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The map label for this gene is ydhB [H]

Identifier: 170683410

GI number: 170683410

Start: 4296600

End: 4297496

Strand: Reverse

Name: ydhB [H]

Synonym: EcSMS35_4196

Alternate gene names: 170683410

Gene position: 4297496-4296600 (Counterclockwise)

Preceding gene: 170680197

Following gene: 170682422

Centisome position: 84.79

GC content: 46.71

Gene sequence:

>897_bases
ATGTTCATCTCAGACGAAACGCTTCGTGTTATTCATCTGGTCGCCAGACACCAGAGCATTACCACCGCAGCCGAGCAGTT
AAATAAAGTCCCTTCCGCCATCAGTTACACCATCAAGAAAGCGGAAGAGAGCCTGGGCGTTGAACTGTTCATTCGTAAGG
GACGCTATATTGAATTATCGCCAGCGGGAAGTTACTTCATCGAACATAGCAAAACTATTCTTGGCGACCTGGAAGCATTA
AAGCGCAACACAGTGCTGATTCACGATGGTATTGAGCGTGAACTGACAATTGCGGTAAACAATATTATTCCTGGTGATTT
GCTGGTGGCATTTATTCGAGATTTTGAACGGCAATTCACATCAACAACACTGACGGTAGATCTTGAGGTATACAACGGCT
GCTGGGATGCGCTGTACAGTAAGCGTGCCGATCTGGTCTACGGTGCTCCTCATGCAGTGCCAAGCAGTGAAGGCATCATT
AGCGAACCGGTCGGACAAATGGAATGGGATTTTGTCGTCAGCCCACTCCACCCACTGGCAGCGAAGCGGCATCCATTAGA
AAACAGTGAATTGCGTCATTATCCAGCGGTTTGTATCCGCGATACCTCCGTTAACTTCCCCCCGATGCAAGCCTGGTTGT
TGGAAGGACAAAAACCCATTTTTGTTCCTGACTTCGCTACGGCAATCGCCTTAATAGAACAAAACGTCGGTATTGGTTAT
ATTCCACATCATCTGGCATTGCCGTTATTGAACAGCGGTAAATTGCTTAAAAAGCCAATGCGCGAACATAAACACGCCAC
CAAGTTATTTCTTGCCGCTCGTTCCGATGGTATGGGCAAAGCCTGTCAGTGGTGCATAGAATATTTAAGAAATCCGCAAT
TAATTTTCTGTTCCTGA

Upstream 100 bases:

>100_bases
GTCGGGCAAGTCAACACCGCTAATTCCTGGGTATACTCAGGCAATGATTACGGCTGAATCTGGAGAGATTCAGCCACTTT
ACCACTGACCAGGAAGCCTT

Downstream 100 bases:

>100_bases
AGATCCACATCATACCTGGCATACATAGCAAAATGGCTTCCGGTGTTGGAAGCCATTATTGTGCTGCAATTTACAATGAC
TCGTTAATACTCATCATCCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MFISDETLRVIHLVARHQSITTAAEQLNKVPSAISYTIKKAEESLGVELFIRKGRYIELSPAGSYFIEHSKTILGDLEAL
KRNTVLIHDGIERELTIAVNNIIPGDLLVAFIRDFERQFTSTTLTVDLEVYNGCWDALYSKRADLVYGAPHAVPSSEGII
SEPVGQMEWDFVVSPLHPLAAKRHPLENSELRHYPAVCIRDTSVNFPPMQAWLLEGQKPIFVPDFATAIALIEQNVGIGY
IPHHLALPLLNSGKLLKKPMREHKHATKLFLAARSDGMGKACQWCIEYLRNPQLIFCS

Sequences:

>Translated_298_residues
MFISDETLRVIHLVARHQSITTAAEQLNKVPSAISYTIKKAEESLGVELFIRKGRYIELSPAGSYFIEHSKTILGDLEAL
KRNTVLIHDGIERELTIAVNNIIPGDLLVAFIRDFERQFTSTTLTVDLEVYNGCWDALYSKRADLVYGAPHAVPSSEGII
SEPVGQMEWDFVVSPLHPLAAKRHPLENSELRHYPAVCIRDTSVNFPPMQAWLLEGQKPIFVPDFATAIALIEQNVGIGY
IPHHLALPLLNSGKLLKKPMREHKHATKLFLAARSDGMGKACQWCIEYLRNPQLIFCS
>Mature_298_residues
MFISDETLRVIHLVARHQSITTAAEQLNKVPSAISYTIKKAEESLGVELFIRKGRYIELSPAGSYFIEHSKTILGDLEAL
KRNTVLIHDGIERELTIAVNNIIPGDLLVAFIRDFERQFTSTTLTVDLEVYNGCWDALYSKRADLVYGAPHAVPSSEGII
SEPVGQMEWDFVVSPLHPLAAKRHPLENSELRHYPAVCIRDTSVNFPPMQAWLLEGQKPIFVPDFATAIALIEQNVGIGY
IPHHLALPLLNSGKLLKKPMREHKHATKLFLAARSDGMGKACQWCIEYLRNPQLIFCS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787949, Length=292, Percent_Identity=34.5890410958904, Blast_Score=195, Evalue=2e-51,
Organism=Escherichia coli, GI1786508, Length=282, Percent_Identity=34.3971631205674, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1786713, Length=279, Percent_Identity=33.6917562724014, Blast_Score=164, Evalue=5e-42,
Organism=Escherichia coli, GI87082024, Length=279, Percent_Identity=31.5412186379928, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1789492, Length=282, Percent_Identity=28.0141843971631, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI157672245, Length=168, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788706, Length=120, Percent_Identity=34.1666666666667, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33436; Mature: 33436

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFISDETLRVIHLVARHQSITTAAEQLNKVPSAISYTIKKAEESLGVELFIRKGRYIELS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCEEEEEECCCEEEEC
PAGSYFIEHSKTILGDLEALKRNTVLIHDGIERELTIAVNNIIPGDLLVAFIRDFERQFT
CCCCCHHHCCHHHHHHHHHHHCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHC
STTLTVDLEVYNGCWDALYSKRADLVYGAPHAVPSSEGIISEPVGQMEWDFVVSPLHPLA
CEEEEEEEEEHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCHHEEECCCCHHH
AKRHPLENSELRHYPAVCIRDTSVNFPPMQAWLLEGQKPIFVPDFATAIALIEQNVGIGY
HCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHCCCCCEECCHHHHHHHHHHCCCCCCC
IPHHLALPLLNSGKLLKKPMREHKHATKLFLAARSDGMGKACQWCIEYLRNPQLIFCS
CCHHHHCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHCCCCEEEEC
>Mature Secondary Structure
MFISDETLRVIHLVARHQSITTAAEQLNKVPSAISYTIKKAEESLGVELFIRKGRYIELS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCEEEEEECCCEEEEC
PAGSYFIEHSKTILGDLEALKRNTVLIHDGIERELTIAVNNIIPGDLLVAFIRDFERQFT
CCCCCHHHCCHHHHHHHHHHHCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHC
STTLTVDLEVYNGCWDALYSKRADLVYGAPHAVPSSEGIISEPVGQMEWDFVVSPLHPLA
CEEEEEEEEEHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCHHEEECCCCHHH
AKRHPLENSELRHYPAVCIRDTSVNFPPMQAWLLEGQKPIFVPDFATAIALIEQNVGIGY
HCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHCCCCCEECCHHHHHHHHHHCCCCCCC
IPHHLALPLLNSGKLLKKPMREHKHATKLFLAARSDGMGKACQWCIEYLRNPQLIFCS
CCHHHHCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]