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The map label for this gene is galE [H]

Identifier: 170078322

GI number: 170078322

Start: 1801959

End: 1802951

Strand: Reverse

Name: galE [H]

Synonym: SYNPCC7002_A1715

Alternate gene names: 170078322

Gene position: 1802951-1801959 (Counterclockwise)

Preceding gene: 170078323

Following gene: 170078321

Centisome position: 59.94

GC content: 53.17

Gene sequence:

>993_bases
ATGGCAGACAAAACAGTTTTAGTCACGGGGGGAGCGGGTTACATTGGCTCCCAGGCGGTATTGAGTCTGCAACGGCGCGG
TTATCGGGTCATTGTGCTAGATAACTTGGTCTATGGTCACCAAGATTTAGTGGCGTCGGTGCTCAAAGCGGAACTGATCG
TTGGGGACACAGGCGATCGCCCTTTGTTAGATCAAATTTTTGCAGACCACAAAATCGATGCGGTGATGCACTTTGCCGCC
TATGCCTATGTGGGGGAATCGGTCACGGCACCGGGCAAATATTACCGGAATAACGTGGTGGGTACGTTGACCCTCCTGGA
GGCGATGGTTGCGGCCGGGGTAAAACAATTCGTCTTTTCTTCTACCTGTGCCACCTACGGCGAACCAAGCGAAATTCCCA
TCCCCGAAGCTCATCCCCAAAACCCGATTAACCCCTACGGCATGAGCAAGCTGATGGTGGAAAAAATGCTCTGGGATTTT
GACCGGGCCTATGGGTTGCGGTCGGTGATGTTTCGTTATTTCAACGCAGCGGGAGCTGATCCCAATGGTCACCTAGGAGA
AGACCACAACCCCGAAACCCACTTGATCCCCCTGGTACTCTTTGCAGCCCTTGGTAAACGAGACAGTATTTCCATTTTTG
GCACCAATTATCCTACCCCCGACGGTACTTGCGTCCGGGATTATATCCATGTGAGTGACCTCGCCGACGCCCATGTTTTA
GGTCTGGAATATTTACGGCAAGGCGGGGTAACTGAGGCCTTTAACCTCGGCAATGGCAATGGGTTTTCGGTAAAGGAGGT
AATTGAGGCCGCCCGCAAAATTACCGCCAAAGAGATCAAGGCGATCGCCACCGACCGTCGCCCCGGTGATCCCCCCAGCC
TTGTGGGGAGCAGTGAAAAAGCCCGTACAGTTCTGGGTTGGCAACCCCAATACGCCGACCTAGAAACTATTTTGCAACAC
GCTTGGCACTGGCACCAACAGCGTCATGGTTAA

Upstream 100 bases:

>100_bases
CTAAATTCTAGTTTCTGAATTTGAGAAAGGATTTGATGCCGAACCAGTTAATTGCACGAATGTTCTAGCGGTCATTTAGA
AGATAAACAGGGGGACAGCC

Downstream 100 bases:

>100_bases
CCTAGCAGTCAGGAAAATTGGCGATCGCCCAGCAGAAACTCCCGAATTCTGAAAGAGAAAGGAACTCAACCAGATAAAAT
AAAAAGCCACTACCCCGCTT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MADKTVLVTGGAGYIGSQAVLSLQRRGYRVIVLDNLVYGHQDLVASVLKAELIVGDTGDRPLLDQIFADHKIDAVMHFAA
YAYVGESVTAPGKYYRNNVVGTLTLLEAMVAAGVKQFVFSSTCATYGEPSEIPIPEAHPQNPINPYGMSKLMVEKMLWDF
DRAYGLRSVMFRYFNAAGADPNGHLGEDHNPETHLIPLVLFAALGKRDSISIFGTNYPTPDGTCVRDYIHVSDLADAHVL
GLEYLRQGGVTEAFNLGNGNGFSVKEVIEAARKITAKEIKAIATDRRPGDPPSLVGSSEKARTVLGWQPQYADLETILQH
AWHWHQQRHG

Sequences:

>Translated_330_residues
MADKTVLVTGGAGYIGSQAVLSLQRRGYRVIVLDNLVYGHQDLVASVLKAELIVGDTGDRPLLDQIFADHKIDAVMHFAA
YAYVGESVTAPGKYYRNNVVGTLTLLEAMVAAGVKQFVFSSTCATYGEPSEIPIPEAHPQNPINPYGMSKLMVEKMLWDF
DRAYGLRSVMFRYFNAAGADPNGHLGEDHNPETHLIPLVLFAALGKRDSISIFGTNYPTPDGTCVRDYIHVSDLADAHVL
GLEYLRQGGVTEAFNLGNGNGFSVKEVIEAARKITAKEIKAIATDRRPGDPPSLVGSSEKARTVLGWQPQYADLETILQH
AWHWHQQRHG
>Mature_329_residues
ADKTVLVTGGAGYIGSQAVLSLQRRGYRVIVLDNLVYGHQDLVASVLKAELIVGDTGDRPLLDQIFADHKIDAVMHFAAY
AYVGESVTAPGKYYRNNVVGTLTLLEAMVAAGVKQFVFSSTCATYGEPSEIPIPEAHPQNPINPYGMSKLMVEKMLWDFD
RAYGLRSVMFRYFNAAGADPNGHLGEDHNPETHLIPLVLFAALGKRDSISIFGTNYPTPDGTCVRDYIHVSDLADAHVLG
LEYLRQGGVTEAFNLGNGNGFSVKEVIEAARKITAKEIKAIATDRRPGDPPSLVGSSEKARTVLGWQPQYADLETILQHA
WHWHQQRHG

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=341, Percent_Identity=40.4692082111437, Blast_Score=238, Evalue=7e-63,
Organism=Homo sapiens, GI56118217, Length=341, Percent_Identity=40.4692082111437, Blast_Score=238, Evalue=7e-63,
Organism=Homo sapiens, GI189083684, Length=341, Percent_Identity=40.4692082111437, Blast_Score=238, Evalue=7e-63,
Organism=Homo sapiens, GI7657641, Length=320, Percent_Identity=28.75, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI42516563, Length=340, Percent_Identity=27.0588235294118, Blast_Score=95, Evalue=9e-20,
Organism=Escherichia coli, GI1786974, Length=332, Percent_Identity=43.9759036144578, Blast_Score=257, Evalue=6e-70,
Organism=Escherichia coli, GI1788353, Length=339, Percent_Identity=31.5634218289086, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI48994969, Length=351, Percent_Identity=28.4900284900285, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1790049, Length=273, Percent_Identity=30.03663003663, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788366, Length=357, Percent_Identity=24.0896358543417, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71982035, Length=340, Percent_Identity=37.6470588235294, Blast_Score=224, Evalue=5e-59,
Organism=Caenorhabditis elegans, GI71982038, Length=342, Percent_Identity=37.719298245614, Blast_Score=222, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17568069, Length=326, Percent_Identity=27.6073619631902, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17539532, Length=317, Percent_Identity=25.8675078864353, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI133901786, Length=355, Percent_Identity=24.2253521126761, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115532424, Length=331, Percent_Identity=26.2839879154079, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17539422, Length=355, Percent_Identity=24.2253521126761, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI133901790, Length=355, Percent_Identity=24.2253521126761, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI133901788, Length=355, Percent_Identity=24.2253521126761, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17539424, Length=355, Percent_Identity=24.2253521126761, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=340, Percent_Identity=40, Blast_Score=233, Evalue=4e-62,
Organism=Drosophila melanogaster, GI19923002, Length=345, Percent_Identity=41.1594202898551, Blast_Score=250, Evalue=1e-66,
Organism=Drosophila melanogaster, GI21356223, Length=331, Percent_Identity=28.0966767371601, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36148; Mature: 36017

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKTVLVTGGAGYIGSQAVLSLQRRGYRVIVLDNLVYGHQDLVASVLKAELIVGDTGDR
CCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHCHHHHHHHHHHHHHEECCCCCC
PLLDQIFADHKIDAVMHFAAYAYVGESVTAPGKYYRNNVVGTLTLLEAMVAAGVKQFVFS
HHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHH
STCATYGEPSEIPIPEAHPQNPINPYGMSKLMVEKMLWDFDRAYGLRSVMFRYFNAAGAD
HHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PNGHLGEDHNPETHLIPLVLFAALGKRDSISIFGTNYPTPDGTCVRDYIHVSDLADAHVL
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
GLEYLRQGGVTEAFNLGNGNGFSVKEVIEAARKITAKEIKAIATDRRPGDPPSLVGSSEK
HHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHH
ARTVLGWQPQYADLETILQHAWHWHQQRHG
CCEEECCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADKTVLVTGGAGYIGSQAVLSLQRRGYRVIVLDNLVYGHQDLVASVLKAELIVGDTGDR
CCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHCHHHHHHHHHHHHHEECCCCCC
PLLDQIFADHKIDAVMHFAAYAYVGESVTAPGKYYRNNVVGTLTLLEAMVAAGVKQFVFS
HHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHH
STCATYGEPSEIPIPEAHPQNPINPYGMSKLMVEKMLWDFDRAYGLRSVMFRYFNAAGAD
HHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PNGHLGEDHNPETHLIPLVLFAALGKRDSISIFGTNYPTPDGTCVRDYIHVSDLADAHVL
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
GLEYLRQGGVTEAFNLGNGNGFSVKEVIEAARKITAKEIKAIATDRRPGDPPSLVGSSEK
HHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHH
ARTVLGWQPQYADLETILQHAWHWHQQRHG
CCEEECCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]