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The map label for this gene is pntAB [H]

Identifier: 170749206

GI number: 170749206

Start: 2939561

End: 2940016

Strand: Reverse

Name: pntAB [H]

Synonym: Mrad2831_2799

Alternate gene names: 170749206

Gene position: 2940016-2939561 (Counterclockwise)

Preceding gene: 170749207

Following gene: 170749205

Centisome position: 48.37

GC content: 68.2

Gene sequence:

>456_bases
ATGGCAAACGTCATCGTCCCTCCCGATCAGGCCGCCGATCAGGCCCGCGTGCTGGCCGACGCCGCGCGCGCGGCGGCCGC
GGTGGCGCGCAACGCCGCCGATCAGGCGCAGATCATCGCCGACGGCATGGGCCACGGGCTGAGCGCCGCCACGGGCGGCG
CGGTCGATCCCACGGTGTTCCGGCTCGCGATCTTCGTGCTGGCGATCTTCGTCGGATACTACGTGGTCTGGTCGGTGACC
CCGGCCCTGCACACCCCGCTCATGTCGGTCACCAATGCGATCTCGTCGGTGATCATCGTGGGCGCGATCCTGGCGGTCGG
CGTTCCGCTGATCGAGAAGGGCACCGGGCTGGCCCGGTTCTTCGGCTTCATCGGCATCGTGCTCGCCAGCGTGAACATCT
TCGGCGGCTTCCTCGTCACGCAACGCATGCTCGGCATGTACAAGAAGAAGGGCTGA

Upstream 100 bases:

>100_bases
AGCCGCCTCCGTGGGGCTGGCCAAGTCGGAGGCCAACAAGGCGTCCGGCACGGCCACCCCGGCGGGCGCGCAGTGAAGCC
CGGCCGAGAGGAGTAGCAGA

Downstream 100 bases:

>100_bases
GCCGGTGTCAGAGAACGTCTCCTCCCTTCTCTATATCGTCGCCGGCGTCCTGTTCATCATGGCGCTGCGGGGGCTCTCGC
ACCCCACAACCTCCCGGCAG

Product: PntAB, NAD(P) transhydrogenase, alpha2 subunit

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha 2; Proton-translocating transhydrogenase component 2; Pyridine nucleotide transhydrogenase subunit alpha 2; dII [H]

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MANVIVPPDQAADQARVLADAARAAAAVARNAADQAQIIADGMGHGLSAATGGAVDPTVFRLAIFVLAIFVGYYVVWSVT
PALHTPLMSVTNAISSVIIVGAILAVGVPLIEKGTGLARFFGFIGIVLASVNIFGGFLVTQRMLGMYKKKG

Sequences:

>Translated_151_residues
MANVIVPPDQAADQARVLADAARAAAAVARNAADQAQIIADGMGHGLSAATGGAVDPTVFRLAIFVLAIFVGYYVVWSVT
PALHTPLMSVTNAISSVIIVGAILAVGVPLIEKGTGLARFFGFIGIVLASVNIFGGFLVTQRMLGMYKKKG
>Mature_150_residues
ANVIVPPDQAADQARVLADAARAAAAVARNAADQAQIIADGMGHGLSAATGGAVDPTVFRLAIFVLAIFVGYYVVWSVTP
ALHTPLMSVTNAISSVIIVGAILAVGVPLIEKGTGLARFFGFIGIVLASVNIFGGFLVTQRMLGMYKKKG

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI122939155, Length=87, Percent_Identity=57.4712643678161, Blast_Score=85, Evalue=2e-17,
Organism=Homo sapiens, GI122939153, Length=87, Percent_Identity=57.4712643678161, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1787887, Length=99, Percent_Identity=55.5555555555556, Blast_Score=106, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17550456, Length=122, Percent_Identity=42.6229508196721, Blast_Score=92, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 15526; Mature: 15394

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANVIVPPDQAADQARVLADAARAAAAVARNAADQAQIIADGMGHGLSAATGGAVDPTVF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
RLAIFVLAIFVGYYVVWSVTPALHTPLMSVTNAISSVIIVGAILAVGVPLIEKGTGLARF
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHH
FGFIGIVLASVNIFGGFLVTQRMLGMYKKKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ANVIVPPDQAADQARVLADAARAAAAVARNAADQAQIIADGMGHGLSAATGGAVDPTVF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
RLAIFVLAIFVGYYVVWSVTPALHTPLMSVTNAISSVIIVGAILAVGVPLIEKGTGLARF
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHH
FGFIGIVLASVNIFGGFLVTQRMLGMYKKKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]