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The map label for this gene is glyQ

Identifier: 170747572

GI number: 170747572

Start: 1201387

End: 1202298

Strand: Reverse

Name: glyQ

Synonym: Mrad2831_1140

Alternate gene names: 170747572

Gene position: 1202298-1201387 (Counterclockwise)

Preceding gene: 170747575

Following gene: 170747571

Centisome position: 19.78

GC content: 68.97

Gene sequence:

>912_bases
ATGTCCCAGAAAAAATCCTTCCAGGGTCTGATCCTGACGCTTCAGGAATTCTGGGCGGCGCAGGGCTGCGTGATCCTCCA
GCCCTACGACATGGAGGTCGGCGCCGGCACGTTCCACCCGGCCACGACCCTGCGGGCGCTCGGCCCGAAGCCCTGGAAGG
CGGCCTACGTCCAGCCGTCGCGCCGGCCCAAGGACGGCCGCTACGGCGAGAACCCGAACCGGCTCCAGCACTATTACCAG
TTCCAGGTGATCCTGAAGCCGAACCCGCCCAACCTGCAGGAGCTCTACCTCGCGTCGCTCGCCGCCATCGGCGTCGACCT
CAAGCTCCACGACATCCGCTTCGTCGAGGACGATTGGGAGAGCCCGACGCTGGGCGCCTGGGGCCTCGGCTGGGAGTGCT
GGTGCGACGGGATGGAGGTCAGCCAGTTCACCTATTTCCAGCAGGTCGCGGGCTTCGAGTGCGCGCCGGTGGCGGGCGAG
CTGACCTACGGGCTGGAGCGGCTCGCCATGTACGTCCAGGGTGTCGAGAACGTCTACGACCTCGACTTCAACGGCGCCGA
GGGGCCGGACCGGATCACCTACGGCGACGTGTTCCTGCAGGCCGAGCAGGAATATTCCCGCCACAACTTCGAGGCGGCCG
ACACGGCGATGCTGTTCCGCCAGTTCACCGACGCGGAGGCCGCCTGCCGGTCCTACCTCGCGGCGGGCGCGCCGGACGCG
GAGGGCGCGCGCCACCGCATGGCGCAGCCGGCCTACGACCAGTGCATCAAGGCGAGCCACGTCTTCAACCTGCTCGACGC
GCGCGGCGTGATCTCGGTGACGGAGCGCCAGAGCTACATCCTGCGCGTGCGCGAGCTGGCCAAGGCCTGCGGCGCGGCGT
GGCTGAAGACGGCGGCCGGCGGAGCCCCTTGA

Upstream 100 bases:

>100_bases
CTCGCGCCCGATACCCGCCGCCTTGCACCCCCGGCCGCCCGCACCTAAACCGGTCCGCCGGCGGCCCCAGCCGCCGCGCG
ATCCCGAGCCGCCGAGACCG

Downstream 100 bases:

>100_bases
GCCCTCGCGCGTTGCAACCCCCGCCAACCGGCGCGCCTCGGCGCGTCCGCAGACGCGGGAACCTCGTGATGAAGAAGACG
ATCCTCGCCCTCAGCCTCCT

Product: glycyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Glycine--tRNA ligase alpha subunit; GlyRS

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSQKKSFQGLILTLQEFWAAQGCVILQPYDMEVGAGTFHPATTLRALGPKPWKAAYVQPSRRPKDGRYGENPNRLQHYYQ
FQVILKPNPPNLQELYLASLAAIGVDLKLHDIRFVEDDWESPTLGAWGLGWECWCDGMEVSQFTYFQQVAGFECAPVAGE
LTYGLERLAMYVQGVENVYDLDFNGAEGPDRITYGDVFLQAEQEYSRHNFEAADTAMLFRQFTDAEAACRSYLAAGAPDA
EGARHRMAQPAYDQCIKASHVFNLLDARGVISVTERQSYILRVRELAKACGAAWLKTAAGGAP

Sequences:

>Translated_303_residues
MSQKKSFQGLILTLQEFWAAQGCVILQPYDMEVGAGTFHPATTLRALGPKPWKAAYVQPSRRPKDGRYGENPNRLQHYYQ
FQVILKPNPPNLQELYLASLAAIGVDLKLHDIRFVEDDWESPTLGAWGLGWECWCDGMEVSQFTYFQQVAGFECAPVAGE
LTYGLERLAMYVQGVENVYDLDFNGAEGPDRITYGDVFLQAEQEYSRHNFEAADTAMLFRQFTDAEAACRSYLAAGAPDA
EGARHRMAQPAYDQCIKASHVFNLLDARGVISVTERQSYILRVRELAKACGAAWLKTAAGGAP
>Mature_302_residues
SQKKSFQGLILTLQEFWAAQGCVILQPYDMEVGAGTFHPATTLRALGPKPWKAAYVQPSRRPKDGRYGENPNRLQHYYQF
QVILKPNPPNLQELYLASLAAIGVDLKLHDIRFVEDDWESPTLGAWGLGWECWCDGMEVSQFTYFQQVAGFECAPVAGEL
TYGLERLAMYVQGVENVYDLDFNGAEGPDRITYGDVFLQAEQEYSRHNFEAADTAMLFRQFTDAEAACRSYLAAGAPDAE
GARHRMAQPAYDQCIKASHVFNLLDARGVISVTERQSYILRVRELAKACGAAWLKTAAGGAP

Specific function: Unknown

COG id: COG0752

COG function: function code J; Glycyl-tRNA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1789983, Length=291, Percent_Identity=64.2611683848797, Blast_Score=385, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYGA_METRJ (B1M1W4)

Other databases:

- EMBL:   CP001001
- RefSeq:   YP_001753832.1
- ProteinModelPortal:   B1M1W4
- SMR:   B1M1W4
- GeneID:   6137157
- GenomeReviews:   CP001001_GR
- KEGG:   mrd:Mrad2831_1140
- HOGENOM:   HBG285316
- OMA:   CRRPTDG
- ProtClustDB:   PRK09348
- GO:   GO:0005737
- HAMAP:   MF_00254
- InterPro:   IPR006194
- InterPro:   IPR002310
- PRINTS:   PR01044
- TIGRFAMs:   TIGR00388

Pfam domain/function: PF02091 tRNA-synt_2e

EC number: =6.1.1.14

Molecular weight: Translated: 33793; Mature: 33662

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS50861 AA_TRNA_LIGASE_II_GLYAB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKKSFQGLILTLQEFWAAQGCVILQPYDMEVGAGTFHPATTLRALGPKPWKAAYVQPS
CCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCEEECCCC
RRPKDGRYGENPNRLQHYYQFQVILKPNPPNLQELYLASLAAIGVDLKLHDIRFVEDDWE
CCCCCCCCCCCHHHHEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEEEECCCCC
SPTLGAWGLGWECWCDGMEVSQFTYFQQVAGFECAPVAGELTYGLERLAMYVQGVENVYD
CCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHEE
LDFNGAEGPDRITYGDVFLQAEQEYSRHNFEAADTAMLFRQFTDAEAACRSYLAAGAPDA
CCCCCCCCCCCEEECCEEEEEHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
EGARHRMAQPAYDQCIKASHVFNLLDARGVISVTERQSYILRVRELAKACGAAWLKTAAG
CCHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
GAP
CCC
>Mature Secondary Structure 
SQKKSFQGLILTLQEFWAAQGCVILQPYDMEVGAGTFHPATTLRALGPKPWKAAYVQPS
CCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCEEECCCC
RRPKDGRYGENPNRLQHYYQFQVILKPNPPNLQELYLASLAAIGVDLKLHDIRFVEDDWE
CCCCCCCCCCCHHHHEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEEEECCCCC
SPTLGAWGLGWECWCDGMEVSQFTYFQQVAGFECAPVAGELTYGLERLAMYVQGVENVYD
CCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHEE
LDFNGAEGPDRITYGDVFLQAEQEYSRHNFEAADTAMLFRQFTDAEAACRSYLAAGAPDA
CCCCCCCCCCCEEECCEEEEEHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
EGARHRMAQPAYDQCIKASHVFNLLDARGVISVTERQSYILRVRELAKACGAAWLKTAAG
CCHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
GAP
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA