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The map label for this gene is fur [H]

Identifier: 170078257

GI number: 170078257

Start: 1728610

End: 1729122

Strand: Reverse

Name: fur [H]

Synonym: SYNPCC7002_A1649

Alternate gene names: 170078257

Gene position: 1729122-1728610 (Counterclockwise)

Preceding gene: 170078258

Following gene: 170078256

Centisome position: 57.48

GC content: 51.07

Gene sequence:

>513_bases
ATGCTGGTACCTTCCTACGACGTAAGCGCCCTCAAGACCGAACTCAATGCTAAAGGATGGCGGTTAACGCCCCAGCGGGA
AAAAATTCTCCGCACCTTTCTAAATTTGCCGAAGGGTGAACACCTCAGCGCTGAAGATTTGCACAATGAGTTATTGGAGC
AAGGGGAAAAAATTAGTCTCTCAACGGTGTACCGTAGCGTAAAACTCATGACCCGCATGGGCATTTTACGGGAGCTAGAG
CTCGCCGAGGGCCACAAACATTATGAGCTGAACCAATCCCAAGCCCACCACCACCATTTGGTCTGTGTCCAGTGCAATAA
AACCATTGAGTTTGAGGATGTCGCGATCAACAAACACAGCATTGCCCAATGCCAACAGCAGGGTTTTGAGTTACTCGACT
GCCAGTTAACCATCACCACCATTTGTCCGGAGGCCCGCTTGATGGGTTGGCCCTCGGCGCTCCCCCATGATTGGGTCTGT
TCGCGGGAAAAAGCCCAAACCCATCTCCATTAA

Upstream 100 bases:

>100_bases
GGTGACCTGAATGTTAGTATTTATTTGCAATAAGGCCAGATTGTTGCAAAAGTAGAAAAGGGCGTTTATTATTGTCAATA
AGCTGAACTTGTTGAAAAAT

Downstream 100 bases:

>100_bases
TCGAGGCGATCGCATTTGACGGTAACATTGCAGTCCCAATCTTTATTGGTGACGGAAAATTTAACGGTGGGCTACCAACG
GCGTGCCTTACTTCAAGATC

Product: ferric uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MLVPSYDVSALKTELNAKGWRLTPQREKILRTFLNLPKGEHLSAEDLHNELLEQGEKISLSTVYRSVKLMTRMGILRELE
LAEGHKHYELNQSQAHHHHLVCVQCNKTIEFEDVAINKHSIAQCQQQGFELLDCQLTITTICPEARLMGWPSALPHDWVC
SREKAQTHLH

Sequences:

>Translated_170_residues
MLVPSYDVSALKTELNAKGWRLTPQREKILRTFLNLPKGEHLSAEDLHNELLEQGEKISLSTVYRSVKLMTRMGILRELE
LAEGHKHYELNQSQAHHHHLVCVQCNKTIEFEDVAINKHSIAQCQQQGFELLDCQLTITTICPEARLMGWPSALPHDWVC
SREKAQTHLH
>Mature_170_residues
MLVPSYDVSALKTELNAKGWRLTPQREKILRTFLNLPKGEHLSAEDLHNELLEQGEKISLSTVYRSVKLMTRMGILRELE
LAEGHKHYELNQSQAHHHHLVCVQCNKTIEFEDVAINKHSIAQCQQQGFELLDCQLTITTICPEARLMGWPSALPHDWVC
SREKAQTHLH

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=133, Percent_Identity=36.8421052631579, Blast_Score=80, Evalue=5e-17,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 19553; Mature: 19553

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVPSYDVSALKTELNAKGWRLTPQREKILRTFLNLPKGEHLSAEDLHNELLEQGEKISL
CCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHH
STVYRSVKLMTRMGILRELELAEGHKHYELNQSQAHHHHLVCVQCNKTIEFEDVAINKHS
HHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCEEEEEEECCCEEEEEEEECCHHH
IAQCQQQGFELLDCQLTITTICPEARLMGWPSALPHDWVCSREKAQTHLH
HHHHHHCCCEEEEEEEEEEEECCCHHHCCCCCCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MLVPSYDVSALKTELNAKGWRLTPQREKILRTFLNLPKGEHLSAEDLHNELLEQGEKISL
CCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCHH
STVYRSVKLMTRMGILRELELAEGHKHYELNQSQAHHHHLVCVQCNKTIEFEDVAINKHS
HHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCEEEEEEECCCEEEEEEEECCHHH
IAQCQQQGFELLDCQLTITTICPEARLMGWPSALPHDWVCSREKAQTHLH
HHHHHHCCCEEEEEEEEEEEECCCHHHCCCCCCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]