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The map label for this gene is purC2 [H]

Identifier: 170749356

GI number: 170749356

Start: 3107838

End: 3108815

Strand: Reverse

Name: purC2 [H]

Synonym: Mrad2831_2949

Alternate gene names: 170749356

Gene position: 3108815-3107838 (Counterclockwise)

Preceding gene: 170749358

Following gene: 170749352

Centisome position: 51.15

GC content: 70.14

Gene sequence:

>978_bases
ATGAACACGGCAGATCTCGCCCCGCACGCGCATCAGGTCCTGCGCGACGCGACCCTGCCCGAGTTGCCCCGGCACTACCG
CGGCAAGGTTCGGGACAATTACGACCTCCCTGACGGCCGGCGCATCCTCATCACCTCGGACCGGATCAGCGCCTTCGACC
GGGCGCTCGCGGCCATCCCGTTCAAGGGCCAGGTCCTGACCCAGACCGCCCGCTACTGGTTCGAGCAGACCGCCGACCTC
TGCCCGAACCACGTCATCGCCTATCCCGACCCGAACGTGGTGGTCGGCCGGCGCCTCGAGATCCTACCCGTGGAGGTGGT
GGTGCGCGGCTACCTCGCGGGCACCACATCGACGTCGATCCTGACGCGCTACCGCGCCGGCGAGCGGGACATGTACGGCC
ACCGCTTCCCCGACGAGATGCGGCCGAACCAGCGGCTGCCGGAGGCGATCATCACGCCGACCACCAAGGCGTTCGACGGC
GGCCACGACGAGCCGCTCACCGAGGCGGAGATCCTCGAGCGCGGATTGCTGACGCGCGCGCAGTGGCGGACCGTGTCCGA
GGCGGCCCTGGCGCTGTTCGCGCGCGGGACGGCCCTGGCGGCGGAGCGCGGCCTGATCCTGGCCGACACGAAGTACGAGT
TCGGAACGGATCCGGAAGGCCGGATCGTCCTCGCCGACGAGATCCACACGCCGGACAGCAGCCGGTACTGGTTCGCCCAG
AGCTATCCCGAGCGCTTCGCCGCGGGTTCGGCCCCGGAGAGCTTCGACAAGGACTTCGTGCGCAACTGGGTCGTCGCCCG
CTGCGACCCCTACAAGGACCCGATCCCGGAGATTCCGGCCGAGGTCGTCCTGGAGACCGCCGCGGTCTACATCCGCGCCT
ACGAGACGATCACCGGCGCGCGCTTCGTCCTGCCGGACCCGGCGGAGGATCCCCTGGAGCGGATCCGGCGCAACATCGCC
GCCTATCTCGCGGCCTAG

Upstream 100 bases:

>100_bases
GCGCCGCGCGCCCTCGCGGGGGCCAGGACTGGAATTTCCCGGCCCGTCCGCGCACAGAGGTCCGACGGCGCGGTCGCCGT
TCAGCCTGACGGAAAGCCCG

Downstream 100 bases:

>100_bases
CTGCGCCACGCGGAGAGGGGTGCGGCGCCCGGCGCCGCACCCGGTCGAGCGTGTCAGGCCGCGACGGCGATCGGAGCCGG
CGACGGCGCGTCCATGGCGC

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase 2 [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MNTADLAPHAHQVLRDATLPELPRHYRGKVRDNYDLPDGRRILITSDRISAFDRALAAIPFKGQVLTQTARYWFEQTADL
CPNHVIAYPDPNVVVGRRLEILPVEVVVRGYLAGTTSTSILTRYRAGERDMYGHRFPDEMRPNQRLPEAIITPTTKAFDG
GHDEPLTEAEILERGLLTRAQWRTVSEAALALFARGTALAAERGLILADTKYEFGTDPEGRIVLADEIHTPDSSRYWFAQ
SYPERFAAGSAPESFDKDFVRNWVVARCDPYKDPIPEIPAEVVLETAAVYIRAYETITGARFVLPDPAEDPLERIRRNIA
AYLAA

Sequences:

>Translated_325_residues
MNTADLAPHAHQVLRDATLPELPRHYRGKVRDNYDLPDGRRILITSDRISAFDRALAAIPFKGQVLTQTARYWFEQTADL
CPNHVIAYPDPNVVVGRRLEILPVEVVVRGYLAGTTSTSILTRYRAGERDMYGHRFPDEMRPNQRLPEAIITPTTKAFDG
GHDEPLTEAEILERGLLTRAQWRTVSEAALALFARGTALAAERGLILADTKYEFGTDPEGRIVLADEIHTPDSSRYWFAQ
SYPERFAAGSAPESFDKDFVRNWVVARCDPYKDPIPEIPAEVVLETAAVYIRAYETITGARFVLPDPAEDPLERIRRNIA
AYLAA
>Mature_325_residues
MNTADLAPHAHQVLRDATLPELPRHYRGKVRDNYDLPDGRRILITSDRISAFDRALAAIPFKGQVLTQTARYWFEQTADL
CPNHVIAYPDPNVVVGRRLEILPVEVVVRGYLAGTTSTSILTRYRAGERDMYGHRFPDEMRPNQRLPEAIITPTTKAFDG
GHDEPLTEAEILERGLLTRAQWRTVSEAALALFARGTALAAERGLILADTKYEFGTDPEGRIVLADEIHTPDSSRYWFAQ
SYPERFAAGSAPESFDKDFVRNWVVARCDPYKDPIPEIPAEVVLETAAVYIRAYETITGARFVLPDPAEDPLERIRRNIA
AYLAA

Specific function: Unknown

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=306, Percent_Identity=34.3137254901961, Blast_Score=173, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013816
- InterPro:   IPR001636
- InterPro:   IPR018236 [H]

Pfam domain/function: PF01259 SAICAR_synt [H]

EC number: =6.3.2.6 [H]

Molecular weight: Translated: 36548; Mature: 36548

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS01057 SAICAR_SYNTHETASE_1 ; PS01058 SAICAR_SYNTHETASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTADLAPHAHQVLRDATLPELPRHYRGKVRDNYDLPDGRRILITSDRISAFDRALAAIP
CCCCCCCHHHHHHHHHCCCHHCCHHHCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHCC
FKGQVLTQTARYWFEQTADLCPNHVIAYPDPNVVVGRRLEILPVEVVVRGYLAGTTSTSI
CCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCEEEEEEHHHHHHHHHCCCCHHHH
LTRYRAGERDMYGHRFPDEMRPNQRLPEAIITPTTKAFDGGHDEPLTEAEILERGLLTRA
HHHHHCCCCCCCCCCCCHHCCCCCCCCHHHCCCCCHHCCCCCCCCCHHHHHHHHHHHHHH
QWRTVSEAALALFARGTALAAERGLILADTKYEFGTDPEGRIVLADEIHTPDSSRYWFAQ
HHHHHHHHHHHHHHCCHHHHHCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCCCEEEHH
SYPERFAAGSAPESFDKDFVRNWVVARCDPYKDPIPEIPAEVVLETAAVYIRAYETITGA
CCHHHHHCCCCCCHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
RFVLPDPAEDPLERIRRNIAAYLAA
EEECCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTADLAPHAHQVLRDATLPELPRHYRGKVRDNYDLPDGRRILITSDRISAFDRALAAIP
CCCCCCCHHHHHHHHHCCCHHCCHHHCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHCC
FKGQVLTQTARYWFEQTADLCPNHVIAYPDPNVVVGRRLEILPVEVVVRGYLAGTTSTSI
CCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEECCEEEEEEHHHHHHHHHCCCCHHHH
LTRYRAGERDMYGHRFPDEMRPNQRLPEAIITPTTKAFDGGHDEPLTEAEILERGLLTRA
HHHHHCCCCCCCCCCCCHHCCCCCCCCHHHCCCCCHHCCCCCCCCCHHHHHHHHHHHHHH
QWRTVSEAALALFARGTALAAERGLILADTKYEFGTDPEGRIVLADEIHTPDSSRYWFAQ
HHHHHHHHHHHHHHCCHHHHHCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCCCEEEHH
SYPERFAAGSAPESFDKDFVRNWVVARCDPYKDPIPEIPAEVVLETAAVYIRAYETITGA
CCHHHHHCCCCCCHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
RFVLPDPAEDPLERIRRNIAAYLAA
EEECCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]