Click here to switch to the map view.

The map label for this gene is mtgA [H]

Identifier: 170681307

GI number: 170681307

Start: 3575694

End: 3576422

Strand: Reverse

Name: mtgA [H]

Synonym: EcSMS35_3503

Alternate gene names: 170681307

Gene position: 3576422-3575694 (Counterclockwise)

Preceding gene: 170683821

Following gene: 170683530

Centisome position: 70.56

GC content: 52.54

Gene sequence:

>729_bases
ATGAGTAAAAGCCGCTTAACGGTGTTTAGTTTCGTTCGCCGTTTTCTTCTGCGGTTAATGGTTGTCCTCGCCGTTTTCTG
GGGCGGGGGCATCGCGTTGTTTAGCGTTGCGCCTGTTCCCTTCTCAGCGGTAATGGTTGAGCGGCAAGTCAGCGCCTGGC
TGCATGGCAATTTTCGTTACGTGGCACATTCTGACTGGGTCAGTATGGATCAAATCTCGCCGTGGATGGGACTGGCGGTG
ATTGCCGCAGAAGATCAGAAATTTCCTGAGCACTGGGGCTTTGATGTCGCTTCCATTGAGCAAGCCCTGGCGCACAACGA
ACGCAATGAAAACCGTATTCGCGGTGCGTCAACGATTTCTCAGCAGACAGCCAAAAATCTCTTTTTATGGGATGGGCGCA
GCTGGGTTCGAAAAGGGCTGGAAGCCGGATTAACGCTGGGGATAGAAACGGTCTGGAGCAAAAAGCGTATCCTGACGGTT
TACCTGAATATCGCCGAATTTGGCGACGGTGTGTTTGGCGTCGAAGCTGCGGCACAACGTTATTTCCACAAACCCGCGAG
CAAGCTTACCCGGTCGGAAGCTGCATTACTGGCAGCTGTATTACCTAATCCACTTCGTTTCAAAGTCTCCGCGCCATCGG
GCTACGTGCGTAGCCGTCAGGCGTGGATTTTACGGCAGATGTATCAGTTAGGCGGTGAGCCGTTTATGCAACAACACCAG
CTTGATTAA

Upstream 100 bases:

>100_bases
ATAAGATTGTCACCACCCCTGCATATATGCTGGCGCAGAACATTGCAGAAGCGGCGAGCGGCATTGATAAGCTGGTTTCC
CGCGTGCTGGTCCTGGCGGA

Downstream 100 bases:

>100_bases
GCTTCGCGCGAAGTGAGGGCCAGCGTTTTGCTCTCACGAGGTTGCAGATCTTTCTGCAGGGCAATAGCCAGCGCCGGTTG
GGCGATAAATCGTTTCCACA

Product: monofunctional biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSKSRLTVFSFVRRFLLRLMVVLAVFWGGGIALFSVAPVPFSAVMVERQVSAWLHGNFRYVAHSDWVSMDQISPWMGLAV
IAAEDQKFPEHWGFDVASIEQALAHNERNENRIRGASTISQQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTV
YLNIAEFGDGVFGVEAAAQRYFHKPASKLTRSEAALLAAVLPNPLRFKVSAPSGYVRSRQAWILRQMYQLGGEPFMQQHQ
LD

Sequences:

>Translated_242_residues
MSKSRLTVFSFVRRFLLRLMVVLAVFWGGGIALFSVAPVPFSAVMVERQVSAWLHGNFRYVAHSDWVSMDQISPWMGLAV
IAAEDQKFPEHWGFDVASIEQALAHNERNENRIRGASTISQQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTV
YLNIAEFGDGVFGVEAAAQRYFHKPASKLTRSEAALLAAVLPNPLRFKVSAPSGYVRSRQAWILRQMYQLGGEPFMQQHQ
LD
>Mature_241_residues
SKSRLTVFSFVRRFLLRLMVVLAVFWGGGIALFSVAPVPFSAVMVERQVSAWLHGNFRYVAHSDWVSMDQISPWMGLAVI
AAEDQKFPEHWGFDVASIEQALAHNERNENRIRGASTISQQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTVY
LNIAEFGDGVFGVEAAAQRYFHKPASKLTRSEAALLAAVLPNPLRFKVSAPSGYVRSRQAWILRQMYQLGGEPFMQQHQL
D

Specific function: Cell wall formation [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family [H]

Homologues:

Organism=Escherichia coli, GI1789601, Length=242, Percent_Identity=99.1735537190083, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI87082258, Length=176, Percent_Identity=37.5, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1786343, Length=127, Percent_Identity=37.007874015748, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1788867, Length=144, Percent_Identity=33.3333333333333, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001264
- InterPro:   IPR011812 [H]

Pfam domain/function: PF00912 Transgly [H]

EC number: 2.4.2.- [C]

Molecular weight: Translated: 27326; Mature: 27195

Theoretical pI: Translated: 10.54; Mature: 10.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSRLTVFSFVRRFLLRLMVVLAVFWGGGIALFSVAPVPFSAVMVERQVSAWLHGNFRY
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCEEE
VAHSDWVSMDQISPWMGLAVIAAEDQKFPEHWGFDVASIEQALAHNERNENRIRGASTIS
EEECCCCCHHHCCCCCCEEEEEECCCCCCHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHH
QQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTVYLNIAEFGDGVFGVEAAAQR
HHHHCCEEEECCHHHHHHHHHCCHHHHHHHHHCCCEEEEEEEEHHHHCCCCHHHHHHHHH
YFHKPASKLTRSEAALLAAVLPNPLRFKVSAPSGYVRSRQAWILRQMYQLGGEPFMQQHQ
HHHCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHCC
LD
CC
>Mature Secondary Structure 
SKSRLTVFSFVRRFLLRLMVVLAVFWGGGIALFSVAPVPFSAVMVERQVSAWLHGNFRY
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCEEE
VAHSDWVSMDQISPWMGLAVIAAEDQKFPEHWGFDVASIEQALAHNERNENRIRGASTIS
EEECCCCCHHHCCCCCCEEEEEECCCCCCHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHH
QQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTVYLNIAEFGDGVFGVEAAAQR
HHHHCCEEEECCHHHHHHHHHCCHHHHHHHHHCCCEEEEEEEEHHHHCCCCHHHHHHHHH
YFHKPASKLTRSEAALLAAVLPNPLRFKVSAPSGYVRSRQAWILRQMYQLGGEPFMQQHQ
HHHCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHCC
LD
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA