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The map label for this gene is walK [H]

Identifier: 170079169

GI number: 170079169

Start: 2689447

End: 2691249

Strand: Reverse

Name: walK [H]

Synonym: SYNPCC7002_A2575

Alternate gene names: 170079169

Gene position: 2691249-2689447 (Counterclockwise)

Preceding gene: 170079170

Following gene: 170079167

Centisome position: 89.47

GC content: 52.63

Gene sequence:

>1803_bases
ATGGTCTCCGCTGCCCTCTACGACTGCTTAGAATTTGGCATCTCATCCCCGCGCCTTTTAACCCGCCTAACGGCGGCGAT
CGCCCAGCAGTTACAGGTGGATTGGGTTTGTTTGAGGGTCGATTTAAGCCCATCCCAAAGCCTCACCGAGACCTGGCCCA
CGAACCTAGCCGATGTCAATCTTGTTCTACCCCAAGAATTTCATCCTGACATTTGCACCTATACCGATTTACGTCACACG
CCTTACCACGCTCTGATGGCCCAGGGTCTGGAGGCGATCGCCACTGTGCCCCTCCCCGCACAGCAGGCCCAGGGTTATCT
ATGGCTCGGTTGTCAGTCCCAAACCTTACCCCAGATAAATACCCTTGAGGCACTCCGCCCACCGCTCCAGTTGGCCCTTG
GAATCTTGGCCCAGCAAAACCGCATCGTCAACTGCCAACAGTACCAACAGGCCCAGCGGGAAATTCAGCAGCTCATTGAT
GAAATTCAGGACACACAAAAATTATTTCAGGCCGCCAGTACCCAACTCCAAACAATTTTCGGCGTCGAGCAGGGAGGTAT
CCTTTTACTCAAATCGGCAAATCCCCTCCGTCAACGACAGGAACCTGATCCGACGGATACTTTGGAGCTCAAGTCTAGCT
GGTCTGAGCTGCCGACCCAATGGTCGCTCCAGGACTGTGAACTCTGTCAGGTGGCTTGGCAAAAAGCGCCTCTGGTGTGG
GTGATCGCCGATACCACAACCCATCCCTGGCAATCTCCTCTCCTGGGATCCCCAGTTCGTAGCCTATTATTTGCTCCGTT
AATGGGTGGGCAACTGTCTTCCCAGCACAGTCAACCAGTCTTAGGCTTTGTGATTTTGGCCCAGCGATCGCCCCGACAAT
GGCTCCCCGAAGAAATTCAAACCATGGCCAGCATTGCTCACCAATTGGGCCGTACGATGATCCACCACCAGGCCCTCCGG
CAGGTGCAATCCCTGGTCGAAGAACGCACGAGTCAATTGAAATGGAGCCTTGAAGTCCAGGCGAAACTTAGTCAACAGAT
GCGGCACCAAATTCAACAACTGCGGCACCTTAATCGCTTGAAGGATGATTTTTTGAGTACTGTTAGTCATGAACTCAATA
CTCCCCTGGCAACGATGAAGCTGGCGATTAAAATGCTCAAACAACCGGGGCGATCGCCAGAAAAACAACGGACTTATTTA
AACATTCTCGATCAAGAACTCAACCGAGAAAGCAAACTCATCCACGACCTGCTCCAGCTCCAACAGGCAGAGGCCAGTGA
ATTTGCCCTCAAACCCCAACGCCTCGCCCTCGGCCCGGCCCTCTCAGAGCTTGTGCAAAAATTCCAAGATCGCTGGACTC
CCCTCAAACAACTCCAGTTTCACCTCCGGTTTAAGCCCAAGGCTCTCAGCACAAAATTGCAATTTGAGACGGATCCAGAA
CAATTTCTCAATGCCATGAGTGAACTCCTCACCAATGCCGGGAAATATGCCACCCCCAAGAGTAACGTTACCCTCAGCGT
TGAATATTTGGGGCGATCGCCCGCCCGGATTCAAATTCGCCTTTGTAACGATGGGGCCGCCATCCACACCGAAGAACAAT
CCCAGATTTTTGATAAATTTCGTCGGGGCACCGGGGCCACAGCCCAGGCCATTCCTGGTACTGGTCTTGGTCTCGCCCTC
GTGAAAACCATTGTTGAACATTTAGAAGGTAGCATTACCGTTTCTAGTGACCCCAATCCTCACCGCAATGATTACCGCAC
GTGCTTTCTATTGGATTTTCCCCAGGCGATCGCCGGGTTTTAA

Upstream 100 bases:

>100_bases
TTTTGGAAAAGTTTTTGGCGGTGGAGTCAGAAGCCCTAGAGAATGATTCTGAGGATGACGGGGAAGAATAAAAGTAGAGC
AAGATATTTCAGGCGAAACC

Downstream 100 bases:

>100_bases
CAGGCGGATTTTTAGATCAATATAATTAACGACTTACTCCTCTGCATCCACGGTTTGGGGCACAAGCCTCGGGTAAGGCA
GACCTTGGTGGGCGAAGGCT

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 600; Mature: 600

Protein sequence:

>600_residues
MVSAALYDCLEFGISSPRLLTRLTAAIAQQLQVDWVCLRVDLSPSQSLTETWPTNLADVNLVLPQEFHPDICTYTDLRHT
PYHALMAQGLEAIATVPLPAQQAQGYLWLGCQSQTLPQINTLEALRPPLQLALGILAQQNRIVNCQQYQQAQREIQQLID
EIQDTQKLFQAASTQLQTIFGVEQGGILLLKSANPLRQRQEPDPTDTLELKSSWSELPTQWSLQDCELCQVAWQKAPLVW
VIADTTTHPWQSPLLGSPVRSLLFAPLMGGQLSSQHSQPVLGFVILAQRSPRQWLPEEIQTMASIAHQLGRTMIHHQALR
QVQSLVEERTSQLKWSLEVQAKLSQQMRHQIQQLRHLNRLKDDFLSTVSHELNTPLATMKLAIKMLKQPGRSPEKQRTYL
NILDQELNRESKLIHDLLQLQQAEASEFALKPQRLALGPALSELVQKFQDRWTPLKQLQFHLRFKPKALSTKLQFETDPE
QFLNAMSELLTNAGKYATPKSNVTLSVEYLGRSPARIQIRLCNDGAAIHTEEQSQIFDKFRRGTGATAQAIPGTGLGLAL
VKTIVEHLEGSITVSSDPNPHRNDYRTCFLLDFPQAIAGF

Sequences:

>Translated_600_residues
MVSAALYDCLEFGISSPRLLTRLTAAIAQQLQVDWVCLRVDLSPSQSLTETWPTNLADVNLVLPQEFHPDICTYTDLRHT
PYHALMAQGLEAIATVPLPAQQAQGYLWLGCQSQTLPQINTLEALRPPLQLALGILAQQNRIVNCQQYQQAQREIQQLID
EIQDTQKLFQAASTQLQTIFGVEQGGILLLKSANPLRQRQEPDPTDTLELKSSWSELPTQWSLQDCELCQVAWQKAPLVW
VIADTTTHPWQSPLLGSPVRSLLFAPLMGGQLSSQHSQPVLGFVILAQRSPRQWLPEEIQTMASIAHQLGRTMIHHQALR
QVQSLVEERTSQLKWSLEVQAKLSQQMRHQIQQLRHLNRLKDDFLSTVSHELNTPLATMKLAIKMLKQPGRSPEKQRTYL
NILDQELNRESKLIHDLLQLQQAEASEFALKPQRLALGPALSELVQKFQDRWTPLKQLQFHLRFKPKALSTKLQFETDPE
QFLNAMSELLTNAGKYATPKSNVTLSVEYLGRSPARIQIRLCNDGAAIHTEEQSQIFDKFRRGTGATAQAIPGTGLGLAL
VKTIVEHLEGSITVSSDPNPHRNDYRTCFLLDFPQAIAGF
>Mature_600_residues
MVSAALYDCLEFGISSPRLLTRLTAAIAQQLQVDWVCLRVDLSPSQSLTETWPTNLADVNLVLPQEFHPDICTYTDLRHT
PYHALMAQGLEAIATVPLPAQQAQGYLWLGCQSQTLPQINTLEALRPPLQLALGILAQQNRIVNCQQYQQAQREIQQLID
EIQDTQKLFQAASTQLQTIFGVEQGGILLLKSANPLRQRQEPDPTDTLELKSSWSELPTQWSLQDCELCQVAWQKAPLVW
VIADTTTHPWQSPLLGSPVRSLLFAPLMGGQLSSQHSQPVLGFVILAQRSPRQWLPEEIQTMASIAHQLGRTMIHHQALR
QVQSLVEERTSQLKWSLEVQAKLSQQMRHQIQQLRHLNRLKDDFLSTVSHELNTPLATMKLAIKMLKQPGRSPEKQRTYL
NILDQELNRESKLIHDLLQLQQAEASEFALKPQRLALGPALSELVQKFQDRWTPLKQLQFHLRFKPKALSTKLQFETDPE
QFLNAMSELLTNAGKYATPKSNVTLSVEYLGRSPARIQIRLCNDGAAIHTEEQSQIFDKFRRGTGATAQAIPGTGLGLAL
VKTIVEHLEGSITVSSDPNPHRNDYRTCFLLDFPQAIAGF

Specific function: Member of the two-component regulatory system walK/walR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism. WalK functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=328, Percent_Identity=24.0853658536585, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1786783, Length=273, Percent_Identity=27.1062271062271, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082128, Length=247, Percent_Identity=25.5060728744939, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788713, Length=245, Percent_Identity=24.4897959183673, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=26.0330578512397, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788393, Length=241, Percent_Identity=24.896265560166, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1786912, Length=311, Percent_Identity=24.7588424437299, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=221, Percent_Identity=28.0542986425339, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=24.6696035242291, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67626; Mature: 67626

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSAALYDCLEFGISSPRLLTRLTAAIAQQLQVDWVCLRVDLSPSQSLTETWPTNLADVN
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCEEEEEEEEECCCCCCHHHHCCCCCCCEE
LVLPQEFHPDICTYTDLRHTPYHALMAQGLEAIATVPLPAQQAQGYLWLGCQSQTLPQIN
EECCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHCCCCCHHHCCCEEEECCCCCCCCCCH
TLEALRPPLQLALGILAQQNRIVNCQQYQQAQREIQQLIDEIQDTQKLFQAASTQLQTIF
HHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVEQGGILLLKSANPLRQRQEPDPTDTLELKSSWSELPTQWSLQDCELCQVAWQKAPLVW
EECCCCEEEEECCCHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEE
VIADTTTHPWQSPLLGSPVRSLLFAPLMGGQLSSQHSQPVLGFVILAQRSPRQWLPEEIQ
EEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHH
TMASIAHQLGRTMIHHQALRQVQSLVEERTSQLKWSLEVQAKLSQQMRHQIQQLRHLNRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHH
KDDFLSTVSHELNTPLATMKLAIKMLKQPGRSPEKQRTYLNILDQELNRESKLIHDLLQL
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHH
QQAEASEFALKPQRLALGPALSELVQKFQDRWTPLKQLQFHLRFKPKALSTKLQFETDPE
HHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHEECCHHHCCEEECCCCHH
QFLNAMSELLTNAGKYATPKSNVTLSVEYLGRSPARIQIRLCNDGAAIHTEEQSQIFDKF
HHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCEEECCHHHHHHHHH
RRGTGATAQAIPGTGLGLALVKTIVEHLEGSITVSSDPNPHRNDYRTCFLLDFPQAIAGF
HCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEEEECHHHHCCC
>Mature Secondary Structure
MVSAALYDCLEFGISSPRLLTRLTAAIAQQLQVDWVCLRVDLSPSQSLTETWPTNLADVN
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCEEEEEEEEECCCCCCHHHHCCCCCCCEE
LVLPQEFHPDICTYTDLRHTPYHALMAQGLEAIATVPLPAQQAQGYLWLGCQSQTLPQIN
EECCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHCCCCCHHHCCCEEEECCCCCCCCCCH
TLEALRPPLQLALGILAQQNRIVNCQQYQQAQREIQQLIDEIQDTQKLFQAASTQLQTIF
HHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVEQGGILLLKSANPLRQRQEPDPTDTLELKSSWSELPTQWSLQDCELCQVAWQKAPLVW
EECCCCEEEEECCCHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEE
VIADTTTHPWQSPLLGSPVRSLLFAPLMGGQLSSQHSQPVLGFVILAQRSPRQWLPEEIQ
EEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHH
TMASIAHQLGRTMIHHQALRQVQSLVEERTSQLKWSLEVQAKLSQQMRHQIQQLRHLNRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHH
KDDFLSTVSHELNTPLATMKLAIKMLKQPGRSPEKQRTYLNILDQELNRESKLIHDLLQL
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHH
QQAEASEFALKPQRLALGPALSELVQKFQDRWTPLKQLQFHLRFKPKALSTKLQFETDPE
HHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHEECCHHHCCEEECCCCHH
QFLNAMSELLTNAGKYATPKSNVTLSVEYLGRSPARIQIRLCNDGAAIHTEEQSQIFDKF
HHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCEEECCHHHHHHHHH
RRGTGATAQAIPGTGLGLALVKTIVEHLEGSITVSSDPNPHRNDYRTCFLLDFPQAIAGF
HCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEEEECHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA