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The map label for this gene is ctaD [H]

Identifier: 170747469

GI number: 170747469

Start: 1089955

End: 1091631

Strand: Reverse

Name: ctaD [H]

Synonym: Mrad2831_1037

Alternate gene names: 170747469

Gene position: 1091631-1089955 (Counterclockwise)

Preceding gene: 170747470

Following gene: 170747468

Centisome position: 17.96

GC content: 65.65

Gene sequence:

>1677_bases
ATGAGCGCATCGGGCAGCATCGGCGGCACCGCCCGCCGGGAACCCCACGCCCCGGAATCCACGATCGGGCGCAAGGCCGA
CTACCTGCACGCGGAATCGACTCTGCGCTCGTGGTTCCTCACCACCGACCACAAGCGCATCGCGCTCCTCTATCTCGCCT
CGATCACCGGCTTCTTCGTGATCGGCGCCCTGGCGGCCGGCGTGGTGCGCCTCGCGCTGATCGTGCCCAATGGCGCGATC
ATGACCAACGACACCTACAACAAGGCCTTCACCATCCACGGGGTGGTGATGGTCTGGTTCTTCCTGATCCCGTCGATCCC
CGCGACCTTCGGCAACTTCCTGATCCCCTTGATGATCGGGGCCAGGGACCTCGCCTTCCCGAAGCTCAACCTGACGAGCT
GGTACGTGTTCATGGCGGGCGCCCTGTTCACCCTGGTCTCGGTGGTGCTGGGCGGCGTCGATACCGGCTGGACCTTCTAC
GCCCCGCTCTCGACGGCCTTCTCGAACACCTGGGTGCTGCCGGCGCTGATCGGCGTGACAATCGTGGGCTTCTCGTCGAT
CCTGACGGGGCTCAACTTCGTGGTCACGATCCACACCATGCGGGCGCCCGGCATGACGTGGTTCAAGCTGCCGATCTTCG
TCTGGGCGCACTACGCCACGAGCCTGATCTTCCTGCTGGCGACGCCCGTCATCACCACCGCGCTGATCCTGCTGATCGCG
GAGCGCGCCTTCCACATCGGCGTGTTCGACCCGGCCTATGGCGGCGATCCGGTGCTGTTCCAGCACCTGTTCTGGTTCTA
CTCGCACCCGGCCGTGTACATCATGGTCCTGCCCGGCATGGGGGTGATCTCCGAGATCGTCCCGGCCTTCGCGCAGAAGA
AGCTGTTCGGCTACCGCTTCGTCGCCTACGCGTCGATCGGGCTGGCCTCCGTGACCTTCTTCGTCTGGGGCCACCACATG
TTCGTCAACGGCCAGAGCGACCTGGCCTCGCTGGTCTTCTCCGCCCTGTCCTTCGCGGTGGCGGTGCCCTCGGCCGTGAA
GGTCTACAACTGGACCGCCACGATCCATAAGGGAGCCCTGCGGCTCGACACGCCGATGCTCTACGCGATGGGCTATATCG
GCCTGTTCGTGCTCGGCGGCCTCACCGGCCTCTACCTCGCGACGCTCGCCATCAACCAGCACATCCACGCGACCTACTTC
GTGGTCGCGCATTTCCACTACATCATGGTCGGCGGCACGGTGCTGGCCTTCCTCGGCGGGCTGCACTTCTGGTGGCCGAA
ATTCACCGGCCGGATGTACAGCGAGCCCTGGGGCCGGGTCTCGGCGCTGCTGATCTTCCTCGGCTTCAACGTGACCTTCT
TCCCGCAATTCATCCTGGGCTATCTCGGGATGCCGCGGCGCTACGCGACCTACCCGGCCGAGTTCCAGCTCCTGAACGTT
CTGTCCTCGGCGGGCGCCACGATCCTGGCGGCGGGCTACCTCTTCCCGATGCTCTACCTCGTCTATTCCCTGTGGTTCGG
GCGGAAGGCGCCCGCCAATCCGTGGAACGCGAAGGGGCTCGAGTGGGAGACCGCCTCCCCGCCGCCGACGCACAATTTCC
TGTCGCCGCCGGAGGTGCCGCGCATCCCCTACGACTACCCGATCCAGGCCCAGGAATCCCGGGACCAGCACGGATGA

Upstream 100 bases:

>100_bases
TCCCGGCGGACGAGCTCGGCACGCTGATCGATTTCCTGAAATCCTACGCGGGCCCGGCCTCCGGCAAGGCCGCGGACGCG
ACGCCGCCGGGAGCGACACG

Downstream 100 bases:

>100_bases
GCGCGCCCCTGGCCGACGGCGTCGGGGTCGCCCGCGCGCACCATTTCGAGACCGTCGCGCAGCAGCGCGCGGCGGCGACG
CTCGGCATCTGGGCGTGGCT

Product: cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 558; Mature: 557

Protein sequence:

>558_residues
MSASGSIGGTARREPHAPESTIGRKADYLHAESTLRSWFLTTDHKRIALLYLASITGFFVIGALAAGVVRLALIVPNGAI
MTNDTYNKAFTIHGVVMVWFFLIPSIPATFGNFLIPLMIGARDLAFPKLNLTSWYVFMAGALFTLVSVVLGGVDTGWTFY
APLSTAFSNTWVLPALIGVTIVGFSSILTGLNFVVTIHTMRAPGMTWFKLPIFVWAHYATSLIFLLATPVITTALILLIA
ERAFHIGVFDPAYGGDPVLFQHLFWFYSHPAVYIMVLPGMGVISEIVPAFAQKKLFGYRFVAYASIGLASVTFFVWGHHM
FVNGQSDLASLVFSALSFAVAVPSAVKVYNWTATIHKGALRLDTPMLYAMGYIGLFVLGGLTGLYLATLAINQHIHATYF
VVAHFHYIMVGGTVLAFLGGLHFWWPKFTGRMYSEPWGRVSALLIFLGFNVTFFPQFILGYLGMPRRYATYPAEFQLLNV
LSSAGATILAAGYLFPMLYLVYSLWFGRKAPANPWNAKGLEWETASPPPTHNFLSPPEVPRIPYDYPIQAQESRDQHG

Sequences:

>Translated_558_residues
MSASGSIGGTARREPHAPESTIGRKADYLHAESTLRSWFLTTDHKRIALLYLASITGFFVIGALAAGVVRLALIVPNGAI
MTNDTYNKAFTIHGVVMVWFFLIPSIPATFGNFLIPLMIGARDLAFPKLNLTSWYVFMAGALFTLVSVVLGGVDTGWTFY
APLSTAFSNTWVLPALIGVTIVGFSSILTGLNFVVTIHTMRAPGMTWFKLPIFVWAHYATSLIFLLATPVITTALILLIA
ERAFHIGVFDPAYGGDPVLFQHLFWFYSHPAVYIMVLPGMGVISEIVPAFAQKKLFGYRFVAYASIGLASVTFFVWGHHM
FVNGQSDLASLVFSALSFAVAVPSAVKVYNWTATIHKGALRLDTPMLYAMGYIGLFVLGGLTGLYLATLAINQHIHATYF
VVAHFHYIMVGGTVLAFLGGLHFWWPKFTGRMYSEPWGRVSALLIFLGFNVTFFPQFILGYLGMPRRYATYPAEFQLLNV
LSSAGATILAAGYLFPMLYLVYSLWFGRKAPANPWNAKGLEWETASPPPTHNFLSPPEVPRIPYDYPIQAQESRDQHG
>Mature_557_residues
SASGSIGGTARREPHAPESTIGRKADYLHAESTLRSWFLTTDHKRIALLYLASITGFFVIGALAAGVVRLALIVPNGAIM
TNDTYNKAFTIHGVVMVWFFLIPSIPATFGNFLIPLMIGARDLAFPKLNLTSWYVFMAGALFTLVSVVLGGVDTGWTFYA
PLSTAFSNTWVLPALIGVTIVGFSSILTGLNFVVTIHTMRAPGMTWFKLPIFVWAHYATSLIFLLATPVITTALILLIAE
RAFHIGVFDPAYGGDPVLFQHLFWFYSHPAVYIMVLPGMGVISEIVPAFAQKKLFGYRFVAYASIGLASVTFFVWGHHMF
VNGQSDLASLVFSALSFAVAVPSAVKVYNWTATIHKGALRLDTPMLYAMGYIGLFVLGGLTGLYLATLAINQHIHATYFV
VAHFHYIMVGGTVLAFLGGLHFWWPKFTGRMYSEPWGRVSALLIFLGFNVTFFPQFILGYLGMPRRYATYPAEFQLLNVL
SSAGATILAAGYLFPMLYLVYSLWFGRKAPANPWNAKGLEWETASPPPTHNFLSPPEVPRIPYDYPIQAQESRDQHG

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=505, Percent_Identity=38.019801980198, Blast_Score=343, Evalue=3e-94,
Organism=Escherichia coli, GI1786634, Length=518, Percent_Identity=33.5907335907336, Blast_Score=310, Evalue=2e-85,
Organism=Saccharomyces cerevisiae, GI6226519, Length=532, Percent_Identity=36.6541353383459, Blast_Score=336, Evalue=7e-93,
Organism=Saccharomyces cerevisiae, GI6226524, Length=324, Percent_Identity=36.4197530864198, Blast_Score=212, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6226523, Length=249, Percent_Identity=36.144578313253, Blast_Score=136, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 61539; Mature: 61408

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASGSIGGTARREPHAPESTIGRKADYLHAESTLRSWFLTTDHKRIALLYLASITGFFV
CCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHH
IGALAAGVVRLALIVPNGAIMTNDTYNKAFTIHGVVMVWFFLIPSIPATFGNFLIPLMIG
HHHHHHHHHHHHEEECCCEEEECCCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
ARDLAFPKLNLTSWYVFMAGALFTLVSVVLGGVDTGWTFYAPLSTAFSNTWVLPALIGVT
CHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHCCCCHHHHHHHHH
IVGFSSILTGLNFVVTIHTMRAPGMTWFKLPIFVWAHYATSLIFLLATPVITTALILLIA
HHHHHHHHHCCEEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERAFHIGVFDPAYGGDPVLFQHLFWFYSHPAVYIMVLPGMGVISEIVPAFAQKKLFGYRF
HHHHEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
VAYASIGLASVTFFVWGHHMFVNGQSDLASLVFSALSFAVAVPSAVKVYNWTATIHKGAL
HHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCHHEEEEEEEHHCCCCE
RLDTPMLYAMGYIGLFVLGGLTGLYLATLAINQHIHATYFVVAHFHYIMVGGTVLAFLGG
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LHFWWPKFTGRMYSEPWGRVSALLIFLGFNVTFFPQFILGYLGMPRRYATYPAEFQLLNV
HHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHCCCCHHHHHHHH
LSSAGATILAAGYLFPMLYLVYSLWFGRKAPANPWNAKGLEWETASPPPTHNFLSPPEVP
HHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RIPYDYPIQAQESRDQHG
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SASGSIGGTARREPHAPESTIGRKADYLHAESTLRSWFLTTDHKRIALLYLASITGFFV
CCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHH
IGALAAGVVRLALIVPNGAIMTNDTYNKAFTIHGVVMVWFFLIPSIPATFGNFLIPLMIG
HHHHHHHHHHHHEEECCCEEEECCCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
ARDLAFPKLNLTSWYVFMAGALFTLVSVVLGGVDTGWTFYAPLSTAFSNTWVLPALIGVT
CHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHCCCCHHHHHHHHH
IVGFSSILTGLNFVVTIHTMRAPGMTWFKLPIFVWAHYATSLIFLLATPVITTALILLIA
HHHHHHHHHCCEEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERAFHIGVFDPAYGGDPVLFQHLFWFYSHPAVYIMVLPGMGVISEIVPAFAQKKLFGYRF
HHHHEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
VAYASIGLASVTFFVWGHHMFVNGQSDLASLVFSALSFAVAVPSAVKVYNWTATIHKGAL
HHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCHHEEEEEEEHHCCCCE
RLDTPMLYAMGYIGLFVLGGLTGLYLATLAINQHIHATYFVVAHFHYIMVGGTVLAFLGG
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LHFWWPKFTGRMYSEPWGRVSALLIFLGFNVTFFPQFILGYLGMPRRYATYPAEFQLLNV
HHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHCCCCHHHHHHHH
LSSAGATILAAGYLFPMLYLVYSLWFGRKAPANPWNAKGLEWETASPPPTHNFLSPPEVP
HHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RIPYDYPIQAQESRDQHG
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8387368; 8905231 [H]