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The map label for this gene is zur [H]

Identifier: 170683816

GI number: 170683816

Start: 4607037

End: 4607552

Strand: Reverse

Name: zur [H]

Synonym: EcSMS35_4508

Alternate gene names: 170683816

Gene position: 4607552-4607037 (Counterclockwise)

Preceding gene: 170681673

Following gene: 170682968

Centisome position: 90.91

GC content: 51.94

Gene sequence:

>516_bases
ATGGAAAAGACCACAACGCAGGAGTTATTAGCGCAGGCTGAAAAAATCTGCGCGCAGCGTAATGTGCGCCTGACCCCACA
GCGCCTGGAAGTGTTGCGCCTGATGAGTCTGCAGGATGGCGCTATCAGCGCTTATGATCTGCTTGATTTGCTGCGCGAAG
CTGAACCGCAAGCCAAGCCGCCAACGGTTTATCGCGCGCTGGATTTTCTGCTTGAGCAAGGTTTTGTGCATAAGGTGGAA
TCCACCAACAGTTATGTGCTCTGTCATCTGTTCGACCAGCCCACGCATACGTCAGCCATGTTTATTTGCGATCGCTGCGG
CGCAGTGAAAGAAGAATGTGCAGAAGGCGTGGAAGACATTATGCATACGCTGGCGGCAAAAATGGGGTTTGCCCTGCGGC
ATAATGTGATTGAAGCACATGGACTCTGTGCGGCATGCGTGGAAGTGGAAGCGTGTCGTCATCCTGAACAGTGCCAGCAT
GATCACTCTGTACAGGTGAAAAAGAAATCACGTTAA

Upstream 100 bases:

>100_bases
AAACAGAAAATCAACATTACGGCAACAATAAGGGTTCTCGGTGTTTTTCCTGGAACATGGTAAAGTAAGGACATTCTTAA
CCCCCACTTTGAGGTGCCCG

Downstream 100 bases:

>100_bases
GAGGGCGTACATCCTTGTACACGTCGGGCAGGAGGGATTAATTACCAGCGGTAATCATGGCGTTTTTCCCAACTATCAAC
CTCTTTTTCTGCCTGATCTT

Product: zinc uptake transcriptional repressor

Products: NA

Alternate protein names: Zinc uptake regulator [H]

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MEKTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVE
STNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEACRHPEQCQH
DHSVQVKKKSR

Sequences:

>Translated_171_residues
MEKTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVE
STNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEACRHPEQCQH
DHSVQVKKKSR
>Mature_171_residues
MEKTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVE
STNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEACRHPEQCQH
DHSVQVKKKSR

Specific function: Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes (znuACB) [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI87082363, Length=171, Percent_Identity=99.4152046783626, Blast_Score=350, Evalue=2e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 19244; Mature: 19244

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKP
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCC
PTVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDI
CHHHHHHHHHHHCCHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHH
MHTLAAKMGFALRHNVIEAHGLCAACVEVEACRHPEQCQHDHSVQVKKKSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MEKTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKP
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCC
PTVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDI
CHHHHHHHHHHHCCHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHH
MHTLAAKMGFALRHNVIEAHGLCAACVEVEACRHPEQCQHDHSVQVKKKSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 9680209 [H]