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The map label for this gene is rhmA [H]

Identifier: 170681725

GI number: 170681725

Start: 2447422

End: 2448225

Strand: Reverse

Name: rhmA [H]

Synonym: EcSMS35_2399

Alternate gene names: 170681725

Gene position: 2448225-2447422 (Counterclockwise)

Preceding gene: 170682702

Following gene: 170680293

Centisome position: 48.3

GC content: 53.98

Gene sequence:

>804_bases
ATGAACGCATTATTAAGCAATCCCTTTAAAGAACGTTTACGCAAGGGCGAAGTGCAAATTGGTCTGTGGTTAAGCTCGAC
TACTTCTTATATGGCAGAAATTGCCGCCACCTCCGGTTATGACTGGTTGCTGATTGACGGGGAGCACGCGCCAAACACCA
TTCAGGATCTTTATCACCAGCTACAGGCGGTAGCGCCCTATGCCAGCCAACCCGTGATCCGTCCGGTGGAAGCCAGTAAG
TCGCTGATTAAACAAGTCCTGGATATTGGCGCGCAAACTCTACTGATCCCGATGGTCGATACTGCCGATCAGGCACGTCA
GGTGGTGTCTGCCACGCGCTATCCTCCCTACGGTGAGCGTGGTGTTGGGGCCAGTGTGGCACGGGCTGCTCGCTGGGGAC
GCATTGAGAATTACATGGCGCACGTCAACGATTCGCTTTGTCTGTTGGTGCAGGTGGAAAGTAAGACGGCACTGGATAAC
CTGGACGAAATCCTCGGCGTCGAAGGAATTGATGGCGTGTTTATTGGACCTGCGGATCTTTCTGCCTCGTTGGGCTACCC
GGATAACGCCGGGCACCCGGAAGTGCAGCGAATTATTGAAACCAGCATTCGGCGGATCCGTGCTGCGGGTAAAGCTGCTG
GTTTTCTGGCTGTGGCTCCTGATATGGCGCAGCAATGCCTGGCGTGGGGAGCGAACTTTGTCGCTGTTGGCGTTGACACG
ATGCTCTACAGCGATGCCCTGGATCAACGACTGGCGATGTTTAAATCAGGCAAAAATGGGCCACGCGTAAAAGGTAGTTA
TTGA

Upstream 100 bases:

>100_bases
CGGTGGCGGTCATCGGTTCGCTGATTATTTTCACTCTGCGTGTAAATCGCACTGTTGCGCAGACCGACGTGGCACATCAT
TAAATAGGTTAAGGAACACG

Downstream 100 bases:

>100_bases
TATCAAAGGCCCATGGGGATCGGCTGTGGGCCTGTGTTAATTAGTGGTTATTCGCTGCCAGATCGGCTTCGCTTAGCTGA
GTGGCCGCGAGCACCTGGTC

Product: putative aldolase

Products: NA

Alternate protein names: KDR aldolase; 2-dehydro-3-deoxyrhamnonate aldolase [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MNALLSNPFKERLRKGEVQIGLWLSSTTSYMAEIAATSGYDWLLIDGEHAPNTIQDLYHQLQAVAPYASQPVIRPVEASK
SLIKQVLDIGAQTLLIPMVDTADQARQVVSATRYPPYGERGVGASVARAARWGRIENYMAHVNDSLCLLVQVESKTALDN
LDEILGVEGIDGVFIGPADLSASLGYPDNAGHPEVQRIIETSIRRIRAAGKAAGFLAVAPDMAQQCLAWGANFVAVGVDT
MLYSDALDQRLAMFKSGKNGPRVKGSY

Sequences:

>Translated_267_residues
MNALLSNPFKERLRKGEVQIGLWLSSTTSYMAEIAATSGYDWLLIDGEHAPNTIQDLYHQLQAVAPYASQPVIRPVEASK
SLIKQVLDIGAQTLLIPMVDTADQARQVVSATRYPPYGERGVGASVARAARWGRIENYMAHVNDSLCLLVQVESKTALDN
LDEILGVEGIDGVFIGPADLSASLGYPDNAGHPEVQRIIETSIRRIRAAGKAAGFLAVAPDMAQQCLAWGANFVAVGVDT
MLYSDALDQRLAMFKSGKNGPRVKGSY
>Mature_267_residues
MNALLSNPFKERLRKGEVQIGLWLSSTTSYMAEIAATSGYDWLLIDGEHAPNTIQDLYHQLQAVAPYASQPVIRPVEASK
SLIKQVLDIGAQTLLIPMVDTADQARQVVSATRYPPYGERGVGASVARAARWGRIENYMAHVNDSLCLLVQVESKTALDN
LDEILGVEGIDGVFIGPADLSASLGYPDNAGHPEVQRIIETSIRRIRAAGKAAGFLAVAPDMAQQCLAWGANFVAVGVDT
MLYSDALDQRLAMFKSGKNGPRVKGSY

Specific function: Catalyzes the reversible retro-aldol cleavage of 2-keto- 3-deoxy-L-rhamnonate (KDR) to pyruvate and lactaldehyde [H]

COG id: COG3836

COG function: function code G; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family. KDR aldolase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788578, Length=267, Percent_Identity=97.3782771535581, Blast_Score=535, Evalue=1e-153,
Organism=Escherichia coli, GI1789514, Length=254, Percent_Identity=42.9133858267717, Blast_Score=214, Evalue=5e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: NA

Molecular weight: Translated: 28859; Mature: 28859

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALLSNPFKERLRKGEVQIGLWLSSTTSYMAEIAATSGYDWLLIDGEHAPNTIQDLYHQ
CCCCCCCHHHHHHHCCCEEEEEEECHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHH
LQAVAPYASQPVIRPVEASKSLIKQVLDIGAQTLLIPMVDTADQARQVVSATRYPPYGER
HHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCC
GVGASVARAARWGRIENYMAHVNDSLCLLVQVESKTALDNLDEILGVEGIDGVFIGPADL
CCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHCCCCCCCEEECCCCC
SASLGYPDNAGHPEVQRIIETSIRRIRAAGKAAGFLAVAPDMAQQCLAWGANFVAVGVDT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHCCCEEEEHHHH
MLYSDALDQRLAMFKSGKNGPRVKGSY
HHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNALLSNPFKERLRKGEVQIGLWLSSTTSYMAEIAATSGYDWLLIDGEHAPNTIQDLYHQ
CCCCCCCHHHHHHHCCCEEEEEEECHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHH
LQAVAPYASQPVIRPVEASKSLIKQVLDIGAQTLLIPMVDTADQARQVVSATRYPPYGER
HHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCC
GVGASVARAARWGRIENYMAHVNDSLCLLVQVESKTALDNLDEILGVEGIDGVFIGPADL
CCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHCCCCCCCEEECCCCC
SASLGYPDNAGHPEVQRIIETSIRRIRAAGKAAGFLAVAPDMAQQCLAWGANFVAVGVDT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHCCCEEEEHHHH
MLYSDALDQRLAMFKSGKNGPRVKGSY
HHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA