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The map label for this gene is mltA [H]

Identifier: 170078965

GI number: 170078965

Start: 2451352

End: 2452500

Strand: Reverse

Name: mltA [H]

Synonym: SYNPCC7002_A2370

Alternate gene names: 170078965

Gene position: 2452500-2451352 (Counterclockwise)

Preceding gene: 170078976

Following gene: 170078962

Centisome position: 81.53

GC content: 52.39

Gene sequence:

>1149_bases
ATGAAAATTTTTTGGTCAGGTCTAACCATTGCCACCCTGGGCACCATCGCAAGTGTAGTCAGTCAGCCGGGCCTTACCCA
AGTGCTCCAGCCGACCACAACGCCAGGGGCGATCGCCTTACCGGATTACGGCCTGTGGCAAAACCAAGAACGCCAAAAGT
TACTCAACGCCATCGACCATAGCCTGCGCTACATCGACACCAATACCGCCCAAGCGGATTATGCAGCGGTACAAGTCCCC
GGCTTCAGTCGAGAAAAGGTGCGGCGATCGCTGGTACGATTTCGGCAGTTAGTGCAACAATATCCCGACCCCCGCCAATT
ACACCAAGCGATCCAGCGAGAATTTATTTTCTATCGCTCTGTGGGTAAAGATGGCACGGGCCAGGTGGACTTTACCGCTT
ACTTTGAACCAGCCTACGTTGCCAGCCCCGTTAAAACTAACGAATTTCAATATCCCCTCTATCGTCAGCCCCCCGGTTTT
AAAACTTGGTCGCAACCCCACCCCCGCCGTGTAGCCTTAGAAGGCCGTGATGGTATTCCGCCGAGCGATAGTCCCTTGCG
GGGGCATGAATTGGTTTGGTTAAAAAGTCGCCTCGAAGCCTATCTGATCCAGGTGCAAGGTTCCGCCCGGTTGCAACTGA
CCAATGGCCGCACCATGACCATTGGTTTTGATGGCAGTACCGATTATGAATATGTCAGCTTGGGCAAGGAGTTGATTAAC
GAGGGCATTTTTCAGCCAGAAGAATTAAGCCTCCCCAAATTAATTGACTATTTTGAGGCGAATCCCACAGAACTCAGTAA
TTACATTCCTCGCAATAATCGCTTTATCTTTTTCCGGGAAACTTTCGGGTCGCCGCCCATCGGTAGTATCGGGGTGCCCG
TCTTAGCAGAGCGATCAATTGCCACCGACAAAAGTATTTTTCCCCCAGGGGCGATCGCCTTTATTGCGACCCAGCTTCCT
TACCAGCGGGCCAATGGAGACTGGTTAAAACTCCCCGTCAGTCGTTATGTCCTCGATCAAGACACAGGCAGCGCGATCAA
AGGGGCTGGCCGGGTTGATATTTTCCTCGGCACCGGGCCAAACACCCAAACCCGCGCTGGTCTCGTCAACGATCCGGGTA
ATCTTTACTATCTCCTCCTCAAGGATTAA

Upstream 100 bases:

>100_bases
CATAGGTGGCGATCGCCTATGGCCTGACGCAATCGGGAGATTCCTAGGCTTCGAGTTACAATGGCAAAACTCTGTGGGGC
GTCTAAGGAAAGAAGATATT

Downstream 100 bases:

>100_bases
GCCTCGCCTAATTTCTCGATCAAAAATCCCCCTAAATTTTTTCATCTAGGGGGACTGAATCTTAAGGTTTAAAAGCGTGT
TAAATATCAACAACGGCCTT

Product: membrane-bound lytic transglycosylase A

Products: Muramic Acid Residue [C]

Alternate protein names: Murein hydrolase A [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MKIFWSGLTIATLGTIASVVSQPGLTQVLQPTTTPGAIALPDYGLWQNQERQKLLNAIDHSLRYIDTNTAQADYAAVQVP
GFSREKVRRSLVRFRQLVQQYPDPRQLHQAIQREFIFYRSVGKDGTGQVDFTAYFEPAYVASPVKTNEFQYPLYRQPPGF
KTWSQPHPRRVALEGRDGIPPSDSPLRGHELVWLKSRLEAYLIQVQGSARLQLTNGRTMTIGFDGSTDYEYVSLGKELIN
EGIFQPEELSLPKLIDYFEANPTELSNYIPRNNRFIFFRETFGSPPIGSIGVPVLAERSIATDKSIFPPGAIAFIATQLP
YQRANGDWLKLPVSRYVLDQDTGSAIKGAGRVDIFLGTGPNTQTRAGLVNDPGNLYYLLLKD

Sequences:

>Translated_382_residues
MKIFWSGLTIATLGTIASVVSQPGLTQVLQPTTTPGAIALPDYGLWQNQERQKLLNAIDHSLRYIDTNTAQADYAAVQVP
GFSREKVRRSLVRFRQLVQQYPDPRQLHQAIQREFIFYRSVGKDGTGQVDFTAYFEPAYVASPVKTNEFQYPLYRQPPGF
KTWSQPHPRRVALEGRDGIPPSDSPLRGHELVWLKSRLEAYLIQVQGSARLQLTNGRTMTIGFDGSTDYEYVSLGKELIN
EGIFQPEELSLPKLIDYFEANPTELSNYIPRNNRFIFFRETFGSPPIGSIGVPVLAERSIATDKSIFPPGAIAFIATQLP
YQRANGDWLKLPVSRYVLDQDTGSAIKGAGRVDIFLGTGPNTQTRAGLVNDPGNLYYLLLKD
>Mature_382_residues
MKIFWSGLTIATLGTIASVVSQPGLTQVLQPTTTPGAIALPDYGLWQNQERQKLLNAIDHSLRYIDTNTAQADYAAVQVP
GFSREKVRRSLVRFRQLVQQYPDPRQLHQAIQREFIFYRSVGKDGTGQVDFTAYFEPAYVASPVKTNEFQYPLYRQPPGF
KTWSQPHPRRVALEGRDGIPPSDSPLRGHELVWLKSRLEAYLIQVQGSARLQLTNGRTMTIGFDGSTDYEYVSLGKELIN
EGIFQPEELSLPKLIDYFEANPTELSNYIPRNNRFIFFRETFGSPPIGSIGVPVLAERSIATDKSIFPPGAIAFIATQLP
YQRANGDWLKLPVSRYVLDQDTGSAIKGAGRVDIFLGTGPNTQTRAGLVNDPGNLYYLLLKD

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG2821

COG function: function code M; Membrane-bound lytic murein transglycosylase

Gene ontology:

Cell location: Note=In closely related bacteria this protein is attached to the outer membrane by a lipid anchor. This is apparently not the case here [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789179, Length=259, Percent_Identity=30.1158301158301, Blast_Score=114, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010611
- InterPro:   IPR014733
- InterPro:   IPR005300 [H]

Pfam domain/function: PF06725 3D; PF03562 MltA [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 42789; Mature: 42789

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIFWSGLTIATLGTIASVVSQPGLTQVLQPTTTPGAIALPDYGLWQNQERQKLLNAIDH
CEEEECCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHH
SLRYIDTNTAQADYAAVQVPGFSREKVRRSLVRFRQLVQQYPDPRQLHQAIQREFIFYRS
HHEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VGKDGTGQVDFTAYFEPAYVASPVKTNEFQYPLYRQPPGFKTWSQPHPRRVALEGRDGIP
CCCCCCCCEEEEEEECCHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCC
PSDSPLRGHELVWLKSRLEAYLIQVQGSARLQLTNGRTMTIGFDGSTDYEYVSLGKELIN
CCCCCCCCCEEEEEHHCCEEEEEEECCCEEEEEECCEEEEEEECCCCCHHHHHHHHHHHH
EGIFQPEELSLPKLIDYFEANPTELSNYIPRNNRFIFFRETFGSPPIGSIGVPVLAERSI
HCCCCCHHCCHHHHHHHHCCCHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCEECCCC
ATDKSIFPPGAIAFIATQLPYQRANGDWLKLPVSRYVLDQDTGSAIKGAGRVDIFLGTGP
CCCCCCCCCCHHEEEEHHCCCCCCCCCEEEECHHHEEEECCCCCHHCCCCEEEEEEECCC
NTQTRAGLVNDPGNLYYLLLKD
CCCCCCCEECCCCCEEEEEEEC
>Mature Secondary Structure
MKIFWSGLTIATLGTIASVVSQPGLTQVLQPTTTPGAIALPDYGLWQNQERQKLLNAIDH
CEEEECCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHH
SLRYIDTNTAQADYAAVQVPGFSREKVRRSLVRFRQLVQQYPDPRQLHQAIQREFIFYRS
HHEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VGKDGTGQVDFTAYFEPAYVASPVKTNEFQYPLYRQPPGFKTWSQPHPRRVALEGRDGIP
CCCCCCCCEEEEEEECCHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCC
PSDSPLRGHELVWLKSRLEAYLIQVQGSARLQLTNGRTMTIGFDGSTDYEYVSLGKELIN
CCCCCCCCCEEEEEHHCCEEEEEEECCCEEEEEECCEEEEEEECCCCCHHHHHHHHHHHH
EGIFQPEELSLPKLIDYFEANPTELSNYIPRNNRFIFFRETFGSPPIGSIGVPVLAERSI
HCCCCCHHCCHHHHHHHHCCCHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCEECCCC
ATDKSIFPPGAIAFIATQLPYQRANGDWLKLPVSRYVLDQDTGSAIKGAGRVDIFLGTGP
CCCCCCCCCCHHEEEEHHCCCCCCCCCEEEECHHHEEEECCCCCHHCCCCEEEEEEECCC
NTQTRAGLVNDPGNLYYLLLKD
CCCCCCCEECCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic [C]

General reaction: Cleavage Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]