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The map label for this gene is ttuB [H]

Identifier: 170683353

GI number: 170683353

Start: 2424732

End: 2426060

Strand: Reverse

Name: ttuB [H]

Synonym: EcSMS35_2381

Alternate gene names: 170683353

Gene position: 2426060-2424732 (Counterclockwise)

Preceding gene: 170679991

Following gene: 170684206

Centisome position: 47.87

GC content: 40.11

Gene sequence:

>1329_bases
ATGAGCAGTCCTCAGAAAGATTTGTATGAAGCCATTTCTATTGTGAAAAGGAAGATTATTCCGTTAGCATTTATTCTGTA
TTTTTTTAACTATATGGATCGTGTTAACATCGGATTTGCCGCTTTACGCATGAATGAATCCCTTGGTATTACACCAGAGG
ATTTTGCTAATATATCTTCAATATTTTTTGTGTCCTATTTGATTTTTCAAATTCCGAGCAGTATTGGATTGCAAAAGTTA
GGTGCAAGAAAATGGATTAGCGCCATTATTGTTGGTTGGGGAACAGTAACAACGTTAATTTTCTTTGCCAAAGACACCCA
GCATATATTGCTCGCTCGGGTCTTTTTGGGAATATTTGAAGCGGGGTTTTTCCCTGGCATGGTTTACTACCTGGCATGTT
GGTTCCCGGCGCGTGAACGTGGAAAAGTGAATAGCTTTTTTATGTTATCAATCGCAGTTGCATCTGTGCTGGCGGCACCA
ATGTCTGGTTGGATTATTGAACATATGAATACCGGTAACTATGAAGGATGGCGCTGGCTTTTTGCTATTGAAGGCATTCC
TACGGTGTTATTGGGGGCGCTGACCTTTTATTTACTGCCAGATCGTCCGGAAAAAGCCCGCTGGCTTACACCATCGCAAG
TCACCGCATTGGTCGATAAACTTAATTCTGATAACGAAAAAGCCGCAGCATTAAATAAAAATACAAATGCATCTTTTCTG
TCAATCATTAAAAATCCAGTATTACTACAACTCTCATTTGCTTATATGTTTATTCAGGCAGCGGCGTTGGCGGCAAATTA
CTGGTTACCGGGGTTGGTTAAAGGATTTTCATCGGATTTCACAGATACCGATGTCGGTTTGATTATGAGTATTCCGTTTA
TTTTCGCGATGTTCAGTATGCCATTATGGGGATGGCATTCCGATAAAAAGAATGAAAGGAAATGGCATGCCGCACTACCG
ATGTTGGTTGCAGGTTGCGGTTTTTTAATGATCGCACTTGTACCTTCGATGACGCTGCGCATGATGGGATTAACATTATA
CGGTGTAGGCATTCTCAGTTATTACGGTCCGTACTGGGCTTTACCCTCAGCTTTACTTTCACCATCAGGCCTGGCAATCA
GTATTGCGTTTATTAACTCTTGTTCAAGTTTGGGTGGTTTTCTGATCAATAAATCACTTGGCTATGTTTCTACACATTAT
GGAGCCACGGGGATATTTATTGTTGAGGCGATTCTTTGCTTTATCGCCGTAGCTATTTTGTTATCAATGAAAATTGATAA
TAAAAAAGATAACGCCCAGAAAGACAATGTTATTTCACATGCTAAATAA

Upstream 100 bases:

>100_bases
TATCAGATATAACACATCACCTTTTGAACTGGATTATTTTTTACGTAATATCCACTTCGGGCAGTACTCTTATTCATTGA
ACCACAAAAGGTGAAACAAA

Downstream 100 bases:

>100_bases
ATGAGGTTATTTATGAAGATTACATCTGTAGAAATTTTTGACTGCGAACTCAAAAAAAGAGATCAAACTATGGCCTCTTA
TAATCCAGTACTTATTCGGG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MSSPQKDLYEAISIVKRKIIPLAFILYFFNYMDRVNIGFAALRMNESLGITPEDFANISSIFFVSYLIFQIPSSIGLQKL
GARKWISAIIVGWGTVTTLIFFAKDTQHILLARVFLGIFEAGFFPGMVYYLACWFPARERGKVNSFFMLSIAVASVLAAP
MSGWIIEHMNTGNYEGWRWLFAIEGIPTVLLGALTFYLLPDRPEKARWLTPSQVTALVDKLNSDNEKAAALNKNTNASFL
SIIKNPVLLQLSFAYMFIQAAALAANYWLPGLVKGFSSDFTDTDVGLIMSIPFIFAMFSMPLWGWHSDKKNERKWHAALP
MLVAGCGFLMIALVPSMTLRMMGLTLYGVGILSYYGPYWALPSALLSPSGLAISIAFINSCSSLGGFLINKSLGYVSTHY
GATGIFIVEAILCFIAVAILLSMKIDNKKDNAQKDNVISHAK

Sequences:

>Translated_442_residues
MSSPQKDLYEAISIVKRKIIPLAFILYFFNYMDRVNIGFAALRMNESLGITPEDFANISSIFFVSYLIFQIPSSIGLQKL
GARKWISAIIVGWGTVTTLIFFAKDTQHILLARVFLGIFEAGFFPGMVYYLACWFPARERGKVNSFFMLSIAVASVLAAP
MSGWIIEHMNTGNYEGWRWLFAIEGIPTVLLGALTFYLLPDRPEKARWLTPSQVTALVDKLNSDNEKAAALNKNTNASFL
SIIKNPVLLQLSFAYMFIQAAALAANYWLPGLVKGFSSDFTDTDVGLIMSIPFIFAMFSMPLWGWHSDKKNERKWHAALP
MLVAGCGFLMIALVPSMTLRMMGLTLYGVGILSYYGPYWALPSALLSPSGLAISIAFINSCSSLGGFLINKSLGYVSTHY
GATGIFIVEAILCFIAVAILLSMKIDNKKDNAQKDNVISHAK
>Mature_441_residues
SSPQKDLYEAISIVKRKIIPLAFILYFFNYMDRVNIGFAALRMNESLGITPEDFANISSIFFVSYLIFQIPSSIGLQKLG
ARKWISAIIVGWGTVTTLIFFAKDTQHILLARVFLGIFEAGFFPGMVYYLACWFPARERGKVNSFFMLSIAVASVLAAPM
SGWIIEHMNTGNYEGWRWLFAIEGIPTVLLGALTFYLLPDRPEKARWLTPSQVTALVDKLNSDNEKAAALNKNTNASFLS
IIKNPVLLQLSFAYMFIQAAALAANYWLPGLVKGFSSDFTDTDVGLIMSIPFIFAMFSMPLWGWHSDKKNERKWHAALPM
LVAGCGFLMIALVPSMTLRMMGLTLYGVGILSYYGPYWALPSALLSPSGLAISIAFINSCSSLGGFLINKSLGYVSTHYG
ATGIFIVEAILCFIAVAILLSMKIDNKKDNAQKDNVISHAK

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=434, Percent_Identity=30.8755760368664, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI87082320, Length=403, Percent_Identity=22.8287841191067, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI2367379, Length=362, Percent_Identity=24.585635359116, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789152, Length=192, Percent_Identity=30.7291666666667, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789515, Length=307, Percent_Identity=26.3843648208469, Blast_Score=73, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319876, Length=262, Percent_Identity=24.8091603053435, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6319250, Length=181, Percent_Identity=29.2817679558011, Blast_Score=80, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6322025, Length=270, Percent_Identity=24.0740740740741, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322612, Length=212, Percent_Identity=26.4150943396226, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323032, Length=211, Percent_Identity=22.2748815165877, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321502, Length=168, Percent_Identity=26.1904761904762, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48968; Mature: 48837

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPQKDLYEAISIVKRKIIPLAFILYFFNYMDRVNIGFAALRMNESLGITPEDFANISS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHH
IFFVSYLIFQIPSSIGLQKLGARKWISAIIVGWGTVTTLIFFAKDTQHILLARVFLGIFE
HHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AGFFPGMVYYLACWFPARERGKVNSFFMLSIAVASVLAAPMSGWIIEHMNTGNYEGWRWL
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEE
FAIEGIPTVLLGALTFYLLPDRPEKARWLTPSQVTALVDKLNSDNEKAAALNKNTNASFL
EEECCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCCHHHH
SIIKNPVLLQLSFAYMFIQAAALAANYWLPGLVKGFSSDFTDTDVGLIMSIPFIFAMFSM
HHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
PLWGWHSDKKNERKWHAALPMLVAGCGFLMIALVPSMTLRMMGLTLYGVGILSYYGPYWA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LPSALLSPSGLAISIAFINSCSSLGGFLINKSLGYVSTHYGATGIFIVEAILCFIAVAIL
CHHHHCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHH
LSMKIDNKKDNAQKDNVISHAK
HHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSPQKDLYEAISIVKRKIIPLAFILYFFNYMDRVNIGFAALRMNESLGITPEDFANISS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHH
IFFVSYLIFQIPSSIGLQKLGARKWISAIIVGWGTVTTLIFFAKDTQHILLARVFLGIFE
HHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AGFFPGMVYYLACWFPARERGKVNSFFMLSIAVASVLAAPMSGWIIEHMNTGNYEGWRWL
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEE
FAIEGIPTVLLGALTFYLLPDRPEKARWLTPSQVTALVDKLNSDNEKAAALNKNTNASFL
EEECCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCCHHHH
SIIKNPVLLQLSFAYMFIQAAALAANYWLPGLVKGFSSDFTDTDVGLIMSIPFIFAMFSM
HHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
PLWGWHSDKKNERKWHAALPMLVAGCGFLMIALVPSMTLRMMGLTLYGVGILSYYGPYWA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LPSALLSPSGLAISIAFINSCSSLGGFLINKSLGYVSTHYGATGIFIVEAILCFIAVAIL
CHHHHCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHH
LSMKIDNKKDNAQKDNVISHAK
HHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]