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The map label for this gene is chvG [H]

Identifier: 170749493

GI number: 170749493

Start: 3263761

End: 3265566

Strand: Reverse

Name: chvG [H]

Synonym: Mrad2831_3088

Alternate gene names: 170749493

Gene position: 3265566-3263761 (Counterclockwise)

Preceding gene: 170749494

Following gene: 170749492

Centisome position: 53.73

GC content: 71.21

Gene sequence:

>1806_bases
GTGACCGTCCGTACTCAGACCCAGACCGAGGATGCCGCGCCCCGCACCTCCCTGGCCCAGACCCTGTCCCGACCGCTCGG
CTGGCCCCGCGCCGTGTGGGAGGCGATCGGCCAGCGCGCCTCGTCGAGCCTGACGCGCCGCATCGTCGTCCTCAACCTCG
TCGGGTTGATCGCGCTCCTCGTCGGATTCCTGTACCTCAATCAGTTCCGCCAGGGCCTGATCCAGGCCCGGATCCAGAGT
CTCGCCATCCAGGGCGAGATCATCGCTGGGGCGATCGCCGCCTCGGCGTCTGTGGACACCGACACGATCCGCATCGACCC
CGACAAGCTGCTGCAGCAGCAGGCCGGCGAGGCGGCGGAGGAGGAATCGCAGCCGCTCGCCTTCTCGCTCAACCCCGAGA
AGGTGGCGCCGCTCCTGTCGCGGCTCGTGACGCCGACGGGCAACCGCGCCCGTGTCTACGACCAGGAGGGCGGCCTCCTG
TTCGACACCCGCACCCTGTTCAAGCGCGGCGATGCCAGCCGGCCCGACCCGTTGGAGCCGAAGCCCCACAAGCCCGGGAT
GCTCGAATCCGCCTTCGAGGCGATCCAGTCCAAGCTCGGCGGCCTGTTCCGCAGCCGGACCGAGACCGCCGAGGAGACCG
GGCCGGTGAACGGCCACTCGCTGCGCGAGGTCCAGGCGGCGCTCGGTGGCAATCGCGGCAGCCTCGTCCGCCGGAACAAG
CTCGGCGAGACCACCGTCTCGGTGGCGGTGCCGATTCACCGGGCCGGCTCGGTCCGCGGCGCCCTGCTGATCTCGACCCA
GGGCGACGCGATCGACCGTGTCATCGCCTCGGAGCGGTTCGGCCTGCTCCAGGTGTTCCTCGTCGCGTCGGCGGTGATGG
TGGTGCTGTCGTTCCTGCTGGCGGGCGCGATCGCGGGACCGGTGCGCCGCCTCGCGGAGGCCGCCGAGAAGGTCCGCATG
GGCATCAAGACCCGCGAGGAGATCCCGGACTTCACCGAGCGCACCGACGAGATCGGCCACCTGTCCGGCGCCCTCCGGGA
CATGACACAGGCCCTCTACCGGCGGATCGACGCCATCGAGAGCTTCGCGGCGGATGTCAGCCACGAGCTGAAGAACCCGC
TGACCTCGCTTCGCAGCGCGGTGGAGACGCTGCCGCTCGCCCGGAACGACGAGTCCCGCGGCCGGCTGATGGCGATCATC
CAGCACGACGTGAAGCGCCTCGACCGCCTGATCAGCGACATCGCCGACGCCTCGCGCCTCGACGCGGAGCTGGCGCGCGC
CGAGGCGCGCCGGGTCGATCTCCGGCGGCTGCTCACCACGGTCGTGTCGGTCGCCAACGAGCGGCGGCGCCCCAAGGATT
GCCTGATCCAGCTCGACGTCGAGGCGACGGGCTCCGAGCAGGACGCGCCGTTCACGATCATCGGCCACGACAGCCGGCTC
GGGCAGGTGGTCAACAACCTGCTCGACAATGCCAGGTCATTCTCACCGACCGACGCGAAGGTCCGGGTCGTGCTGCGCCG
GGTGCGCGGCGAGGTCGAGATGATCTGCGAGGACGAGGGTCCGGGTATCCCGGAGCACGCGCTGGAGCGGATCTTCGAGC
GCTTCTACACCGACCGGCCGGAGCAGGGCTTCGGCCAGAACTCGGGCCTCGGCCTTTCGATCTCCCGCCAGATCGTCCAG
GCCCACCGCGGCACGATCCGCGCCGAGAACCGGCCGGGCGCTCCCGACGAGGACGGCGAGCCGACGGTGCGCGGCGCCCG
GTTCGTCGTGCGCCTGCCGGCGGCGCCGCGGCAGCTCCACGCCTGA

Upstream 100 bases:

>100_bases
GGAAGAAGTTCAAGGTCACAGACCAGAGCTTCGACATGATCGAGACGCTCTACGGCGTCGGCTACCGATTCAAGGAGGCG
TGATCTCCAGGATCCGCCCC

Downstream 100 bases:

>100_bases
TGGTCACCCTGCACGGCGCCTGCATCGCGCTGCGCGCGGCCGGCATCCTGATTCGCGGTCCCTCGGGCGCGGGCAAGTCC
AGTCTCGCGCTCCTGCTCGC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Histidine kinase sensory protein ExoS [H]

Number of amino acids: Translated: 601; Mature: 600

Protein sequence:

>601_residues
MTVRTQTQTEDAAPRTSLAQTLSRPLGWPRAVWEAIGQRASSSLTRRIVVLNLVGLIALLVGFLYLNQFRQGLIQARIQS
LAIQGEIIAGAIAASASVDTDTIRIDPDKLLQQQAGEAAEEESQPLAFSLNPEKVAPLLSRLVTPTGNRARVYDQEGGLL
FDTRTLFKRGDASRPDPLEPKPHKPGMLESAFEAIQSKLGGLFRSRTETAEETGPVNGHSLREVQAALGGNRGSLVRRNK
LGETTVSVAVPIHRAGSVRGALLISTQGDAIDRVIASERFGLLQVFLVASAVMVVLSFLLAGAIAGPVRRLAEAAEKVRM
GIKTREEIPDFTERTDEIGHLSGALRDMTQALYRRIDAIESFAADVSHELKNPLTSLRSAVETLPLARNDESRGRLMAII
QHDVKRLDRLISDIADASRLDAELARAEARRVDLRRLLTTVVSVANERRRPKDCLIQLDVEATGSEQDAPFTIIGHDSRL
GQVVNNLLDNARSFSPTDAKVRVVLRRVRGEVEMICEDEGPGIPEHALERIFERFYTDRPEQGFGQNSGLGLSISRQIVQ
AHRGTIRAENRPGAPDEDGEPTVRGARFVVRLPAAPRQLHA

Sequences:

>Translated_601_residues
MTVRTQTQTEDAAPRTSLAQTLSRPLGWPRAVWEAIGQRASSSLTRRIVVLNLVGLIALLVGFLYLNQFRQGLIQARIQS
LAIQGEIIAGAIAASASVDTDTIRIDPDKLLQQQAGEAAEEESQPLAFSLNPEKVAPLLSRLVTPTGNRARVYDQEGGLL
FDTRTLFKRGDASRPDPLEPKPHKPGMLESAFEAIQSKLGGLFRSRTETAEETGPVNGHSLREVQAALGGNRGSLVRRNK
LGETTVSVAVPIHRAGSVRGALLISTQGDAIDRVIASERFGLLQVFLVASAVMVVLSFLLAGAIAGPVRRLAEAAEKVRM
GIKTREEIPDFTERTDEIGHLSGALRDMTQALYRRIDAIESFAADVSHELKNPLTSLRSAVETLPLARNDESRGRLMAII
QHDVKRLDRLISDIADASRLDAELARAEARRVDLRRLLTTVVSVANERRRPKDCLIQLDVEATGSEQDAPFTIIGHDSRL
GQVVNNLLDNARSFSPTDAKVRVVLRRVRGEVEMICEDEGPGIPEHALERIFERFYTDRPEQGFGQNSGLGLSISRQIVQ
AHRGTIRAENRPGAPDEDGEPTVRGARFVVRLPAAPRQLHA
>Mature_600_residues
TVRTQTQTEDAAPRTSLAQTLSRPLGWPRAVWEAIGQRASSSLTRRIVVLNLVGLIALLVGFLYLNQFRQGLIQARIQSL
AIQGEIIAGAIAASASVDTDTIRIDPDKLLQQQAGEAAEEESQPLAFSLNPEKVAPLLSRLVTPTGNRARVYDQEGGLLF
DTRTLFKRGDASRPDPLEPKPHKPGMLESAFEAIQSKLGGLFRSRTETAEETGPVNGHSLREVQAALGGNRGSLVRRNKL
GETTVSVAVPIHRAGSVRGALLISTQGDAIDRVIASERFGLLQVFLVASAVMVVLSFLLAGAIAGPVRRLAEAAEKVRMG
IKTREEIPDFTERTDEIGHLSGALRDMTQALYRRIDAIESFAADVSHELKNPLTSLRSAVETLPLARNDESRGRLMAIIQ
HDVKRLDRLISDIADASRLDAELARAEARRVDLRRLLTTVVSVANERRRPKDCLIQLDVEATGSEQDAPFTIIGHDSRLG
QVVNNLLDNARSFSPTDAKVRVVLRRVRGEVEMICEDEGPGIPEHALERIFERFYTDRPEQGFGQNSGLGLSISRQIVQA
HRGTIRAENRPGAPDEDGEPTVRGARFVVRLPAAPRQLHA

Specific function: Member of a two-component regulatory system ChvG(ExoS)/ChvI involved in regulating the production of succinoglycan. Activates ChvI by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=279, Percent_Identity=28.673835125448, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790861, Length=439, Percent_Identity=25.7403189066059, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI145693157, Length=260, Percent_Identity=28.4615384615385, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1790346, Length=292, Percent_Identity=26.3698630136986, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1786783, Length=330, Percent_Identity=24.5454545454545, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786600, Length=253, Percent_Identity=28.4584980237154, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1789403, Length=292, Percent_Identity=29.7945205479452, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788549, Length=256, Percent_Identity=26.953125, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786912, Length=237, Percent_Identity=29.957805907173, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87082128, Length=353, Percent_Identity=26.3456090651558, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790551, Length=240, Percent_Identity=29.1666666666667, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1789149, Length=224, Percent_Identity=27.6785714285714, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787374, Length=371, Percent_Identity=27.2237196765499, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI48994928, Length=253, Percent_Identity=24.5059288537549, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI87081816, Length=242, Percent_Identity=28.9256198347107, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790436, Length=246, Percent_Identity=26.0162601626016, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65751; Mature: 65620

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN ; PS00172 XYLOSE_ISOMERASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRTQTQTEDAAPRTSLAQTLSRPLGWPRAVWEAIGQRASSSLTRRIVVLNLVGLIALL
CCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGFLYLNQFRQGLIQARIQSLAIQGEIIAGAIAASASVDTDTIRIDPDKLLQQQAGEAAE
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEECHHHHHHHHHCCHHH
EESQPLAFSLNPEKVAPLLSRLVTPTGNRARVYDQEGGLLFDTRTLFKRGDASRPDPLEP
HCCCCEEEECCHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEHHHHHHCCCCCCCCCCCC
KPHKPGMLESAFEAIQSKLGGLFRSRTETAEETGPVNGHSLREVQAALGGNRGSLVRRNK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHCC
LGETTVSVAVPIHRAGSVRGALLISTQGDAIDRVIASERFGLLQVFLVASAVMVVLSFLL
CCCCEEEEEEEHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGAIAGPVRRLAEAAEKVRMGIKTREEIPDFTERTDEIGHLSGALRDMTQALYRRIDAIE
HHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFAADVSHELKNPLTSLRSAVETLPLARNDESRGRLMAIIQHDVKRLDRLISDIADASRL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DAELARAEARRVDLRRLLTTVVSVANERRRPKDCLIQLDVEATGSEQDAPFTIIGHDSRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEEECCHHH
GQVVNNLLDNARSFSPTDAKVRVVLRRVRGEVEMICEDEGPGIPEHALERIFERFYTDRP
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCC
EQGFGQNSGLGLSISRQIVQAHRGTIRAENRPGAPDEDGEPTVRGARFVVRLPAAPRQLH
CCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCCCHHCC
A
C
>Mature Secondary Structure 
TVRTQTQTEDAAPRTSLAQTLSRPLGWPRAVWEAIGQRASSSLTRRIVVLNLVGLIALL
CCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGFLYLNQFRQGLIQARIQSLAIQGEIIAGAIAASASVDTDTIRIDPDKLLQQQAGEAAE
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEECHHHHHHHHHCCHHH
EESQPLAFSLNPEKVAPLLSRLVTPTGNRARVYDQEGGLLFDTRTLFKRGDASRPDPLEP
HCCCCEEEECCHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEHHHHHHCCCCCCCCCCCC
KPHKPGMLESAFEAIQSKLGGLFRSRTETAEETGPVNGHSLREVQAALGGNRGSLVRRNK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHCC
LGETTVSVAVPIHRAGSVRGALLISTQGDAIDRVIASERFGLLQVFLVASAVMVVLSFLL
CCCCEEEEEEEHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGAIAGPVRRLAEAAEKVRMGIKTREEIPDFTERTDEIGHLSGALRDMTQALYRRIDAIE
HHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFAADVSHELKNPLTSLRSAVETLPLARNDESRGRLMAIIQHDVKRLDRLISDIADASRL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DAELARAEARRVDLRRLLTTVVSVANERRRPKDCLIQLDVEATGSEQDAPFTIIGHDSRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEEECCHHH
GQVVNNLLDNARSFSPTDAKVRVVLRRVRGEVEMICEDEGPGIPEHALERIFERFYTDRP
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCC
EQGFGQNSGLGLSISRQIVQAHRGTIRAENRPGAPDEDGEPTVRGARFVVRLPAAPRQLH
CCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCCCHHCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9422587; 11481430; 7559334 [H]