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The map label for this gene is cpg2 [H]

Identifier: 170747329

GI number: 170747329

Start: 937014

End: 938180

Strand: Reverse

Name: cpg2 [H]

Synonym: Mrad2831_0896

Alternate gene names: 170747329

Gene position: 938180-937014 (Counterclockwise)

Preceding gene: 170747330

Following gene: 170747326

Centisome position: 15.44

GC content: 75.24

Gene sequence:

>1167_bases
ATGATCCCGGAGATGATCCCGGAGATGATCCCGGACCTGCGCTTCGACGCGCGCGACATCCTCGCGACCCTGGAGCCCTG
GGTCCTGTGCGAGAGCCCGACCCACGACGCGGCGGCGGTCAACCGCATGATGGGCGTGGCCGCCCGCGATCTCGCGCTCC
TCGGGGCCACCGTCGAGACGATCCCGGGCCGCATGGGCCTGAGCGACTGCGTCCGCGCCCGGTTCCCGCACCGGGACCGC
GACGCGCCCGGCATCCTGGTGCTCGGCCACCTCGACACGGTGCATCCGGTCGGCACCCTCGGCAGCCTGCCCTGGCGGAT
CGAGGGCGACCGCGCCTACGGTCCCGGCATCCTCGACATGAAGGGCGGCAACGTCGTCGCGCTGGCGGCGATCCGCGCCC
TGGCGGCGGCCGGGATCGAGACGCCGCTGCCGGTGACCGTCCTGTTCACCGGCGACGAGGAGGTCGGCAGCCCCTCCACC
CGCGACCTGATCGAGGCGGAGGCCGCCCGCCACGCCTTCGTGCTGGTGCCCGAACCCGGCCAGCCCGAGAACGGGGTCGT
CACCGGGCGCTACGCCATCGCCCGCTTCGAGCTCGAGGCCCTGGGCCGCCCGAGCCACGCCGGCGCCTCGCCCCACGAGG
GGCGCTCGGCGATCCGCGCGATGGCGCGGAAGATCCTCGCCATCGACGCGCTGTCGGATGCCGACTGCACCGTCTCGACC
GGGGTCGTCTCGGGCGGGCAGTGGGTGAACTGCGTCCCGACCGTCTGCCGCGGGCAGGCGCTCAGCATGGCGAAGCGGCA
GGCCGACCTCGACCGCGGCGTCGCGCGGATGCTGGCCCTGTCGGGCGAGGAGGACGGCGTCCGCTTCACCGTGACCCGGG
GCGTGACCCGGCCGGTCTGGGAGCCGGATGCCGGCTGCATGGCGCTCTACGAGCGGGCGCGCGCGCTGAGCGAGGCGCTC
GGGCAGCCCCTGCCGCATCGCAGCGCCGGCGGCGGCTCGGACGGCAACTTCACCGGCGCCAACGGCATCCCGACCCTCGA
CGGGCTCGGGCCTCTGGGCCAGGGCTACCACACCCTGGAGGAGCACGTGCTGATCGAGAGCCTGCCGCGGCGGGCGCGGC
TGTTCGCGGCCCTGCTCGCCAGCCTCGGCGCCGCCGGCCGGGCGTGA

Upstream 100 bases:

>100_bases
CGGGCGCCGTCCCGCCGGATTACGGCGCGATCCCCTACACCAAGCGGTCCGGCCTCTACTGGCCGCGGGTCGCCGATCCG
TTCGCCGAGGAGAAAGCCCG

Downstream 100 bases:

>100_bases
GCCCGGCCGCGCCGCGGTCAGGCGCGACCCCGGCCGAGGGCCGCGACCGCCAGCGCGCCCAGGAGCCCCCCGGCCGTGCC
GCCGCCGAAGAAGCCCGCCA

Product: carboxypeptidase

Products: NA

Alternate protein names: CPDG2; Folate hydrolase G2; Glutamate carboxypeptidase; Pteroylmonoglutamic acid hydrolase G2; Glucarpidase [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MIPEMIPEMIPDLRFDARDILATLEPWVLCESPTHDAAAVNRMMGVAARDLALLGATVETIPGRMGLSDCVRARFPHRDR
DAPGILVLGHLDTVHPVGTLGSLPWRIEGDRAYGPGILDMKGGNVVALAAIRALAAAGIETPLPVTVLFTGDEEVGSPST
RDLIEAEAARHAFVLVPEPGQPENGVVTGRYAIARFELEALGRPSHAGASPHEGRSAIRAMARKILAIDALSDADCTVST
GVVSGGQWVNCVPTVCRGQALSMAKRQADLDRGVARMLALSGEEDGVRFTVTRGVTRPVWEPDAGCMALYERARALSEAL
GQPLPHRSAGGGSDGNFTGANGIPTLDGLGPLGQGYHTLEEHVLIESLPRRARLFAALLASLGAAGRA

Sequences:

>Translated_388_residues
MIPEMIPEMIPDLRFDARDILATLEPWVLCESPTHDAAAVNRMMGVAARDLALLGATVETIPGRMGLSDCVRARFPHRDR
DAPGILVLGHLDTVHPVGTLGSLPWRIEGDRAYGPGILDMKGGNVVALAAIRALAAAGIETPLPVTVLFTGDEEVGSPST
RDLIEAEAARHAFVLVPEPGQPENGVVTGRYAIARFELEALGRPSHAGASPHEGRSAIRAMARKILAIDALSDADCTVST
GVVSGGQWVNCVPTVCRGQALSMAKRQADLDRGVARMLALSGEEDGVRFTVTRGVTRPVWEPDAGCMALYERARALSEAL
GQPLPHRSAGGGSDGNFTGANGIPTLDGLGPLGQGYHTLEEHVLIESLPRRARLFAALLASLGAAGRA
>Mature_388_residues
MIPEMIPEMIPDLRFDARDILATLEPWVLCESPTHDAAAVNRMMGVAARDLALLGATVETIPGRMGLSDCVRARFPHRDR
DAPGILVLGHLDTVHPVGTLGSLPWRIEGDRAYGPGILDMKGGNVVALAAIRALAAAGIETPLPVTVLFTGDEEVGSPST
RDLIEAEAARHAFVLVPEPGQPENGVVTGRYAIARFELEALGRPSHAGASPHEGRSAIRAMARKILAIDALSDADCTVST
GVVSGGQWVNCVPTVCRGQALSMAKRQADLDRGVARMLALSGEEDGVRFTVTRGVTRPVWEPDAGCMALYERARALSEAL
GQPLPHRSAGGGSDGNFTGANGIPTLDGLGPLGQGYHTLEEHVLIESLPRRARLFAALLASLGAAGRA

Specific function: Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate. This enzyme has a broad specificity [H]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR017150
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.17.11 [H]

Molecular weight: Translated: 40846; Mature: 40846

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPEMIPEMIPDLRFDARDILATLEPWVLCESPTHDAAAVNRMMGVAARDLALLGATVET
CCHHHHHHHHCCCCCCHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IPGRMGLSDCVRARFPHRDRDAPGILVLGHLDTVHPVGTLGSLPWRIEGDRAYGPGILDM
CCCCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCEEEE
KGGNVVALAAIRALAAAGIETPLPVTVLFTGDEEVGSPSTRDLIEAEAARHAFVLVPEPG
CCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCEEEEECCCC
QPENGVVTGRYAIARFELEALGRPSHAGASPHEGRSAIRAMARKILAIDALSDADCTVST
CCCCCEEECEEEEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEC
GVVSGGQWVNCVPTVCRGQALSMAKRQADLDRGVARMLALSGEEDGVRFTVTRGVTRPVW
CCCCCCCCEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
EPDAGCMALYERARALSEALGQPLPHRSAGGGSDGNFTGANGIPTLDGLGPLGQGYHTLE
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
EHVLIESLPRRARLFAALLASLGAAGRA
HHHHHHHCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIPEMIPEMIPDLRFDARDILATLEPWVLCESPTHDAAAVNRMMGVAARDLALLGATVET
CCHHHHHHHHCCCCCCHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IPGRMGLSDCVRARFPHRDRDAPGILVLGHLDTVHPVGTLGSLPWRIEGDRAYGPGILDM
CCCCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCEEEE
KGGNVVALAAIRALAAAGIETPLPVTVLFTGDEEVGSPSTRDLIEAEAARHAFVLVPEPG
CCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCEEEEECCCC
QPENGVVTGRYAIARFELEALGRPSHAGASPHEGRSAIRAMARKILAIDALSDADCTVST
CCCCCEEECEEEEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEC
GVVSGGQWVNCVPTVCRGQALSMAKRQADLDRGVARMLALSGEEDGVRFTVTRGVTRPVW
CCCCCCCCEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
EPDAGCMALYERARALSEALGQPLPHRSAGGGSDGNFTGANGIPTLDGLGPLGQGYHTLE
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHH
EHVLIESLPRRARLFAALLASLGAAGRA
HHHHHHHCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6396165; 3838935; 9083113 [H]