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The map label for this gene is arcA [H]

Identifier: 170748888

GI number: 170748888

Start: 2630092

End: 2631060

Strand: Reverse

Name: arcA [H]

Synonym: Mrad2831_2470

Alternate gene names: 170748888

Gene position: 2631060-2630092 (Counterclockwise)

Preceding gene: 170748890

Following gene: 170748887

Centisome position: 43.29

GC content: 75.23

Gene sequence:

>969_bases
ATGAGCGGCGAAGCCCAGCCGGACGCGGCGCGCAGCATCGCGCTGATCGGAGCGCCGATCGAGGTCGGCACCAGCGAGCC
CGGCGCCCTCATGGGACCGGCGGCCCTGCGCACGGCCGGTCTCGTCCGGGCGCTCGCCGAACTCGGCCACGCGATCGCGG
ATCGCGGCGACGTGGTCCCGGACGGACCTGCCGGGACGCGCGGGCTCGAGGGTGTCGCCGCCTGGACGCGGGCCGTGTCC
AGGGCCGTGGGGGACGCCCTCGACGCGGGGGCGCTCCCGCTGACCGCCGGCGGCGATCACAGCCTGTCCCTGGGCTCCGT
CGACGGGGTGATGCGGCACTCCGCGCGGCGCGGCCAGCCCGTCTTCGTGCTCTGGCTCGACGCCCACGCCGACTTCAACA
CGCCGGCGACCTCCCCCTCCGGCAACGTCCACGGCATGCCGCTCGCCGCCCTGTGCGGGGAGCCGGGATTCCCGTCCCTG
TTCGCCGAGCCGGCACCGGCGCCCCTGCCGCCCGCCCATGTCCACCTGTTCGGCCTCCGGTCGATCGACGCCGGCGAGCG
CGCCCTCGTGACGGCGCGCCGGGTCGGCGTCACCGACATGCGCACGATCGACGAGTTCGGAGTCGTGGCGCCCCTGCGGC
GGGTGCTCGACCGCGTCGCCGCGCAGGGGGCGCATCTCCATGTCAGCCTCGACATCGACTTCCTCGATCCGTCGATCGCC
CCGGCCGTGGGCACCACCGTTCCGGGCGGCGCGACCTTCCGGGAGGCGCACCTGATCATGGAGATGCTCCACGATTCCGG
GCTGGTCCGCTCCCTCGACGTGGTGGAACTCAACCCCTTCCTGGACGAGCGCGGCCGCAGCGCCCGGGTCTTGGTCGAGC
TGGTGGCGAGCCTGTTCGGCCGGCGCATCCTCGACCGGCCGACCGGGCCGATCGAGGCCGTGGCCGCAGAGCCGGCCGGA
CGCGCCTGA

Upstream 100 bases:

>100_bases
GGCCGATCCGGTCTCGCGGTCACCGTCATCGGACGGTTATGAGTCCGGATGGTAGAGCGGCCGCGGAGCACCGGTGCTCC
GGGACGGCGATGGAGGTGTG

Downstream 100 bases:

>100_bases
TGCACGGCCCCCTCGCTCCCGCACCCTCGCCCGAGAGGCTCGGGGCCGCGCCCGCGCGCCAGCGCTCCGACGGGCGCATC
CGGCTGCGCGTCGGGCCGGC

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MSGEAQPDAARSIALIGAPIEVGTSEPGALMGPAALRTAGLVRALAELGHAIADRGDVVPDGPAGTRGLEGVAAWTRAVS
RAVGDALDAGALPLTAGGDHSLSLGSVDGVMRHSARRGQPVFVLWLDAHADFNTPATSPSGNVHGMPLAALCGEPGFPSL
FAEPAPAPLPPAHVHLFGLRSIDAGERALVTARRVGVTDMRTIDEFGVVAPLRRVLDRVAAQGAHLHVSLDIDFLDPSIA
PAVGTTVPGGATFREAHLIMEMLHDSGLVRSLDVVELNPFLDERGRSARVLVELVASLFGRRILDRPTGPIEAVAAEPAG
RA

Sequences:

>Translated_322_residues
MSGEAQPDAARSIALIGAPIEVGTSEPGALMGPAALRTAGLVRALAELGHAIADRGDVVPDGPAGTRGLEGVAAWTRAVS
RAVGDALDAGALPLTAGGDHSLSLGSVDGVMRHSARRGQPVFVLWLDAHADFNTPATSPSGNVHGMPLAALCGEPGFPSL
FAEPAPAPLPPAHVHLFGLRSIDAGERALVTARRVGVTDMRTIDEFGVVAPLRRVLDRVAAQGAHLHVSLDIDFLDPSIA
PAVGTTVPGGATFREAHLIMEMLHDSGLVRSLDVVELNPFLDERGRSARVLVELVASLFGRRILDRPTGPIEAVAAEPAG
RA
>Mature_321_residues
SGEAQPDAARSIALIGAPIEVGTSEPGALMGPAALRTAGLVRALAELGHAIADRGDVVPDGPAGTRGLEGVAAWTRAVSR
AVGDALDAGALPLTAGGDHSLSLGSVDGVMRHSARRGQPVFVLWLDAHADFNTPATSPSGNVHGMPLAALCGEPGFPSLF
AEPAPAPLPPAHVHLFGLRSIDAGERALVTARRVGVTDMRTIDEFGVVAPLRRVLDRVAAQGAHLHVSLDIDFLDPSIAP
AVGTTVPGGATFREAHLIMEMLHDSGLVRSLDVVELNPFLDERGRSARVLVELVASLFGRRILDRPTGPIEAVAAEPAGR
A

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI4502215, Length=310, Percent_Identity=36.1290322580645, Blast_Score=178, Evalue=7e-45,
Organism=Homo sapiens, GI10947139, Length=308, Percent_Identity=33.4415584415584, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71996843, Length=239, Percent_Identity=28.4518828451883, Blast_Score=84, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6325146, Length=299, Percent_Identity=32.1070234113712, Blast_Score=135, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24638886, Length=312, Percent_Identity=34.6153846153846, Blast_Score=145, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 33227; Mature: 33096

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00626 RCC1_2 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGEAQPDAARSIALIGAPIEVGTSEPGALMGPAALRTAGLVRALAELGHAIADRGDVVP
CCCCCCCHHHHEEEEEECCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DGPAGTRGLEGVAAWTRAVSRAVGDALDAGALPLTAGGDHSLSLGSVDGVMRHSARRGQP
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEECCCHHHHHHHHHCCCCC
VFVLWLDAHADFNTPATSPSGNVHGMPLAALCGEPGFPSLFAEPAPAPLPPAHVHLFGLR
EEEEEEECCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHCCCCCCCCCCCEEEEEEEC
SIDAGERALVTARRVGVTDMRTIDEFGVVAPLRRVLDRVAAQGAHLHVSLDIDFLDPSIA
CCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCC
PAVGTTVPGGATFREAHLIMEMLHDSGLVRSLDVVELNPFLDERGRSARVLVELVASLFG
CCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECHHHHHCCCHHHHHHHHHHHHHH
RRILDRPTGPIEAVAAEPAGRA
HHHHCCCCCCHHEEECCCCCCC
>Mature Secondary Structure 
SGEAQPDAARSIALIGAPIEVGTSEPGALMGPAALRTAGLVRALAELGHAIADRGDVVP
CCCCCCHHHHEEEEEECCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DGPAGTRGLEGVAAWTRAVSRAVGDALDAGALPLTAGGDHSLSLGSVDGVMRHSARRGQP
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEECCCHHHHHHHHHCCCCC
VFVLWLDAHADFNTPATSPSGNVHGMPLAALCGEPGFPSLFAEPAPAPLPPAHVHLFGLR
EEEEEEECCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHCCCCCCCCCCCEEEEEEEC
SIDAGERALVTARRVGVTDMRTIDEFGVVAPLRRVLDRVAAQGAHLHVSLDIDFLDPSIA
CCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCC
PAVGTTVPGGATFREAHLIMEMLHDSGLVRSLDVVELNPFLDERGRSARVLVELVASLFG
CCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECHHHHHCCCHHHHHHHHHHHHHH
RRILDRPTGPIEAVAAEPAGRA
HHHHCCCCCCHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2806247; 3040404; 11743193; 11743194 [H]