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The map label for this gene is acyII [H]

Identifier: 170747331

GI number: 170747331

Start: 939681

End: 942038

Strand: Reverse

Name: acyII [H]

Synonym: Mrad2831_0898

Alternate gene names: 170747331

Gene position: 942038-939681 (Counterclockwise)

Preceding gene: 170747332

Following gene: 170747330

Centisome position: 15.5

GC content: 76.04

Gene sequence:

>2358_bases
GTGAGCGTGGCGACCTACGCTCTCCCCGGCCTCGACGGGCCGGTGGAGATCCGCGTCGACCGCTGGGGGCTGGCGCATAT
CCGCGCCGGCACCGCGCTCGACGCCTTCCGCGCGCAGGGGTTCAACGCGGCGCGGGACCGGCTCTGGCAGCTCGACCTGT
GGCGCAAGCGCGGGCTCGGCCTGCTGGCGGCGGATTTCGGACCGGGCTACCTCGCCCAGGACCGGGCCGCCCGGCTGTTC
CTCTACCGCGGCGACATGGCGGCCGAGTGGGCGGCCTACGGGCCGCAGGACACGCGGGCCATCGTCGCCGCCTTCGTGTC
GGGGATCAACGCCTACGTCGCCCTCGCCGAGGCGCGGCCCGACCTGCGTCCGCCGGAATTCGCCCTGACGGGCACGCGCC
CGGCCCTGTGGCAGCCGGAGGACGTGGTGCGCATCCGCAGCCACGCGCTGATCCGCAACGTCCTGTCCGAGGTCGCCCGC
GCGCGGGTCCTCGCCCGCGGTCGCAGCCCGGCGGACGGGCTCGCCACGGACGATCTGCGCAAGCGGATCAGCCCGCCCCA
TGAGCCGGTCGTCCCGGACGGCCTCGACGCCGCCGACTGGCCGGACGACCTCCTCGATGCCTTCCGTCTCGCCACCGCGC
CGGTCGGGTTCGGCCCGGACCGGGTGGCGGCGACCCGCGCGGAGGCCTGGGACTGGTCGAGGGTCGACGCGCACGGGGCC
GTCACGCGCGGTCCCCGCAGCGCGCCGAAGGAGCCGGCCGAGGGCTCGAACAACTGGGTGGTCGGGCCAGCCCGCACCGC
CACCGGCCGGCCGATCCTGGCGAGCGACCCGCACCGGGTCTACCTGCAGCCCTCGCTGCGCTACGCCGTCCACCTCACCG
CGCCGGGACTCGACGTGATCGGGGCCGGCGAGCCGGCCCTGCCCGGCATCTCCATCGGCCATAACGGCCACGCCGCCTTC
AGCCTCACCATTGCGCCGATCGATCAGGAGGACCTGTTCGTCTGCGAGACCGACCCGGCCGATCCCGACCGCTACCGCTC
CGGCGACGGTTGGGAACCGATCGCGCGCGTCGCGGAGCGGATCCCGGTGCGCGGCGGGCCGGACGAGACCGTGATCCTCG
GCTTCACCCGGCACGGGCCGGTCCTCCGCGAGGAGAGGGGCCGCGCCTTCGCGCTGCGGACCGTCTGGACGGAGCCCGGC
GCTGCCGCCTATCTCGGCAGCCTCGCCTATCTCGGCGCCACGACGCCCGAGGCCTTCGGCGAGGCCCTGCGCCACTGGTC
GGCGCCCTCGGTGAACCAGCTCTACGCCGACGCGGCGGGGCGGATCGCGTGGTTCATGGCCGGCAAGGCGCCGGTGCGGC
CCGGCCATGACGGGTTGCTGCCGGTGCCGGGCGACGGGCGGTACGACTGGACCGGCTTCCACGATCCCGGCGCCCTGCCC
CGGAGCGTCGATCCGGAAGCGGGCTGGCTCGCCACCGCCAACGAGATGAACCTGCCGCCGGACTATCCCGCGGAGGACCG
GAGGGTCGGGTTCGAGTGGGCCGAGCCCTGGCGGGCCCGCCGCATCCGGGCCGTCCTCGGCGGGCAGGACCGGCACAGCC
TCGCGGATTCGCGGGCGCTCCAGGGCGACGTGGTCTCCGAGCCGGCCCGGCGGCTGGCCGACCTGGTGCGCGCCCTGCCG
GCGGCGGACGATCCCGACGCCGCCGCGGCCCGGGCCGTGCTGGCCGCGTTCGACGGCGCGCTGCACCACGGCTCCGCGGC
GGCCGCCCTCATCGAGGTGGTCTGGGTCCGGCACCTGCGCCCGGCCCTGCTCGCGGCGCTCGTGCCCGATGCCGGCACGC
GCCGCCTCCTGCCGCCCGGCGACACGCAGAGCCTGCTCGAGCGGCTGGAGACCGGTCTCGACCCGGCGACGCGCGCCGGC
CTGATCAGCGACGCCCTCGGCGCCGGCCTTCGCACCTGCCGGGAGCGGATGGGCGCCGACCCGGCGCACTGGTCCTGGGG
CCGCCTGCACCACGCGCTGTTCGCGCATCCGCTGACGGCCCTGGCTACCGGATCCGGCTGGGACGTCGGCCCGCTGCCGG
TGGGCGGCGCCGCGGCATCGGTCATGCACGCGGAGTACCGGACCGACACGTTCCGGCTCACCCACGGCGCCTCGTTCCGC
ATGGTCGTGGACGTCGGGGACTGGGACCGCTCGGTCTTCATCAACGTGCCGGGCCAGTCGGGAGACCCGGGAAGTCCGCA
CTACGCCGACCTGGCCCCGGTCTGGGGGCGCCAGGACTACGTGCCGATGCTCTACGGCCGCGCGGCCGTGGACGCGGCGA
CCGAGACGGTCATCACGCTGACCCCGAGCCCCGCCTGA

Upstream 100 bases:

>100_bases
TCGGCGTCGCGGGGCGGCGGGTCGAGACCCTGCCCGACTTCATCGAGGCGTTCCAGCACGCGCTGGCCAACCCGGGACCG
CACCTCATCGAAGTGGCTCT

Downstream 100 bases:

>100_bases
CCCGGCGGCCGGGACGGATTGGGACAGGACCTTGAAGATCTTCATCGCCGGCCTCGCCACCGAGACCAACACCTTCGCGC
CGCTGCCCACCGGACGGTCG

Product: peptidase S45 penicillin amidase

Products: NA

Alternate protein names: Cephalosporin acylase II; Penicillin acylase II; Penicillin amidase II; Penicillin acylase II small subunit; Penicillin acylase II large subunit [H]

Number of amino acids: Translated: 785; Mature: 784

Protein sequence:

>785_residues
MSVATYALPGLDGPVEIRVDRWGLAHIRAGTALDAFRAQGFNAARDRLWQLDLWRKRGLGLLAADFGPGYLAQDRAARLF
LYRGDMAAEWAAYGPQDTRAIVAAFVSGINAYVALAEARPDLRPPEFALTGTRPALWQPEDVVRIRSHALIRNVLSEVAR
ARVLARGRSPADGLATDDLRKRISPPHEPVVPDGLDAADWPDDLLDAFRLATAPVGFGPDRVAATRAEAWDWSRVDAHGA
VTRGPRSAPKEPAEGSNNWVVGPARTATGRPILASDPHRVYLQPSLRYAVHLTAPGLDVIGAGEPALPGISIGHNGHAAF
SLTIAPIDQEDLFVCETDPADPDRYRSGDGWEPIARVAERIPVRGGPDETVILGFTRHGPVLREERGRAFALRTVWTEPG
AAAYLGSLAYLGATTPEAFGEALRHWSAPSVNQLYADAAGRIAWFMAGKAPVRPGHDGLLPVPGDGRYDWTGFHDPGALP
RSVDPEAGWLATANEMNLPPDYPAEDRRVGFEWAEPWRARRIRAVLGGQDRHSLADSRALQGDVVSEPARRLADLVRALP
AADDPDAAAARAVLAAFDGALHHGSAAAALIEVVWVRHLRPALLAALVPDAGTRRLLPPGDTQSLLERLETGLDPATRAG
LISDALGAGLRTCRERMGADPAHWSWGRLHHALFAHPLTALATGSGWDVGPLPVGGAAASVMHAEYRTDTFRLTHGASFR
MVVDVGDWDRSVFINVPGQSGDPGSPHYADLAPVWGRQDYVPMLYGRAAVDAATETVITLTPSPA

Sequences:

>Translated_785_residues
MSVATYALPGLDGPVEIRVDRWGLAHIRAGTALDAFRAQGFNAARDRLWQLDLWRKRGLGLLAADFGPGYLAQDRAARLF
LYRGDMAAEWAAYGPQDTRAIVAAFVSGINAYVALAEARPDLRPPEFALTGTRPALWQPEDVVRIRSHALIRNVLSEVAR
ARVLARGRSPADGLATDDLRKRISPPHEPVVPDGLDAADWPDDLLDAFRLATAPVGFGPDRVAATRAEAWDWSRVDAHGA
VTRGPRSAPKEPAEGSNNWVVGPARTATGRPILASDPHRVYLQPSLRYAVHLTAPGLDVIGAGEPALPGISIGHNGHAAF
SLTIAPIDQEDLFVCETDPADPDRYRSGDGWEPIARVAERIPVRGGPDETVILGFTRHGPVLREERGRAFALRTVWTEPG
AAAYLGSLAYLGATTPEAFGEALRHWSAPSVNQLYADAAGRIAWFMAGKAPVRPGHDGLLPVPGDGRYDWTGFHDPGALP
RSVDPEAGWLATANEMNLPPDYPAEDRRVGFEWAEPWRARRIRAVLGGQDRHSLADSRALQGDVVSEPARRLADLVRALP
AADDPDAAAARAVLAAFDGALHHGSAAAALIEVVWVRHLRPALLAALVPDAGTRRLLPPGDTQSLLERLETGLDPATRAG
LISDALGAGLRTCRERMGADPAHWSWGRLHHALFAHPLTALATGSGWDVGPLPVGGAAASVMHAEYRTDTFRLTHGASFR
MVVDVGDWDRSVFINVPGQSGDPGSPHYADLAPVWGRQDYVPMLYGRAAVDAATETVITLTPSPA
>Mature_784_residues
SVATYALPGLDGPVEIRVDRWGLAHIRAGTALDAFRAQGFNAARDRLWQLDLWRKRGLGLLAADFGPGYLAQDRAARLFL
YRGDMAAEWAAYGPQDTRAIVAAFVSGINAYVALAEARPDLRPPEFALTGTRPALWQPEDVVRIRSHALIRNVLSEVARA
RVLARGRSPADGLATDDLRKRISPPHEPVVPDGLDAADWPDDLLDAFRLATAPVGFGPDRVAATRAEAWDWSRVDAHGAV
TRGPRSAPKEPAEGSNNWVVGPARTATGRPILASDPHRVYLQPSLRYAVHLTAPGLDVIGAGEPALPGISIGHNGHAAFS
LTIAPIDQEDLFVCETDPADPDRYRSGDGWEPIARVAERIPVRGGPDETVILGFTRHGPVLREERGRAFALRTVWTEPGA
AAYLGSLAYLGATTPEAFGEALRHWSAPSVNQLYADAAGRIAWFMAGKAPVRPGHDGLLPVPGDGRYDWTGFHDPGALPR
SVDPEAGWLATANEMNLPPDYPAEDRRVGFEWAEPWRARRIRAVLGGQDRHSLADSRALQGDVVSEPARRLADLVRALPA
ADDPDAAAARAVLAAFDGALHHGSAAAALIEVVWVRHLRPALLAALVPDAGTRRLLPPGDTQSLLERLETGLDPATRAGL
ISDALGAGLRTCRERMGADPAHWSWGRLHHALFAHPLTALATGSGWDVGPLPVGGAAASVMHAEYRTDTFRLTHGASFRM
VVDVGDWDRSVFINVPGQSGDPGSPHYADLAPVWGRQDYVPMLYGRAAVDAATETVITLTPSPA

Specific function: Unknown

COG id: COG2366

COG function: function code R; Protein related to penicillin acylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S45 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014395
- InterPro:   IPR002692 [H]

Pfam domain/function: PF01804 Penicil_amidase [H]

EC number: =3.5.1.11 [H]

Molecular weight: Translated: 84298; Mature: 84166

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVATYALPGLDGPVEIRVDRWGLAHIRAGTALDAFRAQGFNAARDRLWQLDLWRKRGLG
CCCCEEECCCCCCCEEEEEECCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCE
LLAADFGPGYLAQDRAARLFLYRGDMAAEWAAYGPQDTRAIVAAFVSGINAYVALAEARP
EEEECCCCCCCCCCCCEEEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHEEEEECCCC
DLRPPEFALTGTRPALWQPEDVVRIRSHALIRNVLSEVARARVLARGRSPADGLATDDLR
CCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
KRISPPHEPVVPDGLDAADWPDDLLDAFRLATAPVGFGPDRVAATRAEAWDWSRVDAHGA
HHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCC
VTRGPRSAPKEPAEGSNNWVVGPARTATGRPILASDPHRVYLQPSLRYAVHLTAPGLDVI
CCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEECCCCEEEECCCCEEEEEEECCCCEEE
GAGEPALPGISIGHNGHAAFSLTIAPIDQEDLFVCETDPADPDRYRSGDGWEPIARVAER
ECCCCCCCCEEECCCCCEEEEEEEEECCCCCEEEEECCCCCHHHCCCCCCCCHHHHHHHH
IPVRGGPDETVILGFTRHGPVLREERGRAFALRTVWTEPGAAAYLGSLAYLGATTPEAFG
CCCCCCCCCEEEEEEECCCCCHHHCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCHHHHH
EALRHWSAPSVNQLYADAAGRIAWFMAGKAPVRPGHDGLLPVPGDGRYDWTGFHDPGALP
HHHHHCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCC
RSVDPEAGWLATANEMNLPPDYPAEDRRVGFEWAEPWRARRIRAVLGGQDRHSLADSRAL
CCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHCCCHHHHHHHHHHH
QGDVVSEPARRLADLVRALPAADDPDAAAARAVLAAFDGALHHGSAAAALIEVVWVRHLR
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
PALLAALVPDAGTRRLLPPGDTQSLLERLETGLDPATRAGLISDALGAGLRTCRERMGAD
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PAHWSWGRLHHALFAHPLTALATGSGWDVGPLPVGGAAASVMHAEYRTDTFRLTHGASFR
CCCCCHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCEE
MVVDVGDWDRSVFINVPGQSGDPGSPHYADLAPVWGRQDYVPMLYGRAAVDAATETVITL
EEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCHHHHHCCCCEEEEE
TPSPA
CCCCC
>Mature Secondary Structure 
SVATYALPGLDGPVEIRVDRWGLAHIRAGTALDAFRAQGFNAARDRLWQLDLWRKRGLG
CCCEEECCCCCCCEEEEEECCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCE
LLAADFGPGYLAQDRAARLFLYRGDMAAEWAAYGPQDTRAIVAAFVSGINAYVALAEARP
EEEECCCCCCCCCCCCEEEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHEEEEECCCC
DLRPPEFALTGTRPALWQPEDVVRIRSHALIRNVLSEVARARVLARGRSPADGLATDDLR
CCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
KRISPPHEPVVPDGLDAADWPDDLLDAFRLATAPVGFGPDRVAATRAEAWDWSRVDAHGA
HHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCC
VTRGPRSAPKEPAEGSNNWVVGPARTATGRPILASDPHRVYLQPSLRYAVHLTAPGLDVI
CCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEECCCCEEEECCCCEEEEEEECCCCEEE
GAGEPALPGISIGHNGHAAFSLTIAPIDQEDLFVCETDPADPDRYRSGDGWEPIARVAER
ECCCCCCCCEEECCCCCEEEEEEEEECCCCCEEEEECCCCCHHHCCCCCCCCHHHHHHHH
IPVRGGPDETVILGFTRHGPVLREERGRAFALRTVWTEPGAAAYLGSLAYLGATTPEAFG
CCCCCCCCCEEEEEEECCCCCHHHCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCHHHHH
EALRHWSAPSVNQLYADAAGRIAWFMAGKAPVRPGHDGLLPVPGDGRYDWTGFHDPGALP
HHHHHCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCC
RSVDPEAGWLATANEMNLPPDYPAEDRRVGFEWAEPWRARRIRAVLGGQDRHSLADSRAL
CCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHCCCHHHHHHHHHHH
QGDVVSEPARRLADLVRALPAADDPDAAAARAVLAAFDGALHHGSAAAALIEVVWVRHLR
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
PALLAALVPDAGTRRLLPPGDTQSLLERLETGLDPATRAGLISDALGAGLRTCRERMGAD
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PAHWSWGRLHHALFAHPLTALATGSGWDVGPLPVGGAAASVMHAEYRTDTFRLTHGASFR
CCCCCHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCEE
MVVDVGDWDRSVFINVPGQSGDPGSPHYADLAPVWGRQDYVPMLYGRAAVDAATETVITL
EEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCHHHHHCCCCEEEEE
TPSPA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3680178 [H]