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The map label for this gene is bacA

Identifier: 170680114

GI number: 170680114

Start: 3428827

End: 3429639

Strand: Reverse

Name: bacA

Synonym: EcSMS35_3350

Alternate gene names: 170680114

Gene position: 3429639-3428827 (Counterclockwise)

Preceding gene: 170683805

Following gene: 170681635

Centisome position: 67.67

GC content: 52.28

Gene sequence:

>813_bases
ATGCACTCGCTGCTGATAGCGGCAATATTGGGTGTGGTCGAAGGATTGACAGAATTTCTGCCGGTATCCAGCACGGGCCA
TATGATTATTGTCGGTCACTTGTTGGGGTTTGAGGGCGACACGGCGAAAACCTTTGAAGTCGTGATCCAGTTAGGATCAA
TTCTGGCAGTGGTTGTCATGTTCTGGCGACGTCTGTTTGGCCTTATTGGTATTCACTTTGGTCGCCCGTTGCAGCACGAA
GGAGAAAGCAAAGGCCGTTTAACGCTGATCCACATTTTGCTGGGGATGATTCCGGCGGTGGTACTGGGGCTGTTGTTCCA
CGACACGATTAAATCATTGTTTAACCCGATAAATGTGATGTATGCACTGGTCGTTGGCGGTCTGTTGCTGATTGCCGCTG
AATGCCTGAAGCCGAAAGAGCCGCGTGCGCCGGGTCTTGATGATATGACCTATCGTCAGGCGTTTATGATTGGCTGTTTC
CAGTGTCTGGCGCTGTGGCCGGGTTTCTCTCGCTCCGGGGCGACCATTTCAGGTGGGATGCTGATGGGCGTGAGCCGTTA
CGCTGCTTCCGAGTTCTCGTTCCTGCTGGCGGTGCCGATGATGATGGGCGCAACGGCGCTCGATCTCTACAAAAGCTGGG
GCTTCCTGACTACCGGCGATATCCCGATGTTTGCCGTTGGGTTTATCACCGCTTTTGTGGTGGCGCTGATAGCGATTAAA
ACCTTCCTGCAATTGATTAAGCGCATTTCGTTTATCCCTTTCGCCATTTATCGCTTTATTGTGGCGGCTGCGGTGTATGT
CGTGTTCTTTTGA

Upstream 100 bases:

>100_bases
ATTTTACAGCTGTTAAACCAAACGGTTATAACCTGGTCATACTGCAGTAGTTCGGACAAGCGGTACATTTTAATAATTTA
GGGGTTTATTGATGAGCGAT

Downstream 100 bases:

>100_bases
TTGAGGAATAGTGTCGGATATGACGCTTGTGCGTCTTATCCGACCTGGCCGGTGTTTGCAATAAATTGAAATTCAAGTGC
TTAATCAGGCTTTGGACAAC

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHE
GESKGRLTLIHILLGMIPAVVLGLLFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMIGCF
QCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTTGDIPMFAVGFITAFVVALIAIK
TFLQLIKRISFIPFAIYRFIVAAAVYVVFF

Sequences:

>Translated_270_residues
MHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHE
GESKGRLTLIHILLGMIPAVVLGLLFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMIGCF
QCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTTGDIPMFAVGFITAFVVALIAIK
TFLQLIKRISFIPFAIYRFIVAAAVYVVFF
>Mature_270_residues
MHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHE
GESKGRLTLIHILLGMIPAVVLGLLFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMIGCF
QCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTTGDIPMFAVGFITAFVVALIAIK
TFLQLIKRISFIPFAIYRFIVAAAVYVVFF

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=270, Percent_Identity=99.6296296296296, Blast_Score=536, Evalue=1e-154,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_ECO24 (A7ZRT8)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001464517.1
- STRING:   A7ZRT8
- EnsemblBacteria:   EBESCT00000019197
- GeneID:   5589698
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_3520
- eggNOG:   COG1968
- GeneTree:   EBGT00050000011219
- HOGENOM:   HBG391969
- OMA:   LVQCLAM
- ProtClustDB:   PRK00281
- BioCyc:   ECOL331111:ECE24377A_3520-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29440; Mature: 29440

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1c062bf4)-; HASH(0x1c5b4670)-; HASH(0x1c5b455c)-; HASH(0x1c5b4370)-; HASH(0x1c580648)-; HASH(0x1c5bb1e8)-; HASH(0x1c5bd648)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAVVVM
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHH
FWRRLFGLIGIHFGRPLQHEGESKGRLTLIHILLGMIPAVVLGLLFHDTIKSLFNPINVM
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMIGCFQCLALWPGFSRSGATISGGM
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCHH
LMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTTGDIPMFAVGFITAFVVALIAIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TFLQLIKRISFIPFAIYRFIVAAAVYVVFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA