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The map label for this gene is crp [H]

Identifier: 170078395

GI number: 170078395

Start: 1875912

End: 1876622

Strand: Direct

Name: crp [H]

Synonym: SYNPCC7002_A1789

Alternate gene names: 170078395

Gene position: 1875912-1876622 (Clockwise)

Preceding gene: 170078394

Following gene: 170078396

Centisome position: 62.36

GC content: 53.87

Gene sequence:

>711_bases
ATGGCCGAATCCCCCACGAATCCGGTGAGTGATGACACAGCCCGCACCTTCCTCAAGGCGTTGCCTTTTTTCCAGGGGCT
ACCGGAGGCAAGTCTACAAAAGGCGATCTCCCATCTGGTGACGCGGCCCTTCCCAGCCAACCAAATTATCCTTTTAGAAA
AAGACTGGGGCGGTTCTGTTTACTTTATCCAGACGGGCTGGGTGAAAATTCGCACCTACAACCTCGATGGCAAAGAAATT
ACCCTGAATATCCTCGGCGCTGGGGAATTATTTGGCGAAATGGCCGCCCTCGAAGAAGCCACCCGTTCCACCGATGTGAT
CACCCTGACCGCCACCACCATTAGTAGTATCCCCGCCGCCGACTTCGTTGAATTGGTAAACACAGAGCCTCTGGTGGGAG
TCCGTCTCGCCCAACTGATGGCCAAACGCCTCCGCCAAGTGAACCGTCGCCTCCAGGTGCGCGAAACCAATAGTCTGGCG
CGAGTCGCTGATATCTTGGTCTTTTTAGCTGAAAGTCAAGGACAAGCCACAGACCAAGGGGAGATCCGCATTCCGAGTCT
GCCCCATCGAGAACTGAGTAGTTTAAGTGGTCTGGCGCGGGAGACAGTCACGCGGGTTTTGACTAAGTTAGAAAAGAAAG
GTTTAATTAGGCGCACCCCGGATGCTGTGTTTATCCCAAATCTGCGTGCCCTCGACGACATCATCCATTAG

Upstream 100 bases:

>100_bases
ATTGCATAATGGAGGGAGATTTAAGCTCAGTGTGGCCCTGCCATTCGACAGATCTATCGCTATCAGCAGTTAGTATCTCC
TGCCCTTTGCCCCAAGAATT

Downstream 100 bases:

>100_bases
GCGATCGCTGTGACTGAGCATTTTTCTGATCCAAAGAATTCTCCAGAAGATATGAATTGGGTAGATTTAGATTCCCAAGC
ATCCCAACCCCCAAGCTCCT

Product: transcriptional regulator

Products: NA

Alternate protein names: cAMP receptor protein; cAMP regulatory protein [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MAESPTNPVSDDTARTFLKALPFFQGLPEASLQKAISHLVTRPFPANQIILLEKDWGGSVYFIQTGWVKIRTYNLDGKEI
TLNILGAGELFGEMAALEEATRSTDVITLTATTISSIPAADFVELVNTEPLVGVRLAQLMAKRLRQVNRRLQVRETNSLA
RVADILVFLAESQGQATDQGEIRIPSLPHRELSSLSGLARETVTRVLTKLEKKGLIRRTPDAVFIPNLRALDDIIH

Sequences:

>Translated_236_residues
MAESPTNPVSDDTARTFLKALPFFQGLPEASLQKAISHLVTRPFPANQIILLEKDWGGSVYFIQTGWVKIRTYNLDGKEI
TLNILGAGELFGEMAALEEATRSTDVITLTATTISSIPAADFVELVNTEPLVGVRLAQLMAKRLRQVNRRLQVRETNSLA
RVADILVFLAESQGQATDQGEIRIPSLPHRELSSLSGLARETVTRVLTKLEKKGLIRRTPDAVFIPNLRALDDIIH
>Mature_235_residues
AESPTNPVSDDTARTFLKALPFFQGLPEASLQKAISHLVTRPFPANQIILLEKDWGGSVYFIQTGWVKIRTYNLDGKEIT
LNILGAGELFGEMAALEEATRSTDVITLTATTISSIPAADFVELVNTEPLVGVRLAQLMAKRLRQVNRRLQVRETNSLAR
VADILVFLAESQGQATDQGEIRIPSLPHRELSSLSGLARETVTRVLTKLEKKGLIRRTPDAVFIPNLRALDDIIH

Specific function: This protein complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of one or more genes involved in the induction of competence [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789756, Length=201, Percent_Identity=26.3681592039801, Blast_Score=77, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR018488
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 26067; Mature: 25936

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAESPTNPVSDDTARTFLKALPFFQGLPEASLQKAISHLVTRPFPANQIILLEKDWGGSV
CCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEE
YFIQTGWVKIRTYNLDGKEITLNILGAGELFGEMAALEEATRSTDVITLTATTISSIPAA
EEEEECEEEEEEEECCCCEEEEEEEECHHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCHH
DFVELVNTEPLVGVRLAQLMAKRLRQVNRRLQVRETNSLARVADILVFLAESQGQATDQG
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHCCCCCCCCCC
EIRIPSLPHRELSSLSGLARETVTRVLTKLEKKGLIRRTPDAVFIPNLRALDDIIH
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEECCCHHHHHHHCC
>Mature Secondary Structure 
AESPTNPVSDDTARTFLKALPFFQGLPEASLQKAISHLVTRPFPANQIILLEKDWGGSV
CCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEE
YFIQTGWVKIRTYNLDGKEITLNILGAGELFGEMAALEEATRSTDVITLTATTISSIPAA
EEEEECEEEEEEEECCCCEEEEEEEECHHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCHH
DFVELVNTEPLVGVRLAQLMAKRLRQVNRRLQVRETNSLARVADILVFLAESQGQATDQG
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHCCCCCCCCCC
EIRIPSLPHRELSSLSGLARETVTRVLTKLEKKGLIRRTPDAVFIPNLRALDDIIH
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCEEECCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1542653; 7542800 [H]