Click here to switch to the map view.

The map label for this gene is baeS [H]

Identifier: 170680059

GI number: 170680059

Start: 990667

End: 992070

Strand: Reverse

Name: baeS [H]

Synonym: EcSMS35_0982

Alternate gene names: 170680059

Gene position: 992070-990667 (Counterclockwise)

Preceding gene: 170682817

Following gene: 170680336

Centisome position: 19.57

GC content: 54.49

Gene sequence:

>1404_bases
ATGAAGTTCTGGCGACCCGGTATTACCGGCAAACTGTTTCTGGCGATTTTCGCCACCTGCATTGTCTTATTGATCACGAT
GCACTGGGCGGTACGTATCAGTTTTGAGCGCGGCTTTATCGATTACATCAAGCATGGTAATGAACAACGGCTGCAAATGC
TCGGCGATGCGCTTGGTGAGCAGTACGCCCAGCACGGGAACTGGCGCTTCCTGCGTAATAACGATCGCTTTGTATTTCAG
ATCCTACGTTCGCTGGAGCATGATAACAACGAAGATAAGCCCGGCCCCGGTATGCCGCCACACGGTTGGCGCACGCAATT
CTGGGTGGTTGATCAAAACAACAAAGTGCTGGTTGGCCCGCGAGCACCGATTCCACCCGACGGCACACGGCGGCCCATTA
TGGTCAATGGGGCGGAAGTGGGTGCGGTGATCGCCTCCCCTGTTGAACGACTGACCCGCAATACCGATATCAATTTTGAC
AGACAACAGAGGCAAACCAGTTGGCTGATTGTCGCTTTATCTACCTTGTTAGCGGCGCTGGCGACATTCCCACTGGCGCG
CGGTTTGCTGGCTCCGGTCAAACGACTGGTGGACGGTACACACAAACTGGCAGCGGGCGATTTCACTACTCGCGTGACGC
CCACCAGTGAAGATGAATTGGGCAAACTGGCGCAAGACTTCAACCAGCTCGCCAGCACGCTGGAGAAAAACCAACAGATG
CGCCGCGATTTTATGGCCGATATCTCCCACGAGCTGCGCACGCCTTTAGCGGTACTGCGCGGCGAACTGGAAGCTATTCA
GGATGGCGTGCGTAAATTCACGCCGGAGACGGTGGCTTCTTTACAGGCAGAGGTCGGTACACTGACCAAACTGGTGGATG
ATCTTCATCAATTGTCGATGTCTGATGAAGGCGCTCTCGCCTACCAGAAATCGTCGGTGGATCTGATCCCGCTACTGGAA
GTCGCGGGTGGCGCATTTCGTGAGCGTTTCGCCAGCCGCGGGCTGAAACTGCAATTTTCCCTGCCAGACAGTATTACCGT
ATTTGGCGATCGCGACCGTTTAATGCAGTTATTCAATAACTTACTGGAAAACAGCCTGCGCTACACTGACAGCGGCGGTA
GCCTGAAAATCTCTGCCGAGCAGCACGACAAAACGGTGCGCCTGACCTTTGCCGACAGCGCGCCGGGCGTCAGTGACGAT
CAGCTACAAAAATTGTTTGAACGTTTTTATCGCACCGAAGGCTCCCGCAACCGAGCCAGCGGCGGTTCCGGGCTGGGGCT
GGCGATTTGCCTGAACATTGTTGAAGCACATAATGGTCGCATTATTGCTGCCCATTCGCCTTTTGGCGGGGTAAGCATTA
CAGTAGAGTTACCGCTGGAACGGGATTTACAGAGAGAAGTATGA

Upstream 100 bases:

>100_bases
GCATGGCGTTTATCATCGCCCTTCCGGCGTTCATCTTTGCCAGAGTGCCGAACGATACGCATCAAAATGTAGCTATTTCG
CGGCGAAAAAGGAGCGCGCA

Downstream 100 bases:

>100_bases
CCGAGTTACCAATCGACGAAAACACGCCACGTATTTTGATCGTGGAAGATGAACCGAAGCTGGGGCAGTTACTCATTGAT
TATCTGCGTGCTGCGAGCTA

Product: signal transduction histidine-protein kinase BaeS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MKFWRPGITGKLFLAIFATCIVLLITMHWAVRISFERGFIDYIKHGNEQRLQMLGDALGEQYAQHGNWRFLRNNDRFVFQ
ILRSLEHDNNEDKPGPGMPPHGWRTQFWVVDQNNKVLVGPRAPIPPDGTRRPIMVNGAEVGAVIASPVERLTRNTDINFD
RQQRQTSWLIVALSTLLAALATFPLARGLLAPVKRLVDGTHKLAAGDFTTRVTPTSEDELGKLAQDFNQLASTLEKNQQM
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETVASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKSSVDLIPLLE
VAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLKISAEQHDKTVRLTFADSAPGVSDD
QLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELPLERDLQREV

Sequences:

>Translated_467_residues
MKFWRPGITGKLFLAIFATCIVLLITMHWAVRISFERGFIDYIKHGNEQRLQMLGDALGEQYAQHGNWRFLRNNDRFVFQ
ILRSLEHDNNEDKPGPGMPPHGWRTQFWVVDQNNKVLVGPRAPIPPDGTRRPIMVNGAEVGAVIASPVERLTRNTDINFD
RQQRQTSWLIVALSTLLAALATFPLARGLLAPVKRLVDGTHKLAAGDFTTRVTPTSEDELGKLAQDFNQLASTLEKNQQM
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETVASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKSSVDLIPLLE
VAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLKISAEQHDKTVRLTFADSAPGVSDD
QLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELPLERDLQREV
>Mature_467_residues
MKFWRPGITGKLFLAIFATCIVLLITMHWAVRISFERGFIDYIKHGNEQRLQMLGDALGEQYAQHGNWRFLRNNDRFVFQ
ILRSLEHDNNEDKPGPGMPPHGWRTQFWVVDQNNKVLVGPRAPIPPDGTRRPIMVNGAEVGAVIASPVERLTRNTDINFD
RQQRQTSWLIVALSTLLAALATFPLARGLLAPVKRLVDGTHKLAAGDFTTRVTPTSEDELGKLAQDFNQLASTLEKNQQM
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETVASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKSSVDLIPLLE
VAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLKISAEQHDKTVRLTFADSAPGVSDD
QLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELPLERDLQREV

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=467, Percent_Identity=97.0021413276231, Blast_Score=901, Evalue=0.0,
Organism=Escherichia coli, GI1786783, Length=290, Percent_Identity=29.3103448275862, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1790346, Length=272, Percent_Identity=28.3088235294118, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786912, Length=276, Percent_Identity=29.7101449275362, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1786600, Length=253, Percent_Identity=27.6679841897233, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788713, Length=244, Percent_Identity=28.6885245901639, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787374, Length=299, Percent_Identity=26.0869565217391, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1790861, Length=250, Percent_Identity=30, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=27.2727272727273, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788279, Length=285, Percent_Identity=26.3157894736842, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1790551, Length=299, Percent_Identity=28.0936454849498, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787894, Length=307, Percent_Identity=23.7785016286645, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87081816, Length=254, Percent_Identity=28.3464566929134, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082128, Length=292, Percent_Identity=23.972602739726, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=27.5555555555556, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788549, Length=266, Percent_Identity=25.9398496240602, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789808, Length=245, Percent_Identity=28.1632653061224, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789403, Length=297, Percent_Identity=27.9461279461279, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1789149, Length=320, Percent_Identity=22.5, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI48994928, Length=236, Percent_Identity=24.5762711864407, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52092; Mature: 52092

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFWRPGITGKLFLAIFATCIVLLITMHWAVRISFERGFIDYIKHGNEQRLQMLGDALGE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHCCCHHHHHHHHHHHHH
QYAQHGNWRFLRNNDRFVFQILRSLEHDNNEDKPGPGMPPHGWRTQFWVVDQNNKVLVGP
HHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEECC
RAPIPPDGTRRPIMVNGAEVGAVIASPVERLTRNTDINFDRQQRQTSWLIVALSTLLAAL
CCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ATFPLARGLLAPVKRLVDGTHKLAAGDFTTRVTPTSEDELGKLAQDFNQLASTLEKNQQM
HHHHHHHHHHHHHHHHHCCHHHEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETVASLQAEVGTLTKLVDDLHQLSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
SDEGALAYQKSSVDLIPLLEVAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNN
CCCCCEEEECCCCCHHHHHHHCCHHHHHHHHHCCCEEEEECCCCEEEECCHHHHHHHHHH
LLENSLRYTDSGGSLKISAEQHDKTVRLTFADSAPGVSDDQLQKLFERFYRTEGSRNRAS
HHHHCCEEECCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCC
GGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELPLERDLQREV
CCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCHHHHCCC
>Mature Secondary Structure
MKFWRPGITGKLFLAIFATCIVLLITMHWAVRISFERGFIDYIKHGNEQRLQMLGDALGE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHCCCHHHHHHHHHHHHH
QYAQHGNWRFLRNNDRFVFQILRSLEHDNNEDKPGPGMPPHGWRTQFWVVDQNNKVLVGP
HHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEECC
RAPIPPDGTRRPIMVNGAEVGAVIASPVERLTRNTDINFDRQQRQTSWLIVALSTLLAAL
CCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ATFPLARGLLAPVKRLVDGTHKLAAGDFTTRVTPTSEDELGKLAQDFNQLASTLEKNQQM
HHHHHHHHHHHHHHHHHCCHHHEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETVASLQAEVGTLTKLVDDLHQLSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
SDEGALAYQKSSVDLIPLLEVAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNN
CCCCCEEEECCCCCHHHHHHHCCHHHHHHHHHCCCEEEEECCCCEEEECCHHHHHHHHHH
LLENSLRYTDSGGSLKISAEQHDKTVRLTFADSAPGVSDDQLQKLFERFYRTEGSRNRAS
HHHHCCEEECCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCC
GGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELPLERDLQREV
CCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]