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The map label for this gene is fmt

Identifier: 170078261

GI number: 170078261

Start: 1733215

End: 1734201

Strand: Direct

Name: fmt

Synonym: SYNPCC7002_A1653

Alternate gene names: 170078261

Gene position: 1733215-1734201 (Clockwise)

Preceding gene: 170078260

Following gene: 170078265

Centisome position: 57.62

GC content: 53.8

Gene sequence:

>987_bases
ATGCTTAAAGTTGTCTTTTTCGGTACGCCTCAGTTTGCAGTGCCCTACCTAGAAGCCCTTTTGAACCACCCGGACATTGA
AGTGCTGGGGGTCGTTACCCAACCGGATAAGCGGCGAGGTCGGGGCAGTCAACTGATTCCGTCGGCGGTAAAAAAGGTGG
CGATCGCCCATGATCTCCCCGTCTGGCAACCGAAGCGCATCAAAAAAGATCCTGAAACCTTAGCGATTCTCGAAAACCTC
CAAGCCGATGTGTTTGCGGTGGTCGCCTACGGGCAGTTGCTCTCGCCGCAAATCCTCCAGATGCCCCGGCTCGGCTGTGT
CAATGGCCATGGTTCCCTGTTGCCGAAATATCGCGGCGCCGCGCCGATCCAGTGGAGTCTCGTCCAGGGGGAAACGGTGA
CGGGGATGACCACCATGCTCATGGATGAGGGGATGGATACCGGGGCAATGCTCCTCAAGGCTGAAACGCCCATTGATCTT
TGGGACAATGCCCATGATTTGGCAGTGAAATTAGCGACCTCCGGGGCGGCTTTATTGACAGAAACGCTCATTCAACTGGC
TCAAGGAAAAATCACCCCCATCCCCCAGGATCCAGACCAAGCCACCTATGCGCCGTTGATTCAGAAAGAAGATTTTCAGC
TAGATTGGCAAAAAGGGGCGATCGCCTTACATAACCAAGTGCGCGGTTTTTATCCCAACTGCCTCACCACCTGCCGCGAT
AAACCGTTAAAAGTGTTAGAAACGATCCCCCTCGTGCCGGAATGTTTTGCGCAATATCCCGCAGCATATGAACCCCTCAA
GGAATTTGTTGGGAACACAGGGAAGGTTGGGGAAATTGTGGCGATCGCCAAAAAATTTGGGCCAATCATCCAAACGGGGG
ACGGACTTTTGTTGCTCAAACAGGTGCAACCCAGCGGCAAAAAACCCCAGTCCGGTTGGGATATGGTCAATGGGATGCGC
CTAACTGTCGGTGAATCCTTGGGCTAG

Upstream 100 bases:

>100_bases
AGCAGTTCAAAAGACCGATGAGGTTTGCATAATCGCTAAGGTCGGGGGAGATCTGCGCTAAAGTGAAAGGCTGATCGCAC
GCTTGGTTGCTCTTTTTCCC

Downstream 100 bases:

>100_bases
AACGCAAAAAAAGTCCCCAGGTTGTGAACCCGGAGACCTTGGGGGAAATTTCAACTTAAAGAACTTATGAAACCCCTTGC
ATTTGTGCTGTTCTCAAGGT

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MLKVVFFGTPQFAVPYLEALLNHPDIEVLGVVTQPDKRRGRGSQLIPSAVKKVAIAHDLPVWQPKRIKKDPETLAILENL
QADVFAVVAYGQLLSPQILQMPRLGCVNGHGSLLPKYRGAAPIQWSLVQGETVTGMTTMLMDEGMDTGAMLLKAETPIDL
WDNAHDLAVKLATSGAALLTETLIQLAQGKITPIPQDPDQATYAPLIQKEDFQLDWQKGAIALHNQVRGFYPNCLTTCRD
KPLKVLETIPLVPECFAQYPAAYEPLKEFVGNTGKVGEIVAIAKKFGPIIQTGDGLLLLKQVQPSGKKPQSGWDMVNGMR
LTVGESLG

Sequences:

>Translated_328_residues
MLKVVFFGTPQFAVPYLEALLNHPDIEVLGVVTQPDKRRGRGSQLIPSAVKKVAIAHDLPVWQPKRIKKDPETLAILENL
QADVFAVVAYGQLLSPQILQMPRLGCVNGHGSLLPKYRGAAPIQWSLVQGETVTGMTTMLMDEGMDTGAMLLKAETPIDL
WDNAHDLAVKLATSGAALLTETLIQLAQGKITPIPQDPDQATYAPLIQKEDFQLDWQKGAIALHNQVRGFYPNCLTTCRD
KPLKVLETIPLVPECFAQYPAAYEPLKEFVGNTGKVGEIVAIAKKFGPIIQTGDGLLLLKQVQPSGKKPQSGWDMVNGMR
LTVGESLG
>Mature_328_residues
MLKVVFFGTPQFAVPYLEALLNHPDIEVLGVVTQPDKRRGRGSQLIPSAVKKVAIAHDLPVWQPKRIKKDPETLAILENL
QADVFAVVAYGQLLSPQILQMPRLGCVNGHGSLLPKYRGAAPIQWSLVQGETVTGMTTMLMDEGMDTGAMLLKAETPIDL
WDNAHDLAVKLATSGAALLTETLIQLAQGKITPIPQDPDQATYAPLIQKEDFQLDWQKGAIALHNQVRGFYPNCLTTCRD
KPLKVLETIPLVPECFAQYPAAYEPLKEFVGNTGKVGEIVAIAKKFGPIIQTGDGLLLLKQVQPSGKKPQSGWDMVNGMR
LTVGESLG

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family

Homologues:

Organism=Homo sapiens, GI21614513, Length=285, Percent_Identity=31.2280701754386, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI238814322, Length=203, Percent_Identity=31.5270935960591, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI164663775, Length=224, Percent_Identity=31.25, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1789683, Length=321, Percent_Identity=41.7445482866044, Blast_Score=211, Evalue=7e-56,
Organism=Escherichia coli, GI1788589, Length=228, Percent_Identity=34.2105263157895, Blast_Score=112, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI133930964, Length=241, Percent_Identity=30.2904564315353, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45550868, Length=323, Percent_Identity=29.7213622291022, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24585660, Length=235, Percent_Identity=29.3617021276596, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28571984, Length=244, Percent_Identity=30.327868852459, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): FMT_SYNP2 (B1XP50)

Other databases:

- EMBL:   CP000951
- RefSeq:   YP_001734899.1
- ProteinModelPortal:   B1XP50
- SMR:   B1XP50
- GeneID:   6056512
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A1653
- HOGENOM:   HBG571560
- OMA:   IMQMDEG
- ProtClustDB:   PRK00005
- HAMAP:   MF_00182
- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR001555
- InterPro:   IPR015518
- Gene3D:   G3DSA:3.10.25.10
- Gene3D:   G3DSA:3.40.50.170
- PANTHER:   PTHR11138
- TIGRFAMs:   TIGR00460

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N; SSF50486 FMT_C_like; SSF53328 formyl_transf

EC number: =2.1.2.9

Molecular weight: Translated: 35747; Mature: 35747

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS00373 GART

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKVVFFGTPQFAVPYLEALLNHPDIEVLGVVTQPDKRRGRGSQLIPSAVKKVAIAHDLP
CEEEEEECCCCHHHHHHHHHHCCCCEEEEEEEECCHHHCCCCCCHHHHHHHHHHHHHCCC
VWQPKRIKKDPETLAILENLQADVFAVVAYGQLLSPQILQMPRLGCVNGHGSLLPKYRGA
CCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEECCCCCCCCCCCCC
APIQWSLVQGETVTGMTTMLMDEGMDTGAMLLKAETPIDLWDNAHDLAVKLATSGAALLT
CCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCCHHCCCCCCEEEEEECCCHHHHH
ETLIQLAQGKITPIPQDPDQATYAPLIQKEDFQLDWQKGAIALHNQVRGFYPNCLTTCRD
HHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCEEECCCCCEEEHHHHCCCCCHHHHHHCC
KPLKVLETIPLVPECFAQYPAAYEPLKEFVGNTGKVGEIVAIAKKFGPIIQTGDGLLLLK
CCHHHHHHCCCCHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEECCCCEEEEE
QVQPSGKKPQSGWDMVNGMRLTVGESLG
ECCCCCCCCCCCHHHHCCEEEECCCCCC
>Mature Secondary Structure
MLKVVFFGTPQFAVPYLEALLNHPDIEVLGVVTQPDKRRGRGSQLIPSAVKKVAIAHDLP
CEEEEEECCCCHHHHHHHHHHCCCCEEEEEEEECCHHHCCCCCCHHHHHHHHHHHHHCCC
VWQPKRIKKDPETLAILENLQADVFAVVAYGQLLSPQILQMPRLGCVNGHGSLLPKYRGA
CCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEECCCCCCCCCCCCC
APIQWSLVQGETVTGMTTMLMDEGMDTGAMLLKAETPIDLWDNAHDLAVKLATSGAALLT
CCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCCHHCCCCCCEEEEEECCCHHHHH
ETLIQLAQGKITPIPQDPDQATYAPLIQKEDFQLDWQKGAIALHNQVRGFYPNCLTTCRD
HHHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCEEECCCCCEEEHHHHCCCCCHHHHHHCC
KPLKVLETIPLVPECFAQYPAAYEPLKEFVGNTGKVGEIVAIAKKFGPIIQTGDGLLLLK
CCHHHHHHCCCCHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEECCCCEEEEE
QVQPSGKKPQSGWDMVNGMRLTVGESLG
ECCCCCCCCCCCHHHHCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA