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The map label for this gene is upp [H]

Identifier: 170078296

GI number: 170078296

Start: 1772867

End: 1773523

Strand: Reverse

Name: upp [H]

Synonym: SYNPCC7002_A1689

Alternate gene names: 170078296

Gene position: 1773523-1772867 (Counterclockwise)

Preceding gene: 170078299

Following gene: 170078295

Centisome position: 58.96

GC content: 54.19

Gene sequence:

>657_bases
ATGGCTTCGCAACTCCGGGTTTTTGTGCCTGATCATCCCCTCCTCAAGCATTGGTTGGCGATCGCCAGGGAAACCAATAC
CCCCACCCCCCTGTTTAAAACGGCCATGAAAGAACTGGGGAAATGGCTCACCTACGAAGCCTGTCGCTATTGGTTGCCCA
CCCTCGATGCAGCCGTTGAAACCCCTCTCGCCCAGGCCCCAGCCACCTTAATCCATCCCCAAACACCGATTATTGCAATT
CCCATTCTGCGGGCCGGACTTAGTTTGATGGAAGGAGCCCAGGAGGTAATCCCCAACATTGCTGCCACCTACCACCTCGG
CTACAAGCGAGACGAAGCAACCCTTGAAGTGGCTTGCTATCTAAATAATTTGCCAGCGCAATTTGCCCCAGAAACTCGTC
TACTGCTCCTCGATCCGATGTTGGCAACAGGGGGGACGATCACGGCGGCCATGGCTGAAGTGACAAAACGCGGCATTGCC
ATGGAGAATGTGCGCATTATTTCTGTGGTTGCGGCTCCGCCAGCTCTCCAGAAACTGAGTCTAGACTATCCCGCCCTACA
AATTTATACGGCGATGATTGACCAAGAACTAAATGATCAGGGCTTTATCGTGCCCGGTCTCGGGGATGCCGGCGATCGCA
CCTTTGGTACCCACTAA

Upstream 100 bases:

>100_bases
ATCGCAAACTGATCGTGGGGATAGGTGGGGACGCGCATCGGGTTTCATCTAAAAGCTTATGCTAGTCTAAAGGACGGTTC
TTTCTTGATGCAAAACGTCT

Downstream 100 bases:

>100_bases
ACCCTAATGCTGCTGACTCGCAAAGAGACAACGAACAAATCTCCAGGCAAGGGTCATTCCCTGGTAAAAATCTTTGCAAA
CGCACCCTAGTCAAGAGCGA

Product: uracil phosphoribosyltransferase

Products: NA

Alternate protein names: UMP pyrophosphorylase; UPRTase [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MASQLRVFVPDHPLLKHWLAIARETNTPTPLFKTAMKELGKWLTYEACRYWLPTLDAAVETPLAQAPATLIHPQTPIIAI
PILRAGLSLMEGAQEVIPNIAATYHLGYKRDEATLEVACYLNNLPAQFAPETRLLLLDPMLATGGTITAAMAEVTKRGIA
MENVRIISVVAAPPALQKLSLDYPALQIYTAMIDQELNDQGFIVPGLGDAGDRTFGTH

Sequences:

>Translated_218_residues
MASQLRVFVPDHPLLKHWLAIARETNTPTPLFKTAMKELGKWLTYEACRYWLPTLDAAVETPLAQAPATLIHPQTPIIAI
PILRAGLSLMEGAQEVIPNIAATYHLGYKRDEATLEVACYLNNLPAQFAPETRLLLLDPMLATGGTITAAMAEVTKRGIA
MENVRIISVVAAPPALQKLSLDYPALQIYTAMIDQELNDQGFIVPGLGDAGDRTFGTH
>Mature_217_residues
ASQLRVFVPDHPLLKHWLAIARETNTPTPLFKTAMKELGKWLTYEACRYWLPTLDAAVETPLAQAPATLIHPQTPIIAIP
ILRAGLSLMEGAQEVIPNIAATYHLGYKRDEATLEVACYLNNLPAQFAPETRLLLLDPMLATGGTITAAMAEVTKRGIAM
ENVRIISVVAAPPALQKLSLDYPALQIYTAMIDQELNDQGFIVPGLGDAGDRTFGTH

Specific function: Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate [H]

COG id: COG0035

COG function: function code F; Uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPRTase family [H]

Homologues:

Organism=Homo sapiens, GI301129207, Length=205, Percent_Identity=25.3658536585366, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI57863312, Length=205, Percent_Identity=25.3658536585366, Blast_Score=71, Evalue=6e-13,
Organism=Escherichia coli, GI87082118, Length=213, Percent_Identity=38.4976525821596, Blast_Score=139, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6321920, Length=195, Percent_Identity=29.7435897435897, Blast_Score=89, Evalue=5e-19,
Organism=Drosophila melanogaster, GI28573516, Length=205, Percent_Identity=25.8536585365854, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28573514, Length=205, Percent_Identity=25.8536585365854, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28573512, Length=205, Percent_Identity=25.8536585365854, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI45550449, Length=205, Percent_Identity=25.8536585365854, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: 2580 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR005765 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 23796; Mature: 23665

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASQLRVFVPDHPLLKHWLAIARETNTPTPLFKTAMKELGKWLTYEACRYWLPTLDAAVE
CCCCEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TPLAQAPATLIHPQTPIIAIPILRAGLSLMEGAQEVIPNIAATYHLGYKRDEATLEVACY
CCHHHCCHHEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
LNNLPAQFAPETRLLLLDPMLATGGTITAAMAEVTKRGIAMENVRIISVVAAPPALQKLS
ECCCCCCCCCCCEEEEECCHHHCCCHHHHHHHHHHHCCCEECCEEEEEEEECCCHHHHHC
LDYPALQIYTAMIDQELNDQGFIVPGLGDAGDRTFGTH
CCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
ASQLRVFVPDHPLLKHWLAIARETNTPTPLFKTAMKELGKWLTYEACRYWLPTLDAAVE
CCCEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TPLAQAPATLIHPQTPIIAIPILRAGLSLMEGAQEVIPNIAATYHLGYKRDEATLEVACY
CCHHHCCHHEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
LNNLPAQFAPETRLLLLDPMLATGGTITAAMAEVTKRGIAMENVRIISVVAAPPALQKLS
ECCCCCCCCCCCEEEEECCHHHCCCHHHHHHHHHHHCCCEECCEEEEEEEECCCHHHHHC
LDYPALQIYTAMIDQELNDQGFIVPGLGDAGDRTFGTH
CCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]