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The map label for this gene is cpg2 [H]

Identifier: 170748835

GI number: 170748835

Start: 2578813

End: 2579964

Strand: Reverse

Name: cpg2 [H]

Synonym: Mrad2831_2417

Alternate gene names: 170748835

Gene position: 2579964-2578813 (Counterclockwise)

Preceding gene: 170748836

Following gene: 170748829

Centisome position: 42.45

GC content: 73.18

Gene sequence:

>1152_bases
ATGACCACACCTGACACCGACGTTCTCCGCTGGCTCGACGGGCAGGAGGGCGCGATGCTGGCGCTCCTCGAGGCGCTGGT
GAACATCGATTCCGGCTCCTACGACAAGCCGGGCGTCGACGCGGTCGGCATCCGCATCGCCGAGTTCCTCGCCGGCCACG
GCATCCCGGTCACGACGATTCCGGTCGACGGCTACGGCGACGCGCTGAAGGCGAGCGTGGCCGGGTCCGGCGGCGGCAAC
CGGCCGGTCGTGCTCATGGGCCACCGCGACACCGTCTTCCCGAAGGGGGAGCCGACGCGGCGGCCGTTCCGGGTCGCCGA
CGGCCGCGCCTACGGGCCGGGCGTCGCCGACATGAAGGCGGGCCTCGTGATGAACGCCTTCGTGCTGGCGGCCTACCACC
GGGCCGGCGGCGCGCCGGTGCCCCTCGTCGGCCTGTTCACCAGCGACGAGGAGATCGGCTCGCCGGCCTGTCGCCCGATC
ATCGAGGAGACCGCCCGGGGCGCCCGCGCGGTGCTGAATTCCGAGCCGGGGCGGCCGACCGGCAACGTCGTCACCGGCCG
CAAGGGCGGGGTGTTCATGCACCTCGAGGTGCTCGGCAGGGCTGCCCATTCCGGCGGCAACTACGCCGACGGGCGCAGCG
CCATCCTGGAGCTCGCCCACAAGACCGTCGCGCTCCACGCGCTCACCGACCTCGACCGCGGCACCACGGTGAATGTCGGC
CTGATCTCCGGCGGCCAGTCGGTGAACACCGTGGCGCCGCGGGTCACCTGCGAGATCGACCTGCGCTACGTGACCCCGCC
CGACCGCGAGGCCGCCATGAGCCGGATCGCGGAGATCGTGGCGGGATCGACGGTGCCCGACACCACCGCGCATCTCACCA
TCAAGGGCGAGTTCCTGCCGCTCGTGCAGGACGAGGCCTCGCGGGCGCTGTTCGAGACCTACGCCCGGGTGAGCGCGGAC
GGCGGCCATCCCGTCACCGGCGAGTTCGCCGGCGGCTGCGCCGATTCGGGCTTCACCGCCAGCGTCGGCTGCCCCACGCT
CTGCGCCGTGGGCCCGGTCGGCGGCAAGGCCCACTCGCCCGAGGAGTACCTGGAGGTGGGAAGCCTCGTGCCGCGGGCGC
GCGCGATGGCCGAGACCATCGCGGCGCTCTGA

Upstream 100 bases:

>100_bases
GCGGCGCAGCTCTCGCAGTCTGGCGTCGACCGGATCGCTTCACTCCGCTCGCACGGACGTCCGGGCCGCACGGTCCCGGC
AGCCCGGTATGAGGACCCCG

Downstream 100 bases:

>100_bases
CGGCGCAGAGACCGACCATCGCCGGCCCGGCCGCGCCGTAGCGGTCGCCGTCTCCGGGCGGACGCCGCGGCGCCGGACGC
GCCTGTCCGTTCGAGGCGCA

Product: peptidase M20

Products: NA

Alternate protein names: CPDG2; Folate hydrolase G2; Glutamate carboxypeptidase; Pteroylmonoglutamic acid hydrolase G2; Glucarpidase [H]

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MTTPDTDVLRWLDGQEGAMLALLEALVNIDSGSYDKPGVDAVGIRIAEFLAGHGIPVTTIPVDGYGDALKASVAGSGGGN
RPVVLMGHRDTVFPKGEPTRRPFRVADGRAYGPGVADMKAGLVMNAFVLAAYHRAGGAPVPLVGLFTSDEEIGSPACRPI
IEETARGARAVLNSEPGRPTGNVVTGRKGGVFMHLEVLGRAAHSGGNYADGRSAILELAHKTVALHALTDLDRGTTVNVG
LISGGQSVNTVAPRVTCEIDLRYVTPPDREAAMSRIAEIVAGSTVPDTTAHLTIKGEFLPLVQDEASRALFETYARVSAD
GGHPVTGEFAGGCADSGFTASVGCPTLCAVGPVGGKAHSPEEYLEVGSLVPRARAMAETIAAL

Sequences:

>Translated_383_residues
MTTPDTDVLRWLDGQEGAMLALLEALVNIDSGSYDKPGVDAVGIRIAEFLAGHGIPVTTIPVDGYGDALKASVAGSGGGN
RPVVLMGHRDTVFPKGEPTRRPFRVADGRAYGPGVADMKAGLVMNAFVLAAYHRAGGAPVPLVGLFTSDEEIGSPACRPI
IEETARGARAVLNSEPGRPTGNVVTGRKGGVFMHLEVLGRAAHSGGNYADGRSAILELAHKTVALHALTDLDRGTTVNVG
LISGGQSVNTVAPRVTCEIDLRYVTPPDREAAMSRIAEIVAGSTVPDTTAHLTIKGEFLPLVQDEASRALFETYARVSAD
GGHPVTGEFAGGCADSGFTASVGCPTLCAVGPVGGKAHSPEEYLEVGSLVPRARAMAETIAAL
>Mature_382_residues
TTPDTDVLRWLDGQEGAMLALLEALVNIDSGSYDKPGVDAVGIRIAEFLAGHGIPVTTIPVDGYGDALKASVAGSGGGNR
PVVLMGHRDTVFPKGEPTRRPFRVADGRAYGPGVADMKAGLVMNAFVLAAYHRAGGAPVPLVGLFTSDEEIGSPACRPII
EETARGARAVLNSEPGRPTGNVVTGRKGGVFMHLEVLGRAAHSGGNYADGRSAILELAHKTVALHALTDLDRGTTVNVGL
ISGGQSVNTVAPRVTCEIDLRYVTPPDREAAMSRIAEIVAGSTVPDTTAHLTIKGEFLPLVQDEASRALFETYARVSADG
GHPVTGEFAGGCADSGFTASVGCPTLCAVGPVGGKAHSPEEYLEVGSLVPRARAMAETIAAL

Specific function: Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate. This enzyme has a broad specificity [H]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=372, Percent_Identity=27.1505376344086, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR017150
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.17.11 [H]

Molecular weight: Translated: 39523; Mature: 39392

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPDTDVLRWLDGQEGAMLALLEALVNIDSGSYDKPGVDAVGIRIAEFLAGHGIPVTTI
CCCCCCHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEE
PVDGYGDALKASVAGSGGGNRPVVLMGHRDTVFPKGEPTRRPFRVADGRAYGPGVADMKA
ECCCCCCHHEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHH
GLVMNAFVLAAYHRAGGAPVPLVGLFTSDEEIGSPACRPIIEETARGARAVLNSEPGRPT
HHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCC
GNVVTGRKGGVFMHLEVLGRAAHSGGNYADGRSAILELAHKTVALHALTDLDRGTTVNVG
CCEEECCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
LISGGQSVNTVAPRVTCEIDLRYVTPPDREAAMSRIAEIVAGSTVPDTTAHLTIKGEFLP
EEECCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCEEE
LVQDEASRALFETYARVSADGGHPVTGEFAGGCADSGFTASVGCPTLCAVGPVGGKAHSP
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECCCCCHHEEECCCCCCCCCH
EEYLEVGSLVPRARAMAETIAAL
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTPDTDVLRWLDGQEGAMLALLEALVNIDSGSYDKPGVDAVGIRIAEFLAGHGIPVTTI
CCCCCHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEE
PVDGYGDALKASVAGSGGGNRPVVLMGHRDTVFPKGEPTRRPFRVADGRAYGPGVADMKA
ECCCCCCHHEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHH
GLVMNAFVLAAYHRAGGAPVPLVGLFTSDEEIGSPACRPIIEETARGARAVLNSEPGRPT
HHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCC
GNVVTGRKGGVFMHLEVLGRAAHSGGNYADGRSAILELAHKTVALHALTDLDRGTTVNVG
CCEEECCCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
LISGGQSVNTVAPRVTCEIDLRYVTPPDREAAMSRIAEIVAGSTVPDTTAHLTIKGEFLP
EEECCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCEEE
LVQDEASRALFETYARVSADGGHPVTGEFAGGCADSGFTASVGCPTLCAVGPVGGKAHSP
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECCCCCHHEEECCCCCCCCCH
EEYLEVGSLVPRARAMAETIAAL
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6396165; 3838935; 9083113 [H]