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The map label for this gene is trx [C]

Identifier: 170078963

GI number: 170078963

Start: 2450076

End: 2450399

Strand: Direct

Name: trx [C]

Synonym: SYNPCC7002_A2368

Alternate gene names: 170078963

Gene position: 2450076-2450399 (Clockwise)

Preceding gene: 170078961

Following gene: 170078964

Centisome position: 81.45

GC content: 49.69

Gene sequence:

>324_bases
ATGGCTGTCAAAAAACAATTTTCCAGTTTTGAAGCAATGTTACAGGCTGCCGAAAAGCCTGTTTTAGTCGATTTTTATGC
AACTTGGTGTGGCCCCTGCCAAATTATGGGCAAAACCCTCGAAGAAATCAGCCCCCAAATGGCCAATGAAATTCAAATCG
TCAAAGTAGACGGCGATCGCTATCCGGCCCTTGCCTCCCACCACGGTGTCCATGCCTATCCCACCCTCGTGCTCTACAAC
AAAGGACAATTAGTTTCCCGCATCGAAGGGGCCGTTGCCGCGCCACAACTGATGCAACAAATCCGCCGCGCCCTCCAAAA
TTAA

Upstream 100 bases:

>100_bases
CTCCAAAAGTCTTTGCGTTTTGATGACTGGGTTATCATAGGAGTTAGGGTCGTGCGATCGCAACAATTCCCCTCGCAATC
TCGTTTCGGAGCTATTTTCC

Downstream 100 bases:

>100_bases
GCCTTCAACATCACTCCCCTGGTGGCGAGCTTAACGGTTACTGCTCAAAATATTCAATCTAAATCCCAGGGAATATTTAC
ATTTCTTGACCCGGCCGGGT

Product: thioredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 107; Mature: 106

Protein sequence:

>107_residues
MAVKKQFSSFEAMLQAAEKPVLVDFYATWCGPCQIMGKTLEEISPQMANEIQIVKVDGDRYPALASHHGVHAYPTLVLYN
KGQLVSRIEGAVAAPQLMQQIRRALQN

Sequences:

>Translated_107_residues
MAVKKQFSSFEAMLQAAEKPVLVDFYATWCGPCQIMGKTLEEISPQMANEIQIVKVDGDRYPALASHHGVHAYPTLVLYN
KGQLVSRIEGAVAAPQLMQQIRRALQN
>Mature_106_residues
AVKKQFSSFEAMLQAAEKPVLVDFYATWCGPCQIMGKTLEEISPQMANEIQIVKVDGDRYPALASHHGVHAYPTLVLYNK
GQLVSRIEGAVAAPQLMQQIRRALQN

Specific function: Participates In Various Redox Reactions Through The Reversible Oxidation Of Its Active Center Dithiol To A Disulfide And Catalyzes Dithiol-Disulfide Exchange Reactions. [C]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI21361403, Length=89, Percent_Identity=35.9550561797753, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87082331, Length=92, Percent_Identity=32.6086956521739, Blast_Score=75, Evalue=1e-15,
Organism=Escherichia coli, GI1788936, Length=73, Percent_Identity=34.2465753424658, Blast_Score=68, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI212646193, Length=86, Percent_Identity=36.046511627907, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321648, Length=87, Percent_Identity=35.632183908046, Blast_Score=69, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319925, Length=86, Percent_Identity=38.3720930232558, Blast_Score=67, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323072, Length=87, Percent_Identity=39.0804597701149, Blast_Score=67, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17648013, Length=81, Percent_Identity=37.037037037037, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24583090, Length=81, Percent_Identity=37.037037037037, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28573567, Length=97, Percent_Identity=29.8969072164948, Blast_Score=69, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17530795, Length=92, Percent_Identity=29.3478260869565, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639826, Length=78, Percent_Identity=32.0512820512821, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 11887; Mature: 11756

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKKQFSSFEAMLQAAEKPVLVDFYATWCGPCQIMGKTLEEISPQMANEIQIVKVDGDR
CCCHHHHHHHHHHHHHCCCCEEEEHHHHHCCHHHHHHHHHHHCCHHHHCCEEEEEECCCC
YPALASHHGVHAYPTLVLYNKGQLVSRIEGAVAAPQLMQQIRRALQN
CCCHHCCCCCCCCCEEEEECCCHHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AVKKQFSSFEAMLQAAEKPVLVDFYATWCGPCQIMGKTLEEISPQMANEIQIVKVDGDR
CCHHHHHHHHHHHHHCCCCEEEEHHHHHCCHHHHHHHHHHHCCHHHHCCEEEEEECCCC
YPALASHHGVHAYPTLVLYNKGQLVSRIEGAVAAPQLMQQIRRALQN
CCCHHCCCCCCCCCEEEEECCCHHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]