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The map label for this gene is yedE

Identifier: 170683280

GI number: 170683280

Start: 1249895

End: 1251100

Strand: Reverse

Name: yedE

Synonym: EcSMS35_1252

Alternate gene names: 170683280

Gene position: 1251100-1249895 (Counterclockwise)

Preceding gene: 170679614

Following gene: 170680412

Centisome position: 24.68

GC content: 55.14

Gene sequence:

>1206_bases
ATGTCATGGCAGCAATTCAAACACGCCTGGTTGATTAAATTCTGGGCGCCCATCCCCGCGGTCATCGCGGCGGGTATTCT
CTCCACTTACTATTTTGGCATTACTGGCACCTTTTGGGCTGTCACGGGTGAATTTACCCGTTGGGGCGGCCAGCTCCTGC
AACTGTTCGGCGTCCATGCTGAAGAGTGGGGTTACTTTAAAATTATCCATCTGGAAGGATCGCCATTAACCCGCATCGAC
GGGATGATGATCCTCGGTATGTTTGGCGGCTGCTTTGCCGCAGCGCTGTGGGCCAACAATGTCAAACTGCGAATGCCGCG
CAGCCGTATCCGCATTATGCAGGCCATCATTGGCGGCATTATCGCCGGTTTTGGCGCGCGTCTGGCAATGGGCTGTAACC
TGGCGGCGTTCTTTACCGGTATTCCTCAGTTCTCGCTGCATGCCTGGTTCTTTGCCATCGCCACTGCCATTGGTTCATGG
TTTGGCGCGCGCTTTACCCTGCTGCCCATCTTCCGTATTCCCGTGAAAATGCAGAAAGTTTCTGCCGCCTCACCGCTGAC
GCAAAAACCGGATCAGGCGCGGCGTCGTTTTCGTCTCGGGATGCTGGTCTTTTTCGGCATGCTGGGCTGGGCGCTGCTCA
CAGCGATGAACCAACCCAAACTGGGGCTGGCAATGCTGTTTGGCGTCGGCTTTGGTTTACTGATTGAACGTGCGCAAATC
TGCTTTACTTCGGCGTTCCGCGATATGTGGATCACCGGACGTACCCATATGGCGAAAGCAATCATTATTGGTATGGCGGT
GAGTGCCATCGGGATCTTCAGTTACGTACAGTTAGGCGTTGAACCCAAAATCATGTGGGCGGGACCAAACGCGGTAATTG
GTGGTTTACTGTTTGGTTTTGGCATCGTGCTGGCTGGCGGCTGCGAAACCGGCTGGATGTACCGCGCGGTAGAAGGCCAG
GTGCACTACTGGTGGGTCGGTCTGGGCAATGTGATCGGCTCAACGATTCTGGCGTATTACTGGGATGATTTCGCTCCGGC
GCTGGCCACCGACTGGGACAAAATCAACCTGCTGAAAACCTTTGGTCCGATGGGGGGCCTGCTGGTGACATATTTGCTGT
TGTTTGCTGCGCTGATGTTGATTATCGGCTGGGAAAAACGCTTCTTCCGCCGTGCGGCACCGCAGACTGCTAAGGAGATC
GCATGA

Upstream 100 bases:

>100_bases
CTAACTATTATTTTTGTGAATTATTACCCCGAAAATAAATTTGCATGGTGTATGATTCGCGACTCTTGTTTCAAACCTTC
TGAGTTCAGAGGCTACATTC

Downstream 100 bases:

>100_bases
AAAATATCGTTCCTGATTACCGCCTTGATATGGTGGGTGAACCCTGCCCTTATCCGGCAGTCGCAACCCTTGAGGCGATG
CCGCAGTTAAAAAAAGGGGA

Product: putative inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MSWQQFKHAWLIKFWAPIPAVIAAGILSTYYFGITGTFWAVTGEFTRWGGQLLQLFGVHAEEWGYFKIIHLEGSPLTRID
GMMILGMFGGCFAAALWANNVKLRMPRSRIRIMQAIIGGIIAGFGARLAMGCNLAAFFTGIPQFSLHAWFFAIATAIGSW
FGARFTLLPIFRIPVKMQKVSAASPLTQKPDQARRRFRLGMLVFFGMLGWALLTAMNQPKLGLAMLFGVGFGLLIERAQI
CFTSAFRDMWITGRTHMAKAIIIGMAVSAIGIFSYVQLGVEPKIMWAGPNAVIGGLLFGFGIVLAGGCETGWMYRAVEGQ
VHYWWVGLGNVIGSTILAYYWDDFAPALATDWDKINLLKTFGPMGGLLVTYLLLFAALMLIIGWEKRFFRRAAPQTAKEI
A

Sequences:

>Translated_401_residues
MSWQQFKHAWLIKFWAPIPAVIAAGILSTYYFGITGTFWAVTGEFTRWGGQLLQLFGVHAEEWGYFKIIHLEGSPLTRID
GMMILGMFGGCFAAALWANNVKLRMPRSRIRIMQAIIGGIIAGFGARLAMGCNLAAFFTGIPQFSLHAWFFAIATAIGSW
FGARFTLLPIFRIPVKMQKVSAASPLTQKPDQARRRFRLGMLVFFGMLGWALLTAMNQPKLGLAMLFGVGFGLLIERAQI
CFTSAFRDMWITGRTHMAKAIIIGMAVSAIGIFSYVQLGVEPKIMWAGPNAVIGGLLFGFGIVLAGGCETGWMYRAVEGQ
VHYWWVGLGNVIGSTILAYYWDDFAPALATDWDKINLLKTFGPMGGLLVTYLLLFAALMLIIGWEKRFFRRAAPQTAKEI
A
>Mature_400_residues
SWQQFKHAWLIKFWAPIPAVIAAGILSTYYFGITGTFWAVTGEFTRWGGQLLQLFGVHAEEWGYFKIIHLEGSPLTRIDG
MMILGMFGGCFAAALWANNVKLRMPRSRIRIMQAIIGGIIAGFGARLAMGCNLAAFFTGIPQFSLHAWFFAIATAIGSWF
GARFTLLPIFRIPVKMQKVSAASPLTQKPDQARRRFRLGMLVFFGMLGWALLTAMNQPKLGLAMLFGVGFGLLIERAQIC
FTSAFRDMWITGRTHMAKAIIIGMAVSAIGIFSYVQLGVEPKIMWAGPNAVIGGLLFGFGIVLAGGCETGWMYRAVEGQV
HYWWVGLGNVIGSTILAYYWDDFAPALATDWDKINLLKTFGPMGGLLVTYLLLFAALMLIIGWEKRFFRRAAPQTAKEIA

Specific function: Unknown

COG id: COG2391

COG function: function code R; Predicted transporter component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0394 family

Homologues:

Organism=Escherichia coli, GI1788238, Length=401, Percent_Identity=100, Blast_Score=800, Evalue=0.0,
Organism=Escherichia coli, GI1788323, Length=102, Percent_Identity=41.1764705882353, Blast_Score=79, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YEDE_ECOLI (P31064)

Other databases:

- EMBL:   L13279
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   F64956
- RefSeq:   AP_002544.1
- RefSeq:   NP_416439.1
- ProteinModelPortal:   P31064
- DIP:   DIP-11839N
- IntAct:   P31064
- MINT:   MINT-1246874
- STRING:   P31064
- EnsemblBacteria:   EBESCT00000003836
- EnsemblBacteria:   EBESCT00000015118
- GeneID:   945192
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW1914
- KEGG:   eco:b1929
- EchoBASE:   EB1612
- EcoGene:   EG11660
- eggNOG:   COG2391
- GeneTree:   EBGT00050000009444
- HOGENOM:   HBG296755
- OMA:   VMIIGMF
- ProtClustDB:   PRK11099
- BioCyc:   EcoCyc:EG11660-MONOMER
- Genevestigator:   P31064
- InterPro:   IPR007272

Pfam domain/function: PF04143 DUF395

EC number: NA

Molecular weight: Translated: 44430; Mature: 44298

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x187bf3e4)-; HASH(0x18cb7544)-; HASH(0x18beace4)-; HASH(0x18830380)-; HASH(0x181893d8)-; HASH(0x18c9be00)-; HASH(0x173258a4)-; HASH(0x18394a00)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWQQFKHAWLIKFWAPIPAVIAAGILSTYYFGITGTFWAVTGEFTRWGGQLLQLFGVHA
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHCCCC
EEWGYFKIIHLEGSPLTRIDGMMILGMFGGCFAAALWANNVKLRMPRSRIRIMQAIIGGI
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHH
IAGFGARLAMGCNLAAFFTGIPQFSLHAWFFAIATAIGSWFGARFTLLPIFRIPVKMQKV
HHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHH
SAASPLTQKPDQARRRFRLGMLVFFGMLGWALLTAMNQPKLGLAMLFGVGFGLLIERAQI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
CFTSAFRDMWITGRTHMAKAIIIGMAVSAIGIFSYVQLGVEPKIMWAGPNAVIGGLLFGF
HHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHH
GIVLAGGCETGWMYRAVEGQVHYWWVGLGNVIGSTILAYYWDDFAPALATDWDKINLLKT
HHHEECCCCCCCEEEEECCCEEEEEEEHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHH
FGPMGGLLVTYLLLFAALMLIIGWEKRFFRRAAPQTAKEIA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCH
>Mature Secondary Structure 
SWQQFKHAWLIKFWAPIPAVIAAGILSTYYFGITGTFWAVTGEFTRWGGQLLQLFGVHA
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHCCCC
EEWGYFKIIHLEGSPLTRIDGMMILGMFGGCFAAALWANNVKLRMPRSRIRIMQAIIGGI
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHH
IAGFGARLAMGCNLAAFFTGIPQFSLHAWFFAIATAIGSWFGARFTLLPIFRIPVKMQKV
HHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHH
SAASPLTQKPDQARRRFRLGMLVFFGMLGWALLTAMNQPKLGLAMLFGVGFGLLIERAQI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
CFTSAFRDMWITGRTHMAKAIIIGMAVSAIGIFSYVQLGVEPKIMWAGPNAVIGGLLFGF
HHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHH
GIVLAGGCETGWMYRAVEGQVHYWWVGLGNVIGSTILAYYWDDFAPALATDWDKINLLKT
HHHEECCCCCCCEEEEECCCEEEEEEEHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHH
FGPMGGLLVTYLLLFAALMLIIGWEKRFFRRAAPQTAKEIA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8371104; 9097040; 9278503