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The map label for this gene is entD [H]

Identifier: 170682382

GI number: 170682382

Start: 610570

End: 611190

Strand: Reverse

Name: entD [H]

Synonym: EcSMS35_0601

Alternate gene names: 170682382

Gene position: 611190-610570 (Counterclockwise)

Preceding gene: 170680124

Following gene: 170683850

Centisome position: 12.06

GC content: 48.15

Gene sequence:

>621_bases
ATGAAAACTACGCATACCGCCCTCCCCTTTGCCGGAAATACGCTGCATTTTGTTAAGTTCGATCCGGCGAGTTTTTGTGA
GCAGGATTTACTCTGGCTGCCACACTACGCGCAACTGCAACACGCTGGACGTAAACGTAAAACAGAGCATTTAGCCGGAC
GGATCGCTGCAGTTTATGCGCTGCGGGAATATGGCTATAAATGTGTGCCCGCAATCGGCGAGCTACGCCAACCTGTGTGG
CCTGCGGGGGTATACGGCAGCATTAGTCACTGTGGGACTACGGCATTAGCCGTGGTATCTCGTCAACCGATTGGCATTGA
TATTGAAGAGATTTTTTCTGCGCAAACAGCGGCAGAATTGACAGACAACATTATTACGCCAGCGGAACACAAGCGACTCG
CAGACTGCGGTTTAGCCTTTTCTCTGGCGCTGACACTGGCATTTTCCGCCAAAGAGAGCGCATTTAAGGCATGTGAGAGA
CAAACTGATGCAGGATTTCTGGACTATCAGATAATTAACTGGAATAAACAGCAGGTCATCATTCATCGTGAGAATAAGAT
GTTTGCTGTGCACTGGCAGATAAAAGAAAAGATAGTCATAACGCTGTGCCAACACAATTAA

Upstream 100 bases:

>100_bases
AAAATCTTGCCAATTCAATATATTGCAGGATAGTGTAGGCCTGATAAGCGTAGCGCATCAGGCAGTTTTGCGTTTGTCAT
CAGTCTCTAATATGGTCGAC

Downstream 100 bases:

>100_bases
TTGACAATATCTGGTACGATTCGCCCGCAGCCATCACTGACCACGGGCGAAAGTGTAAAGCAGGTGCCTTACCATCCTGA
CCTGACAACCGGATATGCGG

Product: phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex

Products: NA

Alternate protein names: Enterobactin synthase component D; Enterochelin synthase D [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MKTTHTALPFAGNTLHFVKFDPASFCEQDLLWLPHYAQLQHAGRKRKTEHLAGRIAAVYALREYGYKCVPAIGELRQPVW
PAGVYGSISHCGTTALAVVSRQPIGIDIEEIFSAQTAAELTDNIITPAEHKRLADCGLAFSLALTLAFSAKESAFKACER
QTDAGFLDYQIINWNKQQVIIHRENKMFAVHWQIKEKIVITLCQHN

Sequences:

>Translated_206_residues
MKTTHTALPFAGNTLHFVKFDPASFCEQDLLWLPHYAQLQHAGRKRKTEHLAGRIAAVYALREYGYKCVPAIGELRQPVW
PAGVYGSISHCGTTALAVVSRQPIGIDIEEIFSAQTAAELTDNIITPAEHKRLADCGLAFSLALTLAFSAKESAFKACER
QTDAGFLDYQIINWNKQQVIIHRENKMFAVHWQIKEKIVITLCQHN
>Mature_206_residues
MKTTHTALPFAGNTLHFVKFDPASFCEQDLLWLPHYAQLQHAGRKRKTEHLAGRIAAVYALREYGYKCVPAIGELRQPVW
PAGVYGSISHCGTTALAVVSRQPIGIDIEEIFSAQTAAELTDNIITPAEHKRLADCGLAFSLALTLAFSAKESAFKACER
QTDAGFLDYQIINWNKQQVIIHRENKMFAVHWQIKEKIVITLCQHN

Specific function: Catalyzes the transfer of the 4'-phosphopantetheine moiety from coenzyme A to apo-domains of both entB (an ArCP domain) and entF (a PCP domain). Plays an essential role in the assembly of the enterobactin [H]

COG id: COG2977

COG function: function code Q; Phosphopantetheinyl transferase component of siderophore synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. EntD family [H]

Homologues:

Organism=Escherichia coli, GI1786797, Length=206, Percent_Identity=93.6893203883495, Blast_Score=405, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278
- InterPro:   IPR003542 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: 2.7.8.-

Molecular weight: Translated: 23090; Mature: 23090

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTHTALPFAGNTLHFVKFDPASFCEQDLLWLPHYAQLQHAGRKRKTEHLAGRIAAVYA
CCCCCCCCCCCCCEEEEEEECHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LREYGYKCVPAIGELRQPVWPAGVYGSISHCGTTALAVVSRQPIGIDIEEIFSAQTAAEL
HHHCCCEECCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
TDNIITPAEHKRLADCGLAFSLALTLAFSAKESAFKACERQTDAGFLDYQIINWNKQQVI
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEE
IHRENKMFAVHWQIKEKIVITLCQHN
EEECCCEEEEEEEECCEEEEEEECCC
>Mature Secondary Structure
MKTTHTALPFAGNTLHFVKFDPASFCEQDLLWLPHYAQLQHAGRKRKTEHLAGRIAAVYA
CCCCCCCCCCCCCEEEEEEECHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LREYGYKCVPAIGELRQPVWPAGVYGSISHCGTTALAVVSRQPIGIDIEEIFSAQTAAEL
HHHCCCEECCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
TDNIITPAEHKRLADCGLAFSLALTLAFSAKESAFKACERQTDAGFLDYQIINWNKQQVI
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEE
IHRENKMFAVHWQIKEKIVITLCQHN
EEECCCEEEEEEEECCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]