Click here to switch to the map view.

The map label for this gene is irgA [H]

Identifier: 170684240

GI number: 170684240

Start: 3214175

End: 3216262

Strand: Reverse

Name: irgA [H]

Synonym: EcSMS35_3128

Alternate gene names: 170684240

Gene position: 3216262-3214175 (Counterclockwise)

Preceding gene: 170681851

Following gene: 170680348

Centisome position: 63.46

GC content: 51.68

Gene sequence:

>2088_bases
ATGCGAGTAACCACTCTGGCTTCAGTAGCCATCCCTTGTCTCGGGTTTTCAGTCAGCAGTATGGCTGCGGAAGATGTGAT
GGTAGTCACGGCGTCTGGCTATGAAAAAAAATTAACCAGTGCAGCTGCGAGTGTTTCAGTGATCAGCCAGGAGGATTTGC
GATCCAGCCAGTATCATGATCTGGGGGAGGCACTGAGATCCGTAGAGGGGGTGGATGTTGAAAGCGGTACGGGTAAAACA
GGTGGGCTGGAAATCAGCATCCGCGGAATGCCTGCCAGTTATACGCTGATACTGATCGATGGTGTCCGTCAGGGCGGGAG
CAGTGACGTAACCCCAAACGGTTATGCTGCCATGAATACGGGTTTTATGCCACCTCTGGCCGCCATCGAACGTATTGAGA
TTATCAGGGGCCCCATGTCCACTCTGTACGGCTCTGATGCCATGGGGGGCGTGGTGAATATCATCACCAAAAAGAATGCA
GACAAATGGCGCTCTTCGGTTAATGCCGGGCTGAACCTGCAGGAAAGTAACAAATGGGGGAACAGCAGCCAGTTTAATTT
CTGGAGCAGCGGTCCCCTTGTGGATGATTCACTCAGCCTTCAGGTACGTGGCAGCACACAGCAGCGTCAGGGCTCATCGG
TCACATCACTGAGCGACACCTCAGCTACGCGTATCCCTTATCCCACGGAATCACAGAATTATAATGCAGGTGGTCGTCTT
GACTGGAAAGCGACGGACAAGGATGTACTCTGGATTGATATGGATATCGCCCGGCAGCGTTATGATAACCGAGATGGCCA
GCTGGGCAGTCTGACGGGCGGTTATGATCGCACCCTGCGCTATGAGCGTAATAAAATTTCAGCAGGCTATGATCATACAT
TCACCTTCGGAGCCTGGAAGTCATCCCTGAACTGGAATGAGACGGAAAATAAAGGCCGTCAGCTTGTACGTAGCGTACTG
CAGCGTGATAAATGGGGGCTTGCCGGCCAGCCGAGGGAGCTTAAGGAGTCGAATCTTATCCTGAGCTCATTACTGTTTGC
ACCTCTGGGGGAATCACACAAGGTTACCGTCGGTGGTGAGTATCAGAACTCCTCCATGAAAGACGGGGTTGTTCTCGCCA
GTACTGGTGAAACCTTCCGTCAGAAAAGCTGGTCGGCATTTGTTGAGGATGAGTGGTATATCACGGATGCATTTGCACTG
ACTGCGGGTAGCCGCTATGAACGCTATGAGGTGTTCGGAGGACACTTCAGTCCCCGGGCATATATGGTCTGGGATGTGAC
TGATGCGTGGACGCTGAAAGGTGGGGTGACCACGGGATATAAGGCGCCCAGCATGGGGCAGTTACATAAGGGGATCAGCG
GTGTGTCCGGTCAGGGGCGTACGAATCTTCTCGGTAACCCGGACCTGAAGCCGGAGGAGAGTGTCAGTTATGAAGCGGGC
GTGTATTACGATAATCATGCCGGTCTGAACGCCAATATCACGGGCTTTATGACAGAATTCTCCAACAAGATCGTATCTTA
TTCCATTGATGATAATACCCGCAGCTACACAAACAGCGGAAAGGCCAGGACTCAGGGCGTGGAATTTGCCGGCACACTGC
CTCTGTTGTCAGAGGATGTGACTCTGTCTCTGAATTATACCTGGACGCAGAGTGAACAACGGGATGGGGATAATAAAGGT
GCACCACTGAGTTACACCCCTGAGCATATGGTGAATGCGAAACTGAACTGGCAGATTACTGAAGAGGTGACATCATGGCT
GGGTGCCCGTTACCGCGGGAAAACGCCACGTTTCACCCAGAATTATTCGTCACTCTCAGCTGTACAGAAGAAAGTGTATG
ATGAGAAAGGTGAATATCTGAAAGCCTGGACGGTACTGGATGCGGGCATGTCGTGGAAAGTGACGGATGCACTGATGCTG
AATGCAGCGGTGAATAATGTGCTTAACAAGGATTACAGTGACGTAAGTCTGTATCGTGCCGGCAGTGGTACGCTTTATGC
GGGTGATTACTTCCAGACGGGGGCATCGACAACGGGTTATGTGATACCTGAGAGAAATTACTGGATGTCGCTGAACTATC
AGTTCTGA

Upstream 100 bases:

>100_bases
TAATTTTTTACTTTTTTATGTAAAAACCAAAAGCAAATCATTCTCATTATCTCTTGCGTTTGTTTATCTTCTCTCTGATT
AATATAATCGGAGAGAAGAT

Downstream 100 bases:

>100_bases
TAACAACAAACCCGATATAACGCATTATAATACGTAAAGATGCTGCCTCTGTCACCTGAGGGCAGTGGCAGCAACACACG
ATGCAGGTGTTTGATCACCA

Product: bifunctional enterobactin receptor/adhesin protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 695; Mature: 695

Protein sequence:

>695_residues
MRVTTLASVAIPCLGFSVSSMAAEDVMVVTASGYEKKLTSAAASVSVISQEDLRSSQYHDLGEALRSVEGVDVESGTGKT
GGLEISIRGMPASYTLILIDGVRQGGSSDVTPNGYAAMNTGFMPPLAAIERIEIIRGPMSTLYGSDAMGGVVNIITKKNA
DKWRSSVNAGLNLQESNKWGNSSQFNFWSSGPLVDDSLSLQVRGSTQQRQGSSVTSLSDTSATRIPYPTESQNYNAGGRL
DWKATDKDVLWIDMDIARQRYDNRDGQLGSLTGGYDRTLRYERNKISAGYDHTFTFGAWKSSLNWNETENKGRQLVRSVL
QRDKWGLAGQPRELKESNLILSSLLFAPLGESHKVTVGGEYQNSSMKDGVVLASTGETFRQKSWSAFVEDEWYITDAFAL
TAGSRYERYEVFGGHFSPRAYMVWDVTDAWTLKGGVTTGYKAPSMGQLHKGISGVSGQGRTNLLGNPDLKPEESVSYEAG
VYYDNHAGLNANITGFMTEFSNKIVSYSIDDNTRSYTNSGKARTQGVEFAGTLPLLSEDVTLSLNYTWTQSEQRDGDNKG
APLSYTPEHMVNAKLNWQITEEVTSWLGARYRGKTPRFTQNYSSLSAVQKKVYDEKGEYLKAWTVLDAGMSWKVTDALML
NAAVNNVLNKDYSDVSLYRAGSGTLYAGDYFQTGASTTGYVIPERNYWMSLNYQF

Sequences:

>Translated_695_residues
MRVTTLASVAIPCLGFSVSSMAAEDVMVVTASGYEKKLTSAAASVSVISQEDLRSSQYHDLGEALRSVEGVDVESGTGKT
GGLEISIRGMPASYTLILIDGVRQGGSSDVTPNGYAAMNTGFMPPLAAIERIEIIRGPMSTLYGSDAMGGVVNIITKKNA
DKWRSSVNAGLNLQESNKWGNSSQFNFWSSGPLVDDSLSLQVRGSTQQRQGSSVTSLSDTSATRIPYPTESQNYNAGGRL
DWKATDKDVLWIDMDIARQRYDNRDGQLGSLTGGYDRTLRYERNKISAGYDHTFTFGAWKSSLNWNETENKGRQLVRSVL
QRDKWGLAGQPRELKESNLILSSLLFAPLGESHKVTVGGEYQNSSMKDGVVLASTGETFRQKSWSAFVEDEWYITDAFAL
TAGSRYERYEVFGGHFSPRAYMVWDVTDAWTLKGGVTTGYKAPSMGQLHKGISGVSGQGRTNLLGNPDLKPEESVSYEAG
VYYDNHAGLNANITGFMTEFSNKIVSYSIDDNTRSYTNSGKARTQGVEFAGTLPLLSEDVTLSLNYTWTQSEQRDGDNKG
APLSYTPEHMVNAKLNWQITEEVTSWLGARYRGKTPRFTQNYSSLSAVQKKVYDEKGEYLKAWTVLDAGMSWKVTDALML
NAAVNNVLNKDYSDVSLYRAGSGTLYAGDYFQTGASTTGYVIPERNYWMSLNYQF
>Mature_695_residues
MRVTTLASVAIPCLGFSVSSMAAEDVMVVTASGYEKKLTSAAASVSVISQEDLRSSQYHDLGEALRSVEGVDVESGTGKT
GGLEISIRGMPASYTLILIDGVRQGGSSDVTPNGYAAMNTGFMPPLAAIERIEIIRGPMSTLYGSDAMGGVVNIITKKNA
DKWRSSVNAGLNLQESNKWGNSSQFNFWSSGPLVDDSLSLQVRGSTQQRQGSSVTSLSDTSATRIPYPTESQNYNAGGRL
DWKATDKDVLWIDMDIARQRYDNRDGQLGSLTGGYDRTLRYERNKISAGYDHTFTFGAWKSSLNWNETENKGRQLVRSVL
QRDKWGLAGQPRELKESNLILSSLLFAPLGESHKVTVGGEYQNSSMKDGVVLASTGETFRQKSWSAFVEDEWYITDAFAL
TAGSRYERYEVFGGHFSPRAYMVWDVTDAWTLKGGVTTGYKAPSMGQLHKGISGVSGQGRTNLLGNPDLKPEESVSYEAG
VYYDNHAGLNANITGFMTEFSNKIVSYSIDDNTRSYTNSGKARTQGVEFAGTLPLLSEDVTLSLNYTWTQSEQRDGDNKG
APLSYTPEHMVNAKLNWQITEEVTSWLGARYRGKTPRFTQNYSSLSAVQKKVYDEKGEYLKAWTVLDAGMSWKVTDALML
NAAVNNVLNKDYSDVSLYRAGSGTLYAGDYFQTGASTTGYVIPERNYWMSLNYQF

Specific function: Involved in the initial step of iron uptake by binding ferric vibriobactin, an iron chelatin siderophore that allows V.cholerae to extract iron from the environment [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=716, Percent_Identity=31.5642458100559, Blast_Score=285, Evalue=9e-78,
Organism=Escherichia coli, GI1786798, Length=760, Percent_Identity=27.6315789473684, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1790405, Length=698, Percent_Identity=25.7879656160458, Blast_Score=157, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 76400; Mature: 76400

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVTTLASVAIPCLGFSVSSMAAEDVMVVTASGYEKKLTSAAASVSVISQEDLRSSQYHD
CCEEEHHHHHHHHCCCCHHHHCCCCEEEEEECCCHHHHHHHHHHEEEECHHHHHHHHHHH
LGEALRSVEGVDVESGTGKTGGLEISIRGMPASYTLILIDGVRQGGSSDVTPNGYAAMNT
HHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCEEECC
GFMPPLAAIERIEIIRGPMSTLYGSDAMGGVVNIITKKNADKWRSSVNAGLNLQESNKWG
CCCCHHHHHHHHHHHHCCHHHHCCCCCCCCEEEEEECCCHHHHHHHHHCCCEEECCCCCC
NSSQFNFWSSGPLVDDSLSLQVRGSTQQRQGSSVTSLSDTSATRIPYPTESQNYNAGGRL
CCCCCEEECCCCEECCCEEEEEECCCHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCEE
DWKATDKDVLWIDMDIARQRYDNRDGQLGSLTGGYDRTLRYERNKISAGYDHTFTFGAWK
EEEECCCEEEEEEHHHHHHHHCCCCCCCCCCCCCCHHEEEEECCCCCCCCCCEEEEECHH
SSLNWNETENKGRQLVRSVLQRDKWGLAGQPRELKESNLILSSLLFAPLGESHKVTVGGE
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCC
YQNSSMKDGVVLASTGETFRQKSWSAFVEDEWYITDAFALTAGSRYERYEVFGGHFSPRA
CCCCCCCCCEEEEECCHHHHHCCCCEEECCCEEEEEEEEECCCCCCEEEEEECCCCCCCE
YMVWDVTDAWTLKGGVTTGYKAPSMGQLHKGISGVSGQGRTNLLGNPDLKPEESVSYEAG
EEEEECCCCEEECCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEECC
VYYDNHAGLNANITGFMTEFSNKIVSYSIDDNTRSYTNSGKARTQGVEFAGTLPLLSEDV
EEECCCCCCCCCCEEHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEEECCCCEECCCE
TLSLNYTWTQSEQRDGDNKGAPLSYTPEHMVNAKLNWQITEEVTSWLGARYRGKTPRFTQ
EEEEEEEECCCHHCCCCCCCCCCCCCHHHHCCCEEEEEEHHHHHHHHCCCCCCCCCCCCC
NYSSLSAVQKKVYDEKGEYLKAWTVLDAGMSWKVTDALMLNAAVNNVLNKDYSDVSLYRA
CHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEHHHHHHHHHHHHHHCCCCCCEEEEEC
GSGTLYAGDYFQTGASTTGYVIPERNYWMSLNYQF
CCCCEEECCCEECCCCCCEEEEECCCEEEEEEECC
>Mature Secondary Structure
MRVTTLASVAIPCLGFSVSSMAAEDVMVVTASGYEKKLTSAAASVSVISQEDLRSSQYHD
CCEEEHHHHHHHHCCCCHHHHCCCCEEEEEECCCHHHHHHHHHHEEEECHHHHHHHHHHH
LGEALRSVEGVDVESGTGKTGGLEISIRGMPASYTLILIDGVRQGGSSDVTPNGYAAMNT
HHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCCEEECC
GFMPPLAAIERIEIIRGPMSTLYGSDAMGGVVNIITKKNADKWRSSVNAGLNLQESNKWG
CCCCHHHHHHHHHHHHCCHHHHCCCCCCCCEEEEEECCCHHHHHHHHHCCCEEECCCCCC
NSSQFNFWSSGPLVDDSLSLQVRGSTQQRQGSSVTSLSDTSATRIPYPTESQNYNAGGRL
CCCCCEEECCCCEECCCEEEEEECCCHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCEE
DWKATDKDVLWIDMDIARQRYDNRDGQLGSLTGGYDRTLRYERNKISAGYDHTFTFGAWK
EEEECCCEEEEEEHHHHHHHHCCCCCCCCCCCCCCHHEEEEECCCCCCCCCCEEEEECHH
SSLNWNETENKGRQLVRSVLQRDKWGLAGQPRELKESNLILSSLLFAPLGESHKVTVGGE
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCC
YQNSSMKDGVVLASTGETFRQKSWSAFVEDEWYITDAFALTAGSRYERYEVFGGHFSPRA
CCCCCCCCCEEEEECCHHHHHCCCCEEECCCEEEEEEEEECCCCCCEEEEEECCCCCCCE
YMVWDVTDAWTLKGGVTTGYKAPSMGQLHKGISGVSGQGRTNLLGNPDLKPEESVSYEAG
EEEEECCCCEEECCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEECC
VYYDNHAGLNANITGFMTEFSNKIVSYSIDDNTRSYTNSGKARTQGVEFAGTLPLLSEDV
EEECCCCCCCCCCEEHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEEECCCCEECCCE
TLSLNYTWTQSEQRDGDNKGAPLSYTPEHMVNAKLNWQITEEVTSWLGARYRGKTPRFTQ
EEEEEEEECCCHHCCCCCCCCCCCCCHHHHCCCEEEEEEHHHHHHHHCCCCCCCCCCCCC
NYSSLSAVQKKVYDEKGEYLKAWTVLDAGMSWKVTDALMLNAAVNNVLNKDYSDVSLYRA
CHHHHHHHHHHHHHCCCCEEEEEEEEECCCCEEEHHHHHHHHHHHHHHCCCCCCEEEEEC
GSGTLYAGDYFQTGASTTGYVIPERNYWMSLNYQF
CCCCEEECCCEECCCCCCEEEEECCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1406279; 2174861 [H]