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The map label for this gene is chuA [H]

Identifier: 170681293

GI number: 170681293

Start: 3867974

End: 3869956

Strand: Reverse

Name: chuA [H]

Synonym: EcSMS35_3802

Alternate gene names: 170681293

Gene position: 3869956-3867974 (Counterclockwise)

Preceding gene: 170680597

Following gene: 170682449

Centisome position: 76.35

GC content: 50.33

Gene sequence:

>1983_bases
ATGTCACGTCCGCAATTTACCTCGTTGCGTTTGAGTTTGTTGGCTTTGGCTGTTTCTGCCACCTTGCCAACGTTTGCTTT
TGCTACTGAAACCATGACCGTTACGGCAACGGGGAATGCACGTAGTTCCTTCGAAGCGCCTATGATGGTCAGCGTTATCG
ACACTTCCGCTCCTGAAAATCAAACGGCTACTTCAGCCACTGATTTGCTGCGTCATGTTCCTGGAATTACTCTTGATGGT
ACCGGACGAACCAACGGTCAGGATGTAAATATGCGTGGCTATGATCATCGCGGCGTGCTGGTTCTTGTCGATGGTGTTCG
CCAGGGAACGGATACCGGACACCTGAATGGCACTTTTCTCGATCCGGCGCTGATCAAGCGTGTTGAGATTGTTCGCGGAC
CTTCAGCATTACTGTATGGCAGTGGCGCGCTGGGTGGAGTGATCTCCTACGATACGGTCGATGCAAAAGATTTATTGCAG
GAAGGACAAAGCAGTGGTTTTCGTGTCTTTGGTACTGGCGGCACGGGGGACCATAGCCTGGGATTAGGCGCGAGCGCGTT
TGGGCGAACTGAAAATCTGGATGGTATTGTGGCCTGGTCCAGTCGCGATCGGGGTGATTTACGCCAGAGCAATGGTGAAA
CCGCGCCGAATGACGAGTCCATTAATAACATGCTGGCGAAAGGGACTTGGCAAATTGATTCAGCCCAGTCTCTGAGCGGT
TTAGTGCGTTACTACAACAACGACGCGCGTGAACCAAAAAATCCGCAGACTGTTGAGGCTTCTGATAGCAGCAACCCGAT
GGTTGATCGTTCAACAATTCAACGCGATGCGCAGCTTTCTTATAAACTCGCCCCGCAGGGCAACGACTGGTTAAATGCAG
ATGCAAAAATTTACTGGTCGGAAGTCCGTATTAATGCGCAAAACACGGGGAGTTCCGGCGAGTATCGTGAACAGATAACA
AAAGGAGCCAGGCTGGAGAACCGTTCCACTCTATTTGCCGACAGTTTCGCTTCTCACTTACTGACATATGGCGGTGAGTA
TTATCGTCAGGAACAACATCCGGGCGGCGCGACCACGGGCTTCCCGCAAGCAAAAATCGATTTTAGCTCTGGCTGGCTAC
AGGATGAGATCACCTTACGCGATCTGCCGATTACCCTGCTTGGCGGAACCCGCTATGACAGTTATCGCGGTAGCAGCGAC
GGCTACAAAGATGTTGATGCTGACAAATGGTCATCTCGTGCGGGGATGACTATCAACCCGACCAACTGGCTGATGTTATT
TGGCTCATATGCCCAGGCATTCCGCGCCCCGACGATGGGCGAAATGTATAACGATTCTAAGCACTTCTCGATTGGTCGCT
TCTATACCAACTATTGGGTGCCAAACCCGAACTTACGTCCGGAAACTAACGAAACTCAGGAGTACGGTTTTGGGCTGCGT
TTTGATGACCTGATGTTGTCCAATGATGCTCTGGAATTTAAAGCCAGCTACTTTGATACCAAAGCGAAGGATTACATCTC
CACGACCGTCGATTTCGCGGCGGCGACAACTATGTCGTATAACGTCCCGAACGCCAAAATCTGGGGCTGGGATGTAATGA
CGAAATATACCACTGATCTGTTTAGCCTTGATGTGGCCTATAACCGTACCCGCGGCAAAGACACCGATACTGGGGAATAT
ATCTCCAGCATTAACCCGGATACCGTTACCAGTACCCTGAATATTCCGATCGCTCACAGTGGCTTCTCTGTTGGGTGGGT
TGGTACGTTTGCCGATCGCTCAACACATATCAGCAGCAGTTACAGCAAACAACCAGGCTATGGCGTGAATGATTTCTACG
TCAGTTATCAAGGACAACAGGCGCTCAAAGGTATGACCACTACTTTGGTGTTGGGTAACGCTTTCGACAAAGAGTACTGG
TCACCACAAGGCATCCCACAGGATGGTCGTAACGGAAAAATTTTCGTGAGTTATCAATGGTAA

Upstream 100 bases:

>100_bases
TATCTAATCATTTGAATTGTAAATAAATTTATTTTTCGCCAGCCACCCCGGTATTAACCCAGGCAGCCAGCATTTTTTAT
TTTCCTCATGGAGAATCGCT

Downstream 100 bases:

>100_bases
TCATCTGCCCCGATATTTCGGGGCATTTATCTGGAAGGAAGAGAGACAATGAACCACTACACACGCTGGCTTGAGTTAAA
AGAACAAAATCCCGGAAAGT

Product: outer membrane heme/hemoglobin receptor ChuA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 660; Mature: 659

Protein sequence:

>660_residues
MSRPQFTSLRLSLLALAVSATLPTFAFATETMTVTATGNARSSFEAPMMVSVIDTSAPENQTATSATDLLRHVPGITLDG
TGRTNGQDVNMRGYDHRGVLVLVDGVRQGTDTGHLNGTFLDPALIKRVEIVRGPSALLYGSGALGGVISYDTVDAKDLLQ
EGQSSGFRVFGTGGTGDHSLGLGASAFGRTENLDGIVAWSSRDRGDLRQSNGETAPNDESINNMLAKGTWQIDSAQSLSG
LVRYYNNDAREPKNPQTVEASDSSNPMVDRSTIQRDAQLSYKLAPQGNDWLNADAKIYWSEVRINAQNTGSSGEYREQIT
KGARLENRSTLFADSFASHLLTYGGEYYRQEQHPGGATTGFPQAKIDFSSGWLQDEITLRDLPITLLGGTRYDSYRGSSD
GYKDVDADKWSSRAGMTINPTNWLMLFGSYAQAFRAPTMGEMYNDSKHFSIGRFYTNYWVPNPNLRPETNETQEYGFGLR
FDDLMLSNDALEFKASYFDTKAKDYISTTVDFAAATTMSYNVPNAKIWGWDVMTKYTTDLFSLDVAYNRTRGKDTDTGEY
ISSINPDTVTSTLNIPIAHSGFSVGWVGTFADRSTHISSSYSKQPGYGVNDFYVSYQGQQALKGMTTTLVLGNAFDKEYW
SPQGIPQDGRNGKIFVSYQW

Sequences:

>Translated_660_residues
MSRPQFTSLRLSLLALAVSATLPTFAFATETMTVTATGNARSSFEAPMMVSVIDTSAPENQTATSATDLLRHVPGITLDG
TGRTNGQDVNMRGYDHRGVLVLVDGVRQGTDTGHLNGTFLDPALIKRVEIVRGPSALLYGSGALGGVISYDTVDAKDLLQ
EGQSSGFRVFGTGGTGDHSLGLGASAFGRTENLDGIVAWSSRDRGDLRQSNGETAPNDESINNMLAKGTWQIDSAQSLSG
LVRYYNNDAREPKNPQTVEASDSSNPMVDRSTIQRDAQLSYKLAPQGNDWLNADAKIYWSEVRINAQNTGSSGEYREQIT
KGARLENRSTLFADSFASHLLTYGGEYYRQEQHPGGATTGFPQAKIDFSSGWLQDEITLRDLPITLLGGTRYDSYRGSSD
GYKDVDADKWSSRAGMTINPTNWLMLFGSYAQAFRAPTMGEMYNDSKHFSIGRFYTNYWVPNPNLRPETNETQEYGFGLR
FDDLMLSNDALEFKASYFDTKAKDYISTTVDFAAATTMSYNVPNAKIWGWDVMTKYTTDLFSLDVAYNRTRGKDTDTGEY
ISSINPDTVTSTLNIPIAHSGFSVGWVGTFADRSTHISSSYSKQPGYGVNDFYVSYQGQQALKGMTTTLVLGNAFDKEYW
SPQGIPQDGRNGKIFVSYQW
>Mature_659_residues
SRPQFTSLRLSLLALAVSATLPTFAFATETMTVTATGNARSSFEAPMMVSVIDTSAPENQTATSATDLLRHVPGITLDGT
GRTNGQDVNMRGYDHRGVLVLVDGVRQGTDTGHLNGTFLDPALIKRVEIVRGPSALLYGSGALGGVISYDTVDAKDLLQE
GQSSGFRVFGTGGTGDHSLGLGASAFGRTENLDGIVAWSSRDRGDLRQSNGETAPNDESINNMLAKGTWQIDSAQSLSGL
VRYYNNDAREPKNPQTVEASDSSNPMVDRSTIQRDAQLSYKLAPQGNDWLNADAKIYWSEVRINAQNTGSSGEYREQITK
GARLENRSTLFADSFASHLLTYGGEYYRQEQHPGGATTGFPQAKIDFSSGWLQDEITLRDLPITLLGGTRYDSYRGSSDG
YKDVDADKWSSRAGMTINPTNWLMLFGSYAQAFRAPTMGEMYNDSKHFSIGRFYTNYWVPNPNLRPETNETQEYGFGLRF
DDLMLSNDALEFKASYFDTKAKDYISTTVDFAAATTMSYNVPNAKIWGWDVMTKYTTDLFSLDVAYNRTRGKDTDTGEYI
SSINPDTVTSTLNIPIAHSGFSVGWVGTFADRSTHISSSYSKQPGYGVNDFYVSYQGQQALKGMTTTLVLGNAFDKEYWS
PQGIPQDGRNGKIFVSYQW

Specific function: This protein is involved in the initial step of iron uptake by binding hemin, an iron chelatin siderophore that allows the bacteria to extract iron from the environment [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=685, Percent_Identity=24.963503649635, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI1786798, Length=739, Percent_Identity=22.4627875507442, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790405, Length=148, Percent_Identity=33.1081081081081, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR011276
- InterPro:   IPR010949 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 72488; Mature: 72356

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPQFTSLRLSLLALAVSATLPTFAFATETMTVTATGNARSSFEAPMMVSVIDTSAPEN
CCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCCCCCEEEEEEECCCCCC
QTATSATDLLRHVPGITLDGTGRTNGQDVNMRGYDHRGVLVLVDGVRQGTDTGHLNGTFL
CCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEE
DPALIKRVEIVRGPSALLYGSGALGGVISYDTVDAKDLLQEGQSSGFRVFGTGGTGDHSL
CHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCHHHHHHHCCCCCEEEEECCCCCCCCC
GLGASAFGRTENLDGIVAWSSRDRGDLRQSNGETAPNDESINNMLAKGTWQIDSAQSLSG
CCCCHHCCCCCCCCEEEEECCCCCCCHHHCCCCCCCCHHHHHHHHHCCEEECCCHHHHHH
LVRYYNNDAREPKNPQTVEASDSSNPMVDRSTIQRDAQLSYKLAPQGNDWLNADAKIYWS
HHHHHCCCCCCCCCCCEEECCCCCCCCCCHHHHHHCCCEEEEECCCCCCCCCCCCEEEEE
EVRINAQNTGSSGEYREQITKGARLENRSTLFADSFASHLLTYGGEYYRQEQHPGGATTG
EEEEEECCCCCCCHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHCHHHHHHCCCCCCCCCC
FPQAKIDFSSGWLQDEITLRDLPITLLGGTRYDSYRGSSDGYKDVDADKWSSRAGMTINP
CCCEEEECCCCCCCCCEEEEECCEEEECCCCCCCCCCCCCCCCCCCCCHHCCCCCCEECC
TNWLMLFGSYAQAFRAPTMGEMYNDSKHFSIGRFYTNYWVPNPNLRPETNETQEYGFGLR
CCEEEEEEHHHHHHCCCCCHHHCCCCCCEEEEEEEEEEECCCCCCCCCCCCHHHHCCCCE
FDDLMLSNDALEFKASYFDTKAKDYISTTVDFAAATTMSYNVPNAKIWGWDVMTKYTTDL
EHHEEECCCCCEEEHHHCCCHHHHHHHHHHHHHEEEEEEECCCCCEEEEEHHHHHHHHHH
FSLDVAYNRTRGKDTDTGEYISSINPDTVTSTLNIPIAHSGFSVGWVGTFADRSTHISSS
EEEEEEECCCCCCCCCCHHHHHCCCCCCEEEEEECEEEECCCCEEEEEECCCCCCCCCCC
YSKQPGYGVNDFYVSYQGQQALKGMTTTLVLGNAFDKEYWSPQGIPQDGRNGKIFVSYQW
CCCCCCCCCCEEEEEECCHHHHCCCEEEEEECCCCCHHHCCCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure 
SRPQFTSLRLSLLALAVSATLPTFAFATETMTVTATGNARSSFEAPMMVSVIDTSAPEN
CCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCCCCCEEEEEEECCCCCC
QTATSATDLLRHVPGITLDGTGRTNGQDVNMRGYDHRGVLVLVDGVRQGTDTGHLNGTFL
CCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEE
DPALIKRVEIVRGPSALLYGSGALGGVISYDTVDAKDLLQEGQSSGFRVFGTGGTGDHSL
CHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCHHHHHHHCCCCCEEEEECCCCCCCCC
GLGASAFGRTENLDGIVAWSSRDRGDLRQSNGETAPNDESINNMLAKGTWQIDSAQSLSG
CCCCHHCCCCCCCCEEEEECCCCCCCHHHCCCCCCCCHHHHHHHHHCCEEECCCHHHHHH
LVRYYNNDAREPKNPQTVEASDSSNPMVDRSTIQRDAQLSYKLAPQGNDWLNADAKIYWS
HHHHHCCCCCCCCCCCEEECCCCCCCCCCHHHHHHCCCEEEEECCCCCCCCCCCCEEEEE
EVRINAQNTGSSGEYREQITKGARLENRSTLFADSFASHLLTYGGEYYRQEQHPGGATTG
EEEEEECCCCCCCHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHCHHHHHHCCCCCCCCCC
FPQAKIDFSSGWLQDEITLRDLPITLLGGTRYDSYRGSSDGYKDVDADKWSSRAGMTINP
CCCEEEECCCCCCCCCEEEEECCEEEECCCCCCCCCCCCCCCCCCCCCHHCCCCCCEECC
TNWLMLFGSYAQAFRAPTMGEMYNDSKHFSIGRFYTNYWVPNPNLRPETNETQEYGFGLR
CCEEEEEEHHHHHHCCCCCHHHCCCCCCEEEEEEEEEEECCCCCCCCCCCCHHHHCCCCE
FDDLMLSNDALEFKASYFDTKAKDYISTTVDFAAATTMSYNVPNAKIWGWDVMTKYTTDL
EHHEEECCCCCEEEHHHCCCHHHHHHHHHHHHHEEEEEEECCCCCEEEEEHHHHHHHHHH
FSLDVAYNRTRGKDTDTGEYISSINPDTVTSTLNIPIAHSGFSVGWVGTFADRSTHISSS
EEEEEEECCCCCCCCCCHHHHHCCCCCCEEEEEECEEEECCCCEEEEEECCCCCCCCCCC
YSKQPGYGVNDFYVSYQGQQALKGMTTTLVLGNAFDKEYWSPQGIPQDGRNGKIFVSYQW
CCCCCCCCCCEEEEEECCHHHHCCCEEEEEECCCCCHHHCCCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9026634; 11586360; 12142430 [H]