| Definition | Methylobacterium radiotolerans JCM 2831 chromosome, complete genome. |
|---|---|
| Accession | NC_010505 |
| Length | 6,077,833 |
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The map label for this gene is fabG [H]
Identifier: 170749260
GI number: 170749260
Start: 3003612
End: 3004361
Strand: Reverse
Name: fabG [H]
Synonym: Mrad2831_2853
Alternate gene names: 170749260
Gene position: 3004361-3003612 (Counterclockwise)
Preceding gene: 170749261
Following gene: 170749259
Centisome position: 49.43
GC content: 71.47
Gene sequence:
>750_bases ATGAGACTGGACGGCAAGATCGCGCTCGTGACGGGGGCTGGCAGCGGCTTCGGGGCCGGGATCGCCCAGCGCTTCGCCGC GGAGGGCGCCAAGGTCGCCTGCGTCGACATCGACGGCGCGGCGGCCGAGCGTGTCGCCGCGGCAATCGGCGACAACGCGA TCGCGATCGCCGCCGATGTCGGCTTGGCCGCCGACGTCGCCGCCAGCGTCGCCGAGACGCGGCAGCGCTTCGGCGTGCCG AACGTTCTCGTCAACAACGCCGGCACCACCCATCGCAACAAGCCGCTGATGGAGGTGACCGAGGAGGACTTCGACCGGGT CTTCCGGGTCAACGTGAAGTCGATCTTCCACTACGTCCGGGAAGTCGCCCCGCTGATGCGCGACGCCGGCGGCGGCGCGA TCCTGAATGTCAGCTCGACGGCGGCGCTGCGGCCGCGCCCGGGGCTGACGTGGTACAACGCCTCCAAGGGGGCGGCGAGC CTCGCCTCGAAATCCCTCGCCCTGGAGCTGGCGCCCTGGAAGATCCGGGTGAACGCCCTCTGCCCGGTCATGGGCGCCAC GGGGCTCCTCGAGCACTTCATGGGCGTCCTCGACACGCCCGAGAATCGCGACCGCTTCATCGCCACGATCCCGCTCGGGC GCCTGTCGGAGGCGAGCGACATCGCGGCGGCGGCCCTGTTCCTCGCCTCCGACGAGGCGGCGTTCATCACCGGCGTCGAT CTGCCGGTCGACGGCGGCCGCACGGCCTGA
Upstream 100 bases:
>100_bases CCGGCGATCGACGAGCACGGGGCGCGGATCCGGGAGGAATTCGGTCGCCGCGACTGAGGACTGCGATACGACGGCAGAAC ATGAACGGCGGGAGGAGACG
Downstream 100 bases:
>100_bases GGAGTTCCCGATGGAATCCTATACCGAGATCCGCGAGGCGGTCGCCAAGCTCTGCGCCGGCTTCCCGGGACCGTACTGGC GGGCCCTCGACCGTGAGATG
Product: 3-ketoacyl-(acyl-carrier-protein) reductase
Products: NA
Alternate protein names: R-HPCDH; Aliphatic epoxide carboxylation component III [H]
Number of amino acids: Translated: 249; Mature: 249
Protein sequence:
>249_residues MRLDGKIALVTGAGSGFGAGIAQRFAAEGAKVACVDIDGAAAERVAAAIGDNAIAIAADVGLAADVAASVAETRQRFGVP NVLVNNAGTTHRNKPLMEVTEEDFDRVFRVNVKSIFHYVREVAPLMRDAGGGAILNVSSTAALRPRPGLTWYNASKGAAS LASKSLALELAPWKIRVNALCPVMGATGLLEHFMGVLDTPENRDRFIATIPLGRLSEASDIAAAALFLASDEAAFITGVD LPVDGGRTA
Sequences:
>Translated_249_residues MRLDGKIALVTGAGSGFGAGIAQRFAAEGAKVACVDIDGAAAERVAAAIGDNAIAIAADVGLAADVAASVAETRQRFGVP NVLVNNAGTTHRNKPLMEVTEEDFDRVFRVNVKSIFHYVREVAPLMRDAGGGAILNVSSTAALRPRPGLTWYNASKGAAS LASKSLALELAPWKIRVNALCPVMGATGLLEHFMGVLDTPENRDRFIATIPLGRLSEASDIAAAALFLASDEAAFITGVD LPVDGGRTA >Mature_249_residues MRLDGKIALVTGAGSGFGAGIAQRFAAEGAKVACVDIDGAAAERVAAAIGDNAIAIAADVGLAADVAASVAETRQRFGVP NVLVNNAGTTHRNKPLMEVTEEDFDRVFRVNVKSIFHYVREVAPLMRDAGGGAILNVSSTAALRPRPGLTWYNASKGAAS LASKSLALELAPWKIRVNALCPVMGATGLLEHFMGVLDTPENRDRFIATIPLGRLSEASDIAAAALFLASDEAAFITGVD LPVDGGRTA
Specific function: Catalyzes the oxidation of 2-(R)-hydroxyalkyl thioesters of CoM to 2-oxoalkyl thioesters of CoM. The enzyme highly specific for the R enantiomers [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=35.6275303643725, Blast_Score=125, Evalue=4e-29, Organism=Homo sapiens, GI7705925, Length=250, Percent_Identity=36, Blast_Score=117, Evalue=8e-27, Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=33.7209302325581, Blast_Score=114, Evalue=8e-26, Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=32, Blast_Score=108, Evalue=4e-24, Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=33.3333333333333, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=32.3651452282158, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI4758504, Length=256, Percent_Identity=33.203125, Blast_Score=102, Evalue=5e-22, Organism=Homo sapiens, GI59889578, Length=224, Percent_Identity=32.1428571428571, Blast_Score=101, Evalue=5e-22, Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=36.4640883977901, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI66933014, Length=247, Percent_Identity=30.7692307692308, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI33667109, Length=183, Percent_Identity=35.5191256830601, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI83715985, Length=256, Percent_Identity=31.640625, Blast_Score=88, Evalue=8e-18, Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=29.0836653386454, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI31542939, Length=217, Percent_Identity=30.4147465437788, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI142976729, Length=195, Percent_Identity=30.7692307692308, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI210032110, Length=207, Percent_Identity=29.4685990338164, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI302344755, Length=100, Percent_Identity=44, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=27.6923076923077, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI4504505, Length=199, Percent_Identity=32.1608040201005, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI40807363, Length=194, Percent_Identity=29.8969072164948, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI25282469, Length=217, Percent_Identity=27.6497695852535, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI310128830, Length=201, Percent_Identity=29.3532338308458, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI310115468, Length=201, Percent_Identity=29.3532338308458, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI7705855, Length=204, Percent_Identity=27.9411764705882, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI224922801, Length=164, Percent_Identity=31.0975609756098, Blast_Score=66, Evalue=4e-11, Organism=Homo sapiens, GI109715829, Length=246, Percent_Identity=25.609756097561, Blast_Score=64, Evalue=8e-11, Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=36.5853658536585, Blast_Score=131, Evalue=4e-32, Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=38.9558232931727, Blast_Score=128, Evalue=4e-31, Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=35.2941176470588, Blast_Score=125, Evalue=2e-30, Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=35.7976653696498, Blast_Score=111, Evalue=5e-26, Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=31.8897637795276, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI87082160, Length=257, Percent_Identity=31.5175097276265, Blast_Score=100, Evalue=7e-23, Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=35.3413654618474, Blast_Score=98, Evalue=5e-22, Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=29.1497975708502, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=30.8943089430894, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1789378, Length=241, Percent_Identity=28.6307053941909, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=30.6201550387597, Blast_Score=85, Evalue=4e-18, Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=31.3253012048193, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1788891, Length=220, Percent_Identity=29.5454545454545, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1787820, Length=176, Percent_Identity=30.6818181818182, Blast_Score=75, Evalue=3e-15, Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=35.4838709677419, Blast_Score=121, Evalue=4e-28, Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=32.1428571428571, Blast_Score=119, Evalue=1e-27, Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=36.1788617886179, Blast_Score=118, Evalue=2e-27, Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=35.9375, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=35.7429718875502, Blast_Score=114, Evalue=4e-26, Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=33.7301587301587, Blast_Score=114, Evalue=7e-26, Organism=Caenorhabditis elegans, GI17538480, Length=270, Percent_Identity=31.8518518518519, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17562910, Length=271, Percent_Identity=30.6273062730627, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=34.1463414634146, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=30.5660377358491, Blast_Score=103, Evalue=8e-23, Organism=Caenorhabditis elegans, GI193204405, Length=269, Percent_Identity=30.4832713754647, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17559104, Length=269, Percent_Identity=30.8550185873606, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=29.1044776119403, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=29.4339622641509, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17531453, Length=262, Percent_Identity=29.0076335877863, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17568967, Length=214, Percent_Identity=33.1775700934579, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17562990, Length=272, Percent_Identity=28.6764705882353, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=29.6992481203008, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=28.6792452830189, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17560150, Length=269, Percent_Identity=28.6245353159851, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17560220, Length=269, Percent_Identity=30.8550185873606, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI72000259, Length=265, Percent_Identity=29.0566037735849, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=26.7924528301887, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17564282, Length=195, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17563726, Length=267, Percent_Identity=27.7153558052434, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17538182, Length=255, Percent_Identity=32.156862745098, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17508651, Length=247, Percent_Identity=27.5303643724696, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17560332, Length=271, Percent_Identity=28.0442804428044, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17508895, Length=192, Percent_Identity=30.2083333333333, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17565030, Length=269, Percent_Identity=28.996282527881, Blast_Score=80, Evalue=8e-16, Organism=Caenorhabditis elegans, GI193203117, Length=196, Percent_Identity=28.0612244897959, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI193203115, Length=192, Percent_Identity=28.6458333333333, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17536025, Length=261, Percent_Identity=27.9693486590038, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17561272, Length=260, Percent_Identity=30, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17536651, Length=255, Percent_Identity=25.8823529411765, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17567345, Length=172, Percent_Identity=29.6511627906977, Blast_Score=66, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=188, Percent_Identity=30.3191489361702, Blast_Score=74, Evalue=2e-14, Organism=Saccharomyces cerevisiae, GI6324126, Length=258, Percent_Identity=28.6821705426357, Blast_Score=71, Evalue=2e-13, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=40.4761904761905, Blast_Score=143, Evalue=1e-34, Organism=Drosophila melanogaster, GI24644339, Length=261, Percent_Identity=38.6973180076628, Blast_Score=142, Evalue=2e-34, Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=38.4, Blast_Score=141, Evalue=3e-34, Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=38.3399209486166, Blast_Score=131, Evalue=5e-31, Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=35.2, Blast_Score=124, Evalue=5e-29, Organism=Drosophila melanogaster, GI24639444, Length=255, Percent_Identity=33.7254901960784, Blast_Score=117, Evalue=5e-27, Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=34.6456692913386, Blast_Score=115, Evalue=4e-26, Organism=Drosophila melanogaster, GI24644337, Length=255, Percent_Identity=36.4705882352941, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI17737361, Length=253, Percent_Identity=31.6205533596838, Blast_Score=94, Evalue=6e-20, Organism=Drosophila melanogaster, GI281364892, Length=220, Percent_Identity=32.2727272727273, Blast_Score=94, Evalue=7e-20, Organism=Drosophila melanogaster, GI161076933, Length=189, Percent_Identity=31.7460317460317, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI24584748, Length=189, Percent_Identity=31.7460317460317, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI18859837, Length=206, Percent_Identity=31.5533980582524, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI24640492, Length=197, Percent_Identity=27.9187817258883, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI24649181, Length=171, Percent_Identity=32.7485380116959, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI24584744, Length=183, Percent_Identity=28.9617486338798, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI28574402, Length=183, Percent_Identity=28.9617486338798, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24665243, Length=234, Percent_Identity=27.3504273504274, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI221331218, Length=234, Percent_Identity=27.3504273504274, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI21355631, Length=250, Percent_Identity=25.2, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24665247, Length=235, Percent_Identity=27.6595744680851, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI221331216, Length=235, Percent_Identity=27.6595744680851, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.268 [H]
Molecular weight: Translated: 25769; Mature: 25769
Theoretical pI: Translated: 5.76; Mature: 5.76
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRLDGKIALVTGAGSGFGAGIAQRFAAEGAKVACVDIDGAAAERVAAAIGDNAIAIAADV CCCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCEEEEEECC GLAADVAASVAETRQRFGVPNVLVNNAGTTHRNKPLMEVTEEDFDRVFRVNVKSIFHYVR CHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH EVAPLMRDAGGGAILNVSSTAALRPRPGLTWYNASKGAASLASKSLALELAPWKIRVNAL HHHHHHHCCCCCEEEEECCCEEECCCCCCEEECCCCCHHHHHHCCEEEEECCEEEEEEEC CPVMGATGLLEHFMGVLDTPENRDRFIATIPLGRLSEASDIAAAALFLASDEAAFITGVD CCHHCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHEEECCCCEEEEECC LPVDGGRTA CCCCCCCCC >Mature Secondary Structure MRLDGKIALVTGAGSGFGAGIAQRFAAEGAKVACVDIDGAAAERVAAAIGDNAIAIAADV CCCCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCEEEEEECC GLAADVAASVAETRQRFGVPNVLVNNAGTTHRNKPLMEVTEEDFDRVFRVNVKSIFHYVR CHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH EVAPLMRDAGGGAILNVSSTAALRPRPGLTWYNASKGAASLASKSLALELAPWKIRVNAL HHHHHHHCCCCCEEEEECCCEEECCCCCCEEECCCCCHHHHHHCCEEEEECCEEEEEEEC CPVMGATGLLEHFMGVLDTPENRDRFIATIPLGRLSEASDIAAAALFLASDEAAFITGVD CCHHCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHEEECCCCEEEEECC LPVDGGRTA CCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7704278; 9405410; 12524213 [H]