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The map label for this gene is sdhA [H]

Identifier: 170079163

GI number: 170079163

Start: 2676593

End: 2678320

Strand: Reverse

Name: sdhA [H]

Synonym: SYNPCC7002_A2569

Alternate gene names: 170079163

Gene position: 2678320-2676593 (Counterclockwise)

Preceding gene: 170079167

Following gene: 170079160

Centisome position: 89.04

GC content: 50.41

Gene sequence:

>1728_bases
ATGTTGCAACACGACGTCATTATTGTCGGTGGTGGTTTGGCTGGCTGCCGTGCTGCCCTTGAGATTAAAAAGAAAAATCC
AAACTTTGATGTGGGACTCGTCGCGAAAACCCACCCGATCCGCTCCCATTCTGTGGCGGCCCAGGGGGGGATTGCCGCCA
GCTTAAAAAATGTTGACCCAGAAGATAACTGGGAAGCCCACGCCTTCGATACCGTCAAAGGTTCTGATTACCTCGCCGAT
CAAGATGCCGTCGAAATCTTAACGAAAGAAGCCCCCGACGTAATCATTGAGTTGGAACATTTAGGGGTATTATTTTCGCG
CCTCGAAGATGGTCGCATTGCCCAGCGCGCCTTCGGGGGTCATTCCCATAAGCGCACCTGCTATGCCGCCGACAAAACGG
GACATGCCATTCTCCATGAATTAGTAAATAATCTGCGGCGTAATGGGGTCAACATCTACGATGAATGGTACGTGATGAAC
CTGATCTTTGAGGAGAATCAGGCGAAGGGGATTGTCATGTATCACATCGAAACTGGACATTTAGAAATTGTCCAAACGAA
GGCCGTGATGTTTGCAACGGGGGGCTATGGCCGGGTGTTTAACACCACCTCCAATGATTTTGCTTCCACCGGAGACGGTT
TAGCGATGACGGCGGCGGTGGGGTTGCCCTTAGAAGATATGGAATTTGTGCAGTTCCATCCGACCGGACTTTTTCCTGTC
GGTGTTTTAATCTCGGAGGCGGTGCGGGGAGAAGGAGCTTACTTGCGTAATAGCGACGGCGATCGCTTTATGGAAAAGTA
CGCCCCGAAGCAGATGGAATTGGCCCCACGGGATATTACTTCCCGGGCGATTACCCTAGAAATTCGGGCAGGACGAGGAA
TTCATCCCGATGGCAGTGCCGGGGGAAATTTTGTCCATCTCGACCTGACTCACATGGGCAAGGAAAAAATTATGGAGCGG
GTGCCCTTTTGTTGGGAAGAAGCCCACCGTCTTGTCGGCGTTGATGCCATTAATGAACCGATGCCTGTGCGTCCCACGGC
TCACTATTCCATGGGCGGCATCCCCGTGAATACCGATGGTCGGGTGCGGCGCAATGGTACCGAATTAACCGAGGGCTTTT
TTGCGGCAGGGGAATGTGCCTGTGTCTCCGTCCATGGAGCCAACCGTCTCGGCAGTAATTCCCTTTTAGAATGTGTGGTT
TATGGCCAGCGGGTCGGTGGCAAGATTGCCGATTATATTGGCGATCGCCCTTTCCCAGAGATTAACGAACAACAATATTT
AGACGAAGCGAAAAATCGCATTGGTCAGCTCCTCAATCAATCCGGCAATCTGCGCATCCATAATCTCAGGCAGCAGTTTC
AAGACGCCATGAGCGACCATTGTGGTGTCTTTAGAACCGAGGCAACCATGGCGGCAGGGCTAGAACAAATTCAACATCTT
AAGGATCAATACAATCATCTTTTTCTCGATGACAAAGATATCCATTGGAATACAGAACTGATTGAAGCCCTAGAGTTACA
GAGCATTTTAAAAGTCGGAGAAGCCATTCTTACCTCTGCTTACCACCGCAAAGAAAGCCGGGGGGCGCACTCCAGGGAAG
ATTTCCCCACCAGGGATGATCAAACCTATCTAGCCCATACCCTAAGTTTCTGCAACGACACAGGTGTAACGATTGAGTAT
ATGCCCGTTGTCATTAATCGTTTTGAACCCAAAGAGCGCAAGTATTAA

Upstream 100 bases:

>100_bases
CTTGATCAGGAGAGAGAGATGTAAAAAACCGTAAGGGCGATCGCCTTTCTCCCCGACCTCTAACCCACAATAGAAAGAAT
AACCCCTGAGTTTTGTGGAT

Downstream 100 bases:

>100_bases
AGCCCTCAGCCCTTCTCAAAGATGGTGCTGTGGCATGTTCCCCAAGAATACGGATTGAGGTTCCTTAGAAAAGACTTACC
ACGTCAAGGGAAGCGTCACC

Product: succinate dehydrogenase flavoprotein subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 575; Mature: 575

Protein sequence:

>575_residues
MLQHDVIIVGGGLAGCRAALEIKKKNPNFDVGLVAKTHPIRSHSVAAQGGIAASLKNVDPEDNWEAHAFDTVKGSDYLAD
QDAVEILTKEAPDVIIELEHLGVLFSRLEDGRIAQRAFGGHSHKRTCYAADKTGHAILHELVNNLRRNGVNIYDEWYVMN
LIFEENQAKGIVMYHIETGHLEIVQTKAVMFATGGYGRVFNTTSNDFASTGDGLAMTAAVGLPLEDMEFVQFHPTGLFPV
GVLISEAVRGEGAYLRNSDGDRFMEKYAPKQMELAPRDITSRAITLEIRAGRGIHPDGSAGGNFVHLDLTHMGKEKIMER
VPFCWEEAHRLVGVDAINEPMPVRPTAHYSMGGIPVNTDGRVRRNGTELTEGFFAAGECACVSVHGANRLGSNSLLECVV
YGQRVGGKIADYIGDRPFPEINEQQYLDEAKNRIGQLLNQSGNLRIHNLRQQFQDAMSDHCGVFRTEATMAAGLEQIQHL
KDQYNHLFLDDKDIHWNTELIEALELQSILKVGEAILTSAYHRKESRGAHSREDFPTRDDQTYLAHTLSFCNDTGVTIEY
MPVVINRFEPKERKY

Sequences:

>Translated_575_residues
MLQHDVIIVGGGLAGCRAALEIKKKNPNFDVGLVAKTHPIRSHSVAAQGGIAASLKNVDPEDNWEAHAFDTVKGSDYLAD
QDAVEILTKEAPDVIIELEHLGVLFSRLEDGRIAQRAFGGHSHKRTCYAADKTGHAILHELVNNLRRNGVNIYDEWYVMN
LIFEENQAKGIVMYHIETGHLEIVQTKAVMFATGGYGRVFNTTSNDFASTGDGLAMTAAVGLPLEDMEFVQFHPTGLFPV
GVLISEAVRGEGAYLRNSDGDRFMEKYAPKQMELAPRDITSRAITLEIRAGRGIHPDGSAGGNFVHLDLTHMGKEKIMER
VPFCWEEAHRLVGVDAINEPMPVRPTAHYSMGGIPVNTDGRVRRNGTELTEGFFAAGECACVSVHGANRLGSNSLLECVV
YGQRVGGKIADYIGDRPFPEINEQQYLDEAKNRIGQLLNQSGNLRIHNLRQQFQDAMSDHCGVFRTEATMAAGLEQIQHL
KDQYNHLFLDDKDIHWNTELIEALELQSILKVGEAILTSAYHRKESRGAHSREDFPTRDDQTYLAHTLSFCNDTGVTIEY
MPVVINRFEPKERKY
>Mature_575_residues
MLQHDVIIVGGGLAGCRAALEIKKKNPNFDVGLVAKTHPIRSHSVAAQGGIAASLKNVDPEDNWEAHAFDTVKGSDYLAD
QDAVEILTKEAPDVIIELEHLGVLFSRLEDGRIAQRAFGGHSHKRTCYAADKTGHAILHELVNNLRRNGVNIYDEWYVMN
LIFEENQAKGIVMYHIETGHLEIVQTKAVMFATGGYGRVFNTTSNDFASTGDGLAMTAAVGLPLEDMEFVQFHPTGLFPV
GVLISEAVRGEGAYLRNSDGDRFMEKYAPKQMELAPRDITSRAITLEIRAGRGIHPDGSAGGNFVHLDLTHMGKEKIMER
VPFCWEEAHRLVGVDAINEPMPVRPTAHYSMGGIPVNTDGRVRRNGTELTEGFFAAGECACVSVHGANRLGSNSLLECVV
YGQRVGGKIADYIGDRPFPEINEQQYLDEAKNRIGQLLNQSGNLRIHNLRQQFQDAMSDHCGVFRTEATMAAGLEQIQHL
KDQYNHLFLDDKDIHWNTELIEALELQSILKVGEAILTSAYHRKESRGAHSREDFPTRDDQTYLAHTLSFCNDTGVTIEY
MPVVINRFEPKERKY

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG1053

COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=568, Percent_Identity=43.4859154929577, Blast_Score=454, Evalue=1e-128,
Organism=Escherichia coli, GI1786942, Length=592, Percent_Identity=42.9054054054054, Blast_Score=431, Evalue=1e-122,
Organism=Escherichia coli, GI1790597, Length=565, Percent_Identity=39.8230088495575, Blast_Score=383, Evalue=1e-107,
Organism=Escherichia coli, GI1788928, Length=549, Percent_Identity=32.6047358834244, Blast_Score=243, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI17550100, Length=579, Percent_Identity=40.9326424870466, Blast_Score=436, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI17505833, Length=526, Percent_Identity=43.9163498098859, Blast_Score=435, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI71986328, Length=432, Percent_Identity=27.5462962962963, Blast_Score=95, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322416, Length=561, Percent_Identity=43.8502673796791, Blast_Score=465, Evalue=1e-132,
Organism=Saccharomyces cerevisiae, GI6322701, Length=563, Percent_Identity=42.0959147424512, Blast_Score=462, Evalue=1e-131,
Organism=Saccharomyces cerevisiae, GI6322511, Length=485, Percent_Identity=26.8041237113402, Blast_Score=111, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6320788, Length=311, Percent_Identity=29.903536977492, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17137288, Length=568, Percent_Identity=42.4295774647887, Blast_Score=454, Evalue=1e-128,
Organism=Drosophila melanogaster, GI24655642, Length=568, Percent_Identity=42.4295774647887, Blast_Score=454, Evalue=1e-128,
Organism=Drosophila melanogaster, GI24655647, Length=568, Percent_Identity=42.4295774647887, Blast_Score=454, Evalue=1e-128,
Organism=Drosophila melanogaster, GI24663005, Length=571, Percent_Identity=39.0542907180385, Blast_Score=409, Evalue=1e-114,

Paralogues:

None

Copy number: 1900 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1360 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 1100 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR003952
- InterPro:   IPR015939
- InterPro:   IPR004112
- InterPro:   IPR011281
- InterPro:   IPR014006 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF02910 Succ_DH_flav_C [H]

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 63891; Mature: 63891

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00504 FRD_SDH_FAD_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQHDVIIVGGGLAGCRAALEIKKKNPNFDVGLVAKTHPIRSHSVAAQGGIAASLKNVDP
CCCCCEEEEECCHHHHHEEEEEECCCCCCCEEEEEECCCCCCCCCHHCCCCHHHHCCCCC
EDNWEAHAFDTVKGSDYLADQDAVEILTKEAPDVIIELEHLGVLFSRLEDGRIAQRAFGG
CCCCCCEEEECCCCCCCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCHHHHHHHCC
HSHKRTCYAADKTGHAILHELVNNLRRNGVNIYDEWYVMNLIFEENQAKGIVMYHIETGH
CCCCCEEEECCCCHHHHHHHHHHHHHHCCCCEEECEEEEEEEEECCCCCEEEEEEEECCC
LEIVQTKAVMFATGGYGRVFNTTSNDFASTGDGLAMTAAVGLPLEDMEFVQFHPTGLFPV
EEEEEEEEEEEEECCCCEEECCCCCCCCCCCCCEEEEEEECCCCCCCCEEEECCCCCCHH
GVLISEAVRGEGAYLRNSDGDRFMEKYAPKQMELAPRDITSRAITLEIRAGRGIHPDGSA
HHHHHHHHCCCCCEEECCCCHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCC
GGNFVHLDLTHMGKEKIMERVPFCWEEAHRLVGVDAINEPMPVRPTAHYSMGGIPVNTDG
CCCEEEEEHHHCCHHHHHHHCCCCHHHHHHEECCCCCCCCCCCCCCCCCCCCCEEECCCC
RVRRNGTELTEGFFAAGECACVSVHGANRLGSNSLLECVVYGQRVGGKIADYIGDRPFPE
CEECCCCHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCC
INEQQYLDEAKNRIGQLLNQSGNLRIHNLRQQFQDAMSDHCGVFRTEATMAAGLEQIQHL
CCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHH
KDQYNHLFLDDKDIHWNTELIEALELQSILKVGEAILTSAYHRKESRGAHSREDFPTRDD
HHHHCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
QTYLAHTLSFCNDTGVTIEYMPVVINRFEPKERKY
CHHHHHHHHHHCCCCCEEEEEEEHHCCCCCHHCCC
>Mature Secondary Structure
MLQHDVIIVGGGLAGCRAALEIKKKNPNFDVGLVAKTHPIRSHSVAAQGGIAASLKNVDP
CCCCCEEEEECCHHHHHEEEEEECCCCCCCEEEEEECCCCCCCCCHHCCCCHHHHCCCCC
EDNWEAHAFDTVKGSDYLADQDAVEILTKEAPDVIIELEHLGVLFSRLEDGRIAQRAFGG
CCCCCCEEEECCCCCCCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCHHHHHHHCC
HSHKRTCYAADKTGHAILHELVNNLRRNGVNIYDEWYVMNLIFEENQAKGIVMYHIETGH
CCCCCEEEECCCCHHHHHHHHHHHHHHCCCCEEECEEEEEEEEECCCCCEEEEEEEECCC
LEIVQTKAVMFATGGYGRVFNTTSNDFASTGDGLAMTAAVGLPLEDMEFVQFHPTGLFPV
EEEEEEEEEEEEECCCCEEECCCCCCCCCCCCCEEEEEEECCCCCCCCEEEECCCCCCHH
GVLISEAVRGEGAYLRNSDGDRFMEKYAPKQMELAPRDITSRAITLEIRAGRGIHPDGSA
HHHHHHHHCCCCCEEECCCCHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCC
GGNFVHLDLTHMGKEKIMERVPFCWEEAHRLVGVDAINEPMPVRPTAHYSMGGIPVNTDG
CCCEEEEEHHHCCHHHHHHHCCCCHHHHHHEECCCCCCCCCCCCCCCCCCCCCEEECCCC
RVRRNGTELTEGFFAAGECACVSVHGANRLGSNSLLECVVYGQRVGGKIADYIGDRPFPE
CEECCCCHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCC
INEQQYLDEAKNRIGQLLNQSGNLRIHNLRQQFQDAMSDHCGVFRTEATMAAGLEQIQHL
CCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHH
KDQYNHLFLDDKDIHWNTELIEALELQSILKVGEAILTSAYHRKESRGAHSREDFPTRDD
HHHHCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
QTYLAHTLSFCNDTGVTIEYMPVVINRFEPKERKY
CHHHHHHHHHHCCCCCEEEEEEEHHCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA