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The map label for this gene is yqfA [H]

Identifier: 170682502

GI number: 170682502

Start: 3121170

End: 3121829

Strand: Reverse

Name: yqfA [H]

Synonym: EcSMS35_3032

Alternate gene names: 170682502

Gene position: 3121829-3121170 (Counterclockwise)

Preceding gene: 170683063

Following gene: 170679885

Centisome position: 61.59

GC content: 52.58

Gene sequence:

>660_bases
ATGGTTCAGAAGCCCCTCATTAAGCAGGGATATTCGCTGGCAGAGGAAATTGCCAACAGCGTCAGTCACGGCATTGGGTT
GGTGTTTGGTATCGTTGGGCTGGTGTTGCTACTGGTTCAGGCGGTGGATCTCAATGCCAGCGCCACAGCGATAACCAGTT
ACAGCCTCTATGGCGGCAGTATGATCCTGCTGTTCCTCGCTTCGACGCTCTATCACGCCATTCCCCATCAACGGGCAAAA
ATGTGGCTGAAGAAATTTGACCATTGCGCTATTTACCTGTTGATTGCCGGAACCTACACGCCGTTTTTGCTGGTGGGGCT
GGATTCTCCGTTAGCGCGCGGGTTGATGATTGTTATCTGGAGCCTGGCATTGCTGGGGATTCTGTTCAAACTGACCATCG
CGCACCGATTCAAAATTTTATCTCTGGTGACCTATCTGGCGATGGGCTGGCTGTCGCTGGTGGTGATTTATGAAATGGCA
ATTAAGCTTGCGGCGGGCAGCGTTACCTTACTGGCTGTAGGCGGCGTGGTTTACTCGCTCGGGGTGATTTTCTACGTCTG
CAAACGCATTCCCTACAACCATGCCATCTGGCACGGCTTTGTGCTCGGCGGCAGCGTGTGCCACTTTCTGGCGATCTATT
TATATATTGGGCAGGCGTAA

Upstream 100 bases:

>100_bases
CCAAATCAGAATTTATTTTAGCTAACAGGTGTTCACTGGAACTATTCTCAGTTACGCTGGAGAGGTATACATGTGCGTGT
ACGTTTCTCCGGAGTAAGTT

Downstream 100 bases:

>100_bases
TGGGTGTGCCTTTGTAGGCCTGAAAAGACACACCCGCGTCGCATCAGGCGATAAATGCCTGATGCGACACAGAGATTTAC
TCTTCGAGCGAATACGGCAG

Product: hemolysin III family channel protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MVQKPLIKQGYSLAEEIANSVSHGIGLVFGIVGLVLLLVQAVDLNASATAITSYSLYGGSMILLFLASTLYHAIPHQRAK
MWLKKFDHCAIYLLIAGTYTPFLLVGLDSPLARGLMIVIWSLALLGILFKLTIAHRFKILSLVTYLAMGWLSLVVIYEMA
IKLAAGSVTLLAVGGVVYSLGVIFYVCKRIPYNHAIWHGFVLGGSVCHFLAIYLYIGQA

Sequences:

>Translated_219_residues
MVQKPLIKQGYSLAEEIANSVSHGIGLVFGIVGLVLLLVQAVDLNASATAITSYSLYGGSMILLFLASTLYHAIPHQRAK
MWLKKFDHCAIYLLIAGTYTPFLLVGLDSPLARGLMIVIWSLALLGILFKLTIAHRFKILSLVTYLAMGWLSLVVIYEMA
IKLAAGSVTLLAVGGVVYSLGVIFYVCKRIPYNHAIWHGFVLGGSVCHFLAIYLYIGQA
>Mature_219_residues
MVQKPLIKQGYSLAEEIANSVSHGIGLVFGIVGLVLLLVQAVDLNASATAITSYSLYGGSMILLFLASTLYHAIPHQRAK
MWLKKFDHCAIYLLIAGTYTPFLLVGLDSPLARGLMIVIWSLALLGILFKLTIAHRFKILSLVTYLAMGWLSLVVIYEMA
IKLAAGSVTLLAVGGVVYSLGVIFYVCKRIPYNHAIWHGFVLGGSVCHFLAIYLYIGQA

Specific function: Unknown

COG id: COG1272

COG function: function code R; Predicted membrane protein, hemolysin III homolog

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0073 (Hly-III) family [H]

Homologues:

Organism=Homo sapiens, GI52630445, Length=213, Percent_Identity=31.4553990610329, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI154759275, Length=208, Percent_Identity=30.7692307692308, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI154759277, Length=232, Percent_Identity=27.5862068965517, Blast_Score=82, Evalue=3e-16,
Organism=Escherichia coli, GI1789266, Length=219, Percent_Identity=99.5433789954338, Blast_Score=430, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI71996356, Length=217, Percent_Identity=31.7972350230415, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24640324, Length=234, Percent_Identity=30.7692307692308, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004254
- InterPro:   IPR005744 [H]

Pfam domain/function: PF03006 HlyIII [H]

EC number: NA

Molecular weight: Translated: 23861; Mature: 23861

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQKPLIKQGYSLAEEIANSVSHGIGLVFGIVGLVLLLVQAVDLNASATAITSYSLYGGS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
MILLFLASTLYHAIPHQRAKMWLKKFDHCAIYLLIAGTYTPFLLVGLDSPLARGLMIVIW
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHH
SLALLGILFKLTIAHRFKILSLVTYLAMGWLSLVVIYEMAIKLAAGSVTLLAVGGVVYSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
GVIFYVCKRIPYNHAIWHGFVLGGSVCHFLAIYLYIGQA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVQKPLIKQGYSLAEEIANSVSHGIGLVFGIVGLVLLLVQAVDLNASATAITSYSLYGGS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
MILLFLASTLYHAIPHQRAKMWLKKFDHCAIYLLIAGTYTPFLLVGLDSPLARGLMIVIW
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHH
SLALLGILFKLTIAHRFKILSLVTYLAMGWLSLVVIYEMAIKLAAGSVTLLAVGGVVYSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
GVIFYVCKRIPYNHAIWHGFVLGGSVCHFLAIYLYIGQA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]