and yeast YNL320w [H]

Homologues:

Organism=Homo sapiens, GI32451492, Length=186, Percent_Identity=33.3333333333333, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI32528310, Length=186, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI109689718, Length=183, Percent_Identity=30.0546448087432, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI24308097, Length=183, Percent_Identity=30.0546448087432, Blast_Score=82, Evalue=7e-16,
Organism=Escherichia coli, GI226510965, Length=273, Percent_Identity=26.3736263736264, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17566318, Length=231, Percent_Identity=26.4069264069264, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24655464, Length=204, Percent_Identity=29.9019607843137, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24655467, Length=204, Percent_Identity=29.9019607843137, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI17137566, Length=203, Percent_Identity=30.0492610837438, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002925 [H]

Pfam domain/function: PF01738 DLH [H]

EC number: NA

Molecular weight: Translated: 31606; Mature: 31606

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTRRPRKHIPETVRPNALALPDRMRLLAGLLLAALLLCGLACAALALGQRRFLYPGAFG
CCCCCCHHHCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCC
PQNPWTIPPGLATITVATPDGESLHGLWRPPRPGCGVVVSFHGNGSRPEPHAARFAAGPW
CCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHCCCCCC
RAGGWGVLSVAYRGYPGSTGSPSEDGLIRDGLAAVEAARARAPGAPILLHGHSLGAAVAV
CCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHH
AVAERVPAIGLYLEAPFDSMTHTVRLHVPLAPIWLLRDTYRSDLRIRGGTAPVLIVQGRD
HHHHHCCEEEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHCCEEEECCCCCEEEEECCC
DTVVPAKLARNLAEAAGPRARIDVIPGDHVSILGIRDREAEALFGSRVGPACPQPADQQG
CCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLTRRPRKHIPETVRPNALALPDRMRLLAGLLLAALLLCGLACAALALGQRRFLYPGAFG
CCCCCCHHHCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCC
PQNPWTIPPGLATITVATPDGESLHGLWRPPRPGCGVVVSFHGNGSRPEPHAARFAAGPW
CCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHCCCCCC
RAGGWGVLSVAYRGYPGSTGSPSEDGLIRDGLAAVEAARARAPGAPILLHGHSLGAAVAV
CCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHH
AVAERVPAIGLYLEAPFDSMTHTVRLHVPLAPIWLLRDTYRSDLRIRGGTAPVLIVQGRD
HHHHHCCEEEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHCCEEEECCCCCEEEEECCC
DTVVPAKLARNLAEAAGPRARIDVIPGDHVSILGIRDREAEALFGSRVGPACPQPADQQG
CCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]