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The map label for this gene is rcsC [H]

Identifier: 170078249

GI number: 170078249

Start: 1721145

End: 1722383

Strand: Direct

Name: rcsC [H]

Synonym: SYNPCC7002_A1641

Alternate gene names: 170078249

Gene position: 1721145-1722383 (Clockwise)

Preceding gene: 170078248

Following gene: 170078251

Centisome position: 57.22

GC content: 51.01

Gene sequence:

>1239_bases
ATGCGAACCCCCGAACCTTTGCCCCATGAAGCAGAACGCCTCAAATCATTGTTCCAACAGGATCTTTTAGATACCCCCCA
GGAGCCTGAATTTAATCGCATTGTCAACCTCGCGGCGCGACTGTTTGGGGTCAAAATCGTTTTGATTTCCCTCGTGGATG
ATTGTCGGCAGTGGTTTAAGGCTAAGGTCGGCTTGGCAGCGAGCGAAACCCCCCGCAATATTTCCTTTTGTGGCCACGCA
ATTCAGAGGGCAGACATTTTTGAAATCCCGGATACCTTAGCCGATGAACGCTTTTGGGACAATCCCCTTGTCACTGGAAA
ACCCTATATTCGTTTCTATGCGGGTCATCCCATCCGCTCTGGGGACGGCTATCCCCTGGGTACCCTGTGTTTAATTGATG
AACAACCCCGTAAATTGACGGCCACTGAACGGGAACTGCTGCAAATGCTGGCGCACCAGGTAGAAGATTTGCTCCGTTTA
CGCCGTAATCTAAAACGCAAGCAAAACAAAATTAAGCTGCTCACGGTGCAAGTACAATCCCTAGATCGAAGCAATAACCT
CAAGGATCAACTGTTAGCGGTGTTGTCCCACGATCTGCGCAGTCCCCTGATTAGTTTCCGGTCGGTGATAGAACTCTTGG
CCGCCCAGGCCCTAGAGCCGGAGGAGCTAGAAATTTTAATTCCCGAAGTCTGCAACAAGTTTGACCAAACAGAAATGAAG
GTGATGCAGATGTTGCAATGGGCGCAGCAGCAACTCCAGACGGAAGTGGTTCCCATTGAGATGATCAAAGTCGAGGCGAT
CGCCGCCCATGTGTTGCCCTGGTGCCAGGACTGCGCCCAACGAAAAAATGTGACCTTACAAGTTGAAATGGAGCCCCAAT
TACAAGTCCTAGGCAATTTAGAGCTTATCGGGGTTGTGCTGCGTAATTTCCTGGGCAATGCGGTGAAATATTCCCGTCAC
GGTGAAACGATCACCTTGTTCGCGCGCCGGAGTGGTCAATATGTAGAATTGGGGGTTCGGGATACGGGGCTGGGAATGAA
GCCCGAAACCCTTAAAAAAATTCGTAGCCATAGCTATCAGCTGTCAGCCCCAGGCACCGACAATGAAAAAGGGACTGGCC
TGGGGTTATTGCTCTGTCAGACTTACCTCAACCAGATGGGCACTGCCCTAGAGATTGAAAGCCGTTGGATGGAAGGATCG
ACGTTTTCGTTTCGCTTGCCGATCGCCCCCAGTGCCTAG

Upstream 100 bases:

>100_bases
AGGCTCCTTTGAGGTTTCAGGGGCGCACAAAATATTTCTAGTTTGGGTACCTTGGAGAGAGAAAATAATCTTTTCACAGC
AGTAAGGAAATCCTGAAGTG

Downstream 100 bases:

>100_bases
AGGGTCACTTGACCCTGGAAGCTAATGGCTGCTGGCCCGGTCATATAGATGTGATTGTCTGCTGCTGACCATTCGATCTG
GAGACAGCCCCCCGGTAGTT

Product: two-component hybrid sensor and regulator

Products: NA

Alternate protein names: Capsular synthesis regulator component C [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MRTPEPLPHEAERLKSLFQQDLLDTPQEPEFNRIVNLAARLFGVKIVLISLVDDCRQWFKAKVGLAASETPRNISFCGHA
IQRADIFEIPDTLADERFWDNPLVTGKPYIRFYAGHPIRSGDGYPLGTLCLIDEQPRKLTATERELLQMLAHQVEDLLRL
RRNLKRKQNKIKLLTVQVQSLDRSNNLKDQLLAVLSHDLRSPLISFRSVIELLAAQALEPEELEILIPEVCNKFDQTEMK
VMQMLQWAQQQLQTEVVPIEMIKVEAIAAHVLPWCQDCAQRKNVTLQVEMEPQLQVLGNLELIGVVLRNFLGNAVKYSRH
GETITLFARRSGQYVELGVRDTGLGMKPETLKKIRSHSYQLSAPGTDNEKGTGLGLLLCQTYLNQMGTALEIESRWMEGS
TFSFRLPIAPSA

Sequences:

>Translated_412_residues
MRTPEPLPHEAERLKSLFQQDLLDTPQEPEFNRIVNLAARLFGVKIVLISLVDDCRQWFKAKVGLAASETPRNISFCGHA
IQRADIFEIPDTLADERFWDNPLVTGKPYIRFYAGHPIRSGDGYPLGTLCLIDEQPRKLTATERELLQMLAHQVEDLLRL
RRNLKRKQNKIKLLTVQVQSLDRSNNLKDQLLAVLSHDLRSPLISFRSVIELLAAQALEPEELEILIPEVCNKFDQTEMK
VMQMLQWAQQQLQTEVVPIEMIKVEAIAAHVLPWCQDCAQRKNVTLQVEMEPQLQVLGNLELIGVVLRNFLGNAVKYSRH
GETITLFARRSGQYVELGVRDTGLGMKPETLKKIRSHSYQLSAPGTDNEKGTGLGLLLCQTYLNQMGTALEIESRWMEGS
TFSFRLPIAPSA
>Mature_412_residues
MRTPEPLPHEAERLKSLFQQDLLDTPQEPEFNRIVNLAARLFGVKIVLISLVDDCRQWFKAKVGLAASETPRNISFCGHA
IQRADIFEIPDTLADERFWDNPLVTGKPYIRFYAGHPIRSGDGYPLGTLCLIDEQPRKLTATERELLQMLAHQVEDLLRL
RRNLKRKQNKIKLLTVQVQSLDRSNNLKDQLLAVLSHDLRSPLISFRSVIELLAAQALEPEELEILIPEVCNKFDQTEMK
VMQMLQWAQQQLQTEVVPIEMIKVEAIAAHVLPWCQDCAQRKNVTLQVEMEPQLQVLGNLELIGVVLRNFLGNAVKYSRH
GETITLFARRSGQYVELGVRDTGLGMKPETLKKIRSHSYQLSAPGTDNEKGTGLGLLLCQTYLNQMGTALEIESRWMEGS
TFSFRLPIAPSA

Specific function: Member of the two-component regulatory system RcsC/RcsB involved in the regulation of the expression of genes involved in colanic acid capsule synthesis. Together with RcsF, RcsC probably functions as a membrane-associated protein kinase that phosphorylat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=236, Percent_Identity=27.9661016949153, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1786600, Length=220, Percent_Identity=26.8181818181818, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1789149, Length=297, Percent_Identity=23.5690235690236, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI48994928, Length=243, Percent_Identity=25.1028806584362, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=23.9819004524887, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788549, Length=223, Percent_Identity=26.0089686098655, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788393, Length=204, Percent_Identity=21.078431372549, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR019017
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09456 RcsC; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46784; Mature: 46784

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTPEPLPHEAERLKSLFQQDLLDTPQEPEFNRIVNLAARLFGVKIVLISLVDDCRQWFK
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKVGLAASETPRNISFCGHAIQRADIFEIPDTLADERFWDNPLVTGKPYIRFYAGHPIRS
HHCCCCCCCCCCCHHHHHHHHHHCCHHCCCHHHHCCHHCCCCCCCCCCCEEEEECCCCCC
GDGYPLGTLCLIDEQPRKLTATERELLQMLAHQVEDLLRLRRNLKRKQNKIKLLTVQVQS
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEC
LDRSNNLKDQLLAVLSHDLRSPLISFRSVIELLAAQALEPEELEILIPEVCNKFDQTEMK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEHHHHCCCCCHHHHH
VMQMLQWAQQQLQTEVVPIEMIKVEAIAAHVLPWCQDCAQRKNVTLQVEMEPQLQVLGNL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHCCH
ELIGVVLRNFLGNAVKYSRHGETITLFARRSGQYVELGVRDTGLGMKPETLKKIRSHSYQ
HHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHCCEE
LSAPGTDNEKGTGLGLLLCQTYLNQMGTALEIESRWMEGSTFSFRLPIAPSA
EECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEHHHHCCCCCEEEEECCCCCC
>Mature Secondary Structure
MRTPEPLPHEAERLKSLFQQDLLDTPQEPEFNRIVNLAARLFGVKIVLISLVDDCRQWFK
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKVGLAASETPRNISFCGHAIQRADIFEIPDTLADERFWDNPLVTGKPYIRFYAGHPIRS
HHCCCCCCCCCCCHHHHHHHHHHCCHHCCCHHHHCCHHCCCCCCCCCCCEEEEECCCCCC
GDGYPLGTLCLIDEQPRKLTATERELLQMLAHQVEDLLRLRRNLKRKQNKIKLLTVQVQS
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEC
LDRSNNLKDQLLAVLSHDLRSPLISFRSVIELLAAQALEPEELEILIPEVCNKFDQTEMK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEHHHHCCCCCHHHHH
VMQMLQWAQQQLQTEVVPIEMIKVEAIAAHVLPWCQDCAQRKNVTLQVEMEPQLQVLGNL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHCCH
ELIGVVLRNFLGNAVKYSRHGETITLFARRSGQYVELGVRDTGLGMKPETLKKIRSHSYQ
HHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHCCEE
LSAPGTDNEKGTGLGLLLCQTYLNQMGTALEIESRWMEGSTFSFRLPIAPSA
EECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEHHHHCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2404948; 8366025; 9097040; 9278503; 11758943; 11309126; 13129944 [H]