Click here to switch to the map view.

The map label for this gene is ppaX [H]

Identifier: 170747287

GI number: 170747287

Start: 894701

End: 895366

Strand: Reverse

Name: ppaX [H]

Synonym: Mrad2831_0854

Alternate gene names: 170747287

Gene position: 895366-894701 (Counterclockwise)

Preceding gene: 170747288

Following gene: 170747286

Centisome position: 14.73

GC content: 73.72

Gene sequence:

>666_bases
ATGAGGCTCGTCGTCTTCGACGTCGACGGCACCCTCGTCGACAGCCAGCACCTGATTGTGGCGGCCCAGGAGGTGGCTTT
CGCGGAGAACGGTCTGCCGGCGCCGGGGCGGCGGGAGGCCCTGTCGGTGGTCGGCCTGTCGCTGCCGCAGGCCTTCCGGC
GCCTGGTCGGCGAGGACGGCCCGGTCGCGGAACTCTCGGAGAGCTACAAGCAGGCCTACAACCGCCTGCGGCTCGACCCC
GCGCACGAGGAGCCCCTGTTCCCCGGCATGGCCGACCTGCTCACCCGGCTGCGCGGGCGCTCCGACGTGCTGATCGGCCT
CGCCACCGGGAAGTCGCGGCGCGGTGTCGACCGGCTGATCGCGCATCACGGCTGGGCGGGCTGGTTCGCCACCACCCAGA
GCGCCGACGACGCGCCGTCGAAGCCGGATCCGACCATGCTGCAGCAGGCGATCCGCGAGGCCGGCTGCGAGCCCGAGGCC
ACCGTGATGGTCGGCGACACCACCTTCGACATCGCCATGGGCGTGGCGGCCGGCGCCACCGCGATCGGGGTCGCCTGGGG
CTACCATCCTCCGGACGCGCTCTACGGGGCCGGGGCCGTGACGGTGGTTCCGAGCGCCGCGGCGCTGGAGGCGCTGCTTC
TGGAGCGGCTCGCGACGGGCGCCTGA

Upstream 100 bases:

>100_bases
CCCGCCGCGGCCGCGCCGGCACAGCCGGGCCGGAAGCCGTGACGGAGACCAGGATCTACCCACCCGCGCCGTCGGGGCGG
CTCTCGGCGCGCCGGCCGCG

Downstream 100 bases:

>100_bases
TCGCGAGAGGCTCGCGCGCGGGGCCGGAAGCGCCTATCTCGCCTCCATGAGCGATCAGACGACAGACTGGCTCGGGCAGC
CGAGCGACGGTGAGAAGCCC

Product: HAD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MRLVVFDVDGTLVDSQHLIVAAQEVAFAENGLPAPGRREALSVVGLSLPQAFRRLVGEDGPVAELSESYKQAYNRLRLDP
AHEEPLFPGMADLLTRLRGRSDVLIGLATGKSRRGVDRLIAHHGWAGWFATTQSADDAPSKPDPTMLQQAIREAGCEPEA
TVMVGDTTFDIAMGVAAGATAIGVAWGYHPPDALYGAGAVTVVPSAAALEALLLERLATGA

Sequences:

>Translated_221_residues
MRLVVFDVDGTLVDSQHLIVAAQEVAFAENGLPAPGRREALSVVGLSLPQAFRRLVGEDGPVAELSESYKQAYNRLRLDP
AHEEPLFPGMADLLTRLRGRSDVLIGLATGKSRRGVDRLIAHHGWAGWFATTQSADDAPSKPDPTMLQQAIREAGCEPEA
TVMVGDTTFDIAMGVAAGATAIGVAWGYHPPDALYGAGAVTVVPSAAALEALLLERLATGA
>Mature_221_residues
MRLVVFDVDGTLVDSQHLIVAAQEVAFAENGLPAPGRREALSVVGLSLPQAFRRLVGEDGPVAELSESYKQAYNRLRLDP
AHEEPLFPGMADLLTRLRGRSDVLIGLATGKSRRGVDRLIAHHGWAGWFATTQSADDAPSKPDPTMLQQAIREAGCEPEA
TVMVGDTTFDIAMGVAAGATAIGVAWGYHPPDALYGAGAVTVVPSAAALEALLLERLATGA

Specific function: Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool [H]

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. PpaX family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=226, Percent_Identity=28.7610619469027, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 23278; Mature: 23278

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLVVFDVDGTLVDSQHLIVAAQEVAFAENGLPAPGRREALSVVGLSLPQAFRRLVGEDG
CEEEEEECCCEEECCCEEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
PVAELSESYKQAYNRLRLDPAHEEPLFPGMADLLTRLRGRSDVLIGLATGKSRRGVDRLI
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCHHHHH
AHHGWAGWFATTQSADDAPSKPDPTMLQQAIREAGCEPEATVMVGDTTFDIAMGVAAGAT
HHCCCHHHEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHCHH
AIGVAWGYHPPDALYGAGAVTVVPSAAALEALLLERLATGA
HHHHCCCCCCCHHHHCCCCEEECCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLVVFDVDGTLVDSQHLIVAAQEVAFAENGLPAPGRREALSVVGLSLPQAFRRLVGEDG
CEEEEEECCCEEECCCEEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
PVAELSESYKQAYNRLRLDPAHEEPLFPGMADLLTRLRGRSDVLIGLATGKSRRGVDRLI
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCHHHHH
AHHGWAGWFATTQSADDAPSKPDPTMLQQAIREAGCEPEATVMVGDTTFDIAMGVAAGAT
HHCCCHHHEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHCHH
AIGVAWGYHPPDALYGAGAVTVVPSAAALEALLLERLATGA
HHHHCCCCCCCHHHHCCCCEEECCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]