Click here to switch to the map view.

The map label for this gene is xlyP [H]

Identifier: 170680613

GI number: 170680613

Start: 24218

End: 25591

Strand: Reverse

Name: xlyP [H]

Synonym: EcSMS35_0020

Alternate gene names: 170680613

Gene position: 25591-24218 (Counterclockwise)

Preceding gene: 170683345

Following gene: 170681287

Centisome position: 0.5

GC content: 48.03

Gene sequence:

>1374_bases
ATGAGTTCCGTCATTGAAACTACTCAATCAACTTCATCCGATTCCTTACCTTTAATACAGCGGATTAGCTACGGCTCACT
GGATGTTGCCGGTAATCTGCTCTACTGTTTTGGCTCTACCTACATTCTTTATTTCTACACCGACGTAGCAGGGATTAGTC
TGGCGGTTGCAGGCATAATCCTACTGCTGGCGCGCATTGTAGACGGTATTGATGCGCCAGTGTGGGGAATCATTATCGAT
AAAACCCATTCGCGTTATGGAAAATGCCGTCCATGGTTTTTATGGTTACCATTACCTTTTGCTGTATTTAGTGCGCTTTC
TTTCTGGTCACCCGATATCAGCATGACAGGGAAAGCTGTTTATGCAGCAATATCGTACATGTTAGCCAGCATTCTGTTCA
CTGGGTTGAATACACCATTAAGCGCTATATTACCGCTGATGACGCTGTCACCAAAGGAACGCCTGGTATTAAACTCATAT
CGCATGACTGGTGGGCAAATTGGCGTACTATTAATGAATGCGACAGCATTGCCATTGGTCGCTTTCCTTGGTAATGGTAA
CGATAAAGCAGGCTTTATATATACTGCCATAGTCTTTGCCGTAATATCCTGTGCCTTAACGTTGTTTGCCTTTAAAAATA
TTCGCGAACTGGATACCGATAAAATACAGCAAGAACCACGACTGCCGATGAAAAAGAGTTTTTCGGCAATGAAAGGGAAC
TGGCCGTGGCTCCTGATGGTAGTGGCGAACCTTATCTTCTGGATTGCCCTACAGCAGCGCAACACTACTATTGTTTACTA
TTTAACCTACAATCTGGATCGCAAAGATCTGGTCCCGCTGGTTAACAGCCTCGCCACCATTCAGATCCTGTTTATCATTG
CCATTCCGTTCTTCAGTCGCTATCTCACCAAAACCTGGATTTGGATTACCGGGCTGCTGGTTGCGATGTTAGGCGGGGGC
CTCATGTGGCTGGCTGCCGACAGCATCCCTTTGATGATCGCCGCCTGGGTACTCGCCAATATCGGCAGCGGTATCGCCTG
TTCTATGCCTTTCGCGATGCTCGGTTTCGCCGTTGACTTTGGTCGCTGGAAAACCGGCATTAAAGCTACCGGCATTCTGA
TCGCCTTCGGCAGCACCTTCTGCATCAAGATGGGCAGTGGTATCGGTACAGCTTTCGCTGCCTTTATTATGGACAGCTTT
GGTTATATCCCCAACCAACAACAGACGGCTGCGGGGTTGGAAGGTATCAGCCTGGCATTTATCTGGGTCCCTGCGCTGCT
CTTTGCTCTCGCGGCTGTACCACTGCTCTTCTTTCGCCAGTATGAAGCGATGGAAGGTCGTATCCAACACGATCTGCAAG
CCCACAATCGTTGA

Upstream 100 bases:

>100_bases
AATCATTAATAAATATGCATTAAGGAAAGTCAGTATGTATTTGCTTAGAAAATAAAAGCTTTTTTTCTGAGACAGGCATT
CTTGTTCTGGAGAGAATATA

Downstream 100 bases:

>100_bases
ATTTAATCAACATGCCACTTGCTCCTGGGAGGAACAATTATGTCGTTTATTAAGCAAGATCCCCACCGTCTGGTCTGGCA
ACAAGACGATCGTTATCTCT

Product: xylose-proton symporter

Products: NA

Alternate protein names: Xylose transporter [H]

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MSSVIETTQSTSSDSLPLIQRISYGSLDVAGNLLYCFGSTYILYFYTDVAGISLAVAGIILLLARIVDGIDAPVWGIIID
KTHSRYGKCRPWFLWLPLPFAVFSALSFWSPDISMTGKAVYAAISYMLASILFTGLNTPLSAILPLMTLSPKERLVLNSY
RMTGGQIGVLLMNATALPLVAFLGNGNDKAGFIYTAIVFAVISCALTLFAFKNIRELDTDKIQQEPRLPMKKSFSAMKGN
WPWLLMVVANLIFWIALQQRNTTIVYYLTYNLDRKDLVPLVNSLATIQILFIIAIPFFSRYLTKTWIWITGLLVAMLGGG
LMWLAADSIPLMIAAWVLANIGSGIACSMPFAMLGFAVDFGRWKTGIKATGILIAFGSTFCIKMGSGIGTAFAAFIMDSF
GYIPNQQQTAAGLEGISLAFIWVPALLFALAAVPLLFFRQYEAMEGRIQHDLQAHNR

Sequences:

>Translated_457_residues
MSSVIETTQSTSSDSLPLIQRISYGSLDVAGNLLYCFGSTYILYFYTDVAGISLAVAGIILLLARIVDGIDAPVWGIIID
KTHSRYGKCRPWFLWLPLPFAVFSALSFWSPDISMTGKAVYAAISYMLASILFTGLNTPLSAILPLMTLSPKERLVLNSY
RMTGGQIGVLLMNATALPLVAFLGNGNDKAGFIYTAIVFAVISCALTLFAFKNIRELDTDKIQQEPRLPMKKSFSAMKGN
WPWLLMVVANLIFWIALQQRNTTIVYYLTYNLDRKDLVPLVNSLATIQILFIIAIPFFSRYLTKTWIWITGLLVAMLGGG
LMWLAADSIPLMIAAWVLANIGSGIACSMPFAMLGFAVDFGRWKTGIKATGILIAFGSTFCIKMGSGIGTAFAAFIMDSF
GYIPNQQQTAAGLEGISLAFIWVPALLFALAAVPLLFFRQYEAMEGRIQHDLQAHNR
>Mature_456_residues
SSVIETTQSTSSDSLPLIQRISYGSLDVAGNLLYCFGSTYILYFYTDVAGISLAVAGIILLLARIVDGIDAPVWGIIIDK
THSRYGKCRPWFLWLPLPFAVFSALSFWSPDISMTGKAVYAAISYMLASILFTGLNTPLSAILPLMTLSPKERLVLNSYR
MTGGQIGVLLMNATALPLVAFLGNGNDKAGFIYTAIVFAVISCALTLFAFKNIRELDTDKIQQEPRLPMKKSFSAMKGNW
PWLLMVVANLIFWIALQQRNTTIVYYLTYNLDRKDLVPLVNSLATIQILFIIAIPFFSRYLTKTWIWITGLLVAMLGGGL
MWLAADSIPLMIAAWVLANIGSGIACSMPFAMLGFAVDFGRWKTGIKATGILIAFGSTFCIKMGSGIGTAFAAFIMDSFG
YIPNQQQTAAGLEGISLAFIWVPALLFALAAVPLLFFRQYEAMEGRIQHDLQAHNR

Specific function: Responsible for transport of xylose into the cell, with the concomitant uptake of protons (symport system) [H]

COG id: COG2211

COG function: function code G; Na+/melibiose symporter and related transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:galactoside symporter (TC 2.A.2) family [H]

Homologues:

Organism=Escherichia coli, GI145693206, Length=460, Percent_Identity=28.4782608695652, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1786466, Length=448, Percent_Identity=27.2321428571429, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI48994989, Length=447, Percent_Identity=27.5167785234899, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI87082306, Length=428, Percent_Identity=28.5046728971963, Blast_Score=162, Evalue=6e-41,
Organism=Escherichia coli, GI1790561, Length=447, Percent_Identity=25.9507829977629, Blast_Score=155, Evalue=8e-39,
Organism=Escherichia coli, GI1787902, Length=426, Percent_Identity=28.169014084507, Blast_Score=140, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001927
- InterPro:   IPR018043 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50205; Mature: 50074

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVIETTQSTSSDSLPLIQRISYGSLDVAGNLLYCFGSTYILYFYTDVAGISLAVAGII
CCCHHHHHCCCCCCCCHHHHHCCCCCCCHHCCEEEEECCEEEEEEEHHHHHHHHHHHHHH
LLLARIVDGIDAPVWGIIIDKTHSRYGKCRPWFLWLPLPFAVFSALSFWSPDISMTGKAV
HHHHHHHCCCCCCEEEEEEECCCCCCCCCCCEEEEECHHHHHHHHHHHCCCCCCCCHHHH
YAAISYMLASILFTGLNTPLSAILPLMTLSPKERLVLNSYRMTGGQIGVLLMNATALPLV
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEECCHHHHHH
AFLGNGNDKAGFIYTAIVFAVISCALTLFAFKNIRELDTDKIQQEPRLPMKKSFSAMKGN
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHCCC
WPWLLMVVANLIFWIALQQRNTTIVYYLTYNLDRKDLVPLVNSLATIQILFIIAIPFFSR
CCCHHHHHHHHHHHHHEECCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLTKTWIWITGLLVAMLGGGLMWLAADSIPLMIAAWVLANIGSGIACSMPFAMLGFAVDF
HHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCCHHCHHHHHHHHHHH
GRWKTGIKATGILIAFGSTFCIKMGSGIGTAFAAFIMDSFGYIPNQQQTAAGLEGISLAF
HHHHCCCCCCEEEEEECCEEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHH
IWVPALLFALAAVPLLFFRQYEAMEGRIQHDLQAHNR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSVIETTQSTSSDSLPLIQRISYGSLDVAGNLLYCFGSTYILYFYTDVAGISLAVAGII
CCHHHHHCCCCCCCCHHHHHCCCCCCCHHCCEEEEECCEEEEEEEHHHHHHHHHHHHHH
LLLARIVDGIDAPVWGIIIDKTHSRYGKCRPWFLWLPLPFAVFSALSFWSPDISMTGKAV
HHHHHHHCCCCCCEEEEEEECCCCCCCCCCCEEEEECHHHHHHHHHHHCCCCCCCCHHHH
YAAISYMLASILFTGLNTPLSAILPLMTLSPKERLVLNSYRMTGGQIGVLLMNATALPLV
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEECCHHHHHH
AFLGNGNDKAGFIYTAIVFAVISCALTLFAFKNIRELDTDKIQQEPRLPMKKSFSAMKGN
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHCCC
WPWLLMVVANLIFWIALQQRNTTIVYYLTYNLDRKDLVPLVNSLATIQILFIIAIPFFSR
CCCHHHHHHHHHHHHHEECCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLTKTWIWITGLLVAMLGGGLMWLAADSIPLMIAAWVLANIGSGIACSMPFAMLGFAVDF
HHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCCHHCHHHHHHHHHHH
GRWKTGIKATGILIAFGSTFCIKMGSGIGTAFAAFIMDSFGYIPNQQQTAAGLEGISLAF
HHHHCCCCCCEEEEEECCEEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHH
IWVPALLFALAAVPLLFFRQYEAMEGRIQHDLQAHNR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9573180 [H]