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The map label for this gene is glcB [H]

Identifier: 170748135

GI number: 170748135

Start: 1825170

End: 1827332

Strand: Reverse

Name: glcB [H]

Synonym: Mrad2831_1717

Alternate gene names: 170748135

Gene position: 1827332-1825170 (Counterclockwise)

Preceding gene: 170748137

Following gene: 170748128

Centisome position: 30.07

GC content: 73.46

Gene sequence:

>2163_bases
ATGTCGAATCTCGTCGTCGCCGAGGATCTCCGCACCTTCCTGTCCGAGGAGGCGCTGCCGGGGACCGGCCTCTCGGCCGA
CCAGTTCTGGTCGGGCTTCGCCGCGATCGTCCGCGATCTCGCACCGCACAACAGGGCGCTGCTCGACCGGCGGGACGGCC
TCCAGGCGGACATCGATTCCTGGCACCGCGACCATCGCGGCGAGCCGCACGACCCGGTGGCCTACGCGGCCTACCTGACG
CGGATCGGCTACCTGCAGCCGGAGCCCGCGGCCGTGCGGGTGACCACCGAGAACGTGGACGCGGAGATCGCCGCGATCGC
CGGGCCGCAGCTCGTGGTGCCGATCTCCAACGCCCGCTACGCGCTCAACGCCGCCAATGCCCGCTGGGGCAGCCTCTACG
ACGCCCTCTACGGCACCGACGCGATCCCGCAGGACGGCGACCGCGCGCCCGGCACCGGGTTCAACCCGGCCCGGGGCGCC
GCGGTGGTGGCCCGGACCAAGGCGTTCCTCGACGCGATCGCGCCGCTCAGCGTCGGCTCCTGGGCGGATGCCGTGGGCTT
CTCGGTGACGGACGGCCGCCTCGCCATCGACCTCGGCGCCGGCCGCAGCGCCGGCCTGACCGGCTCGGCCACCTTCGCGG
GCTTCACCGGCGACGCCGCGGCGCCGACCGCGCTCCTGCTGCGCCACAACGGCCTGCATATCGAGATCGTCATCGACCGC
GCGAGCCCGATCGGACGCACCGACCCGGCCGGCATCGCCGACGTGGTGCTGGAGGCCGCCCTCTCGACCATCATGGACAT
GGAGGATTCGGTGGCGGCCGTGGACTCGGCCGACAAGGTCGCGGTCTACCGGAGCTGGCTCGGCCTGATGCGCGGCGACC
TCGTCGCCACCCTGTCCAAGGGCGGCCGCACGATCGAGCGGCGGCTCGCCGCGGACCGGACCTTCACGGCCCCCGACGGC
GGGCGCCTGACCCTGCCGGGCCGGTCGCTGATGCTGGTCCGGCATGTCGGCCACCACATGTACACCGACGCGGTGACCCT
CGACGGCGCCGAAATTCCCGAGACGATCCTCGACGCGGCGGTCACCGCGCTGATCGCCCTGCACGACCTGAAGGGCACCG
GTCCGCTCCGCAACAGCCGGACCGGCTCGGTCTACATGGTCAAGCCCAAGCTGCACGGCCCCGACGAGGTCGCCTTCGCG
GTCGAGCTGTTCGGCCGGGTCGAGGCACTGGTCGGACTCGCGCCGCGGACGCTCAAGATCGGCGTCATGGACGAGGAGCG
GCGCACGACGCTGAACCTCAAGGCGGCGATCGCGGCGGCGGCGGACCGGCTGTTCTTCATCAACACGGGCTTCCTCGACC
GGACCGGCGACGAGATCCACACCTCGCTGGAGGCCGGCCCCGTGGTCCGCAAGGACGCCATGAAGGCGACCGCCTGGATC
AAGGCCTACGAGGACGGCAACGTCGATGCCGGCCTCGCCTGCGGCCTGCCGGGCCACGCCCAGATCGGCAAGGGCATGTG
GGCCGCCCCCGACCGGATGGCCGCGATGCTCGACGCCAAGGGCGCCCACCCGGAGGCGGGCGCCAACACCGCCTGGGTGC
CGTCGCCGACGGCCGCGACGCTCCACGCGCTCCACTACCATCAGGTGGATGTCCGCGCCCGCCAGGCGGCGCTCGCCGGC
CGGGCGCCCGCGACCCGCGCCGCCATGCTGACCCTGCCGCTCGCCGCGGGCGCGCTCGCGCCGGAGGCGGTGCGGGAGGA
GCTCGACAACAACTGCCAGGGAATCCTGGGCTACGTGGTCCGCTGGGTCGACCAGGGCGTCGGCTGCTCCAAGGTGCCGG
ACATCCACGAGGTCGGGCTGATGGAGGACCGCGCCACCCTGCGGATCTCCAGCCAGCACATCGCCAACTGGCTGCGCCAC
GGGATCGTGGATCGCGCGCAGGTCGCCGCCGCCCTGCGGCGGATGGCCGAAACCGTCGATCGCCAGAACGCCGGCGACCC
GGCCTACCGGCCGATGGCCCCGGGCTTCGACGGGCCGGCCTTCCGCGCCGCCGAGGCCCTGGTCTTCGAGGGCGCCGGCC
AGCCGAACGGCTACACCGAGTTCGTGCTGCACCGGTTCCGCCGGGAGGCGAAGCGCCTGGACGCCCCCGTTCGGGCGGCC
TGA

Upstream 100 bases:

>100_bases
CTCGCGGATGCCAAGCGATCTATCGAGGGGAAATCAAAAAATTTTCACGGCGCGTTCGATTTTTTCTGACGCGCGGGCCC
ACGCATCCCAGAGGATCGCC

Downstream 100 bases:

>100_bases
GGCCGCTCCCGGATCCCGGGCGCGCCCCGGGATCCGCCCCGGCGGGATCGCTGAGGCCTGCGCCCCGGCGGCCCGGCGAG
CCAGTCGACGGCCTGCGAAC

Product: malate synthase G

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 720; Mature: 719

Protein sequence:

>720_residues
MSNLVVAEDLRTFLSEEALPGTGLSADQFWSGFAAIVRDLAPHNRALLDRRDGLQADIDSWHRDHRGEPHDPVAYAAYLT
RIGYLQPEPAAVRVTTENVDAEIAAIAGPQLVVPISNARYALNAANARWGSLYDALYGTDAIPQDGDRAPGTGFNPARGA
AVVARTKAFLDAIAPLSVGSWADAVGFSVTDGRLAIDLGAGRSAGLTGSATFAGFTGDAAAPTALLLRHNGLHIEIVIDR
ASPIGRTDPAGIADVVLEAALSTIMDMEDSVAAVDSADKVAVYRSWLGLMRGDLVATLSKGGRTIERRLAADRTFTAPDG
GRLTLPGRSLMLVRHVGHHMYTDAVTLDGAEIPETILDAAVTALIALHDLKGTGPLRNSRTGSVYMVKPKLHGPDEVAFA
VELFGRVEALVGLAPRTLKIGVMDEERRTTLNLKAAIAAAADRLFFINTGFLDRTGDEIHTSLEAGPVVRKDAMKATAWI
KAYEDGNVDAGLACGLPGHAQIGKGMWAAPDRMAAMLDAKGAHPEAGANTAWVPSPTAATLHALHYHQVDVRARQAALAG
RAPATRAAMLTLPLAAGALAPEAVREELDNNCQGILGYVVRWVDQGVGCSKVPDIHEVGLMEDRATLRISSQHIANWLRH
GIVDRAQVAAALRRMAETVDRQNAGDPAYRPMAPGFDGPAFRAAEALVFEGAGQPNGYTEFVLHRFRREAKRLDAPVRAA

Sequences:

>Translated_720_residues
MSNLVVAEDLRTFLSEEALPGTGLSADQFWSGFAAIVRDLAPHNRALLDRRDGLQADIDSWHRDHRGEPHDPVAYAAYLT
RIGYLQPEPAAVRVTTENVDAEIAAIAGPQLVVPISNARYALNAANARWGSLYDALYGTDAIPQDGDRAPGTGFNPARGA
AVVARTKAFLDAIAPLSVGSWADAVGFSVTDGRLAIDLGAGRSAGLTGSATFAGFTGDAAAPTALLLRHNGLHIEIVIDR
ASPIGRTDPAGIADVVLEAALSTIMDMEDSVAAVDSADKVAVYRSWLGLMRGDLVATLSKGGRTIERRLAADRTFTAPDG
GRLTLPGRSLMLVRHVGHHMYTDAVTLDGAEIPETILDAAVTALIALHDLKGTGPLRNSRTGSVYMVKPKLHGPDEVAFA
VELFGRVEALVGLAPRTLKIGVMDEERRTTLNLKAAIAAAADRLFFINTGFLDRTGDEIHTSLEAGPVVRKDAMKATAWI
KAYEDGNVDAGLACGLPGHAQIGKGMWAAPDRMAAMLDAKGAHPEAGANTAWVPSPTAATLHALHYHQVDVRARQAALAG
RAPATRAAMLTLPLAAGALAPEAVREELDNNCQGILGYVVRWVDQGVGCSKVPDIHEVGLMEDRATLRISSQHIANWLRH
GIVDRAQVAAALRRMAETVDRQNAGDPAYRPMAPGFDGPAFRAAEALVFEGAGQPNGYTEFVLHRFRREAKRLDAPVRAA
>Mature_719_residues
SNLVVAEDLRTFLSEEALPGTGLSADQFWSGFAAIVRDLAPHNRALLDRRDGLQADIDSWHRDHRGEPHDPVAYAAYLTR
IGYLQPEPAAVRVTTENVDAEIAAIAGPQLVVPISNARYALNAANARWGSLYDALYGTDAIPQDGDRAPGTGFNPARGAA
VVARTKAFLDAIAPLSVGSWADAVGFSVTDGRLAIDLGAGRSAGLTGSATFAGFTGDAAAPTALLLRHNGLHIEIVIDRA
SPIGRTDPAGIADVVLEAALSTIMDMEDSVAAVDSADKVAVYRSWLGLMRGDLVATLSKGGRTIERRLAADRTFTAPDGG
RLTLPGRSLMLVRHVGHHMYTDAVTLDGAEIPETILDAAVTALIALHDLKGTGPLRNSRTGSVYMVKPKLHGPDEVAFAV
ELFGRVEALVGLAPRTLKIGVMDEERRTTLNLKAAIAAAADRLFFINTGFLDRTGDEIHTSLEAGPVVRKDAMKATAWIK
AYEDGNVDAGLACGLPGHAQIGKGMWAAPDRMAAMLDAKGAHPEAGANTAWVPSPTAATLHALHYHQVDVRARQAALAGR
APATRAAMLTLPLAAGALAPEAVREELDNNCQGILGYVVRWVDQGVGCSKVPDIHEVGLMEDRATLRISSQHIANWLRHG
IVDRAQVAAALRRMAETVDRQNAGDPAYRPMAPGFDGPAFRAAEALVFEGAGQPNGYTEFVLHRFRREAKRLDAPVRAA

Specific function: Accounts For Almost The Entire Malate-Synthesizing Activity In Cells Metabolizing Glyoxylate. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family. GlcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789348, Length=718, Percent_Identity=58.2172701949861, Blast_Score=837, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR001465
- InterPro:   IPR006253 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 76461; Mature: 76329

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLVVAEDLRTFLSEEALPGTGLSADQFWSGFAAIVRDLAPHNRALLDRRDGLQADIDS
CCCCEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHH
WHRDHRGEPHDPVAYAAYLTRIGYLQPEPAAVRVTTENVDAEIAAIAGPQLVVPISNARY
HHHHCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEECCCEEEEEECCCEE
ALNAANARWGSLYDALYGTDAIPQDGDRAPGTGFNPARGAAVVARTKAFLDAIAPLSVGS
EEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
WADAVGFSVTDGRLAIDLGAGRSAGLTGSATFAGFTGDAAAPTALLLRHNGLHIEIVIDR
CHHHCCCEEECCEEEEEECCCCCCCCCCCCEECCCCCCCCCCCEEEEECCCEEEEEEEEC
ASPIGRTDPAGIADVVLEAALSTIMDMEDSVAAVDSADKVAVYRSWLGLMRGDLVATLSK
CCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
GGRTIERRLAADRTFTAPDGGRLTLPGRSLMLVRHVGHHMYTDAVTLDGAEIPETILDAA
CCHHHHHHHHCCCCEECCCCCEEECCCCHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHH
VTALIALHDLKGTGPLRNSRTGSVYMVKPKLHGPDEVAFAVELFGRVEALVGLAPRTLKI
HHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEE
GVMDEERRTTLNLKAAIAAAADRLFFINTGFLDRTGDEIHTSLEAGPVVRKDAMKATAWI
EEECCCHHHEEHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHE
KAYEDGNVDAGLACGLPGHAQIGKGMWAAPDRMAAMLDAKGAHPEAGANTAWVPSPTAAT
EEECCCCCCCCEEECCCCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHH
LHALHYHQVDVRARQAALAGRAPATRAAMLTLPLAAGALAPEAVREELDNNCQGILGYVV
HHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEHHHHHCCCCHHHHHHHHCCCHHHHHHHHH
RWVDQGVGCSKVPDIHEVGLMEDRATLRISSQHIANWLRHGIVDRAQVAAALRRMAETVD
HHHHCCCCCCCCCCHHHCCCCCCCCEEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RQNAGDPAYRPMAPGFDGPAFRAAEALVFEGAGQPNGYTEFVLHRFRREAKRLDAPVRAA
HCCCCCCCCCCCCCCCCCCHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SNLVVAEDLRTFLSEEALPGTGLSADQFWSGFAAIVRDLAPHNRALLDRRDGLQADIDS
CCCEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHH
WHRDHRGEPHDPVAYAAYLTRIGYLQPEPAAVRVTTENVDAEIAAIAGPQLVVPISNARY
HHHHCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEECCCEEEEEECCCEE
ALNAANARWGSLYDALYGTDAIPQDGDRAPGTGFNPARGAAVVARTKAFLDAIAPLSVGS
EEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
WADAVGFSVTDGRLAIDLGAGRSAGLTGSATFAGFTGDAAAPTALLLRHNGLHIEIVIDR
CHHHCCCEEECCEEEEEECCCCCCCCCCCCEECCCCCCCCCCCEEEEECCCEEEEEEEEC
ASPIGRTDPAGIADVVLEAALSTIMDMEDSVAAVDSADKVAVYRSWLGLMRGDLVATLSK
CCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
GGRTIERRLAADRTFTAPDGGRLTLPGRSLMLVRHVGHHMYTDAVTLDGAEIPETILDAA
CCHHHHHHHHCCCCEECCCCCEEECCCCHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHH
VTALIALHDLKGTGPLRNSRTGSVYMVKPKLHGPDEVAFAVELFGRVEALVGLAPRTLKI
HHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEE
GVMDEERRTTLNLKAAIAAAADRLFFINTGFLDRTGDEIHTSLEAGPVVRKDAMKATAWI
EEECCCHHHEEHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHE
KAYEDGNVDAGLACGLPGHAQIGKGMWAAPDRMAAMLDAKGAHPEAGANTAWVPSPTAAT
EEECCCCCCCCEEECCCCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHH
LHALHYHQVDVRARQAALAGRAPATRAAMLTLPLAAGALAPEAVREELDNNCQGILGYVV
HHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEHHHHHCCCCHHHHHHHHCCCHHHHHHHHH
RWVDQGVGCSKVPDIHEVGLMEDRATLRISSQHIANWLRHGIVDRAQVAAALRRMAETVD
HHHHCCCCCCCCCCHHHCCCCCCCCEEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RQNAGDPAYRPMAPGFDGPAFRAAEALVFEGAGQPNGYTEFVLHRFRREAKRLDAPVRAA
HCCCCCCCCCCCCCCCCCCHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA