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The map label for this gene is lon2 [H]

Identifier: 170078663

GI number: 170078663

Start: 2143289

End: 2143927

Strand: Reverse

Name: lon2 [H]

Synonym: SYNPCC7002_A2059

Alternate gene names: 170078663

Gene position: 2143927-2143289 (Counterclockwise)

Preceding gene: 170078664

Following gene: 170078662

Centisome position: 71.27

GC content: 47.73

Gene sequence:

>639_bases
ATGACCTCTTTTTCCGTTGCTGTCCGAGAACTACCACTTTTCCCGTTACCGGAATTGGTGCTGTTTCCATCGCGGCCTTT
ACCGCTCCATGTGTTTGAGTTTCGGTACCGCATTATGATGAACACGATTTTGGAGCATGATCGACGTTTTGGGGTATTAA
TGGTCAATCCTGTGGATGGCACGATCGCCAATGTGGGTTGTTGCGCAGAAATTGTCCACTGCGAAAAATTACCCGATGGC
CGAATGAAAATGTTGACGATTGGCCAACAGCGATTTCGGGTTTTAGATTATGTCCGTGAAAAGCCCTACCGGGTCGGTTT
GGTGGAATGGATCGAAGATGATCCAACGACAGGAAATTTATCTTCTTTGGCGGTAGATGCAAAACAGGTGTTAATGGATG
TGGTGGGTTTATCGGCCAAGCTCGCCGGTCAAGATCTAGAGCTACCGGAGGAATTGCCGGATCTGCCACGGGAATTGTCT
TTTTGGATTGCGGGTAGTTTGTATGGCGTTGCGGAGGAGCAACAAGCCCTCTTGGAATTACAAGACACCCAGGAAAGATT
GCGGCGGGAGGTAGAAATTTTGACTTCTACGAGAAATCATTTGGCGGCCAGAACAGCGTTGAAAGATGTGTTTGAATAA

Upstream 100 bases:

>100_bases
TCTGGGTCTTTTCTGAATTTATTTCGGGGAAGACCCTTTCCGTTTCCTTTAGGTTTTGTATATCCGCTACAGTATAAACA
GATCGTATTTGTCACCGCCC

Downstream 100 bases:

>100_bases
CTGAGATTGTCCCTAGATAGTCATGGAAAAGTTGTATTAAAGCGATGGTGGACTGGTCACAGACGGATTTGGAAGGGGCG
ATCGCCAACTTTTCAGAGAT

Product: putative ATP-dependent proteinase

Products: NA

Alternate protein names: ATP-dependent protease La 2 [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MTSFSVAVRELPLFPLPELVLFPSRPLPLHVFEFRYRIMMNTILEHDRRFGVLMVNPVDGTIANVGCCAEIVHCEKLPDG
RMKMLTIGQQRFRVLDYVREKPYRVGLVEWIEDDPTTGNLSSLAVDAKQVLMDVVGLSAKLAGQDLELPEELPDLPRELS
FWIAGSLYGVAEEQQALLELQDTQERLRREVEILTSTRNHLAARTALKDVFE

Sequences:

>Translated_212_residues
MTSFSVAVRELPLFPLPELVLFPSRPLPLHVFEFRYRIMMNTILEHDRRFGVLMVNPVDGTIANVGCCAEIVHCEKLPDG
RMKMLTIGQQRFRVLDYVREKPYRVGLVEWIEDDPTTGNLSSLAVDAKQVLMDVVGLSAKLAGQDLELPEELPDLPRELS
FWIAGSLYGVAEEQQALLELQDTQERLRREVEILTSTRNHLAARTALKDVFE
>Mature_211_residues
TSFSVAVRELPLFPLPELVLFPSRPLPLHVFEFRYRIMMNTILEHDRRFGVLMVNPVDGTIANVGCCAEIVHCEKLPDGR
MKMLTIGQQRFRVLDYVREKPYRVGLVEWIEDDPTTGNLSSLAVDAKQVLMDVVGLSAKLAGQDLELPEELPDLPRELSF
WIAGSLYGVAEEQQALLELQDTQERLRREVEILTSTRNHLAARTALKDVFE

Specific function: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced

COG id: COG2802

COG function: function code R; Uncharacterized protein, similar to the N-terminal domain of Lon protease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Lon domain [H]

Homologues:

Organism=Homo sapiens, GI148528975, Length=218, Percent_Identity=30.7339449541284, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI73747840, Length=119, Percent_Identity=35.2941176470588, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI37622896, Length=119, Percent_Identity=35.2941176470588, Blast_Score=74, Evalue=7e-14,
Organism=Homo sapiens, GI87080813, Length=107, Percent_Identity=35.5140186915888, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008269
- InterPro:   IPR004815
- InterPro:   IPR003111
- InterPro:   IPR008268
- InterPro:   IPR001984
- InterPro:   IPR015947
- InterPro:   IPR020568 [H]

Pfam domain/function: PF00004 AAA; PF02190 LON; PF05362 Lon_C [H]

EC number: =3.4.21.53 [H]

Molecular weight: Translated: 24132; Mature: 24001

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSFSVAVRELPLFPLPELVLFPSRPLPLHVFEFRYRIMMNTILEHDRRFGVLMVNPVDG
CCCHHHHHHHCCCCCCCHHEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
TIANVGCCAEIVHCEKLPDGRMKMLTIGQQRFRVLDYVREKPYRVGLVEWIEDDPTTGNL
CHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCEECHHHHHCCCCCCCCH
SSLAVDAKQVLMDVVGLSAKLAGQDLELPEELPDLPRELSFWIAGSLYGVAEEQQALLEL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHH
QDTQERLRREVEILTSTRNHLAARTALKDVFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSFSVAVRELPLFPLPELVLFPSRPLPLHVFEFRYRIMMNTILEHDRRFGVLMVNPVDG
CCHHHHHHHCCCCCCCHHEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
TIANVGCCAEIVHCEKLPDGRMKMLTIGQQRFRVLDYVREKPYRVGLVEWIEDDPTTGNL
CHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCEECHHHHHCCCCCCCCH
SSLAVDAKQVLMDVVGLSAKLAGQDLELPEELPDLPRELSFWIAGSLYGVAEEQQALLEL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHH
QDTQERLRREVEILTSTRNHLAARTALKDVFE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8331083; 8331082 [H]