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The map label for this gene is ttuB [H]

Identifier: 170747567

GI number: 170747567

Start: 1195329

End: 1196651

Strand: Reverse

Name: ttuB [H]

Synonym: Mrad2831_1135

Alternate gene names: 170747567

Gene position: 1196651-1195329 (Counterclockwise)

Preceding gene: 170747570

Following gene: 170747566

Centisome position: 19.69

GC content: 68.48

Gene sequence:

>1323_bases
ATGCCGGTCCAAGCTGCCCCGCTGGGGGGCGCCTCCGCAGCCGCGGACCAGAAATCCTTCGCCGACCGCACCTACGCGAA
GGTGTTCTGGCGCCTCGTGCCGTTCCTGATGCTCTGCTACGTGGTGGCGTATCTCGACCGGGTGAATGTCGGCTTCGCCA
AGCTCCAGATGTCCCAGGAGCTGAAGTTCTCCGAGACGGTCTACGGCCTCGGCGCCGGCATCTTCTTCCTCGGCTACTTC
CTGTTCGAGGTGCCCTCGAACGTGATCCTGCACCGGGTCGGCGCCCGGGTGTGGATCGCCCGGATCATGATCACCTGGGG
GGTGATCTCCGGGGCGTTCCTGTTCGTGAACTCCGAGTGGAGCTTCTACGGGATGCGCTTCCTCCTCGGGCTCGCCGAGG
CCGGGTTCTACCCGGGCGTCATCCTCTACACGACCTCGTGGTTCCCGGCCCATCGGCGGGCCCGGGTGATCGCGGTGTTC
ATGGCCGCGATCCCGATCTCCGGCATCTTCGGCAACCCGCTCTCCGGCTGGATCATGGACGCGTTCAACGGCGCCCACGG
CCTGTCCGGCTGGCAGTGGATGTTCCTGATCGAGGCGGTCCCGGCGGTGCTGATCGGCCTCGCGGTGTTCTTCTACCTCG
ACAACCGCCCCGCCGAGGCCACGTGGCTGACCGACGCCGAGAAGCAGCTCCTCGAGCGCGACATCGCGGCCGACAACCAG
GGCAAGGAGTCGAGCCCGCACTCCATCGCCACCGTGTTCCGCAACGGCCGCGTGTGGTTCATGAGCCTGATCTACTTCGC
CTTCGTCACCGGCCAGTACGGGCTGACCTTCTGGATGCCGACGATCGTCAAGGCGTCGGGCGTGCAGGGCAACTTCAACA
TCGGCCTGATCAGCGCGATCCCCTTCGTCTGCGCGGCGATCGTGATGGTCCTGCTCGGCCGCTCCGCCGACCGGATGCGC
GAGCGCCGCTGGCACCTGATCATCCCGGCGCTGATCGGCGCGGTCGCCTTCGTGGTCTCGGCCAATGCCGGCTCGACGAC
GCTCGCCATCGCGGCGCTGTCGGTGGCGGCGGCCGGCGTGCTGACCTGCTCGCCCCTGTTCTGGTCGCTGCCCACGGCGT
TCCTCAGCGGCGCCGGCGCGGCGGCCGGCATCGCGCTGATCAACTCGGTGGGGAACCTCGCGGGCTTCGTCAGCCCCTAC
GTGATCGGCGCGCTGCGCGACGCCACCGGCAGCACCGCCACCGGCCTCTACGCGCTGGCCGCCATGCTGGTGGTCGGTTC
GGTCTGCGTGTTCGTCACGCCCGCCCGGATGGTCAACCGCTGA

Upstream 100 bases:

>100_bases
CAGCGCTGCCAAAAGGCGATATGGCACCGCCCCAGCGCCGCCCGACGAGCGGTGAAGACCAATGTCCGGCGGCCGTGCGG
CCCGGACCAGGGAGTACGCC

Downstream 100 bases:

>100_bases
CGCGCCGGATCCCGGCACGACCCGCCCCTCTCCCGCACGGGAGAGGGGACTTGCGTCTCACGCGGTGATGCGGAGGCGCC
CTCCCCTTCATGCAGGAGCC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MPVQAAPLGGASAAADQKSFADRTYAKVFWRLVPFLMLCYVVAYLDRVNVGFAKLQMSQELKFSETVYGLGAGIFFLGYF
LFEVPSNVILHRVGARVWIARIMITWGVISGAFLFVNSEWSFYGMRFLLGLAEAGFYPGVILYTTSWFPAHRRARVIAVF
MAAIPISGIFGNPLSGWIMDAFNGAHGLSGWQWMFLIEAVPAVLIGLAVFFYLDNRPAEATWLTDAEKQLLERDIAADNQ
GKESSPHSIATVFRNGRVWFMSLIYFAFVTGQYGLTFWMPTIVKASGVQGNFNIGLISAIPFVCAAIVMVLLGRSADRMR
ERRWHLIIPALIGAVAFVVSANAGSTTLAIAALSVAAAGVLTCSPLFWSLPTAFLSGAGAAAGIALINSVGNLAGFVSPY
VIGALRDATGSTATGLYALAAMLVVGSVCVFVTPARMVNR

Sequences:

>Translated_440_residues
MPVQAAPLGGASAAADQKSFADRTYAKVFWRLVPFLMLCYVVAYLDRVNVGFAKLQMSQELKFSETVYGLGAGIFFLGYF
LFEVPSNVILHRVGARVWIARIMITWGVISGAFLFVNSEWSFYGMRFLLGLAEAGFYPGVILYTTSWFPAHRRARVIAVF
MAAIPISGIFGNPLSGWIMDAFNGAHGLSGWQWMFLIEAVPAVLIGLAVFFYLDNRPAEATWLTDAEKQLLERDIAADNQ
GKESSPHSIATVFRNGRVWFMSLIYFAFVTGQYGLTFWMPTIVKASGVQGNFNIGLISAIPFVCAAIVMVLLGRSADRMR
ERRWHLIIPALIGAVAFVVSANAGSTTLAIAALSVAAAGVLTCSPLFWSLPTAFLSGAGAAAGIALINSVGNLAGFVSPY
VIGALRDATGSTATGLYALAAMLVVGSVCVFVTPARMVNR
>Mature_439_residues
PVQAAPLGGASAAADQKSFADRTYAKVFWRLVPFLMLCYVVAYLDRVNVGFAKLQMSQELKFSETVYGLGAGIFFLGYFL
FEVPSNVILHRVGARVWIARIMITWGVISGAFLFVNSEWSFYGMRFLLGLAEAGFYPGVILYTTSWFPAHRRARVIAVFM
AAIPISGIFGNPLSGWIMDAFNGAHGLSGWQWMFLIEAVPAVLIGLAVFFYLDNRPAEATWLTDAEKQLLERDIAADNQG
KESSPHSIATVFRNGRVWFMSLIYFAFVTGQYGLTFWMPTIVKASGVQGNFNIGLISAIPFVCAAIVMVLLGRSADRMRE
RRWHLIIPALIGAVAFVVSANAGSTTLAIAALSVAAAGVLTCSPLFWSLPTAFLSGAGAAAGIALINSVGNLAGFVSPYV
IGALRDATGSTATGLYALAAMLVVGSVCVFVTPARMVNR

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=397, Percent_Identity=21.9143576826196, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI87082071, Length=420, Percent_Identity=39.2857142857143, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI2367379, Length=386, Percent_Identity=24.6113989637306, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789515, Length=441, Percent_Identity=24.2630385487528, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI87082320, Length=416, Percent_Identity=22.3557692307692, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789152, Length=446, Percent_Identity=24.6636771300448, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI2367193, Length=260, Percent_Identity=24.2307692307692, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322025, Length=256, Percent_Identity=23.828125, Blast_Score=87, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6319876, Length=316, Percent_Identity=22.1518987341772, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319250, Length=235, Percent_Identity=23.4042553191489, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322612, Length=273, Percent_Identity=20.8791208791209, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6321698, Length=319, Percent_Identity=21.9435736677116, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321502, Length=382, Percent_Identity=23.5602094240838, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24583789, Length=376, Percent_Identity=23.936170212766, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24584153, Length=374, Percent_Identity=22.9946524064171, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24653727, Length=410, Percent_Identity=21.7073170731707, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI20130167, Length=417, Percent_Identity=22.7817745803357, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641682, Length=400, Percent_Identity=23.5, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47443; Mature: 47312

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVQAAPLGGASAAADQKSFADRTYAKVFWRLVPFLMLCYVVAYLDRVNVGFAKLQMSQE
CCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
LKFSETVYGLGAGIFFLGYFLFEVPSNVILHRVGARVWIARIMITWGVISGAFLFVNSEW
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCC
SFYGMRFLLGLAEAGFYPGVILYTTSWFPAHRRARVIAVFMAAIPISGIFGNPLSGWIMD
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AFNGAHGLSGWQWMFLIEAVPAVLIGLAVFFYLDNRPAEATWLTDAEKQLLERDIAADNQ
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCC
GKESSPHSIATVFRNGRVWFMSLIYFAFVTGQYGLTFWMPTIVKASGVQGNFNIGLISAI
CCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHH
PFVCAAIVMVLLGRSADRMRERRWHLIIPALIGAVAFVVSANAGSTTLAIAALSVAAAGV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LTCSPLFWSLPTAFLSGAGAAAGIALINSVGNLAGFVSPYVIGALRDATGSTATGLYALA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
AMLVVGSVCVFVTPARMVNR
HHHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure 
PVQAAPLGGASAAADQKSFADRTYAKVFWRLVPFLMLCYVVAYLDRVNVGFAKLQMSQE
CCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
LKFSETVYGLGAGIFFLGYFLFEVPSNVILHRVGARVWIARIMITWGVISGAFLFVNSEW
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCC
SFYGMRFLLGLAEAGFYPGVILYTTSWFPAHRRARVIAVFMAAIPISGIFGNPLSGWIMD
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AFNGAHGLSGWQWMFLIEAVPAVLIGLAVFFYLDNRPAEATWLTDAEKQLLERDIAADNQ
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCC
GKESSPHSIATVFRNGRVWFMSLIYFAFVTGQYGLTFWMPTIVKASGVQGNFNIGLISAI
CCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHH
PFVCAAIVMVLLGRSADRMRERRWHLIIPALIGAVAFVVSANAGSTTLAIAALSVAAAGV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LTCSPLFWSLPTAFLSGAGAAAGIALINSVGNLAGFVSPYVIGALRDATGSTATGLYALA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
AMLVVGSVCVFVTPARMVNR
HHHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]