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The map label for this gene is ybhA [H]

Identifier: 170682522

GI number: 170682522

Start: 789624

End: 790442

Strand: Reverse

Name: ybhA [H]

Synonym: EcSMS35_0789

Alternate gene names: 170682522

Gene position: 790442-789624 (Counterclockwise)

Preceding gene: 170680416

Following gene: 170680486

Centisome position: 15.6

GC content: 52.01

Gene sequence:

>819_bases
ATGACCACACGCGTGATTGCTCTCGACTTAGACGGCACCTTATTGACCCCGAAAAAGACCCTGCTTCCTTCATCGATAGA
AGCCCTGGCCCGTGCTCGCGAAGCAGGCTATCGATTAATCATCGTCACAGGTCGCCATCACGTCGCTATTCATCCTTTTT
ATCAGGCGCTGGCGCTGGATACACCTGCTATTTGCTGTAATGGCACCTATTTGTATGATTATCATGCAAAAACCGTGCTG
GAAGCGGACCCAATGCCCGTTAATAAAGCCCTGCAACTCATTGAGATGCTGAATGAACACCACATTCACGGTCTGATGTA
TGTCGATGATGCAATGGTCTATGAGCACCCGACCGGGCATGTCATTCGCACGTCTAACTGGGCGCAAACCCTGCCGCCGG
AACAGCGTCCGACTTTCACACAAGTCGCTTCTCTGGCTGAAACGGCGCAACAAGTTAACGCCGTATGGAAGTTCGCCCTG
ACGCACGACGACCTGCCGCAATTGCAGCATTTTGGTAAGCATGTCGAACATGAACTGGGACTGGAGTGTGAATGGTCCTG
GCACGATCAGGTTGATATTGCACGCGGCGGCAACAGCAAAGGTAAACGTTTGACGAAATGGGTTGAGGCGCAAGGCTGGT
CGATGGAAAACGTCGTGGCGTTCGGCGATAACTTCAATGATATTAGTATGCTGGAAGCCGCTGGTACAGGCGTGGCGATG
GGCAACGCCGATGACGCAGTAAAAGCGCGCGCCAACATTGTGATTGGTGAGAACACCACCGACAGCATTGCCCAGTTCAT
TTATAGCCACCTGATTTAA

Upstream 100 bases:

>100_bases
GGCGGTGAATGCTGAATTAAAACGCAGAATTTTGTCCGATAGTGGTATCGGTGTACCATTCGCGCAGACGAAAATTCTTA
ACCTTAATCTGGAATACGCC

Downstream 100 bases:

>100_bases
TCAGGCGGTTATCGACACACTTTTAATTTGCGCGTACAGCCACAGGCCTGGTTTGATCGCCAGTTCATCCCTGGCCCACG
GGCTGATACGCGCCCACAGC

Product: phosphotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYRLIIVTGRHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVL
EADPMPVNKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFAL
THDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDNFNDISMLEAAGTGVAM
GNADDAVKARANIVIGENTTDSIAQFIYSHLI

Sequences:

>Translated_272_residues
MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYRLIIVTGRHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVL
EADPMPVNKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFAL
THDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDNFNDISMLEAAGTGVAM
GNADDAVKARANIVIGENTTDSIAQFIYSHLI
>Mature_271_residues
TTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYRLIIVTGRHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLE
ADPMPVNKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFALT
HDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDNFNDISMLEAAGTGVAMG
NADDAVKARANIVIGENTTDSIAQFIYSHLI

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates pyridoxalphosphate and erythrose 4-phosphate [H]

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

Organism=Escherichia coli, GI1786982, Length=272, Percent_Identity=98.8970588235294, Blast_Score=561, Evalue=1e-161,
Organism=Escherichia coli, GI48994981, Length=273, Percent_Identity=27.4725274725275, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001757
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR000150
- InterPro:   IPR006380 [H]

Pfam domain/function: PF00702 Hydrolase; PF05116 S6PP [H]

EC number: NA

Molecular weight: Translated: 30245; Mature: 30113

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS01228 COF_1 ; PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYRLIIVTGRHHVAIHPFYQALALD
CCEEEEEEECCCEEECCHHHHCHHHHHHHHHHHHCCCEEEEEECCCEEEECHHHHHHHCC
TPAICCNGTYLYDYHAKTVLEADPMPVNKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGH
CCCEEECCCEEEEECCCEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCEEEEECCCCC
VIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFALTHDDLPQLQHFGKHVEHELG
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHCC
LECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDNFNDISMLEAAGTGVAM
CEEEECCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHCCCCEEE
GNADDAVKARANIVIGENTTDSIAQFIYSHLI
CCCCHHHHEEEEEEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYRLIIVTGRHHVAIHPFYQALALD
CEEEEEEECCCEEECCHHHHCHHHHHHHHHHHHCCCEEEEEECCCEEEECHHHHHHHCC
TPAICCNGTYLYDYHAKTVLEADPMPVNKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGH
CCCEEECCCEEEEECCCEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCEEEEECCCCC
VIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFALTHDDLPQLQHFGKHVEHELG
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHCC
LECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDNFNDISMLEAAGTGVAM
CEEEECCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHCCCCEEE
GNADDAVKARANIVIGENTTDSIAQFIYSHLI
CCCCHHHHEEEEEEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7665460; 8564363; 8905232; 9278503 [H]