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The map label for this gene is icc [H]

Identifier: 170683396

GI number: 170683396

Start: 3404528

End: 3405355

Strand: Reverse

Name: icc [H]

Synonym: EcSMS35_3327

Alternate gene names: 170683396

Gene position: 3405355-3404528 (Counterclockwise)

Preceding gene: 170682587

Following gene: 170684219

Centisome position: 67.19

GC content: 56.76

Gene sequence:

>828_bases
TTGGAAAGCCTGTTAACCCTTCCTCTGGCTGGTGAGGCCAGAGTCAGGATTTTACAAATTACCGACACTCACCTGTTTGC
ACAAAAGCACGAAGCCCTGTTAGGGGTAAACACCTGGGAAAGCTACCAGGCGGTGCTGGAGGCGATTCGGCCACACCAGC
ACGAATTCGACCTGATTGTCGCGACAGGTGATTTAGCGCAGGATCAATCCTCTGCGGCCTATCAGCATTTCGCTGAAGGC
ATCGCAAGTTTTCGTGCGCCCTGCGTCTGGCTGCCGGGCAACCACGATTTCCAGCCCGCGATGTACAGCGCGTTACAGGA
TGCGGGTATCTCCCCGGCGAAGCGGGTGTTTATTGGTGAGCAATGGCAAATCCTGTTGCTGGATAGCCAGGTGTTTGGCG
TGCCGCACGGTGAGCTGAGCGAGTTTCAGCTTGAGTGGCTGGAACGTAAACTGGCCGATGCGCCAGAACGCCATACGTTG
CTGCTGCTGCATCATCATCCGCTACCTGCGGGTTGTAGTTGGCTTGATCAACACAGCCTGCGTAACGCGGGCGAACTGGA
TACCGTGCTGGCGAAGTTTCCGCACGTCAAATACTTGCTGTGCGGTCATATTCATCAGGAGCTGGATCTCGACTGGAACG
GTCGCCGCTTGCTGGCAACGCCGTCGACCTGTGTGCAGTTTAAGCCGCACTGTTCTAACTTTACGCTGGACACCATCGCG
CCCGGCTGGCGTACTCTCGAGTTACATGCTGATGGCACGCTGACCACCGAGGTGCATCGCCTGGCGGACGCACGCTTCCA
ACCTGATACCGCTTCAGAAGGCTACTGA

Upstream 100 bases:

>100_bases
TCAAATTAATCAGTTTTTAGCGGACTGGTTGCGATACTGTTTAGCACATGGAGCGATGGCGATTCCGGTTTATTAGCGTC
GTGAAACCTAAGGACACCAT

Downstream 100 bases:

>100_bases
TGTCTACGCTTCTTTATTTACACGGTTTCAACAGCTCGCCGCGCTCTGCAAAAGCGAGCTTGTTAAAAAACTGGTTGGCG
GAACATCACCCTGACGTAGA

Product: cyclic 3',5'-adenosine monophosphate phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEG
IASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTL
LLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY

Sequences:

>Translated_275_residues
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEG
IASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTL
LLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
>Mature_275_residues
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEG
IASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTL
LLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY

Specific function: Affects the expression of the lacZ gene [H]

COG id: COG1409

COG function: function code R; Predicted phosphohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789410, Length=275, Percent_Identity=99.6363636363636, Blast_Score=562, Evalue=1e-162,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013622
- InterPro:   IPR004843
- ProDom:   PD587589 [H]

Pfam domain/function: PF00149 Metallophos; PF08413 Metallophos_C [H]

EC number: NA

Molecular weight: Translated: 30908; Mature: 30908

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
CCCEEEECCCCCCEEEEEEEECHHHHHHHHHHEEECCCHHHHHHHHHHHCCCCCCEEEEE
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
EECCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCHHHEEEECC
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
CEEEEEEECEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHC
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
CCCCHHHHHHHHCCCCEEHHHHHHHHHCCCCCCCCEEEECCCHHEEECCCCCCEEECCCC
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
CCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIV
CCCEEEECCCCCCEEEEEEEECHHHHHHHHHHEEECCCHHHHHHHHHHHCCCCCCEEEEE
ATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGE
EECCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCHHHEEEECC
QWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTLLLLHHHPLPAGCSWLDQHSL
CEEEEEEECEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHC
RNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
CCCCHHHHHHHHCCCCEEHHHHHHHHHCCCCCCCCEEEECCCHHEEECCCCCCEEECCCC
PGWRTLELHADGTLTTEVHRLADARFQPDTASEGY
CCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]