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The map label for this gene is hisS

Identifier: 170078871

GI number: 170078871

Start: 2358477

End: 2359757

Strand: Reverse

Name: hisS

Synonym: SYNPCC7002_A2275

Alternate gene names: 170078871

Gene position: 2359757-2358477 (Counterclockwise)

Preceding gene: 170078872

Following gene: 170078870

Centisome position: 78.45

GC content: 55.19

Gene sequence:

>1281_bases
ATGGCAACAATTCAAGCTTTACGAGGAACAAAGGATATTTTTGCGCCGGAGATCGCCTACTGGCAGCAGGTAGAGGCGGT
GGTGCGCGATTGCCTCGGCCGGGCGATGTACCAGGAGATCCGCACGCCCATTTTTGAGCAGACCAGCCTGTTTGAGCGGG
GGATCGGTGAGGCGACGGACGTGGTCAGTAAGGAAATGTATTCTTTCACAGACCGGGGCGATCGCCCGATTACCCTCCGG
CCTGAAGGGACAGCAGGGGCAGTCCGGGCCTATATTGAGCGGAAATTGTTTGCCCAAGGTGGTGTGCAGCGGCTGTGGTA
CACAGGGCCAATGTTTCGCTATGAAAGACCCCAAGCGGGCCGTCAACGGCAATTTCACCAGGTGGGGGTCGAGGTGCTTG
GCAGTGCGGATCCCCGCGCCGATGTGGAAGTGATGGCGATCGCCACGGAAATTTTGCAGAAACTCGGCCTGAAAAATCTC
AGCCTGCAATTAAACTCGGTGGGGAATGGCGGCGATCGCCAACGGTATCGTGAAGCTTTAGTAGACTATCTAACCCCTTT
TAAGGCGGATTTAGACGCAGATTCCCAGGAGCGGCTCGAGCGCAATCCCCTGCGCATCTTGGATAGCAAAGATCAAAAAA
CCCAAGAAATTGCCCAAAATGCCCCCAGTATCCTGGATTATCTGGGGGATGACTCAAAAAAACATTTCGACCAAGTACAA
AGCTCCCTCACGGCCCTGGGCATTGATTATGTGTTAAACCCTTGCCTCGTGAGGGGCCTAGACTACTACACCCACACCGC
CTTTGAAATCCAATCCAGCGACCTCGGTGCCCAGGCAACGGTCTGTGGGGGCGGACGTTACGACGGCCTCGTGGCAGAAT
TGGGTGGCCCCGAAACACCAGCAGTGGGTTGGGCCATTGGTTTGGAGCGTTTGGTGATCCTGTTACAACAATTGGGAGAA
GCCTCCGGCCCCCAACTAGATTTTTACCTCGTTTCCAAAGGAGAACAGGCCGAGGCCGCCGCTGTGATTTTGGCCCATAA
GTTGCGTTTTGCGGGGTTCTCAGTGGAGCTTGATCTCAGTGGCAGTGCCTTTGGGAAGCAATTTAAACGGGCTGACCGCA
GTGGGGCGATCGCCTGTTTGGTGCTCGGCGATGAAGAAGCCGTCAACCAGCAGGTACAACTCAAGTGGCTCCAGACCAAG
GCCCAAGAAACCCTGGCCCAAGCGGATCTGCTGGGAAATCTTGAGTCATGGCGTCAAAAAATGCAGCAGGCAAAACATTA
G

Upstream 100 bases:

>100_bases
TGACAGCATTTGGGGCAGGATACATGGTAGTTTTACCTCTGCTGAACAATAACAACGCCCCATCCCGATAAGCTGGGATT
GGTACTTTTTTCTAGACATA

Downstream 100 bases:

>100_bases
AACCCCAGAGGAGGCGTCGATGGTGCACTGGCAATTTCTGCTACAAAAAAAAGGCGATCGCAATTGGGACATCCTCCAGA
CCGAGACCCTGAGCTTAGCG

Product: histidyl-tRNA synthetase

Products: NA

Alternate protein names: Histidine--tRNA ligase; HisRS

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MATIQALRGTKDIFAPEIAYWQQVEAVVRDCLGRAMYQEIRTPIFEQTSLFERGIGEATDVVSKEMYSFTDRGDRPITLR
PEGTAGAVRAYIERKLFAQGGVQRLWYTGPMFRYERPQAGRQRQFHQVGVEVLGSADPRADVEVMAIATEILQKLGLKNL
SLQLNSVGNGGDRQRYREALVDYLTPFKADLDADSQERLERNPLRILDSKDQKTQEIAQNAPSILDYLGDDSKKHFDQVQ
SSLTALGIDYVLNPCLVRGLDYYTHTAFEIQSSDLGAQATVCGGGRYDGLVAELGGPETPAVGWAIGLERLVILLQQLGE
ASGPQLDFYLVSKGEQAEAAAVILAHKLRFAGFSVELDLSGSAFGKQFKRADRSGAIACLVLGDEEAVNQQVQLKWLQTK
AQETLAQADLLGNLESWRQKMQQAKH

Sequences:

>Translated_426_residues
MATIQALRGTKDIFAPEIAYWQQVEAVVRDCLGRAMYQEIRTPIFEQTSLFERGIGEATDVVSKEMYSFTDRGDRPITLR
PEGTAGAVRAYIERKLFAQGGVQRLWYTGPMFRYERPQAGRQRQFHQVGVEVLGSADPRADVEVMAIATEILQKLGLKNL
SLQLNSVGNGGDRQRYREALVDYLTPFKADLDADSQERLERNPLRILDSKDQKTQEIAQNAPSILDYLGDDSKKHFDQVQ
SSLTALGIDYVLNPCLVRGLDYYTHTAFEIQSSDLGAQATVCGGGRYDGLVAELGGPETPAVGWAIGLERLVILLQQLGE
ASGPQLDFYLVSKGEQAEAAAVILAHKLRFAGFSVELDLSGSAFGKQFKRADRSGAIACLVLGDEEAVNQQVQLKWLQTK
AQETLAQADLLGNLESWRQKMQQAKH
>Mature_425_residues
ATIQALRGTKDIFAPEIAYWQQVEAVVRDCLGRAMYQEIRTPIFEQTSLFERGIGEATDVVSKEMYSFTDRGDRPITLRP
EGTAGAVRAYIERKLFAQGGVQRLWYTGPMFRYERPQAGRQRQFHQVGVEVLGSADPRADVEVMAIATEILQKLGLKNLS
LQLNSVGNGGDRQRYREALVDYLTPFKADLDADSQERLERNPLRILDSKDQKTQEIAQNAPSILDYLGDDSKKHFDQVQS
SLTALGIDYVLNPCLVRGLDYYTHTAFEIQSSDLGAQATVCGGGRYDGLVAELGGPETPAVGWAIGLERLVILLQQLGEA
SGPQLDFYLVSKGEQAEAAAVILAHKLRFAGFSVELDLSGSAFGKQFKRADRSGAIACLVLGDEEAVNQQVQLKWLQTKA
QETLAQADLLGNLESWRQKMQQAKH

Specific function: Unknown

COG id: COG0124

COG function: function code J; Histidyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI6996014, Length=466, Percent_Identity=24.0343347639485, Blast_Score=92, Evalue=7e-19,
Organism=Escherichia coli, GI1788861, Length=419, Percent_Identity=47.4940334128878, Blast_Score=377, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYH_SYNP2 (B1XJ88)

Other databases:

- EMBL:   CP000951
- RefSeq:   YP_001735509.1
- ProteinModelPortal:   B1XJ88
- SMR:   B1XJ88
- GeneID:   6055406
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A2275
- HOGENOM:   HBG616575
- OMA:   VFEWVTT
- ProtClustDB:   PRK00037
- GO:   GO:0005737
- HAMAP:   MF_00127
- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR015807
- InterPro:   IPR004516
- Gene3D:   G3DSA:3.40.50.800
- PANTHER:   PTHR11476
- PIRSF:   PIRSF001549
- TIGRFAMs:   TIGR00442

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b; SSF52954 Anticodon_bd

EC number: =6.1.1.21

Molecular weight: Translated: 47204; Mature: 47073

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIQALRGTKDIFAPEIAYWQQVEAVVRDCLGRAMYQEIRTPIFEQTSLFERGIGEATD
CCCHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHH
VVSKEMYSFTDRGDRPITLRPEGTAGAVRAYIERKLFAQGGVQRLWYTGPMFRYERPQAG
HHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCEECCCCCH
RQRQFHQVGVEVLGSADPRADVEVMAIATEILQKLGLKNLSLQLNSVGNGGDRQRYREAL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHH
VDYLTPFKADLDADSQERLERNPLRILDSKDQKTQEIAQNAPSILDYLGDDSKKHFDQVQ
HHHHCCCCCCCCCCHHHHHHCCCCEEECCCCHHHHHHHHCCHHHHHHHCCCHHHHHHHHH
SSLTALGIDYVLNPCLVRGLDYYTHTAFEIQSSDLGAQATVCGGGRYDGLVAELGGPETP
HHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCEEEEECCCCCCCCCEECCCCCCC
AVGWAIGLERLVILLQQLGEASGPQLDFYLVSKGEQAEAAAVILAHKLRFAGFSVELDLS
CHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEECC
GSAFGKQFKRADRSGAIACLVLGDEEAVNQQVQLKWLQTKAQETLAQADLLGNLESWRQK
CCHHHHHHHHCCCCCCEEEEEECCHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
MQQAKH
HHHHCC
>Mature Secondary Structure 
ATIQALRGTKDIFAPEIAYWQQVEAVVRDCLGRAMYQEIRTPIFEQTSLFERGIGEATD
CCHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHH
VVSKEMYSFTDRGDRPITLRPEGTAGAVRAYIERKLFAQGGVQRLWYTGPMFRYERPQAG
HHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCEECCCCCH
RQRQFHQVGVEVLGSADPRADVEVMAIATEILQKLGLKNLSLQLNSVGNGGDRQRYREAL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHH
VDYLTPFKADLDADSQERLERNPLRILDSKDQKTQEIAQNAPSILDYLGDDSKKHFDQVQ
HHHHCCCCCCCCCCHHHHHHCCCCEEECCCCHHHHHHHHCCHHHHHHHCCCHHHHHHHHH
SSLTALGIDYVLNPCLVRGLDYYTHTAFEIQSSDLGAQATVCGGGRYDGLVAELGGPETP
HHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCEEEEECCCCCCCCCEECCCCCCC
AVGWAIGLERLVILLQQLGEASGPQLDFYLVSKGEQAEAAAVILAHKLRFAGFSVELDLS
CHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEECC
GSAFGKQFKRADRSGAIACLVLGDEEAVNQQVQLKWLQTKAQETLAQADLLGNLESWRQK
CCHHHHHHHHCCCCCCEEEEEECCHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
MQQAKH
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA