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The map label for this gene is dgoR [H]

Identifier: 170747748

GI number: 170747748

Start: 1386497

End: 1387237

Strand: Reverse

Name: dgoR [H]

Synonym: Mrad2831_1327

Alternate gene names: 170747748

Gene position: 1387237-1386497 (Counterclockwise)

Preceding gene: 170747764

Following gene: 170747745

Centisome position: 22.82

GC content: 72.87

Gene sequence:

>741_bases
GTGAGGCAGGAGCGCGGCCCGGAGAACATCACGCTGCCCCTCGCCACGGGGACGCGCCGCATCCACGGCTCGGTCGCCCG
CGATCTCGGTGTGGCGATCCTGGGCGGCCGCTACGCGCCCGGGGACGTGCTGCCCGGGGAGATCGAATTCTCTGAGAAAT
TGAACGTCTCGTGCACCGCCTATCGCGAGGCGATCCGCATCCTGAGCGCCAAGGGGCTCGTCGAGAGCCGCCCGCGCACC
GGCACCCGCGTCAGCCAGCGCAGCCGCTGGAACCTGCTCGATCCCGACATCCTCGCCTGGGCCTTCGAGTCGGAGCCGAG
CGAGTCCTTCATCCGCGACCTGTTCGAGCTGCGGATGATCGTCGAGCCGGCCGCGGCCGCGCTCGCGGCCGAGCGGCGCT
CGGGCCTCGACATCGCCCGGATGGGCCACGCCCTGGAGGAGATGGGTCGCCACGGCCTCGCCACCGAGGCCGGGCGGGCC
GCCGACCAGGCCTTCCACAACACGATCCTGGAAGCGGCCCGCAACGGGGCGCTGATGGCCCTGTCGAGCTCCATCGCCGC
CGCGGTCACGTGGACGACGATCTTCAAGCACCGCCGCCAGGGCCTGCCCCGGGACCCGATGCCGGATCACCGCGCCCTCT
ACGACGCGATCGTGGCGGGCGACCCGGACGCCGCCCGCGCGACCATGACCGAGCTGGTCCGCCTCGCCCTCGCCGACACG
GAGCTGGCGATGCGGCCCTGA

Upstream 100 bases:

>100_bases
TCCCGGTGCGGCGGGCGCTCCCCTTTCCGCTCCTACAACTTCAGGATACGATCGCGCCGTTCCTGCCCCGATCCGGTGGC
CCGGACCGGAGGTGGACGAG

Downstream 100 bases:

>100_bases
CGGTGCCGGCGGCGGGGTGCCGCTGGCCCGGACAGCGGCCGAGTGGCCTCAGGGGCCTCAGCGGCCTCAGTGGTTGTCGC
GCGGCACGCCCCGCGTCTGC

Product: GntR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MRQERGPENITLPLATGTRRIHGSVARDLGVAILGGRYAPGDVLPGEIEFSEKLNVSCTAYREAIRILSAKGLVESRPRT
GTRVSQRSRWNLLDPDILAWAFESEPSESFIRDLFELRMIVEPAAAALAAERRSGLDIARMGHALEEMGRHGLATEAGRA
ADQAFHNTILEAARNGALMALSSSIAAAVTWTTIFKHRRQGLPRDPMPDHRALYDAIVAGDPDAARATMTELVRLALADT
ELAMRP

Sequences:

>Translated_246_residues
MRQERGPENITLPLATGTRRIHGSVARDLGVAILGGRYAPGDVLPGEIEFSEKLNVSCTAYREAIRILSAKGLVESRPRT
GTRVSQRSRWNLLDPDILAWAFESEPSESFIRDLFELRMIVEPAAAALAAERRSGLDIARMGHALEEMGRHGLATEAGRA
ADQAFHNTILEAARNGALMALSSSIAAAVTWTTIFKHRRQGLPRDPMPDHRALYDAIVAGDPDAARATMTELVRLALADT
ELAMRP
>Mature_246_residues
MRQERGPENITLPLATGTRRIHGSVARDLGVAILGGRYAPGDVLPGEIEFSEKLNVSCTAYREAIRILSAKGLVESRPRT
GTRVSQRSRWNLLDPDILAWAFESEPSESFIRDLFELRMIVEPAAAALAAERRSGLDIARMGHALEEMGRHGLATEAGRA
ADQAFHNTILEAARNGALMALSSSIAAAVTWTTIFKHRRQGLPRDPMPDHRALYDAIVAGDPDAARATMTELVRLALADT
ELAMRP

Specific function: Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=201, Percent_Identity=37.3134328358209, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI48994961, Length=225, Percent_Identity=33.7777777777778, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1786303, Length=216, Percent_Identity=31.4814814814815, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082208, Length=219, Percent_Identity=29.2237442922374, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1790780, Length=217, Percent_Identity=30.8755760368664, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26858; Mature: 26858

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQERGPENITLPLATGTRRIHGSVARDLGVAILGGRYAPGDVLPGEIEFSEKLNVSCTA
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCCEECCCCCCCHHHH
YREAIRILSAKGLVESRPRTGTRVSQRSRWNLLDPDILAWAFESEPSESFIRDLFELRMI
HHHHHHHHHHCCHHHCCCCCCCHHHHHCCCCCCCHHHHEEECCCCCHHHHHHHHHHHHHH
VEPAAAALAAERRSGLDIARMGHALEEMGRHGLATEAGRAADQAFHNTILEAARNGALMA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEE
LSSSIAAAVTWTTIFKHRRQGLPRDPMPDHRALYDAIVAGDPDAARATMTELVRLALADT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
ELAMRP
HHHCCC
>Mature Secondary Structure
MRQERGPENITLPLATGTRRIHGSVARDLGVAILGGRYAPGDVLPGEIEFSEKLNVSCTA
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCCEECCCCCCCHHHH
YREAIRILSAKGLVESRPRTGTRVSQRSRWNLLDPDILAWAFESEPSESFIRDLFELRMI
HHHHHHHHHHCCHHHCCCCCCCHHHHHCCCCCCCHHHHEEECCCCCHHHHHHHHHHHHHH
VEPAAAALAAERRSGLDIARMGHALEEMGRHGLATEAGRAADQAFHNTILEAARNGALMA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEE
LSSSIAAAVTWTTIFKHRRQGLPRDPMPDHRALYDAIVAGDPDAARATMTELVRLALADT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
ELAMRP
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]