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The map label for this gene is glgP [H]

Identifier: 170682143

GI number: 170682143

Start: 3774520

End: 3776967

Strand: Reverse

Name: glgP [H]

Synonym: EcSMS35_3710

Alternate gene names: 170682143

Gene position: 3776967-3774520 (Counterclockwise)

Preceding gene: 170680998

Following gene: 170681684

Centisome position: 74.52

GC content: 51.55

Gene sequence:

>2448_bases
ATGAATGCTCCGTTTACATATTCATCGCCCACGCTTAGCGTAGAAGCTCTTAAGCATTCTATCGCTTACAAGCTGATGTT
TACGATTGGCAAGGACCCGGTCGTCGCCAATAAACATGAATGGCTGAACGCAACATTATTTGCTGTGCGCGATCGTCTCG
TGGAGCGCTGGTTACGTTCAAACCGTGCCCAGTTGTCGCAAGAAACTCGTCAGGTTTACTACCTGTCGATGGAGTTTTTG
ATTGGCCGTACGCTCTCCAACGCCATGTTGTCGCTAGGAATTTACGAAGATGTACAGGGCGCACTGGAAGCGATGGGGTT
AAATCTCGAAGAGCTGATTGATGAAGAAAATGACCCGGGCCTCGGTAACGGTGGCCTGGGACGTCTGGCGGCTTGCTTCC
TCGATTCTCTGGCGACGTTAGGGTTGCCGGGGCGCGGTTACGGCATCCGCTATGACTACGGTATGTTCAAGCAGAACATC
GTTAACGGTAGCCAGAAAGAGTCGCCTGACTACTGGCTGGAATACGGTAACCCGTGGGAATTCAAACGCCACAACACGCG
CTATAAAGTCCGTTTTGGCGGTCGCATTCAGCAGGAAGGTAAAAAAACGCGCTGGATTGAAACCGAAGAGATTCTGGGAG
TAGCTTACGATCAGATAATCCCAGGTTACGACACCGACGCGACCAACACGTTGCGTTTGTGGAGTGCCCAAGCCAGTAGC
GAAATTAACCTCGGTAAATTCAACCAGGGCGACTACTTCGCGGCAGTGGAAGATAAAAACCACTCCGAGAACGTATCTCG
CGTACTGTATCCGGACGACTCCACCTACTCCGGGCGTGAGCTGCGACTGCGTCAGGAATACTTCCTGGTTTCCTCGACCA
TTCAGGACATTTTAAGCCGCCATTATCAGTTGCATAAAACCTACGATAACCTGGCGGATAAAATTGCGATTCACCTCAAC
GATACCCATCCGGTGCTGTCGATTCCTGAGATGATGCGTCTGCTGATCGATGAGCACCAATTTAGCTGGGACGACGCGTT
TGAAGTGTGTTGTCAGGTCTTCTCCTACACCAACCACACGCTAATGAGCGAGGCGCTGGAAACCTGGCCAGTCGATATGC
TGGGTAAAATTCTGCCGCGTCACCTGCAGATCATCTTTGAAATCAACGACTATTTCCTGAAAACTTTGCAGGAACAGTAT
CCGAACGATACCGATCTGCTGGGACGGGCGTCGATCATCGATGAATCCAACGGTCGTCGTGTGCGTATGGCCTGGCTGGC
GGTTGTGGTGAGCCACAAAGTTAACGGTGTATCGGAGCTGCACTCTAACCTGATGGTGCAATCGCTATTTGCCGACTTTG
CGAAAATCTTCCCGGGTCGTTTCACCAACGTCACCAACGGTGTGACGCCGCGTCGCTGGCTGGCGGTAGCGAACCCATCG
CTTTCAGCTGTGTTGGACGAACACCTGGGCCGCAACTGGCGCACCGACCTTAGTCTGCTTAATGAGCTGCAACAACACTG
TGATTTCCCAATGGTTAATCACGCGGTGCATCAGGCGAAGCTGGAGAACAAAAAGCGTCTGGCGGAGTATATCGCCCAGC
AGCTGAATGTGGTGGTAAATCCGAAAGCGCTGTTCGATGTGCAAATCAAACGTATTCACGAATACAAACGTCAATTGATG
AATGTGTTGCACGTGATCACCCGCTATAACCGCATCAAGGCCGACCCGGATGCGAAGTGGGTACCGCGCGTGAATATTTT
TGGCGGTAAGGCGGCTTCGGCCTATTACATGGCGAAGCACATTATTCATTTGATCAATGACGTAGCGAAAGTGATCAACA
ACGATCCGCAGATTGGCGACAAGCTGAAAGTCGTGTTCATCCCGAACTACAGTGTTAGCCTGGCGCAGTTGATCATTCCG
GCGGCCGATCTATCTGAACAGATTTCGCTGGCGGGGACGGAAGCTTCCGGCACCAGTAACATGAAGTTTGCGCTTAACGG
CGCGCTGACTATCGGTACGCTGGACGGTGCGAATGTCGAGATGCTGGATCATGTCGGTGCTGACAATATCTTTATCTTTG
GTAACACAGCGGAAGAAGTGGAAGAACTGCGTCGTCAGGGCTACAAACCGCGTGAATACTACGAGAAAGATGAGGAGCTG
CATCAGGTGCTGACGCAAATCGGCAGCGGTGTATTCAGTCCGGAAGATCCGGGTCGCTATCGCGATCTGGTCGATTCGCT
GATCAACTTCGGCGATCACTACCAGGTACTGGCGGATTATCGCAGCTATGTCGATTGTCAGGATAAAGTCGACGAACTCT
ACGAGCGTCAGGAAGAGTGGACCGCAAAAGCGATGCTGAACATTGCCAATATGGGCTACTTCTCTTCTGACCGTACGATC
AAAGAGTACGCCGATCATATCTGGCATATTGATCCGGTGAGATTGTAA

Upstream 100 bases:

>100_bases
GCAACGTCAGGCTATGGCAATGGATTTTAGCTGGCAGGTCGCGGCGAAGTCGTACCGTGAGCTTTACTATCGCTTGAAAT
AGTTTTCAGGAAACGCCTAT

Downstream 100 bases:

>100_bases
GTTCGCTAAAAAACAGAACGGGGCCAAAAGGTCCCGTTTTTTTTCGCCTTTATTTAGGAAAAGTGTCCAGAGGGGGCGAG
GGTTATCGGGGAGTATAATT

Product: glycogen phosphorylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 815; Mature: 815

Protein sequence:

>815_residues
MNAPFTYSSPTLSVEALKHSIAYKLMFTIGKDPVVANKHEWLNATLFAVRDRLVERWLRSNRAQLSQETRQVYYLSMEFL
IGRTLSNAMLSLGIYEDVQGALEAMGLNLEELIDEENDPGLGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNI
VNGSQKESPDYWLEYGNPWEFKRHNTRYKVRFGGRIQQEGKKTRWIETEEILGVAYDQIIPGYDTDATNTLRLWSAQASS
EINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTYSGRELRLRQEYFLVSSTIQDILSRHYQLHKTYDNLADKIAIHLN
DTHPVLSIPEMMRLLIDEHQFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGKILPRHLQIIFEINDYFLKTLQEQY
PNDTDLLGRASIIDESNGRRVRMAWLAVVVSHKVNGVSELHSNLMVQSLFADFAKIFPGRFTNVTNGVTPRRWLAVANPS
LSAVLDEHLGRNWRTDLSLLNELQQHCDFPMVNHAVHQAKLENKKRLAEYIAQQLNVVVNPKALFDVQIKRIHEYKRQLM
NVLHVITRYNRIKADPDAKWVPRVNIFGGKAASAYYMAKHIIHLINDVAKVINNDPQIGDKLKVVFIPNYSVSLAQLIIP
AADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEMLDHVGADNIFIFGNTAEEVEELRRQGYKPREYYEKDEEL
HQVLTQIGSGVFSPEDPGRYRDLVDSLINFGDHYQVLADYRSYVDCQDKVDELYERQEEWTAKAMLNIANMGYFSSDRTI
KEYADHIWHIDPVRL

Sequences:

>Translated_815_residues
MNAPFTYSSPTLSVEALKHSIAYKLMFTIGKDPVVANKHEWLNATLFAVRDRLVERWLRSNRAQLSQETRQVYYLSMEFL
IGRTLSNAMLSLGIYEDVQGALEAMGLNLEELIDEENDPGLGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNI
VNGSQKESPDYWLEYGNPWEFKRHNTRYKVRFGGRIQQEGKKTRWIETEEILGVAYDQIIPGYDTDATNTLRLWSAQASS
EINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTYSGRELRLRQEYFLVSSTIQDILSRHYQLHKTYDNLADKIAIHLN
DTHPVLSIPEMMRLLIDEHQFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGKILPRHLQIIFEINDYFLKTLQEQY
PNDTDLLGRASIIDESNGRRVRMAWLAVVVSHKVNGVSELHSNLMVQSLFADFAKIFPGRFTNVTNGVTPRRWLAVANPS
LSAVLDEHLGRNWRTDLSLLNELQQHCDFPMVNHAVHQAKLENKKRLAEYIAQQLNVVVNPKALFDVQIKRIHEYKRQLM
NVLHVITRYNRIKADPDAKWVPRVNIFGGKAASAYYMAKHIIHLINDVAKVINNDPQIGDKLKVVFIPNYSVSLAQLIIP
AADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEMLDHVGADNIFIFGNTAEEVEELRRQGYKPREYYEKDEEL
HQVLTQIGSGVFSPEDPGRYRDLVDSLINFGDHYQVLADYRSYVDCQDKVDELYERQEEWTAKAMLNIANMGYFSSDRTI
KEYADHIWHIDPVRL
>Mature_815_residues
MNAPFTYSSPTLSVEALKHSIAYKLMFTIGKDPVVANKHEWLNATLFAVRDRLVERWLRSNRAQLSQETRQVYYLSMEFL
IGRTLSNAMLSLGIYEDVQGALEAMGLNLEELIDEENDPGLGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNI
VNGSQKESPDYWLEYGNPWEFKRHNTRYKVRFGGRIQQEGKKTRWIETEEILGVAYDQIIPGYDTDATNTLRLWSAQASS
EINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTYSGRELRLRQEYFLVSSTIQDILSRHYQLHKTYDNLADKIAIHLN
DTHPVLSIPEMMRLLIDEHQFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGKILPRHLQIIFEINDYFLKTLQEQY
PNDTDLLGRASIIDESNGRRVRMAWLAVVVSHKVNGVSELHSNLMVQSLFADFAKIFPGRFTNVTNGVTPRRWLAVANPS
LSAVLDEHLGRNWRTDLSLLNELQQHCDFPMVNHAVHQAKLENKKRLAEYIAQQLNVVVNPKALFDVQIKRIHEYKRQLM
NVLHVITRYNRIKADPDAKWVPRVNIFGGKAASAYYMAKHIIHLINDVAKVINNDPQIGDKLKVVFIPNYSVSLAQLIIP
AADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEMLDHVGADNIFIFGNTAEEVEELRRQGYKPREYYEKDEEL
HQVLTQIGSGVFSPEDPGRYRDLVDSLINFGDHYQVLADYRSYVDCQDKVDELYERQEEWTAKAMLNIANMGYFSSDRTI
KEYADHIWHIDPVRL

Specific function: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties [

COG id: COG0058

COG function: function code G; Glucan phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycogen phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI71037379, Length=812, Percent_Identity=50, Blast_Score=801, Evalue=0.0,
Organism=Homo sapiens, GI21361370, Length=810, Percent_Identity=50.1234567901235, Blast_Score=800, Evalue=0.0,
Organism=Homo sapiens, GI5032009, Length=810, Percent_Identity=49.0123456790123, Blast_Score=797, Evalue=0.0,
Organism=Homo sapiens, GI255653002, Length=812, Percent_Identity=48.5221674876847, Blast_Score=756, Evalue=0.0,
Organism=Homo sapiens, GI257900462, Length=665, Percent_Identity=49.0225563909774, Blast_Score=692, Evalue=0.0,
Organism=Escherichia coli, GI2367228, Length=815, Percent_Identity=99.8773006134969, Blast_Score=1694, Evalue=0.0,
Organism=Escherichia coli, GI48994936, Length=766, Percent_Identity=47.7806788511749, Blast_Score=733, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17564550, Length=810, Percent_Identity=50.2469135802469, Blast_Score=829, Evalue=0.0,
Organism=Caenorhabditis elegans, GI32566204, Length=810, Percent_Identity=50.2469135802469, Blast_Score=828, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325418, Length=811, Percent_Identity=47.2256473489519, Blast_Score=727, Evalue=0.0,
Organism=Drosophila melanogaster, GI78706832, Length=809, Percent_Identity=49.4437577255871, Blast_Score=816, Evalue=0.0,
Organism=Drosophila melanogaster, GI24581010, Length=809, Percent_Identity=49.4437577255871, Blast_Score=816, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011833
- InterPro:   IPR000811 [H]

Pfam domain/function: PF00343 Phosphorylase [H]

EC number: =2.4.1.1 [H]

Molecular weight: Translated: 93217; Mature: 93217

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00102 PHOSPHORYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPFTYSSPTLSVEALKHSIAYKLMFTIGKDPVVANKHEWLNATLFAVRDRLVERWLRS
CCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NRAQLSQETRQVYYLSMEFLIGRTLSNAMLSLGIYEDVQGALEAMGLNLEELIDEENDPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHCCCCCCC
LGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNIVNGSQKESPDYWLEYGNPWE
CCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHCCCCCCCCCCCEEECCCCCC
FKRHNTRYKVRFGGRIQQEGKKTRWIETEEILGVAYDQIIPGYDTDATNTLRLWSAQASS
CCCCCCEEEEEECCEEHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCC
EINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTYSGRELRLRQEYFLVSSTIQDILSR
CCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHH
HYQLHKTYDNLADKIAIHLNDTHPVLSIPEMMRLLIDEHQFSWDDAFEVCCQVFSYTNHT
HHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHH
LMSEALETWPVDMLGKILPRHLQIIFEINDYFLKTLQEQYPNDTDLLGRASIIDESNGRR
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHEECCCCCE
VRMAWLAVVVSHKVNGVSELHSNLMVQSLFADFAKIFPGRFTNVTNGVTPRRWLAVANPS
EHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHEEEECCCC
LSAVLDEHLGRNWRTDLSLLNELQQHCDFPMVNHAVHQAKLENKKRLAEYIAQQLNVVVN
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEC
PKALFDVQIKRIHEYKRQLMNVLHVITRYNRIKADPDAKWVPRVNIFGGKAASAYYMAKH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHH
IIHLINDVAKVINNDPQIGDKLKVVFIPNYSVSLAQLIIPAADLSEQISLAGTEASGTSN
HHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHCHHHHHHHHHCCCCCCCCCCC
MKFALNGALTIGTLDGANVEMLDHVGADNIFIFGNTAEEVEELRRQGYKPREYYEKDEEL
EEEEEECEEEEEECCCCCHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCCHHHHCCHHHH
HQVLTQIGSGVFSPEDPGRYRDLVDSLINFGDHYQVLADYRSYVDCQDKVDELYERQEEW
HHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
TAKAMLNIANMGYFSSDRTIKEYADHIWHIDPVRL
HHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNAPFTYSSPTLSVEALKHSIAYKLMFTIGKDPVVANKHEWLNATLFAVRDRLVERWLRS
CCCCCCCCCCCCCHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NRAQLSQETRQVYYLSMEFLIGRTLSNAMLSLGIYEDVQGALEAMGLNLEELIDEENDPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHCCCCCCC
LGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNIVNGSQKESPDYWLEYGNPWE
CCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHCCCCCCCCCCCEEECCCCCC
FKRHNTRYKVRFGGRIQQEGKKTRWIETEEILGVAYDQIIPGYDTDATNTLRLWSAQASS
CCCCCCEEEEEECCEEHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCC
EINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTYSGRELRLRQEYFLVSSTIQDILSR
CCCCCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHH
HYQLHKTYDNLADKIAIHLNDTHPVLSIPEMMRLLIDEHQFSWDDAFEVCCQVFSYTNHT
HHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHH
LMSEALETWPVDMLGKILPRHLQIIFEINDYFLKTLQEQYPNDTDLLGRASIIDESNGRR
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHEECCCCCE
VRMAWLAVVVSHKVNGVSELHSNLMVQSLFADFAKIFPGRFTNVTNGVTPRRWLAVANPS
EHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHEEEECCCC
LSAVLDEHLGRNWRTDLSLLNELQQHCDFPMVNHAVHQAKLENKKRLAEYIAQQLNVVVN
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEC
PKALFDVQIKRIHEYKRQLMNVLHVITRYNRIKADPDAKWVPRVNIFGGKAASAYYMAKH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHH
IIHLINDVAKVINNDPQIGDKLKVVFIPNYSVSLAQLIIPAADLSEQISLAGTEASGTSN
HHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHCHHHHHHHHHCCCCCCCCCCC
MKFALNGALTIGTLDGANVEMLDHVGADNIFIFGNTAEEVEELRRQGYKPREYYEKDEEL
EEEEEECEEEEEECCCCCHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCCHHHHCCHHHH
HQVLTQIGSGVFSPEDPGRYRDLVDSLINFGDHYQVLADYRSYVDCQDKVDELYERQEEW
HHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
TAKAMLNIANMGYFSSDRTIKEYADHIWHIDPVRL
HHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2645169; 3047129; 9278503; 2975249; 3097003 [H]