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The map label for this gene is fabH [C]

Identifier: 170747628

GI number: 170747628

Start: 1258452

End: 1259492

Strand: Reverse

Name: fabH [C]

Synonym: Mrad2831_1198

Alternate gene names: 170747628

Gene position: 1259492-1258452 (Counterclockwise)

Preceding gene: 170747629

Following gene: 170747627

Centisome position: 20.72

GC content: 70.7

Gene sequence:

>1041_bases
ATGGCTGACCTGCGGTTCTCGCGCGCGACCCTGGCGGGTCTCGTCACCACGGTCGGCGCGCGCGTCCAGGCCTTCGACGA
CGAGGCGGCCGGCCTCGGGCTCGCCCCCGAGGAGGCGGAGCGCCTCAAGCGGGCCATGGGCTTCGCGACCCGGCACGTCG
TCGCCGATCCCGGCACCACGACGGCGGATCTCTGCCTGCACTCGGCGCGCCACCTCCTGCGCGGCCTCGACCTGCAGCCC
GACGCCGTCGACGGCCTGATCCTCGTCACCCAGACGCCGGATTACAGCTCGCCGTCGACGTCGATCGGGATGCAGCACCG
CCTCGGCATGCGGACCGACACGCTCTGCTTCGACATCCGCCTCGGCTGCAGCGGCTTCGTCTACGGGTTGTCGGTCGCCT
ACAGCCTGGTCGAATCCGGCCTCGACCGCGTCCTGCTCTGCGTCGGCGACGTCGCGAGCCGCATGGTCGCGACCGGGGAC
CGGTCGATCACCCCGATCATGGGCGATGCCGGCGCCGCGGTGCTGATCGAGCGGCGCGAGAGCGAGAGCTTCTTCCAGCT
CCACAGCGACGGCTCGGGCGAGAAGGCCCTGTTCATCCCGCACAGCGGCCTCCGGGCCGACGCCGAGGACGCGGACAAGC
CCGGCACCATGCACATGGACGGGGCGCAGGTCTTCAACTTCACCCTGAAGCGCGTCCCGCCGCTGATCGAGGGCATCCTG
GCCTTCTCGGACACGCGCGCCGAGGACGTCGACTTCCTGGTCCTGCACCAGCCGAACAAGTACATCCTCAAGAACCTCCA
GCGCCGCCTGGGGCTCGACGACAGCAAGCTCCCGACCGGCACCCAGTCGGTCTACGGCAACCAGAACTCGGCCTCGATCC
CCGGCACGATCTCGGGCTTCCTCGCGGAGGCCTACGCGGGCCGGCGGGTGCGCTCGCTGCTCGCCGGCTTCGGGGTCGGG
CTGAGCTGGGGAGCCTGCACGATCACCACCGACCGGATCTTCGCGCCCCCGGTCATGACCTACGAGGAGACCACCCGATG
A

Upstream 100 bases:

>100_bases
CGCTACGTGCCGCTCGCCAACGAGAGCATCCTCGACAGCACGAAGTCGCCGCTCCGCCGCTTCCAGGGCTGGATCGACTA
CGTCGCCGAGACGGTCGAGC

Downstream 100 bases:

>100_bases
CCGAGGGCGCATTCCTGGACGAGCTCGGCACGATCCTCGACCAGCCGGGGCCGCTCGCCCGCGGGCAGAGCCTCGGGGCG
ATCGAGACCTTCGACTCGCT

Product: beta-ketoacyl-acyl-carrier-protein synthase I

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MADLRFSRATLAGLVTTVGARVQAFDDEAAGLGLAPEEAERLKRAMGFATRHVVADPGTTTADLCLHSARHLLRGLDLQP
DAVDGLILVTQTPDYSSPSTSIGMQHRLGMRTDTLCFDIRLGCSGFVYGLSVAYSLVESGLDRVLLCVGDVASRMVATGD
RSITPIMGDAGAAVLIERRESESFFQLHSDGSGEKALFIPHSGLRADAEDADKPGTMHMDGAQVFNFTLKRVPPLIEGIL
AFSDTRAEDVDFLVLHQPNKYILKNLQRRLGLDDSKLPTGTQSVYGNQNSASIPGTISGFLAEAYAGRRVRSLLAGFGVG
LSWGACTITTDRIFAPPVMTYEETTR

Sequences:

>Translated_346_residues
MADLRFSRATLAGLVTTVGARVQAFDDEAAGLGLAPEEAERLKRAMGFATRHVVADPGTTTADLCLHSARHLLRGLDLQP
DAVDGLILVTQTPDYSSPSTSIGMQHRLGMRTDTLCFDIRLGCSGFVYGLSVAYSLVESGLDRVLLCVGDVASRMVATGD
RSITPIMGDAGAAVLIERRESESFFQLHSDGSGEKALFIPHSGLRADAEDADKPGTMHMDGAQVFNFTLKRVPPLIEGIL
AFSDTRAEDVDFLVLHQPNKYILKNLQRRLGLDDSKLPTGTQSVYGNQNSASIPGTISGFLAEAYAGRRVRSLLAGFGVG
LSWGACTITTDRIFAPPVMTYEETTR
>Mature_345_residues
ADLRFSRATLAGLVTTVGARVQAFDDEAAGLGLAPEEAERLKRAMGFATRHVVADPGTTTADLCLHSARHLLRGLDLQPD
AVDGLILVTQTPDYSSPSTSIGMQHRLGMRTDTLCFDIRLGCSGFVYGLSVAYSLVESGLDRVLLCVGDVASRMVATGDR
SITPIMGDAGAAVLIERRESESFFQLHSDGSGEKALFIPHSGLRADAEDADKPGTMHMDGAQVFNFTLKRVPPLIEGILA
FSDTRAEDVDFLVLHQPNKYILKNLQRRLGLDDSKLPTGTQSVYGNQNSASIPGTISGFLAEAYAGRRVRSLLAGFGVGL
SWGACTITTDRIFAPPVMTYEETTR

Specific function: May catalyze the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=296, Percent_Identity=29.3918918918919, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 37168; Mature: 37036

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLRFSRATLAGLVTTVGARVQAFDDEAAGLGLAPEEAERLKRAMGFATRHVVADPGTT
CCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCCCC
TADLCLHSARHLLRGLDLQPDAVDGLILVTQTPDYSSPSTSIGMQHRLGMRTDTLCFDIR
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHCCCCCCCEEEEEE
LGCSGFVYGLSVAYSLVESGLDRVLLCVGDVASRMVATGDRSITPIMGDAGAAVLIERRE
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCEEEEEECC
SESFFQLHSDGSGEKALFIPHSGLRADAEDADKPGTMHMDGAQVFNFTLKRVPPLIEGIL
CCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHCCHHHHHHH
AFSDTRAEDVDFLVLHQPNKYILKNLQRRLGLDDSKLPTGTQSVYGNQNSASIPGTISGF
HHCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHH
LAEAYAGRRVRSLLAGFGVGLSWGACTITTDRIFAPPVMTYEETTR
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEECCCCCCCCCCCC
>Mature Secondary Structure 
ADLRFSRATLAGLVTTVGARVQAFDDEAAGLGLAPEEAERLKRAMGFATRHVVADPGTT
CCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCCCC
TADLCLHSARHLLRGLDLQPDAVDGLILVTQTPDYSSPSTSIGMQHRLGMRTDTLCFDIR
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHCCCCCCCEEEEEE
LGCSGFVYGLSVAYSLVESGLDRVLLCVGDVASRMVATGDRSITPIMGDAGAAVLIERRE
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCEEEEEECC
SESFFQLHSDGSGEKALFIPHSGLRADAEDADKPGTMHMDGAQVFNFTLKRVPPLIEGIL
CCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHCCHHHHHHH
AFSDTRAEDVDFLVLHQPNKYILKNLQRRLGLDDSKLPTGTQSVYGNQNSASIPGTISGF
HHCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHH
LAEAYAGRRVRSLLAGFGVGLSWGACTITTDRIFAPPVMTYEETTR
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]