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The map label for this gene is atoS [C]

Identifier: 170749452

GI number: 170749452

Start: 3212458

End: 3214902

Strand: Reverse

Name: atoS [C]

Synonym: Mrad2831_3047

Alternate gene names: 170749452

Gene position: 3214902-3212458 (Counterclockwise)

Preceding gene: 170749454

Following gene: 170749450

Centisome position: 52.9

GC content: 71.53

Gene sequence:

>2445_bases
GTGGAGATCCGCGCCCGTGACTGGGCGGAGACGCCGCTCGGGCCGCCCGACGGGTGGCCGTCGGCCCTGCGCAGCGCGCT
CGGACTGATGTTGTCCTGCCCCACCGCGATGTTCCTGGCCTGGGGACCGGACCTGCTCTGCTTCTACAACGACGCCTACC
GGCCGGTCCTCGGCTACCGCCTCGCCACGGCCCTCGGTCGTCCCTTCCGCGAGGTCTGGGCCAGCATCTGGGACGAGATC
GCACCCCTGGTGTCTGCGACCCTCGCGGGCGAGAGCCAGACCCTGACCGACGTCATGCTCGACCTGTCGCGGGACGGCCG
GTCCGAGCAGGGCTGGTGGTCCTTCACCTACTCGCCGGTGCTGGACGATGCCGGAGCGATCAGCGGCCTGTTCTGCGTCA
CCGCCGAGACAACGGCGCGCGTCCTCGGCGAGGCGCGGCTGCGCGAGAGCGAGGATCACTTCCGCCACACGGTCGAACTC
AACCCGCAGGTGCCGTGGACCTGCGACCCGCAGGGCAACATCACCTCCTACTCCAAGCGCTGGCTCGACCTGACGGGACA
GGCGCCCGGCGAGCCGGACGGCACGGGCTGGACCAGGGCGCTGCACCCGGATGATCTGCCGTGGACCATCACGGTGTTCA
CGCAATGCCTCGCTTCGGGCGAGACGGTCGATGTCGATTACCGCATCCGCGTCGCGCGGACCGGGACTTACCGGTGGATG
CGCGCCCGCGCGCAGCCGCGCCGGGCCGAGGACGGTGCCATCGTCCGCTGGTACGGCGTGGTCGAGGATATCCACGACCG
CAAGCTCGCCGAGGACCGGCTGCGCGAGATGAACGCCACCCTGGAGCGGCGCGTCGCGGAGGCCCTCGCTCAGCGCAAGC
TCTGGGCGGACGTGTTCGAGACCACCGACGCGCTCGTGGGCGCGCTGGATACCGAGTACCGGTTCCTCGCCGTGAACGCG
GCTTACGCTGACGAGTTCGAGGCGATTTACGGCCTGCGCCCGGCCGTGGGGGCCAATCTGCTGGATCTGCTGTCCGGCTA
TCCCGAGCAGCGGGCCGCCGCGCAGGCGGTCTGGTCACGCGCCCTCGCGGGCGAGGAGTTCACCGTCGCGGAGGCCTTCG
GCGATCCCGGCCTCAAGCGGCCCTCTTACGAGCTGAAGTTCACGACGCTGCGCGACGCGCGCGGTCGACGGATCGGCGCC
TTCCAGTACGCCCAGGACATCACCGAGCGCCTGCGCCACCAGGAGCAGCTCGCGCGCGCCGAGGAGGCGCTGCGCCACGC
GCAGCGGATGGAGGCGGTGGGCCAGCTCACCGGCGGCGTCGCGCACGACTTCAACAACCTGCTGACCATCATCCGCTCGT
CCGTCGAGTTCCTGCGCCGGCCGAATCTCGCCGAGGAGCGCCGCACCCGTTACCTGGAGGCGGTCTCCGACACGGTCGAC
CGCGCCGCGCGGCTGACGAACCAGCTCCTGGCCTTCGCCCGTCGCCAGCCGCTCGCGCCCGAAGTCTTCGATGTCGGGGC
GCGGCTGGGCGAGATGGCCGACATGCTGAACGCCGTGACGGGCGGGCGCGTCCGGATCGTGACGGAGATCTCCGACGCGC
GCTGCCACGTGCGGGCCGACCCGAGCCAGTTCGAGACGGCTTTGGTCAACCTCGCAATGAATGCCCGCGACGCCATGGAG
GGCGAGGGCACGCTGACGCTCAGGCTCACCTGCGGCGCCGCCCTGCCGCCGATCCGCGGCCATGCCGGCGCACCCGGACC
GTTCGCCGCCGTCGCGGTGACGGACGAGGGGCCTGGCGTGGCGCCGGATCTGCTGGGACGGATCTTCGAGCCCTTCTTCA
CCACCAAGGCCGTCGGCAAGGGCACGGGGCTCGGCCTCTCACAGGTGATCGGCTTCACCAAGCAGTCGGGCGGCGACGTC
GAGGTCGTGAGCCATGTCGGTCGCGGGGCGACCTTCACCCTCTACTTGCCGGAGGTCGACCCGCCGCCCGCGGCGGCGGA
CGACGGGGCCGTCATGGACGCGCCGGCAGGCGAGGACCGCGCGCTCTGCGTGCTGGTCGTGGAGGACAATCTCGAGGTCG
GGCGCTTCTGCACGCAGCTCCTGGAAGATCTCGGCCACGCGACCGTCTGGGCCCACAACGCCGAGGCCGCGCTCGCCGAG
ATGGAGAAGGTGCCGTTCCGGTTCGACGCCGTCTTCTCGGACGTGGTGATGCCCGGGATGGGCGGCGTCGAGCTCGCGCG
CCGGCTGCGCGCCGACCACCCCGCGCTGCCGGTCATTCTGACCACCGGCTACAGCGACGCGCTCGCGCGGGACGACGCGC
ACGGATTCGAGCTCGTGCGCAAACCTTACTCGGCCGAGCAGGTCGCGCGGGCGCTGCGCGACGTCCTGGCCCGGCACCGT
CCAGGGTCGATCGACCGGTCCGGGGTGCAAGATCGCGCCGGGTAA

Upstream 100 bases:

>100_bases
ACCGGGCGGAGCGCGCGCGGTCACCGAGACGTCCCGCTGGCGGCACGGTTCCGTCGTGGCTGATCCGTTCAGGTTCCTGC
CGCCCGGCGGTCTGACGGGG

Downstream 100 bases:

>100_bases
GCGCGTCTCAAACGTCCTCCCCCTTCGCGAAGGCCCGCAGCGAGACGCGCGCGACTTCCCGCAGCGCCTCGCGGTCGGCG
CCCGAGGAGGCCAGCACGCC

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 814; Mature: 814

Protein sequence:

>814_residues
MEIRARDWAETPLGPPDGWPSALRSALGLMLSCPTAMFLAWGPDLLCFYNDAYRPVLGYRLATALGRPFREVWASIWDEI
APLVSATLAGESQTLTDVMLDLSRDGRSEQGWWSFTYSPVLDDAGAISGLFCVTAETTARVLGEARLRESEDHFRHTVEL
NPQVPWTCDPQGNITSYSKRWLDLTGQAPGEPDGTGWTRALHPDDLPWTITVFTQCLASGETVDVDYRIRVARTGTYRWM
RARAQPRRAEDGAIVRWYGVVEDIHDRKLAEDRLREMNATLERRVAEALAQRKLWADVFETTDALVGALDTEYRFLAVNA
AYADEFEAIYGLRPAVGANLLDLLSGYPEQRAAAQAVWSRALAGEEFTVAEAFGDPGLKRPSYELKFTTLRDARGRRIGA
FQYAQDITERLRHQEQLARAEEALRHAQRMEAVGQLTGGVAHDFNNLLTIIRSSVEFLRRPNLAEERRTRYLEAVSDTVD
RAARLTNQLLAFARRQPLAPEVFDVGARLGEMADMLNAVTGGRVRIVTEISDARCHVRADPSQFETALVNLAMNARDAME
GEGTLTLRLTCGAALPPIRGHAGAPGPFAAVAVTDEGPGVAPDLLGRIFEPFFTTKAVGKGTGLGLSQVIGFTKQSGGDV
EVVSHVGRGATFTLYLPEVDPPPAAADDGAVMDAPAGEDRALCVLVVEDNLEVGRFCTQLLEDLGHATVWAHNAEAALAE
MEKVPFRFDAVFSDVVMPGMGGVELARRLRADHPALPVILTTGYSDALARDDAHGFELVRKPYSAEQVARALRDVLARHR
PGSIDRSGVQDRAG

Sequences:

>Translated_814_residues
MEIRARDWAETPLGPPDGWPSALRSALGLMLSCPTAMFLAWGPDLLCFYNDAYRPVLGYRLATALGRPFREVWASIWDEI
APLVSATLAGESQTLTDVMLDLSRDGRSEQGWWSFTYSPVLDDAGAISGLFCVTAETTARVLGEARLRESEDHFRHTVEL
NPQVPWTCDPQGNITSYSKRWLDLTGQAPGEPDGTGWTRALHPDDLPWTITVFTQCLASGETVDVDYRIRVARTGTYRWM
RARAQPRRAEDGAIVRWYGVVEDIHDRKLAEDRLREMNATLERRVAEALAQRKLWADVFETTDALVGALDTEYRFLAVNA
AYADEFEAIYGLRPAVGANLLDLLSGYPEQRAAAQAVWSRALAGEEFTVAEAFGDPGLKRPSYELKFTTLRDARGRRIGA
FQYAQDITERLRHQEQLARAEEALRHAQRMEAVGQLTGGVAHDFNNLLTIIRSSVEFLRRPNLAEERRTRYLEAVSDTVD
RAARLTNQLLAFARRQPLAPEVFDVGARLGEMADMLNAVTGGRVRIVTEISDARCHVRADPSQFETALVNLAMNARDAME
GEGTLTLRLTCGAALPPIRGHAGAPGPFAAVAVTDEGPGVAPDLLGRIFEPFFTTKAVGKGTGLGLSQVIGFTKQSGGDV
EVVSHVGRGATFTLYLPEVDPPPAAADDGAVMDAPAGEDRALCVLVVEDNLEVGRFCTQLLEDLGHATVWAHNAEAALAE
MEKVPFRFDAVFSDVVMPGMGGVELARRLRADHPALPVILTTGYSDALARDDAHGFELVRKPYSAEQVARALRDVLARHR
PGSIDRSGVQDRAG
>Mature_814_residues
MEIRARDWAETPLGPPDGWPSALRSALGLMLSCPTAMFLAWGPDLLCFYNDAYRPVLGYRLATALGRPFREVWASIWDEI
APLVSATLAGESQTLTDVMLDLSRDGRSEQGWWSFTYSPVLDDAGAISGLFCVTAETTARVLGEARLRESEDHFRHTVEL
NPQVPWTCDPQGNITSYSKRWLDLTGQAPGEPDGTGWTRALHPDDLPWTITVFTQCLASGETVDVDYRIRVARTGTYRWM
RARAQPRRAEDGAIVRWYGVVEDIHDRKLAEDRLREMNATLERRVAEALAQRKLWADVFETTDALVGALDTEYRFLAVNA
AYADEFEAIYGLRPAVGANLLDLLSGYPEQRAAAQAVWSRALAGEEFTVAEAFGDPGLKRPSYELKFTTLRDARGRRIGA
FQYAQDITERLRHQEQLARAEEALRHAQRMEAVGQLTGGVAHDFNNLLTIIRSSVEFLRRPNLAEERRTRYLEAVSDTVD
RAARLTNQLLAFARRQPLAPEVFDVGARLGEMADMLNAVTGGRVRIVTEISDARCHVRADPSQFETALVNLAMNARDAME
GEGTLTLRLTCGAALPPIRGHAGAPGPFAAVAVTDEGPGVAPDLLGRIFEPFFTTKAVGKGTGLGLSQVIGFTKQSGGDV
EVVSHVGRGATFTLYLPEVDPPPAAADDGAVMDAPAGEDRALCVLVVEDNLEVGRFCTQLLEDLGHATVWAHNAEAALAE
MEKVPFRFDAVFSDVVMPGMGGVELARRLRADHPALPVILTTGYSDALARDDAHGFELVRKPYSAEQVARALRDVLARHR
PGSIDRSGVQDRAG

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=296, Percent_Identity=32.4324324324324, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=28.9915966386555, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI48994928, Length=433, Percent_Identity=27.7136258660508, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI87081816, Length=402, Percent_Identity=25.6218905472637, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1788713, Length=366, Percent_Identity=25.1366120218579, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790300, Length=249, Percent_Identity=28.5140562248996, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 89317; Mature: 89317

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIRARDWAETPLGPPDGWPSALRSALGLMLSCPTAMFLAWGPDLLCFYNDAYRPVLGYR
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCEEEEECCCCHHHHHHH
LATALGRPFREVWASIWDEIAPLVSATLAGESQTLTDVMLDLSRDGRSEQGWWSFTYSPV
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEECCHH
LDDAGAISGLFCVTAETTARVLGEARLRESEDHFRHTVELNPQVPWTCDPQGNITSYSKR
HCCCCCCCCEEEEECHHHHHHHHHHHHCCCHHHHCEEEEECCCCCEEECCCCCCCHHHHH
WLDLTGQAPGEPDGTGWTRALHPDDLPWTITVFTQCLASGETVDVDYRIRVARTGTYRWM
HHEECCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHCCCEEEEEEEEEEEECCCHHHH
RARAQPRRAEDGAIVRWYGVVEDIHDRKLAEDRLREMNATLERRVAEALAQRKLWADVFE
HHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTDALVGALDTEYRFLAVNAAYADEFEAIYGLRPAVGANLLDLLSGYPEQRAAAQAVWSR
HHHHHHHHHCCCEEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
ALAGEEFTVAEAFGDPGLKRPSYELKFTTLRDARGRRIGAFQYAQDITERLRHQEQLARA
HHCCCCEEEHHHHCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EEALRHAQRMEAVGQLTGGVAHDFNNLLTIIRSSVEFLRRPNLAEERRTRYLEAVSDTVD
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RAARLTNQLLAFARRQPLAPEVFDVGARLGEMADMLNAVTGGRVRIVTEISDARCHVRAD
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEECC
PSQFETALVNLAMNARDAMEGEGTLTLRLTCGAALPPIRGHAGAPGPFAAVAVTDEGPGV
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCC
APDLLGRIFEPFFTTKAVGKGTGLGLSQVIGFTKQSGGDVEVVSHVGRGATFTLYLPEVD
CHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHCCCCCEEEEECCCCC
PPPAAADDGAVMDAPAGEDRALCVLVVEDNLEVGRFCTQLLEDLGHATVWAHNAEAALAE
CCCCCCCCCCEECCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCEEEECCHHHHHHH
MEKVPFRFDAVFSDVVMPGMGGVELARRLRADHPALPVILTTGYSDALARDDAHGFELVR
HHHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEECCCCHHHHCCCCHHHHHHH
KPYSAEQVARALRDVLARHRPGSIDRSGVQDRAG
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEIRARDWAETPLGPPDGWPSALRSALGLMLSCPTAMFLAWGPDLLCFYNDAYRPVLGYR
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCEEEEECCCCHHHHHHH
LATALGRPFREVWASIWDEIAPLVSATLAGESQTLTDVMLDLSRDGRSEQGWWSFTYSPV
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEECCHH
LDDAGAISGLFCVTAETTARVLGEARLRESEDHFRHTVELNPQVPWTCDPQGNITSYSKR
HCCCCCCCCEEEEECHHHHHHHHHHHHCCCHHHHCEEEEECCCCCEEECCCCCCCHHHHH
WLDLTGQAPGEPDGTGWTRALHPDDLPWTITVFTQCLASGETVDVDYRIRVARTGTYRWM
HHEECCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHCCCEEEEEEEEEEEECCCHHHH
RARAQPRRAEDGAIVRWYGVVEDIHDRKLAEDRLREMNATLERRVAEALAQRKLWADVFE
HHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTDALVGALDTEYRFLAVNAAYADEFEAIYGLRPAVGANLLDLLSGYPEQRAAAQAVWSR
HHHHHHHHHCCCEEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
ALAGEEFTVAEAFGDPGLKRPSYELKFTTLRDARGRRIGAFQYAQDITERLRHQEQLARA
HHCCCCEEEHHHHCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EEALRHAQRMEAVGQLTGGVAHDFNNLLTIIRSSVEFLRRPNLAEERRTRYLEAVSDTVD
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RAARLTNQLLAFARRQPLAPEVFDVGARLGEMADMLNAVTGGRVRIVTEISDARCHVRAD
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEECC
PSQFETALVNLAMNARDAMEGEGTLTLRLTCGAALPPIRGHAGAPGPFAAVAVTDEGPGV
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCC
APDLLGRIFEPFFTTKAVGKGTGLGLSQVIGFTKQSGGDVEVVSHVGRGATFTLYLPEVD
CHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHHHCCCCCEEEEECCCCC
PPPAAADDGAVMDAPAGEDRALCVLVVEDNLEVGRFCTQLLEDLGHATVWAHNAEAALAE
CCCCCCCCCCEECCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCEEEECCHHHHHHH
MEKVPFRFDAVFSDVVMPGMGGVELARRLRADHPALPVILTTGYSDALARDDAHGFELVR
HHHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEECCCCHHHHCCCCHHHHHHH
KPYSAEQVARALRDVLARHRPGSIDRSGVQDRAG
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA